Clinical Trials Updated in 2026

NCT01568658 | ACTIVE_NOT_RECRUITING

2323 participants

Genetic and Physical Study of Childhood Nerve and Muscle Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2012-03-20

Conditions

Muscular Dystrophies
Muscle Myopathies
Hereditary Spastic Paraplegias
Inherited Neuropathies
Inherited Neuromuscular Conditions

No Results Yet

NCT01511588 | COMPLETED

111 participants

Hormonal Regulation of Puberty and Fertility

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2012-04-25

Conditions

Endocrine Disease
Infertility
Hypogonadism
Amenorrhea
Adolescents

No Results Yet

NCT01503086 | COMPLETED | NA

45 participants

Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2014-07-30
Completion:: 2024-12-31

Conditions

Brain Neoplasm
Recurrent Brain Neoplasm

Interventions

PROCEDURE
OTHER

Results Available

NCT01496625 | RECRUITING

650 participants

National Eye Institute Biorepository for Retinal Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2012-06-18

Conditions

Age-Related Macular Degeneration
Diabetic Retinopathy
Von Hippel-Lindau Syndrome
Retinal Disease
Retinal Vein Occlusion

No Results Yet

NCT01425892 | RECRUITING

300 participants

The Pathogenesis and Natural History of Sjogren's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2012-01-18

Conditions

Sjogren's Syndrome
Salivary Gland
Pathogenesis

No Results Yet

NCT01324206 | RECRUITING

1000 participants

Development of 3T Magnetic Resonance Research Methods for NIA Studies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2008-11-03

Conditions

Normal Physiology

No Results Yet

NCT01272037 | ACTIVE_NOT_RECRUITING | PHASE3

5018 participants

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2011-02-28
Completion:: 2023-02-01

Conditions

Breast Ductal Carcinoma In Situ
Invasive Breast Carcinoma
Multicentric Breast Carcinoma
Multifocal Breast Carcinoma
Synchronous Bilateral Breast Carcinoma

Interventions

DRUG
OTHER

Results Available

NCT01239082 | ACTIVE_NOT_RECRUITING | NA

50126 participants

Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2012-04-30
Completion:: 2028-12-01

Conditions

Colorectal Cancer

Interventions

PROCEDURE

No Results Yet

NCT01224704 | COMPLETED | NA

75 participants

Water Deprivation Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2010-10-19
Completion:: 2018-09-09

Conditions

Obesity

Interventions

OTHER

No Results Yet

NCT01150708 | COMPLETED

180 participants

A Prospective Natural History Study of Patients With Syringomyelia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2010-08-03

Conditions

Syringomyelia
Arnold Chiari Deformity

No Results Yet

NCT01139476 | COMPLETED

1892 participants

Specimen Collection for Agricultural Health Study Cohort Pesticide Exposure Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2010-06-15

Conditions

Multiple Myeloma
Leukemia
MGUS
Monoclonal B-Cell Lymphocytosis

No Results Yet

NCT01117870 | COMPLETED | NA

31 participants

Assess the Effectiveness of Pulse RadioFrequency in Patients With Chronic Lumbar Radicular Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2010-07-31
Completion:: 2012-06-30

Conditions

Chronic Pain
Back Pain

Interventions

OTHER

Results Available

NCT01081262 | ACTIVE_NOT_RECRUITING | PHASE3

50 participants

Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2010-10-12
Completion:: 2015-02-25

Conditions

Borderline Ovarian Mucinous Tumor
Ovarian Mucinous Cystadenocarcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Ovarian Carcinoma
Stage IA Fallopian Tube Cancer AJCC v6 and v7
Stage IA Ovarian Cancer AJCC v6 and v7
Stage IB Fallopian Tube Cancer AJCC v6 and v7
Stage IB Ovarian Cancer AJCC v6 and v7
Stage IC Fallopian Tube Cancer AJCC v6 and v7
Stage IC Ovarian Cancer AJCC v6 and v7
Stage IIA Fallopian Tube Cancer AJCC v6 and v7
Stage IIA Ovarian Cancer AJCC V6 and v7
Stage IIB Fallopian Tube Cancer AJCC v6 and v7
Stage IIB Ovarian Cancer AJCC v6 and v7
Stage IIC Fallopian Tube Cancer AJCC v6 and v7
Stage IIC Ovarian Cancer AJCC v6 and v7
Stage IIIA Fallopian Tube Cancer AJCC v7
Stage IIIA Ovarian Cancer AJCC v6 and v7
Stage IIIB Fallopian Tube Cancer AJCC v7
Stage IIIB Ovarian Cancer AJCC v6 and v7
Stage IIIC Fallopian Tube Cancer AJCC v7
Stage IIIC Ovarian Cancer AJCC v6 and v7
Stage IV Fallopian Tube Cancer AJCC v6 and v7
Stage IV Ovarian Cancer AJCC v6 and v7

Interventions

BIOLOGICAL
DRUG
OTHER

Results Available

NCT00923026 | ENROLLING_BY_INVITATION

1150 participants

Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2009-06-15

Conditions

Melanoma
Adenocarcinoma
Carcinoma NOS
Neuroendocrine Tumors

No Results Yet

NCT00867464 | ACTIVE_NOT_RECRUITING

8670 participants

Extended Follow Up of Young Women in Costa Rica Who Received Vaccine for Human Papillomavirus Types 16 and 18 and Unvaccinated Controls

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2009-03-30
Completion:: 2026-12-23

Conditions

Anal Carcinoma
Cervical Carcinoma
Human Papillomavirus Infection
Human Papillomavirus-Related Cervical Carcinoma
Oral Cavity Carcinoma

Interventions

OTHER

No Results Yet

NCT00796887 | TERMINATED | PHASE2

27 participants

Randomized, Controlled Trial of Extended-Release Niacin (Niaspan®) to Augment Subacute Ischemic Stroke Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2009-04-30
Completion:: 2012-08-31

Conditions

Ischemic Stroke

Interventions

DRUG

Results Available

NCT00781612 | ACTIVE_NOT_RECRUITING | PHASE2

378 participants

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2008-10-16
Completion:: 2027-06-30

Conditions

Neoplasm Metastasis

Interventions

DRUG

No Results Yet

NCT00720161 | COMPLETED | NA

42 participants

Metformin in Children With Motor Deficit

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2006-11-30
Completion:: 2011-07-31

Conditions

Spina Bifida
Neuromuscular Diseases

Interventions

DRUG

No Results Yet

NCT00606346 | ACTIVE_NOT_RECRUITING

4970 participants

A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2007-05-31
Completion:: 2037-11-15

Conditions

Crohn's Disease
Ulcerative Colitis
Indeterminate Colitis
Inflammatory Bowel Diseases

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT00602641 | ACTIVE_NOT_RECRUITING | PHASE3

306 participants

Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2008-02-29
Completion:: 2014-01-18

Conditions

Multiple Myeloma

Interventions

OTHER
DRUG

Results Available

NCT00601900 | COMPLETED | PHASE3

394 participants

Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage IIIB or Stage IV Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2008-09-24
Completion:: 2014-06-30

Conditions

Invasive Breast Carcinoma
Recurrent Breast Carcinoma
Stage III Breast Cancer AJCC v6
Stage IV Breast Cancer AJCC v6 and v7

Interventions

BIOLOGICAL
OTHER
DRUG

Results Available

NCT00588770 | ACTIVE_NOT_RECRUITING | PHASE3

403 participants

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2008-08-08
Completion:: 2018-06-05

Conditions

Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Laryngeal Verrucous Carcinoma
Recurrent Lip and Oral Cavity Squamous Cell Carcinoma
Recurrent Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Oral Cavity Verrucous Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Recurrent Salivary Gland Carcinoma
Recurrent Sinonasal Squamous Cell Carcinoma
Salivary Gland Squamous Cell Carcinoma
Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7
Stage IV Major Salivary Gland Cancer AJCC v7
Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Laryngeal Verrucous Carcinoma AJCC v7
Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVA Major Salivary Gland Cancer AJCC v7
Stage IVA Oral Cavity Cancer AJCC v6 and v7
Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Laryngeal Verrucous Carcinoma AJCC v7
Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVB Major Salivary Gland Cancer AJCC v7
Stage IVB Oral Cavity Cancer AJCC v6 and v7
Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Sinonasal Squamous Cell Carcinoma AJCC v7
Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVC Laryngeal Verrucous Carcinoma AJCC v7
Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVC Major Salivary Gland Cancer AJCC v7
Stage IVC Oral Cavity Cancer AJCC v6 and v7
Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVC Sinonasal Squamous Cell Carcinoma AJCC v7
Tongue Carcinoma

Interventions

BIOLOGICAL
DRUG
OTHER

Results Available

NCT00569127 | ACTIVE_NOT_RECRUITING | PHASE3

427 participants

Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2007-12-01
Completion:: 2015-01-01

