Clinical Trials

NCT06979869 | RECRUITING

300 participants

Investigating Multigene Methylation Dynamics in Treatment Response Surveillance for Esophageal Carcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-27

Start Date:

2025-05-26

Completion:

2030-03-01

Conditions

• Esophageal Cancer

Interventions

• OTHER

No Results Yet

NCT06979336 | RECRUITING | PHASE2

224 participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-09-29

Completion:

2027-08-25

Conditions

• Ulcerative Colitis

Interventions

• DRUG

No Results Yet

NCT06978725 | RECRUITING | PHASE2/PHASE3

168 participants

A Study of Brepocitinib in Adults With Cutaneous Sarcoidosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-04-09

Completion:

2028-12-31

Conditions

• Cutaneous Sarcoidosis

Interventions

• DRUG

No Results Yet

NCT06961747 | RECRUITING | PHASE1

15 participants

A Study to Assess Zilucoplan Concentration in Breast Milk of Healthy Lactating Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-07-09

Completion:

2027-03-23

Conditions

• Healthy Participants

Interventions

• DRUG

No Results Yet

NCT06959524 | RECRUITING | NA

1616 participants

AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-08-21

Completion:

2028-03-31

Conditions

• Coronary Arterial Disease (CAD)
• de Novo Lesions in Native Coronary Arteries

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT06949410 | RECRUITING | PHASE1

36 participants

HER2 Vaccine for Locally Advanced Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2026-09-30

Completion:

2029-12-31

Conditions

• Breast Cancer
• HER2-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06934096 | RECRUITING | NA

39 participants

Ultrasound of the Spleen Utilizing Low-energy (Diagnostic Level) Insonification.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2026-01-08

Completion:

2027-01-07

Conditions

• Hemostasis
• Blood Biomarkers
• Ultrasound

Interventions

• DEVICE

No Results Yet

NCT06932003 | RECRUITING | PHASE1/PHASE2

12 participants

A Study to Explore the Safety, Tolerability, Efficacy, and Pharmacokinetics of LT-002-158 Tablets in Chinese Adult Patients With Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-07-08

Completion:

2028-10-30

Conditions

• Hidradenitis Suppurativa (HS)

Interventions

• DRUG

No Results Yet

NCT06931990 | RECRUITING | PHASE1/PHASE2

24 participants

A Study to Explore the Safety, Tolerability, Efficacy, and Pharmacokinetics of LT-002-158 Tablets in Chinese Adult Subjects With Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-06-04

Completion:

2028-02-17

Conditions

• Atopic Dermatitis (AD)

Interventions

• DRUG

No Results Yet

NCT06931041 | COMPLETED | PHASE3

25 participants

Comparing Efficacy of Autologous Serum Eye Drops With and Without Insulin in Autoimmune Dry Eye.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2024-02-01

Completion:

2025-06-01

Conditions

• Dry Eye
• Sjogren Syndrome

Interventions

• DRUG
• OTHER

No Results Yet

NCT06930352 | RECRUITING | PHASE2

70 participants

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2026-10-01

Completion:

2027-12-31

Conditions

• Acute Myeloid Leukemia

Interventions

• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT06916507 | RECRUITING

125 participants

Study to Assess Real Life Effectiveness of Foslevodopa/Foscarbidopa in Adult German Participants at Initial Stages of Advanced Parkinson's Disease (EARLY-FOS)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-27

Start Date:

2025-05-06

Completion:

2027-09-30

Conditions

• Parkinson's Disease

No Results Yet

NCT06900595 | RECRUITING | PHASE2

48 participants

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2026-02-22

Completion:

2029-06-02

Conditions

• Locally Advanced Adrenal Cortical Carcinoma
• Metastatic Adrenal Cortical Carcinoma
• Recurrent Adrenal Cortical Carcinoma
• Stage III Adrenal Cortical Carcinoma AJCC v8
• Stage IV Adrenal Cortical Carcinoma AJCC v8
• Unresectable Adrenal Cortical Carcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT06894758 | COMPLETED

