Clinical Trials Updated in 2026

NCT06229210 | RECRUITING | PHASE3

300 participants

Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-01-25
Completion:: 2032-04-28

Conditions

Schizophrenia
Bipolar Disorder
Autism Spectrum Disorder

Interventions

DRUG

No Results Yet

NCT06228573 | RECRUITING | NA

68 participants

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-20
Completion:: 2026-11-15

Conditions

Knee Osteoarthritis

Interventions

PROCEDURE

No Results Yet

NCT06216327 | COMPLETED | NA

40 participants

Home Safety Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-08
Completion:: 2025-07-18

Conditions

Suicide
Firearm Injury
Overdose

Interventions

BEHAVIORAL

Results Available

NCT06211764 | ACTIVE_NOT_RECRUITING | PHASE3

272 participants

A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-09
Completion:: 2030-11-27

Conditions

Non-Muscle Invasive Bladder Neoplasms

Interventions

DRUG

No Results Yet

NCT06208150 | ACTIVE_NOT_RECRUITING | PHASE3

838 participants

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-01-22
Completion:: 2026-04-01

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06178614 | RECRUITING | PHASE1

200 participants

A Study of JNJ-87890387 for Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-14
Completion:: 2027-03-16

Conditions

Neoplasms
Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT06173765 | COMPLETED | NA

68 participants

Understanding Dose Related Effects of Strawberry

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-08-31
Completion:: 2023-03-30

Conditions

Pre-diabetes
Insulin Sensitivity
Insulin Resistance
Inflammation

Interventions

OTHER

No Results Yet

NCT06152809 | RECRUITING | PHASE1

10 participants

CIML NK Cells With Venetoclax for AML

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-02-20
Completion:: 2026-11-30

Conditions

Acute Myeloid Leukemia
Acute Myeloid Leukemia Recurrent
Leukemia
Leukemia, Myeloid

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06152042 | COMPLETED | PHASE2

37 participants

Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-28
Completion:: 2025-05-20

Conditions

Type 1 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT06141629 | COMPLETED | NA

30 participants

Benefits of a Bolus Calculator in Pediatric Patients on Multiple Daily Insulin Injections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-01-31
Completion:: 2015-09-30

Conditions

Poor Glycemic Control
Quality of Life

Interventions

DEVICE

No Results Yet

NCT06139406 | ACTIVE_NOT_RECRUITING | PHASE1

70 participants

A Study of JNJ-87801493 in Combination With T-Cell Engagers in Participants With B-cell Non-Hodgkin Lymphoid (NHLs) Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-06
Completion:: 2026-01-30

Conditions

Lymphoma, Non-Hodgkin

Interventions

DRUG

No Results Yet

NCT06137807 | ACTIVE_NOT_RECRUITING | NA

50 participants

TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-23
Completion:: 2026-09-30

Conditions

Tricuspid Regurgitation
Tricuspid Valve Disease

Interventions

DEVICE

No Results Yet

NCT06136624 | RECRUITING | PHASE3

1310 participants

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-31
Completion:: 2028-08-02

Conditions

Prostate Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT06132958 | ACTIVE_NOT_RECRUITING | PHASE3

710 participants

Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-06
Completion:: 2028-01-10

Conditions

Endometrial Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06120283 | RECRUITING | PHASE1

433 participants

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-01
Completion:: 2029-12-31

Conditions

Advanced Solid Tumor
Advanced Breast Cancer
Metastatic Breast Cancer
Hormone-receptor-positive Breast Cancer
Hormone Receptor Positive Breast Carcinoma
Hormone Receptor Positive Malignant Neoplasm of Breast
HER2-negative Breast Cancer
Hormone Receptor Positive HER-2 Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT06120140 | ACTIVE_NOT_RECRUITING | PHASE2

305 participants

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-02-16
Completion:: 2027-05-31

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG
OTHER

No Results Yet

NCT06116786 | ACTIVE_NOT_RECRUITING | PHASE1

67 participants

A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-11-27
Completion:: 2027-04-14

Conditions

Carcinoma, Non-small-Cell Lung

Interventions

DRUG
RADIATION

No Results Yet

NCT06096870 | RECRUITING | PHASE2

65 participants

Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-22
Completion:: 2028-12-31

Conditions

Prostate Cancer
Recurrent Prostate Cancer
PET Positive

Interventions

DRUG

No Results Yet

NCT06096337 | ACTIVE_NOT_RECRUITING | NA

484 participants

Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-28
Completion:: 2026-02-04

Conditions

Persistent Atrial Fibrillation

Interventions

DEVICE
DRUG

No Results Yet

NCT06095115 | ACTIVE_NOT_RECRUITING | PHASE3

684 participants

A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-10-12
Completion:: 2024-07-29

Conditions

Plaque Psoriasis

Interventions

DRUG

Results Available

NCT06095102 | ACTIVE_NOT_RECRUITING | PHASE3

311 participants

A Study of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas (Scalp, Genital, and/or Palms of the Hands and the Soles of the Feet)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-10-12
Completion:: 2024-06-19

Conditions

Plaque Psoriasis

Interventions

DRUG

Results Available

NCT06095089 | RECRUITING | PHASE1

355 participants

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-11-01
Completion:: 2027-06-21

Conditions

Prostatic Neoplasms

Interventions

DRUG

No Results Yet

NCT06088199 | COMPLETED | PHASE3

51 participants

A Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-10-24
Completion:: 2026-08-12

Conditions

Plaque Psoriasis

Interventions

DRUG

No Results Yet

NCT06071130 | NOT_YET_RECRUITING | NA

240 participants

Connecting Socioemotional Aspects of Exercise to Improvements in Physical Health Among Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-08-21
Completion:: 2027-12-31

Conditions

Motivation
Aging
Health Behavior
Emotions
Social Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT06069544 | COMPLETED | PHASE1/PHASE2

163 participants

A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-11-13
Completion:: 2025-05-28

Conditions

Malaria

Interventions

BIOLOGICAL
OTHER

Results Available

NCT06068985 | ACTIVE_NOT_RECRUITING | PHASE2

63 participants

Classifying for HER2 Dependence to De-Escalate Neoadjuvant Chemotherapy in Patients With HER2+ Early Breast Cancer Undergoing HER2 Double-Blockade

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-05
Completion:: 2027-04-30

Conditions

Breast Cancer
HER2-positive Breast Cancer

Interventions

DRUG

No Results Yet

NCT06062342 | RECRUITING | NA

20400 participants

Five Point Initiative: A Bundled Implementation Strategy to Address the HIV Epidemic in Black Communities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-02-02
Completion:: 2028-12-01

Conditions

Hiv

Interventions

BEHAVIORAL

No Results Yet

NCT06062238 | ACTIVE_NOT_RECRUITING | PHASE3

20080 participants

Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-03-05
Completion:: 2028-04-30

Conditions

Tuberculosis

Interventions

BIOLOGICAL

No Results Yet

NCT06043557 | ENROLLING_BY_INVITATION | NA

50 participants

Patient Satisfaction and Reflection on Drain Placement

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-01-01
Completion:: 2026-12-31

Conditions

Abdominoplasty
Panniculectomy

Interventions

PROCEDURE

No Results Yet

NCT06004804 | RECRUITING | NA

216 participants

Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-10-01
Completion:: 2027-09-30

Conditions

Chronic Musculoskeletal Pain

Interventions

BEHAVIORAL

No Results Yet

NCT05999604 | ACTIVE_NOT_RECRUITING | PHASE3

244 participants

Impact of Annual Versus Biannual Infusions of Ocrelizumab in Patients With Active MS,After 2 Years of Initial Treatment, on Freedom From Radiological Disease Activity at Two Years: a Multicenter Randomized Controlled Non-inferiority Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-11-09
Completion:: 2028-05-31

Conditions

Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT05988931 | ACTIVE_NOT_RECRUITING | NA

1406 participants

Technology Interventions for Youth Alcohol Use

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-10-25
Completion:: 2027-09-30

Conditions

Alcohol Drinking

Interventions

BEHAVIORAL

No Results Yet

NCT05987241 | RECRUITING | PHASE2/PHASE3

992 participants

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-02-02
Completion:: 2030-09-02

Conditions

Muscle Invasive Bladder Urothelial Carcinoma
Muscle Invasive Renal Pelvis Urothelial Carcinoma
Muscle Invasive Ureter Urothelial Carcinoma
Muscle Invasive Urethral Urothelial Carcinoma
Stage II Bladder Urothelial Carcinoma AJCC v6 and v7
Stage III Bladder Urothelial Carcinoma AJCC v6 and v7
Stage IV Bladder Urothelial Carcinoma AJCC v7

Interventions

PROCEDURE
OTHER
BIOLOGICAL

No Results Yet

NCT05986864 | RECRUITING | PHASE1/PHASE2

68 participants

Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-02-23
Completion:: 2027-01-31

Conditions

Neovascular Age-related Macular Degeneration

Interventions

GENETIC

No Results Yet

NCT05979337 | COMPLETED | NA

180 participants

Brief Interventions in Chronic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-10-11
Completion:: 2026-03-04

Conditions

Chronic Migraine

Interventions

BEHAVIORAL

No Results Yet

NCT05963074 | ACTIVE_NOT_RECRUITING | PHASE2

333 participants

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-05-30
Completion:: 2027-12-15

Conditions

Leukemia, Lymphocytic, Chronic, B-Cell
Small Lymphocytic Lymphoma

Interventions

DRUG

No Results Yet

NCT05957536 | RECRUITING | PHASE1

128 participants

A Study of D3L-001 as Monotherapy in Subjects With HER2-Positive Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-09-19
Completion:: 2028-12-19

Conditions

HER-2 Positive Advanced Solid Tumors

Interventions

BIOLOGICAL

No Results Yet

NCT05957276 | COMPLETED

886 participants

Global Patient Registry of Inherited Retinal Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-08-31
Completion:: 2026-07-02

Conditions

Inherited Retinal Diseases

Interventions

OTHER

No Results Yet

NCT05956158 | ACTIVE_NOT_RECRUITING | NA

83 participants

RISE: A Remote Study of Insomnia Treatment in Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-11-28
Completion:: 2026-09-15

Conditions

Insomnia
Crohn Disease

Interventions

BEHAVIORAL

No Results Yet

NCT05949606 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

95 participants

A Study of SI-B001+SI-B003± Chemotherapy in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-10-30
Completion:: 2026-12-31

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet