Clinical Trials Updated in 2026

NCT06462794 | RECRUITING | PHASE1

121 participants

First In Human Study of CX-801 in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-28
Completion:: 2028-02-28

Conditions

Solid Tumor, Adult

Interventions

DRUG

No Results Yet

NCT06462547 | ACTIVE_NOT_RECRUITING | PHASE2

22 participants

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-19
Completion:: 2026-10-31

Conditions

Gene Mutations
Pseudoxanthoma Elasticum
Arterial Calcification
Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency
Autosomal Recessive Hypophosphatemic Rickets Type 2

Interventions

DRUG

No Results Yet

NCT06460961 | COMPLETED | PHASE1

40 participants

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-14
Completion:: 2026-07-29

Conditions

Neoplasm Metastasis

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06459180 | ACTIVE_NOT_RECRUITING | PHASE3

686 participants

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-24
Completion:: 2028-06-15

Conditions

Cervical Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06455930 | COMPLETED | NA

10 participants

Stand-on Ride-on Power Mobility Devices for Children With Cerebral Palsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-01
Completion:: 2025-12-31

Conditions

Cerebral Palsy

Interventions

DEVICE

Results Available

NCT06449651 | RECRUITING | PHASE3

39 participants

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-11-11
Completion:: 2029-12-05

Conditions

Thrombocytopenia, Neonatal Alloimmune

Interventions

DRUG

No Results Yet

NCT06431815 | ACTIVE_NOT_RECRUITING

228 participants

ADVENT Post Approval Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-25
Completion:: 2028-10-31

Conditions

Paroxysmal Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT06428396 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-11-27
Completion:: 2027-05-05

Conditions

Metastatic Breast Cancer

Interventions

DRUG

No Results Yet

NCT06425991 | ACTIVE_NOT_RECRUITING | PHASE1

108 participants

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-07
Completion:: 2025-06-03

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06423950 | RECRUITING

35 participants

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-05-01
Completion:: 2027-04-30

Conditions

Pediatric Cancer

Interventions

OTHER

No Results Yet

NCT06423430 | RECRUITING | NA

100 participants

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-11
Completion:: 2027-04-30

Conditions

Treatment Resistant Depression

Interventions

DEVICE

No Results Yet

NCT06422806 | RECRUITING | PHASE3

365 participants

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-11
Completion:: 2032-04-18

Conditions

Metastatic Dedifferentiated Liposarcoma
Metastatic Undifferentiated Pleomorphic Sarcoma
Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Unresectable Dedifferentiated Liposarcoma
Unresectable Undifferentiated Pleomorphic Sarcoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT06422078 | RECRUITING

300 participants

A Non-interventional, Prospective Study With Benralizumab

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-25
Completion:: 2027-12-31

Conditions

Asthma, Bronchial

No Results Yet

NCT06420245 | ACTIVE_NOT_RECRUITING | NA

240 participants

Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-12-30
Completion:: 2026-11-30

Conditions

Diabetic Foot Ulcer

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06408935 | ACTIVE_NOT_RECRUITING | PHASE3

120 participants

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-17
Completion:: 2027-06-08

Conditions

Crohn's Disease

Interventions

DRUG

No Results Yet

NCT06395103 | RECRUITING | PHASE1/PHASE2

90 participants

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-16
Completion:: 2029-03-31

Conditions

B-cell Acute Lymphoblastic Leukemia
Diffuse Large B-cell Lymphoma
Burkitt Lymphoma
Neuroblastoma
Ewing Sarcoma

Interventions

BIOLOGICAL

No Results Yet

NCT06393374 | RECRUITING | PHASE3

1530 participants

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-24
Completion:: 2030-12-16

Conditions

Triple-Negative Breast Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06385080 | RECRUITING | PHASE1/PHASE2

287 participants

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-22
Completion:: 2032-12-27

Conditions

Squamous Cell Carcinoma of Head and Neck

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06375044 | RECRUITING | PHASE1

130 participants

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-05-24
Completion:: 2027-09-30

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06373978 | RECRUITING | PHASE4

92 participants

NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-12
Completion:: 2027-06-30

Conditions

Elbow Pain
Chronic Pain

Interventions

DRUG
OTHER

No Results Yet

NCT06373523 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

50 participants

MASLD in Primary Hypothyroidism and Efficacy of Dapaglifozin

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-01-15
Completion:: 2026-06-15

Conditions

Hepatic Steato-Fibrosis
Non-Alcoholic Fatty Liver Disease

Interventions

DRUG

No Results Yet

NCT06372964 | RECRUITING | PHASE3

384 participants

Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-05-14
Completion:: 2031-10-31

