Clinical Trials Updated in 2026

NCT05624450 | RECRUITING | PHASE3

3527 participants

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-12-13
Completion:: 2027-11-04

Conditions

Viral Lung Infection and Acute Respiratory Failure

Interventions

DRUG

No Results Yet

NCT05617014 | ENROLLING_BY_INVITATION

1500 participants

Alzheimer's Disease Neuroimaging Initiative 4

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-06-09
Completion:: 2027-07-31

Conditions

Mild Cognitive Impairment
Alzheimer Disease
Dementia

Interventions

RADIATION

No Results Yet

NCT05610787 | ENROLLING_BY_INVITATION | NA

40 participants

EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-11-14
Completion:: 2023-11-10

Conditions

Heart Failure
Transplant; Failure, Heart
Congenital Heart Disease

Interventions

DEVICE

No Results Yet

NCT05605353 | ACTIVE_NOT_RECRUITING

450 participants

Exploiting the Gut Microbiota and Its Metabolites in Pelvic Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-03-01
Completion:: 2025-08-05

Conditions

Pelvic Neoplasm

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05597033 | COMPLETED | NA

68 participants

Exercise and Vascular Function in Postmenopausal Females With Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-01-09
Completion:: 2025-06-24

Conditions

Hypertension

Interventions

BEHAVIORAL

Results Available

NCT05596799 | COMPLETED | NA

70 participants

Facing Eating Disorder Fears for Anorexia Nervosa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-12-08
Completion:: 2026-04-27

Conditions

Eating Disorders
Anorexia Nervosa
Anorexia Nervosa in Remission

Interventions

BEHAVIORAL

No Results Yet

NCT05596331 | RECRUITING | NA

460 participants

Social Information Processing in Children: an ocUlo-pupillometric Tool for Standard Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-01-03
Completion:: 2026-01-03

Conditions

Autism Spectrum Disorder

Interventions

OTHER

No Results Yet

NCT05588141 | RECRUITING | PHASE1/PHASE2

96 participants

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-05-16
Completion:: 2028-08-01

Conditions

Brain Tumor
Cancer

Interventions

DRUG

No Results Yet

NCT05567185 | ACTIVE_NOT_RECRUITING | PHASE1

5 participants

A Study of Erdafitinib Intravesical Delivery System in Japanese Participants With Bladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-03-03
Completion:: 2025-03-11

Conditions

Urinary Bladder Neoplasms
Receptors, Fibroblast Growth Factor

Interventions

DRUG

No Results Yet

NCT05565599 | ACTIVE_NOT_RECRUITING | NA

58 participants

An Early Feasibility Study Evaluating the Safety and Efficacy of the Laminar Left Atrial Appendage Closure System in Subjects With Non-Valvular Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-10-21
Completion:: 2024-08-07

Conditions

Non-valvular Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT05560932 | COMPLETED | NA

50 participants

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-03-06
Completion:: 2024-01-04

Conditions

HIV
Alcohol Use

Interventions

BEHAVIORAL

Results Available

NCT05552222 | RECRUITING | PHASE3

1590 participants

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-10-25
Completion:: 2031-04-30

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05545306 | RECRUITING | NA

120 participants

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-06-06
Completion:: 2027-02-02

Conditions

Obesity
Normal Physiology
Healthy Volunteers

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05543512 | COMPLETED | NA

68 participants

The Immune Directed Individualized Elimination Therapy (iDIET) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-10-24
Completion:: 2025-12-18

Conditions

Eosinophilic Esophagitis
EoE

Interventions

DEVICE
OTHER

Results Available

NCT05531565 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

450 participants

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-09-13
Completion:: 2026-10-20

Conditions

Subacute Cutaneous Lupus Erythematosus
Chronic Cutaneous Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT05531396 | COMPLETED | NA

57 participants

Agility Training on Physical Performance, Cognitive Function and Brain Activities in Elderly

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-09-28
Completion:: 2025-06-04

Conditions

Elderly
Healthy

Interventions

OTHER

No Results Yet

NCT05529654 | COMPLETED | NA

100 participants

IMpella-Protected cArdiaC Surgery Trial (IMPACT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-09-21
Completion:: 2025-11-04

Conditions

Left Ventricular Dysfunction

Interventions

DEVICE

No Results Yet

NCT05528510 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-09-13
Completion:: 2024-04-02

Conditions

Colitis, Ulcerative

Interventions

DRUG
OTHER

Results Available

NCT05512390 | ACTIVE_NOT_RECRUITING | PHASE1

39 participants

A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-04-26
Completion:: 2027-02-28

