Clinical Trials

NCT06524544 | RECRUITING | PHASE3

320 participants

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-12-02

Completion:

2030-12-31

Conditions

• Locally Advanced Urothelial Carcinoma
• Metastatic Urothelial Carcinoma
• Unresectable Urothelial Carcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT06510556 | RECRUITING | NA

250 participants

Feasibility Study of the FARAFLEX Mapping and PFA System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-02-17

Completion:

2027-02-15

Conditions

• Atrial Fibrillation
• Persistent Atrial Fibrillation
• Paroxysmal AF

Interventions

• DEVICE

No Results Yet

NCT06510205 | RECRUITING

6111 participants

The Study is an Observational Post-market Follow-up Program to Evaluate Long Term (5 Years) Safety of Mentor Breast Implants in Chinese Population

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2024-07-14

Completion:

2034-06-30

Conditions

• Breast Augmentation
• Mammaplasty

Interventions

• DEVICE

No Results Yet

NCT06507436 | COMPLETED | PHASE3

127 participants

The Phase III Clinical Study of Herombopag for the Treatment of Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-07-31

Completion:

2026-08-14

Conditions

• Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery

Interventions

• DRUG

No Results Yet

NCT06500884 | RECRUITING | PHASE2

210 participants

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-08-26

Completion:

2030-05-30

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06487000 | NOT_YET_RECRUITING | PHASE2

150 participants

Determine the Dose-dependent Efficacy and Safety of EC-18 in Patients With Moderate to Severe Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2027-05-31

Completion:

2027-10-31

Conditions

• Atopic Dermatitis

Interventions

• DRUG

No Results Yet

NCT06479824 | SUSPENDED | NA

60 participants

NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-08-19

Completion:

2026-10-01

Conditions

• Tricuspid Valve Insufficiency

Interventions

• DEVICE

No Results Yet

NCT06475937 | ACTIVE_NOT_RECRUITING | PHASE1

128 participants

A Study of DM001 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-24

Completion:

2027-01-31

Conditions

• Breast Neoplasms
• Carcinoma, Non-Small-Cell Lung
• Solid Carcinoma

Interventions

• DRUG

No Results Yet

NCT06473701 | ACTIVE_NOT_RECRUITING | PHASE3

30 participants

Reducing Breathlessness With Dronabinol in COPD Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-02-26

Completion:

2026-09-30

Conditions

• COPD
• Breathlessness
• Cannabis

Interventions

• DRUG

No Results Yet

NCT06472310 | RECRUITING

5000 participants

Clinical and demOgRaphic Features of Patients With Uncontrolled Severe Asthma in Russia (CORSAR)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2024-06-06

Completion:

2027-06-30

Conditions

• Severe Asthma

No Results Yet

NCT06470438 | ACTIVE_NOT_RECRUITING | PHASE1

58 participants

A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-05-28

Completion:

2027-10-29

Conditions

• Lymphoma, Non-Hodgkin
• Refractory B-Cell NHL
• Relapsed B-cell NHL

Interventions

• DRUG

No Results Yet

NCT06463158 | RECRUITING | NA

100 participants

The Impact of the Family Room App on Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-07-01

Completion:

2026-10-31

Conditions

• Well-Being, Psychological
• Engagement
• Satisfaction, Consumer

Interventions

• DEVICE

No Results Yet

NCT06462794 | RECRUITING | PHASE1

121 participants

First In Human Study of CX-801 in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-08-28

Completion:

2028-02-28

Conditions

• Solid Tumor, Adult

Interventions

• DRUG

No Results Yet

NCT06462547 | ACTIVE_NOT_RECRUITING | PHASE2

22 participants

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-06-19

Completion:

2026-10-31

Conditions

• Gene Mutations
• Pseudoxanthoma Elasticum
• Arterial Calcification
• Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency
• Autosomal Recessive Hypophosphatemic Rickets Type 2

Interventions

• DRUG

No Results Yet

NCT06460961 | COMPLETED | PHASE1

40 participants

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-07-14

Completion:

2026-07-29

Conditions

• Neoplasm Metastasis

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06459180 | ACTIVE_NOT_RECRUITING | PHASE3

686 participants

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-07-24

Completion:

2028-06-15

Conditions

• Cervical Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06455930 | COMPLETED | NA

10 participants

Stand-on Ride-on Power Mobility Devices for Children With Cerebral Palsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-06-01

Completion:

2025-12-31

Conditions

• Cerebral Palsy

Interventions

• DEVICE

Results Available

NCT06449651 | RECRUITING | PHASE3

39 participants

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-11-11

Completion:

2029-12-05

Conditions

• Thrombocytopenia, Neonatal Alloimmune

Interventions

• DRUG

No Results Yet

NCT06431815 | ACTIVE_NOT_RECRUITING

228 participants

ADVENT Post Approval Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2024-09-25

