A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)
NCT06978725 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2025-05-18
Summary
This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with cutaneous sarcoidosis.
Conditions
- Cutaneous Sarcoidosis
Interventions
- DRUG
-
Oral Brepocitinib
Drug: Oral Brepocitinib
- DRUG
-
Oral Placebo
Drug: Oral Placebo
Sponsors & Collaborators
-
Priovant Therapeutics, Inc.
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-04-09
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT03536884 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT03598790 ·Status: COMPLETED ·Phase: PHASE3
-
Bimekizumab in Plaque Psoriasis
NCT06336343 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Efficacy, Safety and Tolerability of CMK389 in Patients With Chronic Pulmonary Sarcoidosis
NCT04064242 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety and Tolerability, and the Efficacy of Si-544 in Adults With Psoriasis Vulgaris or Psoriatic Arthritis
NCT06191042 ·Status: COMPLETED ·Phase: PHASE1
-
Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
NCT04036435 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Efficacy Study of Humira in the Treatment of Cutaneous Sarcoidosis
NCT00731757 ·Status: WITHDRAWN ·Phase: PHASE2
-
A 24-week, Multicenter, proSpective stUdy to Evaluate the PASI 90 Clinical Response Rate and the Safety PRofile of sEcukinuMab 300 mg in Cw6-negativE and Cw6-positive Patients With Moderate to Severe Chronic Plaque-type Psoriasis (SUPREME)
NCT02394561 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Efficacy, Safety and Effect on Radiographic Progression of Brodalumab in Subjects With Psoriatic Arthritis
NCT02029495 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis
NCT04680975 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Adult Patients With Chronic Plaque Psoriasis
NCT03230292 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT03412747 ·Status: COMPLETED ·Phase: PHASE3
-
Secukinumab Study in PSOriasis Exploring pruRITUS Intensity and Lesional Biomarkers
NCT02362789 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Patients With Chronic Plaque Psoriasis
NCT03010527 ·Status: COMPLETED ·Phase: PHASE2
-
Effectiveness of Treatment With Tofacitinib in Patients With Psoriatic Arthritis in Routine Clinical Practice
NCT04517669 ·Status: COMPLETED
-
Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic Arthritis
NCT06176508 ·Status: RECRUITING ·Phase: PHASE2
-
Observational Study of Patients With Moderate to Severe Chronic Plaque Psoriasis
NCT03982394 ·Status: COMPLETED
-
Efficacy and Safety of 2 Secukinumab Regimens in 90kg or More Weight Group With Moderate/Severe Chronic Plaque Psoriasis
NCT03504852 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Chinese Adult Study Participants With Moderate to Severe Plaque Psoriasis
NCT06011733 ·Status: COMPLETED ·Phase: PHASE3
-
Cosentyx (Secukinumab) for the Treatment of Adult Onset Pityriasis Rubra Pilaris
NCT03342573 ·Status: COMPLETED ·Phase: PHASE1
-
Ixekizumab in Adult Patients With Lichen Planus and Lichen Planopilaris
NCT05030415 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Placebo and an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT03370133 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Efficacy and Safety of Brodalumab in Subjects With Psoriatic Arthritis
NCT02024646 ·Status: COMPLETED ·Phase: PHASE3
-
Acthar Gel in Participants With Pulmonary Sarcoidosis
NCT03320070 ·Status: COMPLETED ·Phase: PHASE4
-
POC Study to Evaluate BSI-045B in Moderate-to-severe Atopic Dermatitis
NCT05932654 ·Status: COMPLETED ·Phase: PHASE2