Clinical Trials

NCT03429036 | RECRUITING

1000 participants

Biospecimen Procurement for Head and Neck Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2018-05-23

Completion:

2029-06-03

Conditions

• Hearing Disorder
• Oral Mucosal Disease
• Pharyngeal Neoplasm
• Head and Neck Neoplasms
• Laryngeal Disease

No Results Yet

NCT03388619 | COMPLETED | PHASE1

30 participants

Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2018-01-17

Completion:

2023-12-29

Conditions

• Cancer Of Prostate
• Prostate Neoplasms
• Prostate Cancer
• Neoplasms of Prostate
• Prostatic Cancer

Interventions

• RADIATION
• DIAGNOSTIC_TEST
• DRUG

Results Available

NCT03388606 | RECRUITING

4100 participants

Characterization and Treatment of Adolescent Depression

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2017-12-28

Completion:

2027-07-01

Conditions

• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT03375242 | COMPLETED

97 participants

Safety and Efficacy of Xalkori ROS1

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2017-10-25

Completion:

2026-08-10

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT03371719 | ACTIVE_NOT_RECRUITING | PHASE2

298 participants

Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2018-06-20

Completion:

2025-03-10

Conditions

• Recurrent Prostate Carcinoma
• Stage III Prostate Adenocarcinoma AJCC v7
• Stage IV Prostate Adenocarcinoma AJCC v7

Interventions

• DRUG
• RADIATION
• OTHER

Results Available

NCT03366155 | COMPLETED | PHASE2

24 participants

Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2019-06-24

Completion:

2025-11-13

Conditions

• Colorectal Cancer
• Liver Metastases
• Colorectal Adenocarcinoma
• Colorectal Cancer With Hepatic Metastases
• Colorectal Carcinoma

Interventions

• DEVICE
• DRUG
• PROCEDURE
• DIAGNOSTIC_TEST

Results Available

NCT03337360 | COMPLETED | NA

1200 participants

The Impact of a Nutritional Supplement (Impryl®) on Male Fertility

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2018-04-23

Completion:

2024-12-01

Conditions

• Male Subfertility

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT03331250 | COMPLETED | PHASE2

13 participants

Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2018-01-18

Completion:

2022-03-31

Conditions

• Angiosarcoma
• Epithelioid Hemangioendothelioma

Interventions

• DRUG

Results Available

NCT03328325 | TERMINATED | PHASE4

152 participants

Age and Response to Flu Vaccines

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-12-14

Completion:

2020-02-09

Conditions

• Influenza
• Influenza Immunisation

Interventions

• BIOLOGICAL

Results Available

NCT03294460 | RECRUITING | PHASE1

128 participants

Nicotinic Receptor Genetic Variation and Alcohol Reward

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2019-06-10

Completion:

2026-12-31

Conditions

• Alcohol Drinking

Interventions

• DRUG

No Results Yet

NCT03244384 | ACTIVE_NOT_RECRUITING | PHASE3

739 participants

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-11-03

Completion:

2026-10-31

Conditions

• Localized Renal Pelvis and Ureter Urothelial Carcinoma
• Locally Advanced Bladder Urothelial Carcinoma
• Locally Advanced Renal Pelvis and Ureter Urothelial Carcinoma
• Locally Advanced Ureter Urothelial Carcinoma
• Locally Advanced Urothelial Carcinoma
• Stage II Bladder Urothelial Carcinoma AJCC v6 and v7
• Stage II Renal Pelvis and Ureter Cancer AJCC v7
• Stage II Ureter Cancer AJCC v7
• Stage III Bladder Urothelial Carcinoma AJCC v6 and v7
• Stage III Renal Pelvis and Ureter Cancer AJCC v7
• Stage III Ureter Cancer AJCC v7

Interventions

• PROCEDURE
• OTHER
• BIOLOGICAL

No Results Yet

NCT03233711 | ACTIVE_NOT_RECRUITING | PHASE3

344 participants

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2018-07-05

Completion:

2027-12-31

Conditions

• Anal Basaloid Carcinoma
• Anal Canal Cloacogenic Carcinoma
• Anal Margin Squamous Cell Carcinoma
• Stage IIB Anal Cancer AJCC v8
• Stage III Anal Cancer AJCC v8

Interventions

• PROCEDURE
• BIOLOGICAL
• OTHER

No Results Yet

NCT03218488 | ACTIVE_NOT_RECRUITING

135 participants

A Safety Study of Ustekinumab in the Treatment of Pediatric Participants Aged 6 Years and Older With Moderate to Severe Plaque Psoriasis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2017-10-25

Completion:

2032-08-31

Conditions

• Psoriasis

Interventions

• DRUG

No Results Yet

NCT03162549 | ENROLLING_BY_INVITATION

2287 participants

CorEvitas Inflammatory Bowel Disease (IBD) Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2017-03-27

Completion:

2100-12-31

Conditions

• Inflammatory Bowel Diseases

No Results Yet

NCT03153475 | ACTIVE_NOT_RECRUITING | NA

400 participants

ATTUNE Revision System in the Revision Total Knee Arthroplasty Population

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-05-30

Completion:

