Clinical Trials Updated in 2026

NCT03737981 | ACTIVE_NOT_RECRUITING | PHASE3

465 participants

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-01-31
Completion:: 2025-01-17

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

DRUG
BIOLOGICAL
OTHER

Results Available

NCT03701282 | ACTIVE_NOT_RECRUITING | PHASE3

720 participants

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-02-12
Completion:: 2028-05-07

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT03660826 | ACTIVE_NOT_RECRUITING | PHASE2

288 participants

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-09-27
Completion:: 2024-12-06

Conditions

Endometrial Adenocarcinoma
Endometrial Mixed Cell Adenocarcinoma
Endometrial Serous Adenocarcinoma
Endometrial Undifferentiated Carcinoma
Endometrioid Adenocarcinoma
Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL

Results Available

NCT03651505 | ACTIVE_NOT_RECRUITING

782 participants

X-linked Hypophosphatemia Disease Monitoring Program

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-07-16
Completion:: 2032-12-31

Conditions

X-linked Hypophosphatemia
Hypophosphatemic Rickets

Interventions

OTHER

No Results Yet

NCT03619551 | ACTIVE_NOT_RECRUITING | PHASE2

56 participants

Conditioning SCID Infants Diagnosed Early

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-10-22
Completion:: 2027-12-01

Conditions

SCID

Interventions

DRUG
DEVICE

No Results Yet

NCT03595124 | ACTIVE_NOT_RECRUITING | PHASE2

15 participants

A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-01-08
Completion:: 2024-09-30

Conditions

Metastatic Renal Cell Carcinoma
Stage III Renal Cell Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8
TFE3-Rearranged Renal Cell Carcinoma
Unresectable Renal Cell Carcinoma

Interventions

DRUG
BIOLOGICAL

Results Available

NCT03523442 | ACTIVE_NOT_RECRUITING | PHASE1

19 participants

A Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Participants With Metastatic Castration-Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-08-31
Completion:: 2019-07-09

Conditions

Prostatic Neoplasms

Interventions

DRUG

No Results Yet

NCT03492177 | ACTIVE_NOT_RECRUITING | PHASE2

63 participants

A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-07-23
Completion:: 2022-03-28

Conditions

Pulmonary Arterial Hypertension

Interventions

DRUG

Results Available

NCT03473743 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

125 participants

A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-04-05
Completion:: 2022-09-30

Conditions

Urothelial Carcinoma

Interventions

DRUG

Results Available

NCT03457948 | COMPLETED | PHASE2

32 participants

Pembrolizumab With Liver-Directed or Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors and Liver Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-08-27
Completion:: 2025-07-31

Conditions

Metastatic Malignant Neoplasm in the Liver
Neuroendocrine Neoplasm

Interventions

PROCEDURE
BIOLOGICAL
DEVICE

Results Available

NCT03431350 | ACTIVE_NOT_RECRUITING | PHASE2

136 participants

A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-03-02
Completion:: 2021-08-31

Conditions

Prostatic Neoplasms, Castration-Resistant

Interventions

DRUG

Results Available

NCT03429036 | RECRUITING

1000 participants

Biospecimen Procurement for Head and Neck Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-05-23
Completion:: 2029-06-03

Conditions

Hearing Disorder
Oral Mucosal Disease
Pharyngeal Neoplasm
Head and Neck Neoplasms
Laryngeal Disease

No Results Yet

NCT03388619 | COMPLETED | PHASE1

30 participants

Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-01-17
Completion:: 2023-12-29

Conditions

Cancer Of Prostate
Prostate Neoplasms
Prostate Cancer
Neoplasms of Prostate
Prostatic Cancer

Interventions

RADIATION
DIAGNOSTIC_TEST
DRUG

Results Available

NCT03388606 | RECRUITING

4100 participants

Characterization and Treatment of Adolescent Depression

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-12-28
Completion:: 2027-07-01

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT03375242 | COMPLETED

97 participants

Safety and Efficacy of Xalkori ROS1

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-10-25
Completion:: 2026-08-10

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT03371719 | ACTIVE_NOT_RECRUITING | PHASE2

298 participants

Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-06-20
Completion:: 2025-03-10

Conditions

Recurrent Prostate Carcinoma
Stage III Prostate Adenocarcinoma AJCC v7
Stage IV Prostate Adenocarcinoma AJCC v7

Interventions

DRUG
RADIATION
OTHER

Results Available

NCT03366155 | COMPLETED | PHASE2

24 participants

Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-06-24
Completion:: 2025-11-13

Conditions

Colorectal Cancer
Liver Metastases
Colorectal Adenocarcinoma
Colorectal Cancer With Hepatic Metastases
Colorectal Carcinoma