Conditions

Bipolar Depression

Interventions

DRUG

No Results Yet

NCT06368401 | ACTIVE_NOT_RECRUITING | NA

10 participants

A First in Human Study for the Versa Device for Tricuspid Regurgitation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-05
Completion:: 2027-07-30

Conditions

Tricuspid Regurgitation

Interventions

DEVICE

No Results Yet

NCT06337318 | RECRUITING | PHASE3

600 participants

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-23
Completion:: 2032-03-31

Conditions

Classic Follicular Lymphoma
Follicular Lymphoma With Unusual Cytological Features

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT06323980 | RECRUITING | NA

168 participants

INHANCE Stemless Reverse Shoulder IDE

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-04
Completion:: 2027-11-10

Conditions

Arthroplasty
Replacement
Shoulder

Interventions

DEVICE

No Results Yet

NCT06323070 | RECRUITING | NA

80 participants

Effects of Watermelon or Low-fat Cookie Consumption on Wellness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-03-01
Completion:: 2028-12-31

Conditions

Overweight and Obesity

Interventions

OTHER

No Results Yet

NCT06321705 | NO_LONGER_AVAILABLE

Safety and Efficacy of Continued CS1 Treatment of Patients With Pulmonary Arterial Hypertension

Study Type:: EXPANDED_ACCESS
Last Updated:: 2026-08-28

Conditions

Pulmonary Arterial Hypertension

Interventions

DRUG

No Results Yet

NCT06319820 | RECRUITING | PHASE3

641 participants

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-18
Completion:: 2028-06-28

Conditions

Non-Muscle Invasive Bladder Neoplasms

Interventions

COMBINATION_PRODUCT
DRUG

No Results Yet

NCT06312176 | RECRUITING | PHASE3

1200 participants

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-14
Completion:: 2027-07-11

Conditions

Breast Neoplasms

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06311578 | RECRUITING | PHASE1

126 participants

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-10
Completion:: 2028-11-08

Conditions

Neoplasms

Interventions

DRUG

No Results Yet

NCT06302439 | ACTIVE_NOT_RECRUITING

54 participants

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-25
Completion:: 2026-08-28

Conditions

Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency
ATP-Binding Cassette Subfamily C Member 6 Deficiency

Interventions

OTHER

No Results Yet

NCT06302348 | RECRUITING | PHASE3

56 participants

A Study of Sepiapterin in Participants With Phenylketonuria (PKU)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-03-04
Completion:: 2031-02-28

Conditions

Phenylketonuria

Interventions

DRUG

No Results Yet

NCT06299540 | RECRUITING

180 participants

Benefits of Individual Physical Activity Intervention on Health-related Quality of Life in Participants With Chronic Lymphocytic Leukemia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-05-27
Completion:: 2026-09-30

Conditions

Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

BEHAVIORAL
DRUG

No Results Yet

NCT06285318 | RECRUITING

900 participants

A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-18
Completion:: 2026-08-30

Conditions

Relapsed/Refractory Multiple Myeloma (RRMM)

Interventions

OTHER

No Results Yet

NCT06283472 | COMPLETED | NA

21 participants

Enhancing Prospective Thinking in Early Recovery (BEAM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-17
Completion:: 2025-01-08

Conditions

Alcohol Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06283446 | COMPLETED | NA

58 participants

Enhancing Prospective Thinking in Early Recovery (NERF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-08-31
Completion:: 2026-05-26

Conditions

Alcohol Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06274359 | TERMINATED | NA

398 participants

Digital Storytelling to Reduce Pediatric Influenza Vaccination Disparities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-02
Completion:: 2025-03-31

Conditions

Influenza

Interventions

BEHAVIORAL

Results Available

NCT06261502 | RECRUITING | PHASE2

40 participants

Effect of CANnabidiol on Anxiety and GABAergic Function in Individuals With Fragile-X Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-09-01
Completion:: 2028-07-01

Conditions

Fragile X Syndrome

Interventions

DRUG

No Results Yet

NCT06260163 | ACTIVE_NOT_RECRUITING | PHASE3

112 participants

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-01-19
Completion:: 2027-02-10

Conditions

Colitis, Ulcerative

Interventions

DRUG

No Results Yet

NCT06239701 | ACTIVE_NOT_RECRUITING | NA

56 participants

Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use - RCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-01-22
Completion:: 2026-03-31

Conditions

Pregnancy

Interventions

BEHAVIORAL

No Results Yet