196 participants

Development of a Rapid Diagnostic Test to Identify Crimean-Congo Hemorrhagic Fever - Research and Development Testing

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-27

Start Date:

2025-06-17

Completion:

2025-10-10

Conditions

• Infectious Diseases, Emerging

No Results Yet

NCT06887192 | RECRUITING | PHASE2

300 participants

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-08-15

Completion:

2027-12-31

Conditions

• Psychosis Associated With Alzheimer's Disease

Interventions

• DRUG

No Results Yet

NCT06884176 | WITHDRAWN | NA

0 participants

CVCs Versus Midline Catheters

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2026-06-30

Completion:

2027-06-30

Conditions

• Central Venous Catheter
• Midline Catheter
• Complication of Catheter

Interventions

• DEVICE

No Results Yet

NCT06882356 | RECRUITING | NA

2000 participants

The Glaucoma and Retinopathy Screening Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-07-16

Completion:

2030-09-30

Conditions

• Glaucoma

Interventions

• DEVICE

No Results Yet

NCT06881784 | RECRUITING | PHASE3

590 participants

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-05-06

Completion:

2027-12-01

Conditions

• NSCLC (Non-small Cell Lung Cancer)
• Non-Small Cell Lung Cancer
• NSCLC
• NSCLC (Non-small Cell Lung Carcinoma)
• NSCLC (Advanced Non-small Cell Lung Cancer)

Interventions

• DRUG

No Results Yet

NCT06881277 | RECRUITING | NA

200 participants

Effectiveness of a Smartphone App (PRIMI) to Promote Healthy Diet and Physical Activity After Pregnancy in Migrant Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-10-13

Completion:

2027-12-31

Conditions

• Postpartum

Interventions

• BEHAVIORAL

No Results Yet

NCT06867549 | RECRUITING | PHASE2

70 participants

Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage II

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-03-04

Completion:

2028-04-01

Conditions

• Depression

Interventions

• DRUG
• DIAGNOSTIC_TEST
• BEHAVIORAL

No Results Yet

NCT06855277 | RECRUITING | PHASE3

940 participants

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-07-01

Completion:

2028-09-29

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT06854016 | COMPLETED | NA

108 participants

Performance and Safety of LightForce® Therapy Lasers on Lateral Ankle Sprain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-04-11

Completion:

2025-11-17

Conditions

• Ankle Sprain 1St Degree
• Ankle Sprain 2Nd Degree
• Acute Pain

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06848075 | COMPLETED | PHASE2

431 participants

A Phase IIb, Randomized, Double-Blind, Placebo-Controlled Study of Elismetrep (K-304) in the Treatment of Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-03-11

Completion:

2025-08-04

Conditions

• Migraine

Interventions

• DRUG

Results Available

NCT06843356 | RECRUITING | NA

159 participants

Trial of Rescue Endovascular Treatment for Progressive Acute Mild Ischemic Stroke With Basilar Artery Occlusion With Extended Time Window

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-08-01

Completion:

2027-09-30

Conditions

• Acute Mild Ischemic Stroke
• Basilar Artery Occlusion
• Rescue Endovascular Treatment
• Extended Time Window

Interventions

• PROCEDURE

No Results Yet

NCT06827236 | RECRUITING | PHASE1/PHASE2

380 participants

A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-04-23

Completion:

2029-08-31

Conditions

• Locally Advanced Breast Cancer
• Unresectable Breast Carcinoma
• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06814795 | ACTIVE_NOT_RECRUITING | NA

32 participants

Medically Tailored Meals for Kids

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-11-25

Completion:

2026-10-21

Conditions

• Pediatric Cancer

Interventions

• OTHER

No Results Yet

NCT06809283 | COMPLETED

144 participants

Observational Prospective PMCF Study to Confirm Performance and Safety of Intelect® Devices in Real World

