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Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients

NCT07469124 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2026-03-13

No results posted yet for this study

Summary

The goal of this clinical trial is to examine the clinical success of different pre-treatments in resin infiltration therapy applied to the incisors of pediatric patients with Molar Incisor Hypomineralization (MIH) and to evaluate the impact of treatment on the quality of life of children. The main questions that this study aims to answer are:

* Does resin infiltration therapy improve the color and surface appearance of incisors affected by MIH?
* Is there a reduction in tooth sensitivity after treatment?
* Are patients and their parents satisfied with the treatment results?
* Is there an improvement in the quality of life of children after treatment?

Researchers will apply resin infiltration therapy to incisors affected by MIH and evaluate the results over a 12-month follow-up period. Participants will:

* Receive resin infiltration therapy on their MIH incisors.
* Attend follow-up appointments at 1, 3, 6, 9, and 12 months.
* At the follow-up appointments, the teeth will be evaluated with clinical examination and photographs.
* Participants will complete questionnaires regarding tooth sensitivity and quality of life related to oral health.

The results of this study are expected to contribute to the development of minimally invasive treatment options for children with MIH.

Conditions

  • Molar Incisor Hypomineralization

Interventions

PROCEDURE

Resin Infiltration

A minimally invasive treatment in which a low-viscosity resin material is applied to porous enamel lesions to reduce opacity, improve clinical appearance, and stabilize the enamel surface.

PROCEDURE

Microabrasion Followed by Resin Infiltration

A combined treatment protocol involving enamel microabrasion prior to resin infiltration to evaluate its effect on treatment efficacy, lesion appearance, and clinical outcomes in hypomineralized enamel lesions.

PROCEDURE

Air Abrasion Followed by Resin Infiltration

A combined minimally invasive treatment in which air abrasion is used for enamel surface preparation prior to resin infiltration to optimize resin penetration and improve esthetic and clinical outcomes in hypomineralized lesions.

Sponsors & Collaborators

  • Inonu University

    lead OTHER

Principal Investigators

  • Zekiye Şeyma Gümüşboğa, Assistant Professor · Inonu University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
6 Years
Max Age
14 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-01
Primary Completion
2027-01-31
Completion
2027-02-15

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07469124 on ClinicalTrials.gov