Clinical Trials Updated in 2026

NCT07107958 | COMPLETED | NA

200 participants

Electroacupuncture-Induced Changes in Tongue Features in Early Stroke Patients Using ZMT-1A Imaging System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-01
Completion:: 2025-07-25

Conditions

Ischemia Stroke
Electro-acupuncture

Interventions

PROCEDURE

No Results Yet

NCT07102368 | RECRUITING

500 participants

A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-08-18
Completion:: 2029-01-15

Conditions

Inflammatory Bowel Disease
Colitis, Ulcerative
Crohn's Disease

No Results Yet

NCT07091981 | COMPLETED | NA

168 participants

Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-29
Completion:: 2025-11-19

Conditions

Postoperative Pain
Asymptomatic Apical Periodontitis

Interventions

DEVICE

No Results Yet

NCT07089043 | ACTIVE_NOT_RECRUITING | PHASE2

12 participants

A Study in Subjects With Neurogenic Orthostatic Hypotension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-09-12
Completion:: 2026-09-30

Conditions

Neurogenic Orthostatic Hypotension

Interventions

DRUG

No Results Yet

NCT07082920 | RECRUITING | PHASE1

140 participants

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-07
Completion:: 2027-11-30

Conditions

Prostatic Neoplasms

Interventions

DRUG

No Results Yet

NCT07076160 | COMPLETED | NA

74 participants

Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-24
Completion:: 2025-09-20

Conditions

Visual Acuity
Presbyopia

Interventions

DEVICE

No Results Yet

NCT07075185 | RECRUITING | PHASE1

70 participants

A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-16
Completion:: 2027-03-31

Conditions

Multiple Myeloma in Relapse
Myeloma Multiple
Multiple Myeloma Progression
Neoplasms by Histologic Type
Neoplasm
Hemostatic Disorders
Vascular Disorder
Paraproteinemias
Blood Protein Disorders
Hematologic Disease and Disorders
Lymphoproliferative Disorders
Immunoproliferative Disorders
Immune System Disease
Gene Therapy

Interventions

DRUG

No Results Yet

NCT07071623 | RECRUITING | PHASE3

4580 participants

A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-11-10
Completion:: 2027-10-18

Conditions

Human Immunodeficiency Virus (HIV)
HIV Pre-Exposure Prophylaxis

Interventions

DRUG

No Results Yet

NCT07070466 | RECRUITING | PHASE2

40 participants

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-10-10
Completion:: 2026-12-01

Conditions

Stomach Cancer Stage IV
Esophagus Cancer
Stomach Cancer

Interventions

DRUG

No Results Yet

NCT07070089 | RECRUITING | NA

90 participants

BosSTENT ImpLant to trEat debilitatiNg Pulse-synchronous Tinnitus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-02-01
Completion:: 2027-07-31

Conditions

Pulsatile Tinnitus
Venous Sinus Stenosis

Interventions

DEVICE

No Results Yet

NCT07060807 | RECRUITING | PHASE3

1000 participants

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-21
Completion:: 2033-07-14

Conditions

Breast Neoplasms

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07059065 | RECRUITING | NA

316 participants

FIBERGRAFT Aeridyan Posterolateral Fusion Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-08-15
Completion:: 2029-05-31

Conditions

Degenerative Spine Disease

Interventions

DEVICE

No Results Yet

NCT07057791 | RECRUITING | PHASE2

60 participants

Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-03-30
Completion:: 2027-12-31

Conditions

Extensive Stage Lung Small Cell Cancer

Interventions

DRUG

No Results Yet

NCT07054346 | RECRUITING | PHASE1

45 participants

Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-08
Completion:: 2027-04-30

Conditions

Prostate Cancer
Prostate Cancer (Diagnosis)
High-risk Prostate Cancer
Localized Prostate Carcinoma
Very High Risk Prostate Carcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07047716 | ACTIVE_NOT_RECRUITING | PHASE3

339 participants

Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-22
Completion:: 2028-09-30

Conditions

HIV Pre-exposure Prophylaxis

Interventions

DRUG

No Results Yet

NCT07038512 | WITHDRAWN | NA

0 participants

Evaluation of Hyivy Floora in Managing Interstitial Cystitis/Bladder Pain Syndrome/High-tone Pelvic Floor Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-08-31
Completion:: 2026-12-31

Conditions

Interstitial Cystitis/Painful Bladder Syndrome
Interstitial Cystitis, Chronic
High Tone Pelvic Floor Dysfunction

Interventions

DEVICE

No Results Yet

NCT07038343 | RECRUITING | PHASE1/PHASE2

480 participants

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-04
Completion:: 2030-06-30

Conditions

Solid Tumor Cancer
Locally Advanced
Metastatic Solid Tumors
Lung Cancers
Epithelial Tumor
Biliary Tract Cancer (BTC)
Urothelial Cancer
Nasopharyngeal Cancers

Interventions

DRUG

No Results Yet

NCT07035912 | NOT_YET_RECRUITING | NA

130 participants

Parent Implemented Oral Nutrition, Eating, and Esophageal Reflexes Reintegration Protocol: RCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2027-07-01
Completion:: 2031-06-30

Conditions

Deglutition Disorders in Infants
Chronic Tube Feeding in Hospitalized Infants

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07030712 | RECRUITING | PHASE1

67 participants

A Clinical Study of MK-8294 in Participants With Advanced Solid Tumors (MK-8294-001)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-23
Completion:: 2029-07-01

Conditions

Metastatic Neoplasm

Interventions

DRUG
OTHER

No Results Yet

NCT07030517 | ACTIVE_NOT_RECRUITING | PHASE4

75 participants

A Study to Assess Safety of Teclistamab in Indian Participants With Relapsed and Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-22
Completion:: 2026-11-03

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT07029399 | RECRUITING | PHASE1

361 participants

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-25
Completion:: 2027-07-31

Conditions

HR+ Breast Cancer
Triple Negative Breast Cancer (TNBC)
CCNE1 Amplified Advanced Solid Tumors
HR+ HER2- Breast Cancer

Interventions

DRUG

No Results Yet

NCT07016412 | COMPLETED | PHASE2

497 participants

A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-31
Completion:: 2026-08-17

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

DRUG

No Results Yet

NCT06997497 | RECRUITING | PHASE3

477 participants

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-16
Completion:: 2029-03-28

Conditions

Colon Adenocarcinoma
Rectal Adenocarcinoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06994884 | COMPLETED

16 participants

Patients' Experiences of Information After Total Knee Arthroplasty - A Qualitative Interview Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-09-19
Completion:: 2026-08-25

Conditions

Knee Osteoarthrosis
Total Knee Arthroplasty

No Results Yet

NCT06986161 | ACTIVE_NOT_RECRUITING | NA

33 participants

Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-04-14
Completion:: 2026-07-06

Conditions

Pre Diabetes

Interventions

OTHER

No Results Yet

NCT06982222 | WITHDRAWN | PHASE1

0 participants

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-10-01
Completion:: 2027-02-12

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Breast Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Bone
Metastatic Prostate Adenocarcinoma
Stage IV Lung Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8

Interventions

PROCEDURE
RADIATION

No Results Yet

NCT06980805 | ACTIVE_NOT_RECRUITING | PHASE2

56 participants

A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-19
Completion:: 2026-10-31

Conditions

Subacute Cutaneous Lupus Erythematosus
Chronic Cutaneous Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT06979596 | RECRUITING | PHASE2

250 participants

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-08-11
Completion:: 2027-11-04

Conditions

Malignant Neoplasm

Interventions

DRUG

No Results Yet

NCT06978686 | COMPLETED

210 participants

The Validity and Reliability of the Turkish Version of the BBAQ

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-20
Completion:: 2026-01-10

Conditions

Health Knowledge, Attitudes, Practice
Physical Inactivity

No Results Yet

NCT06975943 | COMPLETED | NA

48 participants

Comparison in Cervical Length and Prolongation of Gestation Age on Vaginal Progesterone Administration to Pregnant Women After the Acute Phase of Threatened Preterm Birth

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-01-01
Completion:: 2026-02-05

Conditions

Pregnant Women
Pregnancies at Increased Risk of Preterm Birth

Interventions

DRUG

No Results Yet

NCT06975059 | SUSPENDED | NA

40 participants

Novel Shoe Device NUSHU to Measure Gait Analysis in Parkinson's Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-30
Completion:: 2027-07-31

Conditions

Parkinson's Disease (PD)

Interventions

DEVICE

No Results Yet

NCT06971497 | RECRUITING

65 participants

Zimmer ActivBraid Rotator Cuff Repair (RCR) Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-08-11
Completion:: 2029-08-31

Conditions

Rotator Cuff Repair of the Shoulder

Interventions

DEVICE

No Results Yet

NCT06969521 | RECRUITING | NA

60 participants

Online Rotating Delivery of Perception/Production Enhanced Treatment for Rhotics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-10
Completion:: 2027-07-01

Conditions

Speech Sound Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06966700 | RECRUITING | PHASE3

2400 participants

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-30
Completion:: 2033-03-23

Conditions

Breast Neoplasms
Triple Negative Breast Neoplasms
HR Low-Positive/HER2-Negative Breast Neoplasms

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06952868 | RECRUITING | PHASE2

24 participants

Boron Neutron Capture Therapy With B10 L-BPA for Unresectable Recurrent Head and Neck Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-23
Completion:: 2026-08-31

Conditions

Head and Neck Cancer
Boron Neutron Capture Therapy

Interventions

DRUG

No Results Yet

NCT06952790 | RECRUITING | NA

25 participants

Fostering Oral Chemotherapy Understanding and Safety (FOCUS) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-10-02
Completion:: 2027-01-01

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06952504 | RECRUITING | PHASE3

1123 participants

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-22
Completion:: 2032-05-24

Conditions

Endometrial Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06951217 | RECRUITING | PHASE2

340 participants

An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-04-17
Completion:: 2031-12-31

Conditions

Progressive Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis (IPF)

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06942689 | RECRUITING | PHASE4

80 participants

Determination of the Optimal Volume of Liposomal Bupivacaine in Adductor Canal Block for Knee Joint Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-01
Completion:: 2027-12-31

Conditions

Optimal Volume of Liposomal Bupivacaine

Interventions

DRUG

No Results Yet

NCT06941844 | ACTIVE_NOT_RECRUITING | PHASE3

149 participants

A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-04-14
Completion:: 2026-05-20

Conditions

Major Depressive Disorder

Interventions

OTHER
DRUG

No Results Yet