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-27

Start Date:

2025-03-10

Completion:

2026-02-26

Conditions

• Musculoskeletal Disorders
• Skeletal Disorder
• Muscle Disorder

No Results Yet

NCT06807190 | RECRUITING

630 participants

General Use-results Surveillance With Awiqli in Patients With Diabetes Mellitus

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-27

Start Date:

2025-04-15

Completion:

2027-07-31

Conditions

• Diabetes Mellitus, Type 1

Interventions

• DRUG

No Results Yet

NCT06793371 | RECRUITING | PHASE2

60 participants

AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-02-06

Completion:

2026-09-30

Conditions

• Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)

Interventions

• DRUG

No Results Yet

NCT06792942 | COMPLETED | NA

100 participants

Effect of a Nature-View Curtain on Pain, Anxiety, and Fear During Thyroid Biopsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-06-01

Completion:

2026-02-28

Conditions

• Thyroid Nodule (Diagnosis)

Interventions

• BEHAVIORAL

No Results Yet

NCT06790550 | COMPLETED | NA

60 participants

Effects of Self-Selected Music on Self-Injection Fear, Blood Glucose Testing Fear, and Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2024-03-31

Completion:

2025-04-30

Conditions

• Type 2 Diabetes Mellitus (T2DM)
• Pain
• Fear of Injections

Interventions

• BEHAVIORAL

No Results Yet

NCT06783647 | RECRUITING | PHASE2

250 participants

A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-06-11

Completion:

2026-12-24

Conditions

• Advanced Solid Tumour

Interventions

• DRUG

No Results Yet

NCT06782230 | RECRUITING

800 participants

ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-27

Start Date:

2024-08-31

Completion:

2027-03-01

Conditions

• Creation of an Italian Network of Biobanks of Rare Diseases

No Results Yet

NCT06770166 | COMPLETED | NA

120 participants

The Effect of Chamomile on Healing After Tooth Extraction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-01-01

Completion:

2025-12-30

Conditions

• Tooth Extraction Status Nos

Interventions

• OTHER

No Results Yet

NCT06762717 | RECRUITING

500 participants

FARAPULSE™ Pulsed Field Ablation System

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-27

Start Date:

2025-10-23

Completion:

2027-12-31

Conditions

• Paroxysmal AF

Interventions

• DEVICE

No Results Yet

NCT06759935 | COMPLETED | NA

104 participants

Performance and Safety of LightForce® Therapy Lasers on Shoulder Soft Tissue Inflammation Pain Reduction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-02-21

Completion:

2026-03-30

Conditions

• Shoulder Pain
• Shoulder Impingement Syndrome
• Rotator Cuff Tendinitis

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06758154 | RECRUITING | NA

92 participants

Efficacy and Olfactory Network of Electro-acupuncture for Subjective Cognitive Decline

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2024-12-28

Completion:

2027-12-31

Conditions

• Subjective Cognitive Decline (SCD)

Interventions

• DEVICE

No Results Yet

NCT06747936 | COMPLETED | PHASE3

129 participants

A Study to Evaluate the Efficacy and Safety of Co-administration of AD-2281 and AD-2282

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2025-02-03

Completion:

2025-05-30

Conditions

• Primary Hypercholesterolemia

Interventions

• DRUG

No Results Yet

NCT06744283 | RECRUITING

20 participants

Experience and Management of Cancer Screening-Related Anxiety in Fanconi Anemia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-27

Start Date:

2026-09-01

Completion:

2026-09-01

Conditions

• Fanconi Anemia

No Results Yet

NCT06739226 | NOT_YET_RECRUITING | PHASE1/PHASE2

30 participants

Combination Immunotherapy Targeting Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-27

Start Date:

2027-06-30

Completion:

2028-12-31

Conditions

• Melanoma

Interventions

• BIOLOGICAL

No Results Yet