Interventions

DEVICE
DRUG
PROCEDURE
DIAGNOSTIC_TEST

Results Available

NCT03337360 | COMPLETED | NA

1200 participants

The Impact of a Nutritional Supplement (Impryl®) on Male Fertility

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-04-23
Completion:: 2024-12-01

Conditions

Male Subfertility

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT03331250 | COMPLETED | PHASE2

13 participants

Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-01-18
Completion:: 2022-03-31

Conditions

Angiosarcoma
Epithelioid Hemangioendothelioma

Interventions

DRUG

Results Available

NCT03328325 | TERMINATED | PHASE4

152 participants

Age and Response to Flu Vaccines

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-12-14
Completion:: 2020-02-09

Conditions

Influenza
Influenza Immunisation

Interventions

BIOLOGICAL

Results Available

NCT03294460 | RECRUITING | PHASE1

128 participants

Nicotinic Receptor Genetic Variation and Alcohol Reward

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2019-06-10
Completion:: 2026-12-31

Conditions

Alcohol Drinking

Interventions

DRUG

No Results Yet

NCT03244384 | ACTIVE_NOT_RECRUITING | PHASE3

739 participants

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-11-03
Completion:: 2026-10-31

Conditions

Localized Renal Pelvis and Ureter Urothelial Carcinoma
Locally Advanced Bladder Urothelial Carcinoma
Locally Advanced Renal Pelvis and Ureter Urothelial Carcinoma
Locally Advanced Ureter Urothelial Carcinoma
Locally Advanced Urothelial Carcinoma
Stage II Bladder Urothelial Carcinoma AJCC v6 and v7
Stage II Renal Pelvis and Ureter Cancer AJCC v7
Stage II Ureter Cancer AJCC v7
Stage III Bladder Urothelial Carcinoma AJCC v6 and v7
Stage III Renal Pelvis and Ureter Cancer AJCC v7
Stage III Ureter Cancer AJCC v7

Interventions

PROCEDURE
OTHER
BIOLOGICAL

No Results Yet

NCT03233711 | ACTIVE_NOT_RECRUITING | PHASE3

344 participants

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-07-05
Completion:: 2027-12-31

Conditions

Anal Basaloid Carcinoma
Anal Canal Cloacogenic Carcinoma
Anal Margin Squamous Cell Carcinoma
Stage IIB Anal Cancer AJCC v8
Stage III Anal Cancer AJCC v8

Interventions

PROCEDURE
BIOLOGICAL
OTHER

No Results Yet

NCT03218488 | ACTIVE_NOT_RECRUITING

135 participants

A Safety Study of Ustekinumab in the Treatment of Pediatric Participants Aged 6 Years and Older With Moderate to Severe Plaque Psoriasis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-10-25
Completion:: 2032-08-31

Conditions

Psoriasis

Interventions

DRUG

No Results Yet

NCT03162549 | ENROLLING_BY_INVITATION

2287 participants

CorEvitas Inflammatory Bowel Disease (IBD) Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-03-27
Completion:: 2100-12-31

Conditions

Inflammatory Bowel Diseases

No Results Yet

NCT03153475 | ACTIVE_NOT_RECRUITING | NA

400 participants

ATTUNE Revision System in the Revision Total Knee Arthroplasty Population

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-05-30
Completion:: 2029-03-31

Conditions

Revision Total Knee Arthroplasty

Interventions

DEVICE

No Results Yet

NCT03153449 | ACTIVE_NOT_RECRUITING | NA

400 participants

ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-09-19
Completion:: 2028-04-17

Conditions

Primary Knee Arthroplasty

Interventions

DEVICE

No Results Yet

NCT03145181 | ACTIVE_NOT_RECRUITING | PHASE1

302 participants

Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-05-16
Completion:: 2025-09-25

Conditions

Hematological Malignancies

Interventions

DRUG

No Results Yet

NCT03109197 | RECRUITING

1600 participants

Sudden Unexplained Death in Childhood (SUDC) Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2014-10-01
Completion:: 2028-11-30

Conditions

Sudden Unexplained Death Syndrome
Sudden Unexplained Death in Childhood

Interventions

OTHER

No Results Yet

NCT03076554 | ACTIVE_NOT_RECRUITING | PHASE2

56 participants

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-04-19
Completion:: 2027-03-30

Conditions

Thymoma
Thymic Carcinoma

Interventions

DRUG

No Results Yet

NCT03070587 | COMPLETED | NA

80 participants

A Pilot Study of Loving-Kindness Meditation for Social Anxiety Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-12-31
Completion:: 2020-06-30

