Clinical Trials Updated in 2026

NCT07079475 | RECRUITING | PHASE1/PHASE2

220 participants

Study of Oral EGFR Inhibitor DZD6008 Combined With Sunvozertinib in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN8)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-30
Completion:: 2028-06-30

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07077161 | RECRUITING | PHASE2

34 participants

Cabozantinib Dose Skipping as an Alternative to Dose Reductions

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-01-26
Completion:: 2027-09-01

Conditions

Renal Cell Carcinoma (RCC)

Interventions

DRUG

No Results Yet

NCT07076550 | TERMINATED | PHASE1

5 participants

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-11-19
Completion:: 2026-07-09

Conditions

Melanoma Metastatic
Uveal Melanoma, Metastatic
Mucosal Melanoma

Interventions

DRUG
DIAGNOSTIC_TEST

No Results Yet

NCT07070661 | COMPLETED | NA

44 participants

Radial Pressure Wave Therapy With or Without Parameter Modulation for Carpal Tunnel Syndrome.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-15
Completion:: 2026-01-15

Conditions

Carpal Tunnel Syndrome (CTS)

Interventions

DEVICE

No Results Yet

NCT07070440 | RECRUITING | PHASE1/PHASE2

180 participants

DZD6008 Combination Therapy in Patients With Locally Advanced or Metastatic NSCLC With EGFR Mutation (TIAN-SHAN7)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-16
Completion:: 2027-06-30

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07062315 | ENROLLING_BY_INVITATION | NA

90 participants

Impact of Chronotype-Based Time-Restricted Eating on Visceral Fat and Metabolic Health in Physically Inactive Adults With Central Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-31
Completion:: 2026-10-31

Conditions

Central Obesity
Time Restricted Eating

Interventions

BEHAVIORAL

No Results Yet

NCT07061964 | RECRUITING | PHASE2

111 participants

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-11-25
Completion:: 2027-07-31

Conditions

Muscle Invasive Bladder Urothelial Carcinoma
Stage II Bladder Cancer AJCC v8
Stage IIIA Bladder Cancer AJCC v8

Interventions

PROCEDURE
BIOLOGICAL
RADIATION
OTHER

No Results Yet

NCT07057336 | COMPLETED | NA

90 participants

Evaluation of Post-Operative Pain Following the Use of Nano-Calcium Hydroxide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-05-14
Completion:: 2024-12-15

Conditions

Chronic Apical Periodontitis

Interventions

DRUG

No Results Yet

NCT07054190 | RECRUITING | PHASE2

120 participants

A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-09-09
Completion:: 2027-07-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT07053514 | NOT_YET_RECRUITING | NA

139 participants

Same-Day Antiretroviral Therapy as a Behavioral Design Intervention to Reduce Stigma in Key Affected Populations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2027-10-31
Completion:: 2028-10-31

Conditions

Hiv

Interventions

BEHAVIORAL

No Results Yet

NCT07045038 | COMPLETED | NA

60 participants

Blood Flow Restricted Resistance Exercises Versus Low Level Laser on Cardiac Functions in Patients With Chronic Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-20
Completion:: 2026-04-20

Conditions

Heart Failure NYHA Class II

Interventions

DEVICE
OTHER
DRUG

No Results Yet

NCT07042295 | SUSPENDED | PHASE2

86 participants

Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-03-23
Completion:: 2029-02-28

Conditions

Locally Recurrent Skin Squamous Cell Carcinoma
Metastatic Skin Squamous Cell Carcinoma

Interventions

DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT07041723 | RECRUITING | NA

6 participants

BiOfeedback, Online for Sibilant Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-30
Completion:: 2027-07-31

Conditions

Speech Sound Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07041125 | COMPLETED

122 participants

Concomitant LAAC/AF Ablation (Watchman FLX Pro)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-06-01
Completion:: 2026-06-30

Conditions

PFA Ablation and LAAC Procedures

Interventions

DEVICE

No Results Yet

NCT07030868 | TERMINATED | PHASE2

1 participants

A Study of LY3549492 in Adults With Obesity or Overweight With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-06-19
Completion:: 2025-07-29

Conditions

Obesity
Overweight
Type 2 Diabetes

Interventions

DRUG

Results Available

NCT07019649 | COMPLETED | NA

21 participants

Randomized Pilot Trial of AYUDA Program for Younger Latinx Adults With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-25
Completion:: 2026-06-09

Conditions

Diabetes Mellitus, Type 2

Interventions

BEHAVIORAL

No Results Yet

NCT07015034 | RECRUITING | NA

460 participants

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-05-15
Completion:: 2026-10-30

Conditions

Vision Impairment and Blindness
Glaucoma
Age-Related Macular Degeneration
Cataract
Diabetic Retinopathy

Interventions

OTHER

No Results Yet

NCT07013201 | RECRUITING | PHASE2

135 participants

A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-09-11
Completion:: 2026-12-14

Conditions

Palmoplantar Pustulosis

Interventions

DRUG

No Results Yet

NCT07010302 | NOT_YET_RECRUITING | PHASE4

540 participants

Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-08-01
Completion:: 2030-01-31

Conditions

NMOSD

Interventions

DRUG

No Results Yet

NCT07004699 | RECRUITING | NA

610 participants

Comparison of Two Ventilation Methods During Endoscopy of the Pharynx, Larynx and Oesophagus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-11
Completion:: 2027-07-01