2029-03-31

Conditions

• Revision Total Knee Arthroplasty

Interventions

• DEVICE

No Results Yet

NCT03153449 | ACTIVE_NOT_RECRUITING | NA

400 participants

ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-09-19

Completion:

2028-04-17

Conditions

• Primary Knee Arthroplasty

Interventions

• DEVICE

No Results Yet

NCT03145181 | ACTIVE_NOT_RECRUITING | PHASE1

302 participants

Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-05-16

Completion:

2025-09-25

Conditions

• Hematological Malignancies

Interventions

• DRUG

No Results Yet

NCT03109197 | RECRUITING

1600 participants

Sudden Unexplained Death in Childhood (SUDC) Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2014-10-01

Completion:

2028-11-30

Conditions

• Sudden Unexplained Death Syndrome
• Sudden Unexplained Death in Childhood

Interventions

• OTHER

No Results Yet

NCT03076554 | ACTIVE_NOT_RECRUITING | PHASE2

56 participants

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-04-19

Completion:

2027-03-30

Conditions

• Thymoma
• Thymic Carcinoma

Interventions

• DRUG

No Results Yet

NCT03070587 | COMPLETED | NA

80 participants

A Pilot Study of Loving-Kindness Meditation for Social Anxiety Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2016-12-31

Completion:

2020-06-30

Conditions

• Social Anxiety Disorder
• Compassion

Interventions

• BEHAVIORAL

No Results Yet

NCT03063593 | ACTIVE_NOT_RECRUITING

500 participants

UK Infinity, Post-Market Clinical Follow-up Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2016-04-29

Completion:

2029-12-31

Conditions

• Arthritis, Rheumatoid
• Post-traumatic Osteoarthritis
• Degenerative Arthritis

No Results Yet

NCT03055013 | ACTIVE_NOT_RECRUITING | PHASE3

819 participants

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-04-28

Completion:

2023-05-24

Conditions

• Metastatic Renal Cell Carcinoma
• Sarcomatoid Renal Cell Carcinoma
• Stage II Renal Cell Cancer AJCC v7
• Stage III Renal Cell Cancer AJCC v7
• Unclassified Renal Cell Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• OTHER

Results Available

NCT03053141 | RECRUITING

100 participants

RHythmia mAPping and Signal acquisitiOn for Data analYsis (RHAPSODY)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2016-05-31

Completion:

2027-12-31

Conditions

• Cardiac Arrythmias

Interventions

• DEVICE

No Results Yet

NCT02997228 | ACTIVE_NOT_RECRUITING | PHASE3

120 participants

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2018-01-19

Completion:

2027-06-01

Conditions

• Metastatic Colorectal Adenocarcinoma
• Stage IV Colorectal Cancer AJCC v7

Interventions

• DRUG
• BIOLOGICAL
• PROCEDURE
• OTHER

No Results Yet

NCT02941263 | COMPLETED

20 participants

Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2017-03-08

Completion:

2024-05-22

Conditions

• Age-Related Macular Degeneration

No Results Yet

NCT02919592 | ACTIVE_NOT_RECRUITING | NA

3603 participants

Memory Gel and Shape Combined Cohort

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2016-09-01

Completion:

2031-09-16

Conditions

• Primary Breast Augmentation
• Primary Breast Reconstruction
• Revision Breast Augmentation
• Revision Breast Reconstruction

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT02911103 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

5 participants

Deep Brain Stimulation Surgery for Focal Hand Dystonia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2018-01-17

Completion:

2029-02-02

Conditions

• Dystonia
• Focal Dystonia
• Musician's Dystonia

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT02867592 | ACTIVE_NOT_RECRUITING | PHASE2

109 participants

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-05-18

Completion:

2021-06-30

Conditions

• Adrenal Cortical Carcinoma
• Alveolar Soft Part Sarcoma
• Central Nervous System Neoplasm
• Childhood Clear Cell Sarcoma of Soft Tissue
• Clear Cell Sarcoma of Soft Tissue
• Ewing Sarcoma
• Hepatoblastoma
• Hepatocellular Carcinoma
• Osteosarcoma
• Recurrent Adrenal Cortical Carcinoma
• Recurrent Alveolar Soft Part Sarcoma
• Recurrent Clear Cell Sarcoma of Soft Tissue
• Recurrent Ewing Sarcoma
• Recurrent Hepatoblastoma
• Recurrent Hepatocellular Carcinoma
• Recurrent Kidney Wilms Tumor
• Recurrent Malignant Solid Neoplasm
• Recurrent Osteosarcoma
• Recurrent Primary Malignant Central Nervous System Neoplasm
• Recurrent Renal Cell Carcinoma
• Recurrent Rhabdomyosarcoma
• Recurrent Soft Tissue Sarcoma
• Recurrent Thyroid Gland Medullary Carcinoma
• Refractory Adrenal Cortical Carcinoma
• Refractory Alveolar Soft Part Sarcoma
• Refractory Clear Cell Sarcoma of Soft Tissue
• Refractory Ewing Sarcoma
• Refractory Hepatoblastoma
• Refractory Hepatocellular Carcinoma
• Refractory Malignant Solid Neoplasm
• Refractory Osteosarcoma
• Refractory Primary Central Nervous System Neoplasm
• Refractory Primary Malignant Central Nervous System Neoplasm
• Refractory Renal Cell Carcinoma
• Refractory Rhabdomyosarcoma
• Refractory Soft Tissue Sarcoma
• Refractory Thyroid Gland Medullary Carcinoma
• Refractory Wilms Tumor
• Renal Cell Carcinoma
• Rhabdomyosarcoma
• Soft Tissue Sarcoma
• Solid Neoplasm
• Thyroid Gland Medullary Carcinoma
• Wilms Tumor