Conditions

Diffuse Large B-Cell Lymphoma
Chronic Lymphocytic Leukemia
Follicular Lymphoma

Interventions

DRUG

No Results Yet

NCT05498428 | RECRUITING | PHASE2

520 participants

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-11-11
Completion:: 2027-08-17

Conditions

Carcinoma, Non-small-Cell Lung

Interventions

DRUG

No Results Yet

NCT05493904 | ACTIVE_NOT_RECRUITING | NA

320 participants

PREcise Percutaneous Coronary Intervention for Stent OptimizatION in Treatment of COMPLEX Lesion (PRECISION-COMPLEX)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-11-01
Completion:: 2024-12-05

Conditions

Coronary Artery Disease
Angina Pectoris

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT05488314 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

57 participants

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-12-13
Completion:: 2027-04-28

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

No Results Yet

NCT05480995 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-01-17
Completion:: 2026-08-31

Conditions

Endometriosis

Interventions

DRUG

No Results Yet

NCT05455320 | ACTIVE_NOT_RECRUITING | PHASE3

864 participants

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-10-13
Completion:: 2027-07-30

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05454787 | RECRUITING

300 participants

Ondexxya for Intravenous Injection 200mg Drug Use Result Investigation (All Case Investigation)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-06-02
Completion:: 2026-10-31

Conditions

Life Threatening Bleeding
Factor Xa Inhibitor

No Results Yet

NCT05453903 | ACTIVE_NOT_RECRUITING | PHASE1

196 participants

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-10-04
Completion:: 2026-10-30

Conditions

Leukemia, Myeloid, Acute

Interventions

DRUG

No Results Yet

NCT05445908 | COMPLETED | PHASE2

184 participants

SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-08-17
Completion:: 2026-07-31

Conditions

Triple-negative Breast Cancer and HR+/HER2- BC

Interventions

DRUG

No Results Yet

NCT05438043 | ACTIVE_NOT_RECRUITING | PHASE3

213 participants

A Study of Daratumumab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-12-15
Completion:: 2029-01-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05424822 | ACTIVE_NOT_RECRUITING | PHASE1

167 participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-08-18
Completion:: 2025-10-31

Conditions

Lymphoma, Non-Hodgkin
Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

DRUG

No Results Yet

NCT05423756 | COMPLETED | NA

118562 participants

INSPIRE Trial for Skin and Soft Tissue Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-01-01
Completion:: 2024-05-09

Conditions

Skin and Soft Tissue (SST) Infection

Interventions

OTHER

Results Available

NCT05421858 | RECRUITING | PHASE3

450 participants

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-12-11
Completion:: 2028-01-30

Conditions

Candidemia
Candidiasis, Invasive

Interventions

DRUG

No Results Yet

NCT05421663 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

166 participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-08-12
Completion:: 2041-07-30

Conditions

Lymphoma, Non-Hodgkin
Lymphoma, B-Cell
Lymphoma, Large B-Cell, Diffuse

Interventions

BIOLOGICAL

No Results Yet

NCT05416255 | COMPLETED | NA

80 participants

Measuring Synovial Fluid Components

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-04-19
Completion:: 2026-04-20

Conditions

Knee Osteoarthritis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05403476 | TERMINATED | PHASE2

4 participants

A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-08-16
Completion:: 2024-10-05

Conditions

Male Idiopathic Infertility

Interventions

DRUG

Results Available

NCT05384158 | RECRUITING | NA

252 participants

Valuation in Depressed Mood, Anhedonia, and Anxiety

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-08-01
Completion:: 2027-07-31

Conditions

Neurobehavioral Components of Reward and Loss Valuation

Interventions

BEHAVIORAL

No Results Yet

NCT05379595 | RECRUITING | PHASE1/PHASE2

225 participants

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-07-29
Completion:: 2027-04-27

Conditions

Advanced or Metastatic Colorectal Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT05359822 | NOT_YET_RECRUITING | NA

7000 participants

Investigating the Impact of a Patient-directed Coronary Artery Calcium Score Report

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2027-01-01
Completion:: 2027-05-31

Conditions

Cardiac Computed Tomography for Calicum Scoring

Interventions

OTHER

No Results Yet

NCT05352919 | ENROLLING_BY_INVITATION | PHASE3

864 participants

An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-06-10
Completion:: 2030-03-29

Conditions

Systemic Lupus Erythematosus (SLE)

Interventions

DRUG

No Results Yet

NCT05347095 | ACTIVE_NOT_RECRUITING | PHASE3

288 participants

A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-09-27
Completion:: 2027-03-25

Conditions

Fistulizing Crohns Disease
Perianal Crohns Disease

Interventions

DRUG

No Results Yet

NCT05344833 | RECRUITING | PHASE2

50 participants

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-01-05
Completion:: 2030-12-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet