Clinical Trials Updated in 2026

NCT04175600 | ACTIVE_NOT_RECRUITING | PHASE3

138 participants

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2020-01-16
Completion:: 2024-10-11

Conditions

Hypertension, Pulmonary

Interventions

DRUG

Results Available

NCT04170283 | ACTIVE_NOT_RECRUITING | PHASE3

955 participants

A Study to Evaluate Long-term Safety of Zanubrutinib Regimens in Participants With B-Cell Malignancies Who Participated in BeiGene Parent Studies of Zanubrutinib

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2020-01-16
Completion:: 2026-12-31

Conditions

B-cell Malignancies

Interventions

DRUG

No Results Yet

NCT04126161 | COMPLETED | NA

18 participants

HIP: Hip Imaging Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-11-01
Completion:: 2025-07-10

Conditions

Metabolic Profiling Muscle

Interventions

PROCEDURE
DEVICE

Results Available

NCT04108195 | ACTIVE_NOT_RECRUITING | PHASE1

290 participants

A Study of Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2020-02-21
Completion:: 2027-04-07

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT04090710 | COMPLETED | PHASE2

66 participants

SBRT With Combination Ipilimumab/Nivolumab for Metastatic Kidney Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2020-01-29
Completion:: 2026-04-23

Conditions

Metastatic Renal Cell Carcinoma

Interventions

DRUG
RADIATION

No Results Yet

NCT04065438 | RECRUITING | NA

35 participants

Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2020-01-01
Completion:: 2027-09-30

Conditions

Focal Segmental Glomerulosclerosis

Interventions

DEVICE

No Results Yet

NCT04039087 | COMPLETED | PHASE2/PHASE3

31 participants

Sildenafil Exercise: Role of PDE5 Inhibition

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-09-05
Completion:: 2024-06-30

Conditions

Cystic Fibrosis

Interventions

DRUG

Results Available

NCT04023552 | COMPLETED | PHASE3

8323 participants

Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-12-12
Completion:: 2026-07-16

Conditions

Cardiovascular Disease and Lipoprotein(a)

Interventions

DRUG

No Results Yet

NCT04014348 | RECRUITING

250 participants

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-10-20
Completion:: 2026-12-10

Conditions

Cardiovascular (CV) Risk

No Results Yet

NCT03964090 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-06-27
Completion:: 2027-07-01

Conditions

Central Nervous System Lymphoma
Secondary Central Nervous System Lymphoma

Interventions

DRUG

No Results Yet

NCT03963349 | ACTIVE_NOT_RECRUITING

150 participants

THERMOCOOL SMARTTOUCH®SF Catheters With Ablation Index Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-06-24
Completion:: 2026-12-31

Conditions

Paroxysmal Atrial Fibrillation

No Results Yet

NCT03937882 | COMPLETED | PHASE3

700 participants

Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-05-24
Completion:: 2020-11-08

Conditions

Dry Eye Syndromes
Dry Eye

Interventions

DRUG

Results Available

NCT03866382 | RECRUITING | PHASE2

314 participants

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-05-13
Completion:: 2027-02-28

Conditions

Bladder Adenocarcinoma
Bladder Clear Cell Adenocarcinoma
Bladder Mixed Adenocarcinoma
Bladder Neuroendocrine Carcinoma
Bladder Small Cell Neuroendocrine Carcinoma
Bladder Squamous Cell Carcinoma
Chromophobe Renal Cell Carcinoma
Collecting Duct Carcinoma
Invasive Bladder Giant Cell Urothelial Carcinoma
Invasive Bladder Lymphoepithelioma-Like Carcinoma
Invasive Bladder Nested Urothelial Carcinoma
Invasive Bladder Plasmacytoid Urothelial Carcinoma
Invasive Bladder Sarcomatoid Urothelial Carcinoma
Invasive Bladder Urothelial Carcinoma
Kidney Medullary Carcinoma
Large Cell Neuroendocrine Carcinoma
Malignant Testicular Leydig Cell Tumor
Malignant Testicular Sertoli Cell Tumor
Metastatic Bladder Carcinoma
Metastatic Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma
Metastatic Bladder Giant Cell Urothelial Carcinoma
Metastatic Bladder Large Cell Neuroendocrine Carcinoma
Metastatic Bladder Lipid-Rich Urothelial Carcinoma
Metastatic Bladder Micropapillary Urothelial Carcinoma
Metastatic Bladder Plasmacytoid Urothelial Carcinoma
Metastatic Bladder Sarcomatoid Urothelial Carcinoma
Metastatic Bladder Small Cell Neuroendocrine Carcinoma
Metastatic Bladder Squamous Cell Carcinoma
Metastatic Chromophobe Renal Cell Carcinoma
Metastatic Kidney Medullary Carcinoma
Metastatic Malignant Genitourinary System Neoplasm
Metastatic Papillary Renal Cell Carcinoma
Metastatic Penile Carcinoma
Metastatic Prostate Small Cell Neuroendocrine Carcinoma
Metastatic Sarcomatoid Renal Cell Carcinoma
Metastatic Urethral Carcinoma
Papillary Renal Cell Carcinoma
Sarcomatoid Renal Cell Carcinoma
Stage IV Bladder Cancer AJCC v8
Stage IV Penile Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8
Stage IV Urethral Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8
Urachal Adenocarcinoma
Urethral Clear Cell Adenocarcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT03854318 | RECRUITING

1000 participants

Longitudinal Studies of Patient With FPDMM

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-03-28
Completion:: 2028-12-31

Conditions

Inherited Hematological Diseases
Rare Diseases
FPDMM

No Results Yet

NCT03841617 | RECRUITING | PHASE2

30 participants

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-07-29
Completion:: 2035-11-01

Conditions

Thyroid Cancer

Interventions

DRUG
RADIATION
OTHER

No Results Yet

NCT03793179 | ACTIVE_NOT_RECRUITING | PHASE3

600 participants

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-04-05
Completion:: 2027-09-30

Conditions

Lung Non-Squamous Non-Small Cell Carcinoma
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT03783143 | COMPLETED

8524 participants

Prevalence and Incidence of Lassa Virus Infection in Southern Mali

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2020-12-04
Completion:: 2024-07-25

Conditions

Lassa Virus Infection

No Results Yet

NCT03775265 | ACTIVE_NOT_RECRUITING | PHASE3

475 participants

Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-06-03
Completion:: 2027-06-01

Conditions

Bladder Urothelial Carcinoma
Muscle Invasive Bladder Carcinoma
Stage II Bladder Cancer AJCC v8
Stage IIIA Bladder Cancer AJCC v8

Interventions

DRUG
PROCEDURE
OTHER
RADIATION

No Results Yet

NCT03767244 | ACTIVE_NOT_RECRUITING | PHASE3

2517 participants

A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-06-11
Completion:: 2026-12-01

Conditions

Prostatic Neoplasms

Interventions

DRUG

No Results Yet

NCT03737981 | ACTIVE_NOT_RECRUITING | PHASE3

465 participants

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-01-31
Completion:: 2025-01-17

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

DRUG
BIOLOGICAL
OTHER

Results Available

NCT03701282 | ACTIVE_NOT_RECRUITING | PHASE3

720 participants

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-02-12
Completion:: 2028-05-07

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT03660826 | ACTIVE_NOT_RECRUITING | PHASE2

288 participants

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-09-27
Completion:: 2024-12-06

Conditions

Endometrial Adenocarcinoma
Endometrial Mixed Cell Adenocarcinoma
Endometrial Serous Adenocarcinoma
Endometrial Undifferentiated Carcinoma
Endometrioid Adenocarcinoma
Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL

Results Available

NCT03651505 | ACTIVE_NOT_RECRUITING

782 participants

X-linked Hypophosphatemia Disease Monitoring Program

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-07-16
Completion:: 2032-12-31

Conditions

X-linked Hypophosphatemia
Hypophosphatemic Rickets

Interventions

OTHER

No Results Yet

NCT03619551 | ACTIVE_NOT_RECRUITING | PHASE2

56 participants

Conditioning SCID Infants Diagnosed Early

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-10-22
Completion:: 2027-12-01

Conditions

SCID

Interventions

DRUG
DEVICE

No Results Yet

NCT03595124 | ACTIVE_NOT_RECRUITING | PHASE2

15 participants

A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-01-08
Completion:: 2024-09-30

