Clinical Trials

NCT04802590 | ACTIVE_NOT_RECRUITING | PHASE2

210 participants

Study of Ibrutinib + CD20 Antibody and Venetoclax in Patients With Untreated Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-01-24

Completion:

2025-05-27

Conditions

• Mantle Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT04799301 | RECRUITING | PHASE1

60 participants

Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-02-23

Completion:

2028-01-01

Conditions

• Diet Therapy
• Healthy Volunteers

Interventions

• BEHAVIORAL

No Results Yet

NCT04794101 | ACTIVE_NOT_RECRUITING | PHASE3

97 participants

Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-12-04

Completion:

2029-09-20

Conditions

• X-Linked Retinitis Pigmentosa

Interventions

• BIOLOGICAL

No Results Yet

NCT04793217 | COMPLETED | NA

350 participants

A Randomized Trial of ImpACT+, a Coping Intervention for HIV Infected Women With Sexual Trauma in South Africa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-02-18

Completion:

2025-07-03

Conditions

• HIV
• Trauma Exposure

Interventions

• BEHAVIORAL

Results Available

NCT04787341 | COMPLETED | PHASE2

213 participants

PAnitumumab REchallenge Followed by REgorafenib Versus the Reverse Sequence

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-12-15

Completion:

2025-08-07

Conditions

• Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT04785677 | COMPLETED | NA

403 participants

Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-02-09

Completion:

2023-05-30

Conditions

• Stress Disorders, Traumatic
• Stress Disorders, Traumatic, Acute
• Depressive Symptoms
• Anxiety
• Substance Use
• Aggression
• Coping Skills
• Impulsive Behavior
• Housing Problems
• Recidivism
• Stress
• Occupational Stress
• Psychological Distress

Interventions

• BEHAVIORAL

Results Available

NCT04773548 | COMPLETED | NA

12 participants

Feasibility and Safety of a Virtual-Reality Based Job Interview Training Tool in Teenagers With High-Functioning Autism

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2018-10-24

Completion:

2020-10-24

Conditions

• Autism Spectrum Disorder

Interventions

• OTHER

No Results Yet

NCT04750798 | RECRUITING

8000 participants

An Observational Post-marketing Study Using Commercially Approved Biosense Webster (BWI) Medical Devices for the Treatment of Participants With Cardiac Arrhythmias

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-02-22

Completion:

2036-12-31

Conditions

• Arrhythmias, Cardiac

Interventions

• DEVICE

No Results Yet

NCT04747314 | COMPLETED | PHASE2

308 participants

Treating Negative Affect in Low Back Pain Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-03-31

Completion:

2024-11-04

Conditions

• Chronic Low Back Pain
• Negative Affectivity

Interventions

• DRUG
• OTHER

Results Available

NCT04722263 | RECRUITING | NA

15 participants

Radiotherapy for Keloids

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-12-01

Completion:

2027-04-30

Conditions

• Keloid

Interventions

• RADIATION

No Results Yet

NCT04722146 | ACTIVE_NOT_RECRUITING | PHASE1

140 participants

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-03-12

Completion:

2025-10-03

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT04721691 | COMPLETED | PHASE1

16 participants

Efficacy of Epidiolex in Patients With Electrical Status Epilepticus of Sleep (ESES).

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-03-10

Completion:

2024-01-17

Conditions

• Electrical Status Epilepticus of Slow-Wave Sleep

Interventions

• DRUG
• OTHER

No Results Yet

NCT04677816 | RECRUITING | PHASE2

50 participants

Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-10-22

Completion:

2026-12-31

Conditions

• Triple Negative Breast Cancer
• Vitamin D Deficiency
• Invasive Breast Cancer

Interventions

• DRUG
• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT04662580 | ACTIVE_NOT_RECRUITING | PHASE1

183 participants

ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-05-03

Completion:

2026-12-31

Conditions

• Metastatic Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04662372 | COMPLETED

40 participants

Functional Neurological Disorders in Patients Admitted in Stroke Units

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-03-05

Completion:

2025-10-31

Conditions

• Functional Neurological Disorders

Interventions

• OTHER

No Results Yet

NCT04658862 | ACTIVE_NOT_RECRUITING | PHASE3

518 participants

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-12-07

Completion:

2026-12-30

Conditions

• Urinary Bladder Neoplasms

Interventions

• BIOLOGICAL
• DRUG
• RADIATION

No Results Yet

NCT04644770 | ACTIVE_NOT_RECRUITING | PHASE1

144 participants

A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-11-12

Completion:

2026-12-08

Conditions

• Prostatic Neoplasms
• Adenocarcinoma

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04640623 | ACTIVE_NOT_RECRUITING | PHASE2

220 participants

A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-12-18

Completion:

2025-07-03

Conditions

• Urinary Bladder Neoplasms

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04639830 | RECRUITING

244 participants

Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-11-09

Completion:

2027-04-15

Conditions

• Healthy Children
• Children With Neurodevelopmental Disorders
• Children With Neuropsychiatric Disorders
• Children With Behavioral Syndromes

No Results Yet

NCT04634552 | RECRUITING | PHASE2

510 participants

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-02-01

Completion:

2027-06-30

Conditions

• Hematological Malignancies

Interventions

• DRUG

No Results Yet

NCT04616560 | RECRUITING | PHASE2

55 participants

Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-03-08

Completion:

2027-12-31

Conditions

• Desmoplastic Small Round Cell Tumor
• Osteosarcoma
• Recurrent Desmoplastic Small Round Cell Tumor
• Recurrent Kidney Wilms Tumor
• Recurrent Osteosarcoma
• Refractory Desmoplastic Small Round Cell Tumor
• Refractory Wilms Tumor
• Wilms Tumor

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT04609072 | RECRUITING

200000 participants

Connect for Cancer Prevention Study (Connect)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-07-26

Completion:

2070-12-31

Conditions

• Cancer
• General Research Use

No Results Yet

NCT04606381 | ACTIVE_NOT_RECRUITING | PHASE1

158 participants

A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-11-10

Completion:

2024-07-11

Conditions

• Neoplasms

Interventions

• DRUG

No Results Yet

NCT04585958 | RECRUITING | PHASE1

55 participants

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-05-21

Completion:

2026-12-31

Conditions

• Metastatic Malignant Solid Neoplasm
• Platinum-Resistant Ovarian High Grade Serous Adenocarcinoma
• Unresectable Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT04577833 | ACTIVE_NOT_RECRUITING | PHASE1

136 participants

A Study of Comparative Formulations of Niraparib and Abiraterone Acetate (AA) in Men With Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-11-13

Completion:

2021-10-15

Conditions

• Prostatic Neoplasms

Interventions

• DRUG

No Results Yet

NCT04563494 | COMPLETED | PHASE4

126 participants

The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-10-23

Completion:

2023-05-24

Conditions

• Nausea and Vomiting, Postoperative

Interventions

• DRUG

Results Available

NCT04558866 | COMPLETED | PHASE2

51 participants

Extreme Bipolar Androgen Therapy With Darolutamide and Testosterone Cypionate in Patients With Metastatic Castration-Resistant Prostate Cancer (ExBAT Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-06-09

Completion:

2023-03-28

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04557059 | ACTIVE_NOT_RECRUITING | PHASE3

691 participants

A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-11-12

Completion:

2029-08-27

Conditions

• Prostatic Neoplasms

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04541030 | ACTIVE_NOT_RECRUITING

241 participants

Integrated Genomic Prostate Score With MRI Targeted Prostate Biopsies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2020-09-02

Completion:

2027-07-01

Conditions

• Prostate Cancer

No Results Yet

NCT04530565 | ACTIVE_NOT_RECRUITING | PHASE3

348 participants

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-01-25

Completion:

2028-07-01

Conditions

• B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT04504968 | COMPLETED | NA

713 participants

Effectiveness of a Multimodal Intervention on Function in Older Frail People With Diabetes in Latinamerican

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-02-14

Completion:

2024-04-30

Conditions

• Frailty Syndrome
• Frail Elderly Syndrome
• Diabetes Mellitus, Type 2

Interventions

• OTHER

No Results Yet

NCT04487080 | ACTIVE_NOT_RECRUITING | PHASE3

1074 participants

A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-09-30

Completion:

2023-08-11

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT04486378 | ACTIVE_NOT_RECRUITING | PHASE2

327 participants

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-03-08

Completion:

2026-11-30

Conditions

• Colorectal Cancer Stage II
• Colorectal Cancer Stage III

Interventions

• DRUG
• OTHER

No Results Yet

NCT04477486 | COMPLETED | PHASE2

13 participants

Study to Assess Effect of Oral Venetoclax Tablet in Combination With Oral Ibrutinib Capsule on Best Overall Response of Complete Response in Adult Japanese Participants With Relapsed/Refractory Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-09-23

Completion:

2022-02-09

Conditions

• Mantle Cell Lymphoma (MCL)

Interventions

• DRUG

Results Available

NCT04449874 | ACTIVE_NOT_RECRUITING | PHASE1

498 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-07-29

Completion:

2027-12-31

Conditions

• Non-Small Cell Lung Cancer
• Colorectal Cancer
• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04444921 | ACTIVE_NOT_RECRUITING | PHASE3

205 participants

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-11-17

Completion:

2027-03-31

Conditions

• Anal Basaloid Carcinoma
• Anal Canal Cloacogenic Carcinoma
• Metastatic Anal Squamous Cell Carcinoma
• Recurrent Anal Squamous Cell Carcinoma
• Stage III Anal Cancer AJCC v8
• Stage IV Anal Cancer AJCC v8
• Unresectable Anal Squamous Cell Carcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04431011 | COMPLETED

40 participants

Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-04-21

Completion:

2024-12-09

Conditions

• Normal Physiology

No Results Yet

NCT04427709 | TERMINATED | PHASE2

4 participants

Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-11-30

Completion:

2026-08-01

Conditions

• Chronic Pain
• Osteoarthritis, Knee

Interventions

• DRUG

No Results Yet

NCT04427293 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Preoperative Lenvatinib Plus Pembrolizumab in Early-Stage Triple-Negative Breast Cancer (TNBC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-07-09

Completion:

2027-07-31

Conditions

• Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04417660 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2020-12-26

Completion:

2026-12-31

Conditions

• Thymic Epithelial Tumor
• Recurrent Thymoma
• Thymic Cancer

Interventions

• DRUG

No Results Yet