Conditions

Colorectal Neuroendocrine Tumor G1
Gastric Neuroendocrine Tumor G1
Neuroendocrine Neoplasm
Neuroendocrine Tumor
Neuroendocrine Tumor G2

Interventions

BIOLOGICAL
OTHER
DRUG

Results Available

NCT00508547 | ACTIVE_NOT_RECRUITING

20167 participants

Psoriasis Longitudinal Assessment and Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2007-06-21
Completion:: 2029-12-31

Conditions

Psoriasis

No Results Yet

NCT00433511 | ACTIVE_NOT_RECRUITING | PHASE3

4994 participants

Doxorubicin Hydrochloride, Cyclophosphamide, and Paclitaxel With or Without Bevacizumab in Treating Patients With Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2007-11-02
Completion:: 2014-01-07

Conditions

Breast Adenocarcinoma

Interventions

BIOLOGICAL
DRUG
OTHER

Results Available

NCT00340405 | COMPLETED

9759 participants

Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 1992-04-30
Completion:: 2025-11-25

Conditions

Lung Cancer

No Results Yet

NCT00340132 | COMPLETED

1759 participants

Cross-Sectional and Longitudinal Studies of "Pre-Diabetes" in the Pima Indians

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 1983-01-01

Conditions

Weight Gain
Overweight
Insulin Resistance
Obesity
Diabetes Mellitus, Type 2

No Results Yet

NCT00315380 | RECRUITING

700 participants

Longitudinal Study for Eosinophilic Granulomatosis With Polyangiitis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2006-04-30
Completion:: 2028-12-31

Conditions

Eosinophilic Granulomatosis With Polyangiitis
Churg-Strauss Syndrome

No Results Yet

NCT00310180 | ACTIVE_NOT_RECRUITING | PHASE3

10273 participants

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2006-04-07
Completion:: 2018-03-02

Conditions

Breast Adenocarcinoma
Hormone Receptor Positive
Stage IA Breast Cancer AJCC v7
Stage IB Breast Cancer AJCC v7
Stage IIA Breast Cancer AJCC v6 and v7
Stage IIB Breast Cancer AJCC v6 and v7
Stage IIIB Breast Cancer AJCC v7

Interventions

DRUG
OTHER
RADIATION

Results Available

NCT00109174 | RECRUITING | NA

200 participants

MRS Measurement of Glutamate and GABA Metabolism in Brain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2006-09-06
Completion:: 2030-01-11

Conditions

Normal Physiology

Interventions

DEVICE

No Results Yet

NCT00098475 | ACTIVE_NOT_RECRUITING | PHASE3

452 participants

Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2004-11-03
Completion:: 2008-11-30

Conditions

DS Stage I Multiple Myeloma
DS Stage II Multiple Myeloma
DS Stage III Multiple Myeloma

Interventions

DRUG
OTHER

Results Available

NCT00077909 | RECRUITING

750 participants

Study of Lung Proteins in Patients With Pneumonia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2004-02-20

Conditions

Pneumonia
Pulmonary Disease
Lung Disease

No Results Yet

NCT00076830 | COMPLETED

180 participants

Evaluation and Treatment of Patients With Connective Tissue Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2004-05-18

Conditions

Connective Tissue Disorders
Osteogenesis Imperfecta
Bone Diseases, Metabolic
Melorheostosis

No Results Yet

NCT00070564 | ACTIVE_NOT_RECRUITING | PHASE3

3294 participants

S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2003-11-30
Completion:: 2015-01-31

Conditions

Breast Cancer

Interventions

BIOLOGICAL
DRUG

Results Available

NCT00026884 | RECRUITING

5950 participants

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 1998-03-12

Conditions

Malignant Neoplasms
Hereditary Neoplastic Syndromes
Kidney Cancer
Renal Cancer
Bladder Cancer

No Results Yet

NCT00006421 | COMPLETED

200 participants

Breast Imaging Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-Up Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2000-10-25

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT00005917 | RECRUITING

60 participants

Study of Chediak-Higashi Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2002-09-10

Conditions

Chediak-Higashi Syndrome

No Results Yet

NCT00004571 | COMPLETED

3273 participants

Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2000-02-17

Conditions

Schizophrenia
Normal Physiology

No Results Yet

NCT00001853 | RECRUITING

2000 participants

Diabetes and Heart Disease Risk in Blacks

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 1998-10-21

Conditions

Cardiovascular Diseases
Diabetes
Obesity
Hypertension

No Results Yet

NCT00001727 | RECRUITING

500 participants

Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 1998-12-13

Conditions

McCune-Albright Syndrome

No Results Yet