Conditions

Social Anxiety Disorder
Compassion

Interventions

BEHAVIORAL

No Results Yet

NCT03063593 | ACTIVE_NOT_RECRUITING

500 participants

UK Infinity, Post-Market Clinical Follow-up Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-04-29
Completion:: 2029-12-31

Conditions

Arthritis, Rheumatoid
Post-traumatic Osteoarthritis
Degenerative Arthritis

No Results Yet

NCT03055013 | ACTIVE_NOT_RECRUITING | PHASE3

819 participants

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-04-28
Completion:: 2023-05-24

Conditions

Metastatic Renal Cell Carcinoma
Sarcomatoid Renal Cell Carcinoma
Stage II Renal Cell Cancer AJCC v7
Stage III Renal Cell Cancer AJCC v7
Unclassified Renal Cell Carcinoma

Interventions

PROCEDURE
BIOLOGICAL
OTHER

Results Available

NCT03053141 | RECRUITING

100 participants

RHythmia mAPping and Signal acquisitiOn for Data analYsis (RHAPSODY)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-05-31
Completion:: 2027-12-31

Conditions

Cardiac Arrythmias

Interventions

DEVICE

No Results Yet

NCT02997228 | ACTIVE_NOT_RECRUITING | PHASE3

120 participants

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-01-19
Completion:: 2027-06-01

Conditions

Metastatic Colorectal Adenocarcinoma
Stage IV Colorectal Cancer AJCC v7

Interventions

DRUG
BIOLOGICAL
PROCEDURE
OTHER

No Results Yet

NCT02941263 | COMPLETED

20 participants

Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-03-08
Completion:: 2024-05-22

Conditions

Age-Related Macular Degeneration

No Results Yet

NCT02919592 | ACTIVE_NOT_RECRUITING | NA

3603 participants

Memory Gel and Shape Combined Cohort

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-09-01
Completion:: 2031-09-16

Conditions

Primary Breast Augmentation
Primary Breast Reconstruction
Revision Breast Augmentation
Revision Breast Reconstruction

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT02911103 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

5 participants

Deep Brain Stimulation Surgery for Focal Hand Dystonia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-01-17
Completion:: 2029-02-02

Conditions

Dystonia
Focal Dystonia
Musician's Dystonia

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT02867592 | ACTIVE_NOT_RECRUITING | PHASE2

109 participants

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-05-18
Completion:: 2021-06-30

Conditions

Adrenal Cortical Carcinoma
Alveolar Soft Part Sarcoma
Central Nervous System Neoplasm
Childhood Clear Cell Sarcoma of Soft Tissue
Clear Cell Sarcoma of Soft Tissue
Ewing Sarcoma
Hepatoblastoma
Hepatocellular Carcinoma
Osteosarcoma
Recurrent Adrenal Cortical Carcinoma
Recurrent Alveolar Soft Part Sarcoma
Recurrent Clear Cell Sarcoma of Soft Tissue
Recurrent Ewing Sarcoma
Recurrent Hepatoblastoma
Recurrent Hepatocellular Carcinoma
Recurrent Kidney Wilms Tumor
Recurrent Malignant Solid Neoplasm
Recurrent Osteosarcoma
Recurrent Primary Malignant Central Nervous System Neoplasm
Recurrent Renal Cell Carcinoma
Recurrent Rhabdomyosarcoma
Recurrent Soft Tissue Sarcoma
Recurrent Thyroid Gland Medullary Carcinoma
Refractory Adrenal Cortical Carcinoma
Refractory Alveolar Soft Part Sarcoma
Refractory Clear Cell Sarcoma of Soft Tissue
Refractory Ewing Sarcoma
Refractory Hepatoblastoma
Refractory Hepatocellular Carcinoma
Refractory Malignant Solid Neoplasm
Refractory Osteosarcoma
Refractory Primary Central Nervous System Neoplasm
Refractory Primary Malignant Central Nervous System Neoplasm
Refractory Renal Cell Carcinoma
Refractory Rhabdomyosarcoma
Refractory Soft Tissue Sarcoma
Refractory Thyroid Gland Medullary Carcinoma
Refractory Wilms Tumor
Renal Cell Carcinoma
Rhabdomyosarcoma
Soft Tissue Sarcoma
Solid Neoplasm
Thyroid Gland Medullary Carcinoma
Wilms Tumor

Interventions

DRUG
OTHER

Results Available

NCT02858336 | COMPLETED | NA

38 participants

CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-01-12
Completion:: 2019-06-29

Conditions

Hormones

Interventions

BEHAVIORAL

No Results Yet