Clinical Trials

NCT05432882 | NOT_YET_RECRUITING | PHASE1/PHASE2

60 participants

CD19/22 Bi-specific CAR-T Cell Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2027-06-01

Completion:

2029-12-31

Conditions

• B Cell Malignancies

Interventions

• BIOLOGICAL

No Results Yet

NCT05394064 | TERMINATED | PHASE1/PHASE2

9 participants

A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-11-17

Completion:

2025-06-30

Conditions

• AMN
• AMN Gene Mutation
• X-ALD

Interventions

• GENETIC

Results Available

NCT05371964 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-05-04

Completion:

2027-02-28

Conditions

• Myelofibrosis

Interventions

• DRUG

No Results Yet

NCT05367440 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

174 participants

Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-06-02

Completion:

2031-04-11

Conditions

• Metastatic Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT05360719 | COMPLETED | NA

56 participants

Integrated Tele-exercise for Individuals With Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-04-30

Completion:

2026-01-31

Conditions

• Spinal Cord Injury

Interventions

• BEHAVIORAL

No Results Yet

NCT05350969 | COMPLETED | PHASE2

294 participants

Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial Infarction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-07-11

Completion:

2024-09-26

Conditions

• Myocardial Infarction, Acute
• Heart Failure, Left Sided

Interventions

• DRUG

Results Available

NCT05350774 | ENROLLING_BY_INVITATION | PHASE2

45 participants

Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2023-07-10

Completion:

2026-12-15

Conditions

• Systemic Inflammation
• Neuroinflammation
• Microvascular Thrombosis

Interventions

• DRUG

No Results Yet

NCT05350332 | RECRUITING | NA

151 participants

Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-06-30

Completion:

2027-06-30

Conditions

• Obstructive Sleep Apnea

Interventions

• DEVICE

No Results Yet

NCT05336435 | COMPLETED | NA

5175 participants

A Study of Population and Sex-specific Troponin Cutoffs for Ruling Out Acute Myocardial Infarction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-04-01

Completion:

2025-02-28

Conditions

• Coronary Syndrome, Acute
• Coronary Artery Disease
• Myocardial Infarction

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05334732 | ACTIVE_NOT_RECRUITING | NA

225 participants

Improving Communication and Adherence in Black Breast Cancer Survivors (Sisters Informing Sisters)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-03-01

Completion:

2027-02-28

Conditions

• Breast Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05328908 | TERMINATED | PHASE3

769 participants

A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-04-28

Completion:

2025-07-14

Conditions

• Colorectal Neoplasms

Interventions

• DRUG

Results Available

NCT05312879 | RECRUITING | PHASE2/PHASE3

466 participants

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-03-30

Completion:

2028-06-02

Conditions

• Proteinuric Kidney Disease

Interventions

• DRUG

No Results Yet

NCT05306600 | ACTIVE_NOT_RECRUITING

882 participants

Onco-Genomas Brasil: Mapping Breast and Prostate Cancer in the Brazilian Public Health System

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2022-11-09

Completion:

2026-12-31

Conditions

• Breast Cancer
• Prostate Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05303467 | RECRUITING | PHASE1

36 participants

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-07-30

Completion:

2026-10-31

Conditions

• Glioblastoma Multiforme
• Recurrent Glioblastoma

Interventions

• DEVICE

No Results Yet

NCT05281471 | RECRUITING | PHASE3

186 participants

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-08-31

Completion:

2026-12-31

Conditions

• Platinum-resistant Ovarian Cancer
• Platinum-refractory Ovarian Cancer
• Fallopian Tube Cancer
• Primary Peritoneal Cancer
• High-grade Serous Ovarian Cancer
• Endometrioid Ovarian Cancer
• Ovarian Clear Cell Carcinoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05276063 | COMPLETED | PHASE2/PHASE3

90 participants

A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-07-01

Completion:

2024-10-15

Conditions

• Thyroid Eye Disease
• Graves Orbitopathy
• Endocrine System Diseases
• Eye Diseases
• Thyroid Associated Ophthalmopathy
• Graves Ophthalmopathy
• Thyroid Diseases
• Orbital Diseases
• Proptosis
• IGF1R
• Exophthalmos
• Hashimoto

Interventions

• DRUG

Results Available

NCT05258825 | COMPLETED | PHASE4

37 participants

Preoperative Monoferric for Abdominal Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2023-04-18

Completion:

2025-06-09

Conditions

• Anemia
• Surgery

Interventions

• DRUG

No Results Yet

NCT05244486 | RECRUITING | NA

200 participants

Efficacy of RestoreX Penile Traction Therapy In Preserving Erectile Function Post-Prostatectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-03-12

Completion:

2028-09-14

Conditions

• Erectile Dysfunction Following Radical Prostatectomy

Interventions

• DEVICE

No Results Yet

NCT05238740 | RECRUITING | NA

168 participants

Comparison of Radiographic Fusion Rate and Clinical Outcome of ALIF and XLIF Performed With Either Recombinant Human Bone Morphogenetic Protein-2 or ViviGen®

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-10-27

Completion:

2032-12-31

Conditions

• Spondylosis
• Spondylolisthesis
• Degenerative Disc Disease

Interventions

• OTHER

No Results Yet

NCT05236036 | ACTIVE_NOT_RECRUITING | PHASE1

86 participants

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-08-08

Completion:

2029-01-03

Conditions

• Astrocytoma
• Glioblastoma
• Glioblastoma, IDH-Wildtype
• MGMT-Unmethylated Glioblastoma
• Recurrent Glioblastoma

Interventions

• DRUG
• OTHER
• RADIATION

No Results Yet

NCT05230459 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

9 participants

A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2023-05-15

Completion:

2028-12-31

Conditions

• Limb Girdle Muscular Dystrophy
• Limb-Girdle Muscular Dystrophy Type 2
• LGMD2I
• Muscular Dystrophy
• LGMD2
• LGMD
• FKRP
• FKRP Mutation
• Fukutin Related Protein

Interventions

• GENETIC
• DRUG

No Results Yet

NCT05219149 | COMPLETED

17 participants

CNS Qualitative Interview

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2022-01-03

Completion:

2024-06-30

Conditions

• Central Nervous System Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05218694 | COMPLETED | NA

122 participants

Coronary Computed Tomography Angiography For Optimized Invasive Coronary examInation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-05-01

Completion:

2025-02-28

Conditions

• Ischemic Heart Disease
• Coronary Artery Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05204147 | RECRUITING | PHASE1

20 participants

Actinium 225 Labeled Anti-CEA Antibody (Ac225-DOTA-M5A) for the Treatment of CEA Producing Advanced or Metastatic Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-06-02

Completion:

2027-09-10

Conditions

• Advanced Cancer
• Metastatic Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05176860 | COMPLETED | NA

31 participants

Evaluation of Novel Cone-Beam CT for Guidance and Adaptation of Precision Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-12-20

Completion:

2023-07-30

Conditions

• Lung Cancer
• Liver Cancer
• Breast Cancer
• Other Cancer

Interventions

• DEVICE

Results Available

NCT05170607 | ACTIVE_NOT_RECRUITING

120 participants

Investigation of Specific Biomarkers in Patients With Atrial Fibrillation Who Undergo Interventional Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2021-01-01

Completion:

2028-01-31

Conditions

• Atrial Fibrillation

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05144997 | ACTIVE_NOT_RECRUITING | PHASE4

76 participants

Lorlatinib Continuation Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-12-28

Completion:

2026-12-28

Conditions

• Non-Small-Cell Lung Cancer
• NSCLC

Interventions

• DRUG

No Results Yet

NCT05128175 | COMPLETED | PHASE1

15 participants

Comparative Bioavailability Study of Carbidopa/Levodopa Extended-Release Tablets Under Fasting and Fed Conditions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-10-29

Completion:

2021-12-09

Conditions

• Parkinson Disease

Interventions

• DRUG

No Results Yet

NCT05108558 | COMPLETED | PHASE4

40 participants

Efficacy of a Novel CCH Protocol for PD Among Prior Non-responders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-09-20

Completion:

2026-06-13

Conditions

• Peyronie's Disease

Interventions

• DRUG
• DEVICE

No Results Yet

NCT05102019 | RECRUITING | NA

380 participants

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-01-04

Completion:

2027-07-31

Conditions

• Refractory Angina

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05096273 | RECRUITING | NA

68 participants

Retraining and Control Therapy (ReACT): Sense of Control and Symptom Expectations as Targets of a Treatment for PNES

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-10-28

Completion:

2026-12-31

Conditions

• Convulsion, Non-Epileptic

Interventions

• BEHAVIORAL

No Results Yet

NCT05091580 | SUSPENDED | NA

500 participants

Effectiveness and Cost-Effectiveness of Depression Treatment for Individuals With TB in South Africa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2023-03-24

Completion:

2028-07-31

Conditions

• Depression
• Tuberculosis

Interventions

• BEHAVIORAL

No Results Yet

NCT05073185 | COMPLETED

209 participants

Resilience to the Effects of Advertising in Children

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-26

Start Date:

2022-05-01

Completion:

2026-07-30

Conditions

• Obesity, Childhood

No Results Yet

NCT05063565 | ACTIVE_NOT_RECRUITING | PHASE2

100 participants

TheraSphere With Durvalumab and Tremelimumab for HCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2023-11-03

Completion:

2027-06-30

Conditions

• Hepatocellular Carcinoma

Interventions

• DEVICE
• DRUG

No Results Yet

NCT05062954 | COMPLETED | NA

49 participants

Effects of a Polyphenol-rich Cranberry Extract on Cardiometabolic and Neurocognitive Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-10-21

Completion:

2025-01-09

Conditions

• Abdominal Obesity

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05053230 | ACTIVE_NOT_RECRUITING | NA

324 participants

A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-09-20

Completion:

2026-09-20

Conditions

• Head and Neck Cancer
• Head and Neck Tumor
• Thoracic Tumor
• Thoracic Cancer
• Gynecologic Cancer
• Gynecologic Tumor
• Melanoma
• Ovarian Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05044819 | ACTIVE_NOT_RECRUITING | PHASE4

154 participants

Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-07-07

Completion:

2027-08-01

Conditions

• Lennox Gastaut Syndrome
• Dravet Syndrome
• Tuberous Sclerosis Complex

Interventions

• DRUG

No Results Yet

NCT05018585 | TERMINATED | PHASE3

321 participants

A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2022-05-19

Completion:

2026-06-24

Conditions

• Type 1 Diabetes Mellitus

Interventions

• BIOLOGICAL
• DIETARY_SUPPLEMENT

No Results Yet

NCT05001737 | COMPLETED | PHASE3

33 participants

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2021-12-15

Completion:

2024-06-30

Conditions

• Macrophage Activation Syndrome
• Secondary Hemophagocytic Lymphohistiocytosis
• Still Disease
• Systemic Lupus Erythematosus
• SJIA
• AOSD
• MAS

Interventions

• DRUG

Results Available

NCT04963140 | TERMINATED | NA

39 participants

Self-Management Of Asthma By Forced Oscillation Technique

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-26

Start Date:

2020-11-16

Completion:

2024-04-24

Conditions

• Asthma

Interventions

• OTHER

No Results Yet