Clinical Trials

NCT04181827 | ACTIVE_NOT_RECRUITING | PHASE3

419 participants

A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-06-12

Completion:

2024-05-01

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT04145115 | ACTIVE_NOT_RECRUITING | PHASE2

37 participants

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-12-24

Completion:

2026-12-31

Conditions

• Astrocytoma, IDH-Mutant, Grade 4
• Diffuse Glioma
• Glioblastoma, IDH-Wildtype
• Secondary Glioblastoma

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT04133636 | ACTIVE_NOT_RECRUITING | PHASE2

208 participants

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-11-07

Completion:

2027-02-26

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT04119050 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

118 participants

Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-08-15

Completion:

2025-02-02

Conditions

• Warm Autoimmune Hemolytic Anemia

Interventions

• DRUG

No Results Yet

NCT04071236 | SUSPENDED | PHASE1/PHASE2

90 participants

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-10-14

Completion:

2027-04-30

Conditions

• Metastatic Castration-Resistant Prostate Carcinoma
• Metastatic Malignant Neoplasm in the Bone
• Metastatic Malignant Neoplasm in the Lymph Nodes
• Stage IVB Prostate Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• OTHER
• RADIATION

No Results Yet

NCT04061720 | COMPLETED | NA

502 participants

Identifying Effective Treatment for Veterans Unwilling to Quit Smoking

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-11-12

Completion:

2025-09-26

Conditions

• Tobacco Dependence
• Veterans

Interventions

• BEHAVIORAL

Results Available

NCT04055077 | COMPLETED | NA

176 participants

Influence of HFNO on Spontaneous Breathing Support in Patients of Different ASA Risk During Moderate Multimodal Analgo-sedation for Pars Plana Vitrectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-06-01

Completion:

2023-06-01

Conditions

• Hypoxia
• Pars Plana Vitrectomy
• Respiratory Complications

Interventions

• DEVICE

No Results Yet

NCT04044001 | COMPLETED | PHASE1/PHASE2

78 participants

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-11-15

Completion:

2022-03-03

Conditions

• Pulmonary Tuberculoses
• Other Specified Pulmonary Tuberculosis

Interventions

• DRUG

Results Available

NCT04033445 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

1064 participants

A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-09-26

Completion:

2023-09-19

Conditions

• Ulcerative Colitis

Interventions

• DRUG

Results Available

NCT04006522 | ACTIVE_NOT_RECRUITING | PHASE2

46 participants

89Zr-DFO-Atezolizumab ImmunoPET/CT in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-10-02

Completion:

2026-08-06

Conditions

• Renal Cell Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03995966 | ACTIVE_NOT_RECRUITING | NA

16 participants

A Clinical Trial for Self-Injurious Behavior

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-06-04

Completion:

2025-09-09

Conditions

• Self-Injurious Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT03988595 | ACTIVE_NOT_RECRUITING | PHASE1

54 participants

Exercise Treatment With Standard Therapy for Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-06-12

Completion:

2027-08-01

Conditions

• Hormone Receptor Positive Metastatic Breast Cancer

Interventions

• OTHER

No Results Yet

NCT03977753 | RECRUITING | PHASE4

162 participants

Randomized, Placebo-controlled, Double Blind Study to Evaluate the Efficacy of 2LVERU®JUNIOR and 2LVERU® on the Treatment of Warts

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-02-17

Completion:

2028-12-16

Conditions

• Common Wart
• Flat Wart
• Plantar Wart

Interventions

• DRUG

No Results Yet

NCT03973281 | COMPLETED | NA

420 participants

EASE: The Materna Prep Pivotal Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-12-11

Completion:

2026-07-30

Conditions

• Vaginal Delivery
• Pelvic Organ Prolapse

Interventions

• DEVICE
• OTHER

No Results Yet

NCT03948724 | COMPLETED | NA

412 participants

Impact of Therapeutic Patient Education on the Toxicity of Immune Checkpoint Inhibitors in Oncology

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-12-11

Completion:

2023-08-04

Conditions

• Therapeutic Patient Education
• Immune Checkpoint Inhibitors
• Melanoma
• Advanced Non-small Cell Lung Cancer
• Renal Cell Carcinoma
• Head and Neck Cancer
• Immune-related Adverse Event

Interventions

• BEHAVIORAL

Results Available

NCT03944226 | COMPLETED | NA

1 participants

Is Dietary Nitrate Effective in Reducing Aerobic Glycolysis in Breast Cancer?

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-08-01

Completion:

2022-11-28

Conditions

• Malignant Breast Tissue Neoplasm

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT03923205 | COMPLETED | NA

28 participants

Assessing the Effects of a Buckwheat Beverage on Postprandial Glucose Metabolism on Healthy and T2D Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-03-07

Completion:

2022-03-31

Conditions

• Healthy
• Type2 Diabetes

Interventions

• OTHER

No Results Yet

NCT03827343 | ACTIVE_NOT_RECRUITING

500 participants

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2019-01-23

Completion:

2026-12-31

Conditions

• Macrophage Activation Syndrome
• Primary Hemophagocytic Lymphohistiocytosis

No Results Yet

NCT03793166 | ACTIVE_NOT_RECRUITING | PHASE3

1175 participants

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-06-07

Completion:

2028-01-25

Conditions

• Clear Cell Renal Cell Carcinoma
• Metastatic Malignant Neoplasm in the Bone
• Metastatic Malignant Neoplasm in the Lymph Nodes
• Metastatic Malignant Neoplasm in the Soft Tissue
• Metastatic Malignant Neoplasm in the Viscera
• Rhabdoid Tumor of the Kidney
• Sarcomatoid Renal Cell Carcinoma
• Stage III Renal Cell Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT03776162 | ACTIVE_NOT_RECRUITING | NA

150 participants

A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-08-30

Completion:

2027-07-31

Conditions

• Anterior Cruciate Ligament Tear

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT03745339 | RECRUITING

150 participants

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2019-06-07

Completion:

2026-10-01

Conditions

• Opioid-Related Disorders
• Drug Addiction

No Results Yet

NCT03743766 | COMPLETED | PHASE2

43 participants

Nivolumab, BMS-936558 in Combination With Relatlimab, BMS-986016 in Patients With Metastatic Melanoma Naïve to Prior Immunotherapy in the Metastatic Setting

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-03-29

Completion:

2024-07-03

Conditions

• Melanoma

Interventions

• DRUG

Results Available

NCT03737214 | ACTIVE_NOT_RECRUITING | PHASE3

107 participants

A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-12-18

Completion:

2029-08-31

Conditions

• Fabry Disease

Interventions

• DRUG

No Results Yet

NCT03684317 | WITHDRAWN

0 participants

Primary Dependence to Analgesic Drugs

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2019-06-01

Completion:

2023-04-30

Conditions

• Addiction

No Results Yet

NCT03683251 | RECRUITING | PHASE3

1000 participants

Extension Study for the Port Delivery System With Ranibizumab (Portal)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-09-20

Completion:

2029-12-31

Conditions

• Neovascular Age-Related Macular Degeneration

Interventions

• DRUG

No Results Yet

NCT03652428 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

24 participants

Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-04-02

Completion:

2026-12-31

Conditions

• Locally Advanced Pancreatic Cancer

Interventions

• DRUG
• RADIATION

No Results Yet

NCT03596645 | ACTIVE_NOT_RECRUITING | PHASE3

84 participants

A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-10-29

Completion:

2023-11-21

Conditions

• Colitis, Ulcerative

Interventions

• DRUG

Results Available

NCT03535298 | ACTIVE_NOT_RECRUITING | PHASE4

800 participants

Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-01-03

Completion:

2027-07-30

Conditions

• Multiple Sclerosis, Relapsing-Remitting

Interventions

• DRUG

No Results Yet

NCT03534245 | COMPLETED

775 participants

Investigating Vector-Borne Determinants of Aedes Transmitted Arboviral Infections in Cambodia: An Observational Longitudinal Cohort Study in Children

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2018-07-01

Completion:

2022-01-25

Conditions

• Dengue Fever

No Results Yet

NCT03505320 | ACTIVE_NOT_RECRUITING | PHASE2

143 participants

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-06-29

Completion:

2027-06-30

Conditions

• Pharmacokinetics of Zolbetuximab
• Gastric Cancer
• Gastro-esophageal Junction (GEJ) Cancer
• Pharmacokinetics of Oxaliplatin
• Pharmacokinetics of Fluorouracil Bolus (5-FU)

Interventions

• DRUG

No Results Yet

NCT03480633 | RECRUITING

3000 participants

Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2016-04-07

Completion:

2028-10-31

Conditions

• Heart Failure With Normal Ejection Fraction
• Heart Failure With Reduced Ejection Fraction
• Heart Failure, Right Sided
• Heart Failure With Mid Range Ejection Fraction
• Cardiovascular Risk Factor

No Results Yet

NCT03466411 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

1409 participants

A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-04-13

Completion:

2023-10-20

Conditions

• Crohn's Disease

Interventions

• DRUG

Results Available

NCT03462719 | ACTIVE_NOT_RECRUITING | PHASE3

211 participants

A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-04-17

Completion:

2021-02-26

Conditions

• Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

• DRUG

Results Available

NCT03451851 | ACTIVE_NOT_RECRUITING | PHASE3

120 participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-07-11

Completion:

2023-07-19

Conditions

• Psoriasis

Interventions

• DRUG

Results Available

NCT03407066 | RECRUITING

10200 participants

Perception, Sensation, Cognition and Action in Humans

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2019-03-26

Completion:

2035-12-31

Conditions

• Normal Physiology

No Results Yet

NCT03402139 | COMPLETED

163 participants

Early Childhood Obesity Programming by Intrauterine Growth Restriction

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2018-09-01

Completion:

2021-12-19

Conditions

• Childhood Obesity
• Epigenetics

No Results Yet

NCT03394066 | RECRUITING | NA

95 participants

Mechanism of Non-invasive Magnetic Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-09-19

Completion:

2028-12-31

Conditions

• Healthy Volunteers

Interventions

• DEVICE

No Results Yet

NCT03372733 | RECRUITING | PHASE2

110 participants

Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-07-31

Completion:

2027-07-31

Conditions

• Cardiovascular Disease

Interventions

• DRUG

No Results Yet

NCT03367728 | COMPLETED | PHASE4

148 participants

The Use of Laparoscopic Transversus Abdominis Plane Block in Gastric Bypass Surgery (LapTAP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-11-27

Completion:

2020-02-28

Conditions

• Bariatric Surgery Candidate

Interventions

• DRUG

No Results Yet

NCT03330158 | COMPLETED | NA

5 participants

Clinical Assessment of a Motorized Spinal Distraction Rod in the Severe to Early Scoliosis Child

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2019-02-05

Completion:

2025-12-31

Conditions

• Scoliosis

Interventions

• DEVICE

No Results Yet