Completion:

2028-10-31

Conditions

• Paroxysmal Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT06428396 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-11-27

Completion:

2027-05-05

Conditions

• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06425991 | ACTIVE_NOT_RECRUITING | PHASE1

108 participants

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-06-07

Completion:

2025-06-03

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06423950 | RECRUITING

35 participants

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2024-05-01

Completion:

2027-04-30

Conditions

• Pediatric Cancer

Interventions

• OTHER

No Results Yet

NCT06423430 | RECRUITING | NA

100 participants

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-09-11

Completion:

2027-04-30

Conditions

• Treatment Resistant Depression

Interventions

• DEVICE

No Results Yet

NCT06422078 | RECRUITING

300 participants

A Non-interventional, Prospective Study With Benralizumab

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2024-07-25

Completion:

2027-12-31

Conditions

• Asthma, Bronchial

No Results Yet

NCT06420245 | ACTIVE_NOT_RECRUITING | NA

240 participants

Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-12-30

Completion:

2026-11-30

Conditions

• Diabetic Foot Ulcer

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT06408935 | ACTIVE_NOT_RECRUITING | PHASE3

120 participants

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-04-17

Completion:

2027-06-08

Conditions

• Crohn's Disease

Interventions

• DRUG

No Results Yet

NCT06395103 | RECRUITING | PHASE1/PHASE2

90 participants

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-08-16

Completion:

2029-03-31

Conditions

• B-cell Acute Lymphoblastic Leukemia
• Diffuse Large B-cell Lymphoma
• Burkitt Lymphoma
• Neuroblastoma
• Ewing Sarcoma

Interventions

• BIOLOGICAL

No Results Yet

NCT06393374 | RECRUITING | PHASE3

1530 participants

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-06-24

Completion:

2030-12-16

Conditions

• Triple-Negative Breast Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06385080 | RECRUITING | PHASE1/PHASE2

287 participants

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-04-22

Completion:

2032-12-27

Conditions

• Squamous Cell Carcinoma of Head and Neck

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06375044 | RECRUITING | PHASE1

130 participants

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-05-24

Completion:

2027-09-30

Conditions

• Relapsed or Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06373978 | RECRUITING | PHASE4

92 participants

NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-08-12

Completion:

2027-06-30

Conditions

• Elbow Pain
• Chronic Pain

Interventions

• DRUG
• OTHER

No Results Yet

NCT06373523 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

50 participants

MASLD in Primary Hypothyroidism and Efficacy of Dapaglifozin

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-01-15

Completion:

2026-06-15

Conditions

• Hepatic Steato-Fibrosis
• Non-Alcoholic Fatty Liver Disease

Interventions

• DRUG

No Results Yet

NCT06372964 | RECRUITING | PHASE3

384 participants

Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-05-14

Completion:

2031-10-31

Conditions

• Bipolar Depression

Interventions

• DRUG

No Results Yet

NCT06368401 | ACTIVE_NOT_RECRUITING | NA

10 participants

A First in Human Study for the Versa Device for Tricuspid Regurgitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-08-05

Completion:

2027-07-30

Conditions

• Tricuspid Regurgitation

Interventions

• DEVICE

No Results Yet

NCT06337318 | RECRUITING | PHASE3

600 participants

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-23

Completion:

2032-03-31

Conditions

• Classic Follicular Lymphoma
• Follicular Lymphoma With Unusual Cytological Features

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT06323980 | RECRUITING | NA

168 participants

INHANCE Stemless Reverse Shoulder IDE

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-03-04

Completion:

2027-11-10

Conditions

• Arthroplasty
• Replacement
• Shoulder

Interventions

• DEVICE

No Results Yet

NCT06323070 | RECRUITING | NA

80 participants

Effects of Watermelon or Low-fat Cookie Consumption on Wellness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-03-01

Completion:

2028-12-31

Conditions

• Overweight and Obesity

Interventions

• OTHER

No Results Yet

NCT06321705 | NO_LONGER_AVAILABLE

Safety and Efficacy of Continued CS1 Treatment of Patients With Pulmonary Arterial Hypertension

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-28

Conditions

• Pulmonary Arterial Hypertension

Interventions

• DRUG

No Results Yet

NCT06319820 | RECRUITING | PHASE3

641 participants

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-04-18

Completion:

2028-06-28

Conditions

• Non-Muscle Invasive Bladder Neoplasms

Interventions

• COMBINATION_PRODUCT
• DRUG

No Results Yet

NCT06312176 | RECRUITING | PHASE3

1200 participants

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-04-14

Completion:

2027-07-11

Conditions

• Breast Neoplasms

Interventions

• DRUG
• BIOLOGICAL

No Results Yet