Conditions

Oxygen Inhalation Therapy Endoscopy

Interventions

PROCEDURE

No Results Yet

NCT06995651 | RECRUITING | PHASE1

15 participants

Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-10-21
Completion:: 2027-07-31

Conditions

Pancreatic Insufficiency
Cystic Fibrosis-related Diabetes

Interventions

DRUG

No Results Yet

NCT06995521 | RECRUITING | PHASE2

55 participants

Vorinostat for Graft-versus-host Disease (GVHD) Prevention in Non-Malignant Adolescent and Young Adults (AYA) Population

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-09-30
Completion:: 2028-09-30

Conditions

GVHD

Interventions

DRUG

No Results Yet

NCT06991556 | ACTIVE_NOT_RECRUITING | PHASE2

167 participants

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-07
Completion:: 2032-02-13

Conditions

Metastatic Hormone-sensitive Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06990737 | WITHDRAWN | PHASE2

0 participants

Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-06-25
Completion:: 2026-06-18

Conditions

Cutaneous Squamous Cell Carcinoma of the Head and Neck
Clinically Node-Negative (cN0)
High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06985641 | ACTIVE_NOT_RECRUITING | NA

119 participants

Khanya Ekhaya: A Home-Based Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-08-17
Completion:: 2026-11-23

Conditions

Mental Health
Community Health Workers
Training
Global Health
Burnout
Well-being
Natured-informed Therapy

Interventions

BEHAVIORAL

No Results Yet

NCT06981923 | COMPLETED | NA

350 participants

Awake Video Stylet Airway Assessment and Evaluation of Tracheal Intubation With CMAC D-Blade Versus Video Stylet in Bariatric Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-05-10
Completion:: 2026-02-10

Conditions

Difficult Intubation in Obesity

Interventions

DEVICE

No Results Yet

NCT06976190 | RECRUITING | PHASE3

446 participants

A Study of MRG003 in Combination With Pucotenlimab Versus Chemotherapy in the Treatment of Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-05-06
Completion:: 2029-05-31

Conditions

Recurrent or Metastatic Nasopharyngeal Carcinoma

Interventions

DRUG

No Results Yet

NCT06974916 | RECRUITING | NA

100 participants

EMBRACE Tremor BiFUS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-04-22
Completion:: 2027-07-31

Conditions

Essential Tremor

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06968806 | RECRUITING | PHASE3

1346 participants

Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-10-27
Completion:: 2027-09-01

Conditions

Aortic Dissection
Inflammation

Interventions

DRUG

No Results Yet

NCT06966362 | RECRUITING | PHASE4

400 participants

Varenicline for Smoking Reduction in Veterans Not Ready To Quit

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-08-17
Completion:: 2030-06-28

Conditions

Veterans
Tobacco Use Disorder
Cigarette Smoking
Tobacco Dependence

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT06966193 | COMPLETED

30 participants

Co-Producing LGBTQ-Affirmative DBT Protocols.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-10-01
Completion:: 2026-04-30

Conditions

Self-Harm
Suicidal
Emotional Dysregulation

No Results Yet

NCT06953466 | RECRUITING | PHASE2/PHASE3

8 participants

Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-10-06
Completion:: 2026-12-30

Conditions

Netherton Syndrome

Interventions

DRUG

No Results Yet

NCT06944002 | COMPLETED | NA

9 participants

Milk Consumption and Blood Microbiome in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-10
Completion:: 2025-09-08

Conditions

Healthy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06943859 | RECRUITING | PHASE2

50 participants

Ketamine for Opioid Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-02-04
Completion:: 2028-08-31

Conditions

Opioid Use Disorder

Interventions

DRUG

No Results Yet

NCT06943287 | COMPLETED | NA

80 participants

Pharmacist Intervention to Improve Smoking Cessation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-08-11
Completion:: 2026-07-06

Conditions

Smoking Cessation

Interventions

BEHAVIORAL

Results Available

NCT06940180 | RECRUITING | PHASE2

20 participants

Toripalimab With Chemotherapy for Sinus Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-06-17
Completion:: 2028-02-01

Conditions

Sinonasal Cancer
Paranasal Sinus Neoplasms
Squamous Cell Carcinoma
Sinonasal Undifferentiated Carcinoma
Locally Advanced Head and Neck Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT06938100 | RECRUITING

100 participants

Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASIL

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2023-11-21
Completion:: 2027-04-30

Conditions

CADASIL
CADASIL (Diagnosis)

No Results Yet

NCT06926478 | NOT_YET_RECRUITING | PHASE1

8 participants

Subconjunctival Humira for Boston Keratoprosthesis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-10-01
Completion:: 2027-06-01

Conditions

Penetrating Keratoplasty
Multiple Graft Failure
Ocular Cicatricial Pemphigoid
Stevens-Johnson Syndrome

Interventions

DRUG

No Results Yet

NCT06920355 | ACTIVE_NOT_RECRUITING | NA

610 participants

Community Pharmacy Produce Prescriptions

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-05-22
Completion:: 2026-12-31

Conditions

Diabetes Mellitus Type 2
Hypertension

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT06919926 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-04-17
Completion:: 2027-05-31

Conditions

Hippocampal Overactivity
Dementia

Interventions

DRUG

No Results Yet