Clinical Trials Updated in 2026

NCT06975059 | SUSPENDED | NA

40 participants

Novel Shoe Device NUSHU to Measure Gait Analysis in Parkinson's Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-30
Completion:: 2027-07-31

Conditions

Parkinson's Disease (PD)

Interventions

DEVICE

No Results Yet

NCT06971497 | RECRUITING

65 participants

Zimmer ActivBraid Rotator Cuff Repair (RCR) Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-08-11
Completion:: 2029-08-31

Conditions

Rotator Cuff Repair of the Shoulder

Interventions

DEVICE

No Results Yet

NCT06969521 | RECRUITING | NA

60 participants

Online Rotating Delivery of Perception/Production Enhanced Treatment for Rhotics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-10
Completion:: 2027-07-01

Conditions

Speech Sound Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06966700 | RECRUITING | PHASE3

2400 participants

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-30
Completion:: 2033-03-23

Conditions

Breast Neoplasms
Triple Negative Breast Neoplasms
HR Low-Positive/HER2-Negative Breast Neoplasms

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06952868 | RECRUITING | PHASE2

24 participants

Boron Neutron Capture Therapy With B10 L-BPA for Unresectable Recurrent Head and Neck Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-23
Completion:: 2026-08-31

Conditions

Head and Neck Cancer
Boron Neutron Capture Therapy

Interventions

DRUG

No Results Yet

NCT06952790 | RECRUITING | NA

25 participants

Fostering Oral Chemotherapy Understanding and Safety (FOCUS) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-10-02
Completion:: 2027-01-01

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06952504 | RECRUITING | PHASE3

1123 participants

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-22
Completion:: 2032-05-24

Conditions

Endometrial Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06951217 | RECRUITING | PHASE2

340 participants

An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-04-17
Completion:: 2031-12-31

Conditions

Progressive Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis (IPF)

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06942689 | RECRUITING | PHASE4

80 participants

Determination of the Optimal Volume of Liposomal Bupivacaine in Adductor Canal Block for Knee Joint Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-01
Completion:: 2027-12-31

Conditions

Optimal Volume of Liposomal Bupivacaine

Interventions

DRUG

No Results Yet

NCT06941844 | ACTIVE_NOT_RECRUITING | PHASE3

149 participants

A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-04-14
Completion:: 2026-05-20

Conditions

Major Depressive Disorder

Interventions

OTHER
DRUG

No Results Yet

NCT06941272 | RECRUITING | PHASE1/PHASE2

50 participants

A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-26
Completion:: 2030-12-30

Conditions

Malignant Neoplasm

Interventions

BIOLOGICAL

No Results Yet

NCT06937788 | TERMINATED

210 participants

Replication of the Heads Up Atopic Dermatitis Trial With Registry Data

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-08-02
Completion:: 2026-06-30

Conditions

Atopic Dermatitis

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06934226 | ACTIVE_NOT_RECRUITING | PHASE3

752 participants

A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-04-15
Completion:: 2025-11-17

Conditions

Plaque Psoriasis

Interventions

DRUG

No Results Yet

NCT06934044 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

A Study Evaluating the Pharmacokinetics, Safety, and Efficacy of Cevostamab in Chinese Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-13
Completion:: 2028-11-15

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06929949 | RECRUITING

90 participants

The Effect of Different Digestive Tract Reconstruction Methods on Postoperative Quality of Life After Proximal Gastrectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-11-25
Completion:: 2028-11-25

Conditions

Gastroesophageal Junction (GEJ) Cancer
Gastric Cancer

No Results Yet

NCT06926530 | NOT_YET_RECRUITING

240 participants

Herbs & Supplements in Breast Cancer Usage, Impact, and Personalized Approaches for Diverse Populations

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-10-31
Completion:: 2027-03-31

Conditions

Breast Cancer
Breast Cancer Stage I
Breast Cancer Stage II
Breast Cancer Stage III
Breast Carcinoma

Interventions

OTHER

No Results Yet

NCT06925737 | RECRUITING | PHASE3

1440 participants

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-13
Completion:: 2028-06-26

Conditions

Prostate Cancer
Prostatic Neoplasms

Interventions

DRUG

No Results Yet

NCT06925542 | RECRUITING | PHASE1

80 participants

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-10
Completion:: 2031-12-31

Conditions

SLE (Systemic Lupus)
Lupus Erythematosus, Systemic
Lupus Nephritis
Systemic Sclerosis
Inflammatory Myopathy, Idiopathic
Myositis
Diffuse Cutaneous Systemic Sclerosis

Interventions

BIOLOGICAL

No Results Yet

NCT06919965 | RECRUITING | PHASE3

220 participants

A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-09-10
Completion:: 2028-04-06

Conditions

Non-Muscle Invasive Bladder Neoplasms

Interventions

DRUG

No Results Yet

NCT06914609 | RECRUITING | PHASE3

158 participants

REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-10
Completion:: 2027-08-31

Conditions

Angelman Syndrome

Interventions

DRUG

No Results Yet

NCT06909565 | RECRUITING | PHASE4

6000 participants

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-23
Completion:: 2029-10-31

Conditions

Percutaneous Coronary Intervention
Peripheral Endovascular Intervention

Interventions

DRUG

No Results Yet

NCT06902480 | NOT_YET_RECRUITING | NA

24 participants

Dairy Choline Bioavailability

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-09-30
Completion:: 2027-12-31