Conditions

Metastatic Renal Cell Carcinoma
Stage III Renal Cell Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8
TFE3-Rearranged Renal Cell Carcinoma
Unresectable Renal Cell Carcinoma

Interventions

DRUG
BIOLOGICAL

Results Available

NCT03523442 | ACTIVE_NOT_RECRUITING | PHASE1

19 participants

A Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Participants With Metastatic Castration-Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-08-31
Completion:: 2019-07-09

Conditions

Prostatic Neoplasms

Interventions

DRUG

No Results Yet

NCT03492177 | ACTIVE_NOT_RECRUITING | PHASE2

63 participants

A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-07-23
Completion:: 2022-03-28

Conditions

Pulmonary Arterial Hypertension

Interventions

DRUG

Results Available

NCT03473743 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

125 participants

A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-04-05
Completion:: 2022-09-30

Conditions

Urothelial Carcinoma

Interventions

DRUG

Results Available

NCT03457948 | COMPLETED | PHASE2

32 participants

Pembrolizumab With Liver-Directed or Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors and Liver Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-08-27
Completion:: 2025-07-31

Conditions

Metastatic Malignant Neoplasm in the Liver
Neuroendocrine Neoplasm

Interventions

PROCEDURE
BIOLOGICAL
DEVICE

Results Available

NCT03431350 | ACTIVE_NOT_RECRUITING | PHASE2

136 participants

A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-03-02
Completion:: 2021-08-31

Conditions

Prostatic Neoplasms, Castration-Resistant

Interventions

DRUG

Results Available

NCT03429036 | RECRUITING

1000 participants

Biospecimen Procurement for Head and Neck Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-05-23
Completion:: 2029-06-03

Conditions

Hearing Disorder
Oral Mucosal Disease
Pharyngeal Neoplasm
Head and Neck Neoplasms
Laryngeal Disease

No Results Yet

NCT03388619 | COMPLETED | PHASE1

30 participants

Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-01-17
Completion:: 2023-12-29

Conditions

Cancer Of Prostate
Prostate Neoplasms
Prostate Cancer
Neoplasms of Prostate
Prostatic Cancer

Interventions

RADIATION
DIAGNOSTIC_TEST
DRUG

Results Available

NCT03388606 | RECRUITING

4100 participants

Characterization and Treatment of Adolescent Depression

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-12-28
Completion:: 2027-07-01

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT03375242 | COMPLETED

97 participants

Safety and Efficacy of Xalkori ROS1

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-10-25
Completion:: 2026-08-10

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT03371719 | ACTIVE_NOT_RECRUITING | PHASE2

298 participants

Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-06-20
Completion:: 2025-03-10

Conditions

Recurrent Prostate Carcinoma
Stage III Prostate Adenocarcinoma AJCC v7
Stage IV Prostate Adenocarcinoma AJCC v7

Interventions

DRUG
RADIATION
OTHER

Results Available

NCT03366155 | COMPLETED | PHASE2

24 participants

Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-06-24
Completion:: 2025-11-13

Conditions

Colorectal Cancer
Liver Metastases
Colorectal Adenocarcinoma
Colorectal Cancer With Hepatic Metastases
Colorectal Carcinoma

Interventions

DEVICE
DRUG
PROCEDURE
DIAGNOSTIC_TEST

Results Available

NCT03337360 | COMPLETED | NA

1200 participants

The Impact of a Nutritional Supplement (Impryl®) on Male Fertility

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-04-23
Completion:: 2024-12-01

Conditions

Male Subfertility

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT03331250 | COMPLETED | PHASE2

13 participants

Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-01-18
Completion:: 2022-03-31

Conditions

Angiosarcoma
Epithelioid Hemangioendothelioma

Interventions

DRUG

Results Available

NCT03328325 | TERMINATED | PHASE4

152 participants

Age and Response to Flu Vaccines

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-12-14
Completion:: 2020-02-09

Conditions

Influenza
Influenza Immunisation

Interventions

BIOLOGICAL

Results Available

NCT03294460 | RECRUITING | PHASE1

128 participants

Nicotinic Receptor Genetic Variation and Alcohol Reward

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-06-10
Completion:: 2026-12-31

Conditions

Alcohol Drinking

Interventions

DRUG

No Results Yet