Interventions

• DRUG
• OTHER

Results Available

NCT02858336 | COMPLETED | NA

38 participants

CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-01-12

Completion:

2019-06-29

Conditions

• Hormones

Interventions

• BEHAVIORAL

No Results Yet

NCT02851706 | COMPLETED

1214 participants

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2016-09-01

Completion:

2025-05-29

Conditions

• Brain Cancer
• Brain Tumor
• Spine Cancer
• Spine Tumor
• Neoplasm

Interventions

• OTHER

No Results Yet

NCT02849496 | ACTIVE_NOT_RECRUITING | PHASE2

89 participants

Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-03-30

Completion:

2026-06-10

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Locally Advanced Unresectable Breast Carcinoma
• Metastatic Breast Carcinoma

Interventions

• DRUG
• PROCEDURE
• OTHER

No Results Yet

NCT02839850 | ACTIVE_NOT_RECRUITING | NA

540 participants

14022 ATTUNE Cementless RP Clinical Performance Evaluation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2016-09-01

Completion:

2027-09-01

Conditions

• Osteoarthritis

Interventions

• DEVICE

No Results Yet

NCT02839707 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

444 participants

Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2017-06-23

Completion:

2023-05-09

Conditions

• Fallopian Tube High Grade Serous Adenocarcinoma
• Ovarian High Grade Serous Adenocarcinoma
• Ovarian Seromucinous Carcinoma
• Primary Peritoneal High Grade Serous Adenocarcinoma
• Recurrent Fallopian Tube Carcinoma
• Recurrent Fallopian Tube Clear Cell Adenocarcinoma
• Recurrent Fallopian Tube Endometrioid Adenocarcinoma
• Recurrent Fallopian Tube Undifferentiated Carcinoma
• Recurrent Ovarian Carcinoma
• Recurrent Ovarian Clear Cell Adenocarcinoma
• Recurrent Ovarian Endometrioid Adenocarcinoma
• Recurrent Ovarian Undifferentiated Carcinoma
• Recurrent Platinum-Resistant Fallopian Tube Carcinoma
• Recurrent Platinum-Resistant Ovarian Carcinoma
• Recurrent Platinum-Resistant Primary Peritoneal Carcinoma
• Recurrent Primary Peritoneal Carcinoma
• Recurrent Primary Peritoneal Clear Cell Adenocarcinoma
• Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
• Recurrent Primary Peritoneal Undifferentiated Carcinoma

Interventions

• DRUG
• BIOLOGICAL
• PROCEDURE
• OTHER

Results Available

NCT02808780 | ACTIVE_NOT_RECRUITING

535 participants

An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2016-12-16

Completion:

2026-12-10

Conditions

• Ulcerative Colitis

No Results Yet

NCT02741440 | ACTIVE_NOT_RECRUITING

22 participants

Natural History of Spinocerebellar Ataxia Type 7 (SCA7)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2016-07-11

Completion:

2028-12-31

Conditions

• Spinocerebellar Ataxia

No Results Yet

NCT02724371 | ACTIVE_NOT_RECRUITING | NA

400 participants

A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2016-04-01

Completion:

2029-01-31

Conditions

• Breast Reconstruction
• Revision Breast Reconstruction

Interventions

• DEVICE

No Results Yet

NCT02706639 | COMPLETED

305 participants

Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2016-05-11

Completion:

2025-03-07

Conditions

• Williams Syndrome
• Supravalvular Aortic Stenosis
• Cardiovascular Disease

No Results Yet

NCT02659930 | ACTIVE_NOT_RECRUITING | PHASE1

62 participants

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2016-01-13

Completion:

2028-01-01

Conditions

• Kaposi Sarcoma

Interventions

• DRUG

No Results Yet

NCT02639325 | RECRUITING

100 participants

Tumor Related Epilepsy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2016-01-26

Completion:

2032-07-01

Conditions

• Epilepsy
• Cancer
• Brain Neoplasm

No Results Yet

NCT02639312 | RECRUITING

2400 participants

Natural History of Craniofacial Anomalies and Developmental Growth Variants

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2016-04-18

Completion:

2046-12-31

Conditions

• Prognathism
• Retrognathism
• Dentofacial Deformities

No Results Yet