Conditions

Post-menopausal Women
Post-menopausal Status

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06890910 | COMPLETED | NA

100 participants

A Nurse-Led Sleep Hygiene and Progressive Muscle Relaxation Intervention on Sleep Quality Among Obese Pregnant Women

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-01
Completion:: 2024-12-15

Conditions

Sleep Disorders
Obese Pregnant Women

Interventions

OTHER

No Results Yet

NCT06878820 | COMPLETED

425 participants

Nurses in the Lead - Nursing Leadership and Autonomy in Function Focused Care in Hospital

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-11-18
Completion:: 2025-10-11

Conditions

Nurse-Patient Relations
Implementation Research
Physical Inactivity
Physical Activities
ADL
Mobility and Independence
Leadership
Interprofessional Team Collaboration
Hospital Care

Interventions

BEHAVIORAL

No Results Yet

NCT06878404 | ACTIVE_NOT_RECRUITING | PHASE3

552 participants

A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-21
Completion:: 2026-05-25

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT06871098 | COMPLETED | NA

33 participants

Improving Mechanics and Confidence in the Hip Hinge

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-03
Completion:: 2026-08-25

Conditions

Hip Hinge
Hip and Knee Movement

Interventions

OTHER

No Results Yet

NCT06871085 | COMPLETED | NA

24 participants

Novel Sock Design on Ankle and Postural Stability

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-03
Completion:: 2026-08-25

Conditions

Ankle Stability
Postural Stability

Interventions

DEVICE

No Results Yet

NCT06860516 | RECRUITING

200 participants

HLA Demographics Study in Adults With Type 1 Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-06
Completion:: 2027-01-30

Conditions

Diabetes Mellitus, Type I

Interventions

OTHER

No Results Yet

NCT06856850 | ACTIVE_NOT_RECRUITING

230 participants

Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical Approaches

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-27
Completion:: 2027-02-28

Conditions

ALS (Amyotrophic Lateral Sclerosis)
FTD
Neuropathic
Psychiatric Disorders
Idiopathic Intracranial Hypertension
Frontotemporal Dementia (FTD)

No Results Yet

NCT06854250 | RECRUITING | PHASE2

104 participants

Prostate Cryoablation Combined With Metronomic Cyclophosphamide for Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-01
Completion:: 2029-03-01

Conditions

Metastatic Prostate Cancer

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06854237 | ACTIVE_NOT_RECRUITING

114 participants

Prevalence and Characteristics of Widespread Pain in People With Knee Osteoarthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-06
Completion:: 2025-02-28

Conditions

Knee Osteoarthritis
Widespread Chronic Pain

No Results Yet

NCT06852222 | RECRUITING | PHASE3

600 participants

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-04
Completion:: 2029-06-22

Conditions

Leukemia, Myeloid, Acute

Interventions

DRUG

No Results Yet

NCT06849570 | RECRUITING | NA

1200 participants

Assessment of the PEEP Responsiveness to Titrate End-expiratory Pressure and of the Need for Muscle Relaxation During Prone Positioning in Moderate-to-severe Acute Respiratory Distress Syndrome: A Master Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-11-05
Completion:: 2028-11-05

Conditions

Acute Respiratory Distress Syndrome (ARDS)
Intensive Care Units (ICUs)

Interventions

OTHER

No Results Yet

NCT06846658 | ACTIVE_NOT_RECRUITING

180 participants

Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-10-03
Completion:: 2027-04-30

Conditions

Parkinson Disease
MSA - Multiple System Atrophy
Lewy Body Dementia (LBD)
Neurodegenerative Disease
Healthy Subjects (HS)

No Results Yet

NCT06841354 | RECRUITING | PHASE3

1000 participants

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-16
Completion:: 2030-05-18

Conditions

Triple Negative Breast Neoplasms

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06830291 | RECRUITING

800 participants

Validation and Standardisation of a "Neuralix" Digital Ecological Battery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-11
Completion:: 2027-03-31

Conditions

Traumatic Brain Injuries

No Results Yet

NCT06825416 | COMPLETED | PHASE3

1165 participants

A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-16
Completion:: 2026-02-15

Conditions

Prevention of Arterial and Venous Thrombosis

Interventions

DRUG

No Results Yet

NCT06824467 | RECRUITING | PHASE3

770 participants

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-04-09
Completion:: 2029-04-27

Conditions

Ovarian Cancer
Fallopian Tube Cancer
Primary Peritoneal Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06819592 | RECRUITING | PHASE3

3300 participants

PRophylaxis Against Early VENTilator-associated Infections in Acute Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-10-30
Completion:: 2029-08-31

Conditions

All-cause Mortality
Quality of Life
Disability, Intellectual
Neurological Disorder
Acute Brain Injury
Ventilation, Mechanical
Intensive Care Medicine

Interventions

DRUG

No Results Yet

NCT06819189 | RECRUITING | PHASE1

50 participants

Role of Metal Ion Transporter ZIP8 in Alcohol-Related Behaviors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-06-10
Completion:: 2027-12-31

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet