Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)
NCT03331250 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 13
Last updated 2025-12-23
Summary
This research study is studying a drug as a possible treatment for Angiosarcoma or Epithelioid hemangioendothelioma (EHE).
-The drug involved in this study is Eribulin
Conditions
- Angiosarcoma
- Epithelioid Hemangioendothelioma
Interventions
- DRUG
-
Eribulin
It may work by preventing the cancer cells from dividing and eventually cause the tumor cells to die
Sponsors & Collaborators
-
Eisai Inc.
collaborator INDUSTRY -
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Gregory Cote, MD, PhD · Massachusetts General Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-01-18
- Primary Completion
- 2023-07-21
- Completion
- 2026-02-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Local Therapies for Oligometastatic Non-Small Cell Lung Cancer Harboring Sensitizing EGFR Mutations
NCT02450591 ·Status: COMPLETED ·Phase: NA
-
An Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastatic Non Small Cell Lung Carcinoma
NCT00207116 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of Epitinib(HMPL-813) in Patients With Advanced Solid Tumors
NCT02590952 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma
NCT02491099 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors
NCT05983133 ·Status: TERMINATED ·Phase: PHASE1
-
Afatinib Plus Chemotherapy Against Esophageal or Lung Squamous Cell Carcinoma
NCT03486509 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of DBPR112 in Patients With Head and Neck Cancer and EGFR Mutated Lung Cancer
NCT03246854 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Assess the Efficacy of Erlotinib for Leptomeningeal Carcinomatosis in EGFR Mutation Positive Non-small Cell Lung Cancer
NCT00830245 ·Status: TERMINATED ·Phase: PHASE2
-
First-Line EGFR-1 Tyrosine Kinase Inhibition in Patients With NSCLC With Mutant EGFR Gene
NCT00339586 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase II Study of Sirolimus and Erlotinib in Recurrent/Refractory Germ Cell Tumors
NCT01962896 ·Status: TERMINATED ·Phase: PHASE2
-
Erlotinib as Neoadjuvant Treatment in Patients With Stage ⅢA N2 NSCLC With Activating EGFR Mutation.
NCT01217619 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Esophageal Cancer Or Cholangiocarcinoma
NCT02699606 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Tarceva (Erlotinib) in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Who Present EGFR Mutations
NCT01287754 ·Status: COMPLETED ·Phase: PHASE4
-
Phase II Study of Afatinib as Third- or Further-line Treatment for Patients With Stage IV Bronchial Adenocarcinoma, Harboring Wild-type EGFR, Expressing the Neurotensin - Neurotensin Receptor Complex
NCT02876081 ·Status: WITHDRAWN ·Phase: PHASE2
-
Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis
NCT04356118 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study of Erlotinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor Mutations
NCT01260181 ·Status: COMPLETED ·Phase: PHASE2
-
C11-Erlotinib PET/CT as a Tool for Identification and Characterization of Tumor With High Expression of Epidermal Growth Factor Receptor(EGFR).
NCT01717807 ·Status: UNKNOWN
-
Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction
NCT00030498 ·Status: COMPLETED ·Phase: PHASE1
-
Erlotinib as 1st Line Treatment in NSCLC Stage IIIB/IV
NCT00615758 ·Status: COMPLETED ·Phase: PHASE2
-
DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC
NCT06055153 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Study of EGFR-TKI to Asymptomatic Brain Metastases of NSCLC
NCT02250846 ·Status: UNKNOWN ·Phase: PHASE2
-
First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)
NCT05099172 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
NCT06521554 ·Status: RECRUITING ·Phase: PHASE1
-
Central Nervous System(CNS) Efficacy of Dacomitinib
NCT04675008 ·Status: UNKNOWN ·Phase: PHASE2
-
An Integrated Approach to Treating Recurrent Thoracic Carcinomas Resistant to Tyrosine Kinase Inhibitors
NCT02616211 ·Status: COMPLETED