Clinical Trials

NCT07526116 | RECRUITING | PHASE1

88 participants

A First in Human Study to Assess Safety, Tolerability and Pharmacokinetics of a Single Dose of REGN22044 in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-06-05

Completion:

2027-02-08

Conditions

• Healthy Volunteer

Interventions

• DRUG

No Results Yet

NCT07524218 | RECRUITING | NA

50 participants

Effect of Meal Timing During Adjuvant Treatment for Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-08-12

Completion:

2029-08-31

Conditions

• Cancer

Interventions

• BEHAVIORAL
• OTHER
• PROCEDURE

No Results Yet

NCT07516483 | NOT_YET_RECRUITING | NA

40 participants

Thermal Preconditioning in Mastectomy Patients With Immediate Breast Reduction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-09-30

Completion:

2027-05-31

Conditions

• Breast Reconstruction After Mastectomy

Interventions

• OTHER

No Results Yet

NCT07508995 | NOT_YET_RECRUITING | PHASE2

40 participants

A Phase 2 Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With BCL-2 Inhibitor Sonrotoclax For Patients With Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-09-01

Completion:

2031-07-01

Conditions

• Chronic Lymphocytic Leukemia (CLL)

Interventions

• DRUG

No Results Yet

NCT07500545 | ACTIVE_NOT_RECRUITING | NA

580 participants

Community Health Adaptation & Resilience Mobilization (CHARM) HeatWise

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-03-29

Completion:

2028-06-02

Conditions

• Heat Illness

Interventions

• BEHAVIORAL

No Results Yet

NCT07496515 | NOT_YET_RECRUITING | PHASE2

168 participants

Omega-3 Supplementation vs Demodex vs Eyelid Cleanser for Pediatric Chalazia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-10-01

Completion:

2026-12-01

Conditions

• Pediatric Chalazia

Interventions

• DIETARY_SUPPLEMENT
• DEVICE
• DRUG

No Results Yet

NCT07492680 | RECRUITING | PHASE2

260 participants

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-07-27

Completion:

2028-08-15

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT07488923 | RECRUITING | PHASE1

110 participants

A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-06-23

Completion:

2028-03-31

Conditions

• Small Cell Lung Cancer (SCLC )
• Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)
• Gastroenteropancreatic NEC (GEP NEC)
• Neuroendocrine Prostate Cancer (NEPC)

Interventions

• BIOLOGICAL

No Results Yet

NCT07486869 | RECRUITING | PHASE2

5 participants

Emapalumab MDA5 Rapidly Progressive Interstitial Lung Disease (RP-ILD) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-07-23

Completion:

2027-07-31

Conditions

• Dermatomyositis
• Dermatomyositis Sine Myositis
• Dermatomyositis With Myopathy
• Dermatomyositis With Respiratory Involvement
• Dermatomyositis With Organ Involvement
• Interstitial Lung Disease
• Interstitial Lung Disease Due to Connective Tissue Disease (Disorder)

Interventions

• DRUG

No Results Yet

NCT07480252 | RECRUITING | NA

90 participants

Tecar Therapy in Patients With Lumbar Radiculopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-04-15

Completion:

2028-04-15

Conditions

• Lumbar Radiculopathy

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT07476222 | RECRUITING

600 participants

Anthropometric, Functional and Lifestyle Factors Associated With Testosterone Levels in Middle-Aged Men

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2026-06-01

Completion:

2027-12-31

Conditions

• Testosterone Deficiency
• Male Hypogonadism

Interventions

• OTHER

No Results Yet

NCT07466316 | RECRUITING | PHASE3

342 participants

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-07-14

Completion:

2031-03-31

Conditions

• Rhabdomyosarcoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION
• OTHER

No Results Yet

NCT07465289 | NOT_YET_RECRUITING | PHASE3

100 participants

A Study to Evaluate The Long-Term Safety And Efficacy of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-09-16

Completion:

2031-01-23

Conditions

• Ocular Myasthenia Gravis

Interventions

• DRUG

No Results Yet

NCT07458360 | RECRUITING | NA

80 participants

FRONT Block for Quality of Recovery After Total Hip Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-04-25

Completion:

2026-10-05

Conditions

• Osteoarthritis of the Hip
• Postoperative Pain
• Quality of Recovery

Interventions

• PROCEDURE

No Results Yet

NCT07454837 | RECRUITING | PHASE2/PHASE3

120 participants

Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-26

Completion:

2027-08-31

Conditions

• Chronic Hepatitis D

Interventions

• DRUG

No Results Yet

NCT07450495 | COMPLETED | NA

80 participants

Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-02-25

Completion:

2026-02-25

Conditions

• Chalazion

Interventions

• DRUG

No Results Yet

NCT07446712 | RECRUITING | NA

60 participants

Hyperbaric Oxygen Therapy in Complex Regional Pain Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-04-01

Completion:

2028-04-30

Conditions

• Chronic Pain
• Complex Regional Pain Syndrome

Interventions

• PROCEDURE

No Results Yet

NCT07444931 | RECRUITING

1500 participants

Validation of Sudden Cardiac Arrest Risk Factors in Patients With CAD

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2025-01-05

Completion:

2027-12-31

Conditions

• Coronary Arterial Disease (CAD)
• Sudden Cardiac Arrest
• Sudden Cardiac Death

No Results Yet

NCT07443085 | COMPLETED | PHASE2

75 participants

Effect of Dexmedetomidine Dosage on Postoperative Delirium in Geriatric Orthopedic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-26

Completion:

2026-07-01

Conditions

• Delirium - Postoperative

Interventions

• DRUG

No Results Yet

NCT07442929 | COMPLETED

2 participants

Crystallization of LA and Adjuvant Mixtures in Cerebrospinal Fluid

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2025-09-01

Completion:

2026-08-20

Conditions

• Hydrocephalus

No Results Yet

NCT07441616 | NOT_YET_RECRUITING | NA

10 participants

Partial Range Of Field IOLs in DMEK-Enabled Procedures

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-10-31

Completion:

2028-09-30

Conditions

• Cataract
• Fuchs Endothelial Corneal Dystrophy

Interventions

• DEVICE

No Results Yet

NCT07441603 | RECRUITING | NA

788 participants

Efficacy of the Proactive Automatized Lifestyle Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-06-25

Completion:

2029-06-30

Conditions

• Health Risk Behaviors
• Tobacco Smoking
• Alcohol Use
• Unhealthy Diet, Exercise, Smoking, and Alcohol Use
• Unhealthy Diet
• Insufficient Physical Activity
• Vegetable Intake

Interventions

• BEHAVIORAL

No Results Yet

NCT07440758 | COMPLETED | NA

80 participants

Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-03-20

Completion:

2026-07-01

Conditions

• Laparoscopic Cholecystectomy
• Postoperative Sore Throat

Interventions

• DRUG

No Results Yet

NCT07439224 | RECRUITING | NA

60 participants

Qigong and Multicomponent Exercise in Panic Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2024-12-01

Completion:

2028-01-30

Conditions

• Panic Disorder
• Panic Disorder (With or Without Agoraphobia)
• Panic Attacks and Disorders
• Qigong
• Exercise
• Anxiety Disorders

Interventions

• OTHER

No Results Yet

NCT07437820 | NOT_YET_RECRUITING | NA

68 participants

Study Comparing Neoadjuvant Versus Adjuvant Stereotactic Radiotherapy of Brain Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-09-30

Completion:

2030-06-30

Conditions

• Brain Metastases, Adult

Interventions

• RADIATION
• PROCEDURE

No Results Yet

NCT07433153 | RECRUITING | NA

36 participants

Comparison of Smartphone and Community-Based Delivery of the Otago Exercise Program for Fall Risk in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-16

Completion:

2026-12-01

Conditions

• Frail Elderly
• Fall

Interventions

• BEHAVIORAL

No Results Yet

NCT07431112 | RECRUITING | PHASE1

54 participants

A Study of AIR-001 in Adults With Alpha-1 Antitrypsin Deficiency (AATD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-03-17

Completion:

2028-11-30

Conditions

• Alpha 1 Antitrypsin Deficiency

Interventions

• DRUG

No Results Yet

NCT07430202 | NOT_YET_RECRUITING | PHASE1

27 participants

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-09-30

Completion:

2030-09-30

Conditions

• Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC))

Interventions

• DRUG

No Results Yet

NCT07428447 | RECRUITING

300 participants

Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-18

Completion:

2027-02-28

Conditions

• Essential Tremor, Movement Disorders
• Essential Tremor
• Essential Tremor-plus

No Results Yet

NCT07425574 | RECRUITING

90 participants

A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-20

Completion:

2028-07-31

Conditions

• Stargardt Disease
• Stargardt Macular Dystrophy
• Stargardt-like Macular Dystrophy

Interventions

• OTHER

No Results Yet

NCT07420751 | COMPLETED | NA

18 participants

Assessment of Patient Experience With Auto-Captioning Glasses in NF2-Related-Schwannomatosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-19

Completion:

2026-08-06

Conditions

• NF2-related Schwannomatosis

Interventions

• DEVICE

No Results Yet

NCT07419217 | COMPLETED

73 participants

Professional Impact of Osteoarticular Trauma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-18

Completion:

2026-02-20

Conditions

• Rehabilitation
• Return to Work
• Occupational Health/Medicine
• Work Capacity Evaluation
• Disabled Persons
• Vocational Rehabilitation

No Results Yet

NCT07415382 | COMPLETED

200 participants

Frailty, Dual-Task Performance, and Activities of Daily Living in Older Adults

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-07

Completion:

2026-08-24

Conditions

• Older Adults (60 - 85 Years Old)

Interventions

• OTHER

No Results Yet

NCT07412262 | RECRUITING | PHASE2

32 participants

A Study of Chidamide Combined With Ivonescimab in the Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) With Acquired Resistance to Immunotherapy and High Yes-associated Protein (YAP) Expression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-08-28

Completion:

2028-03-31

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT07407738 | RECRUITING | NA

120 participants

ShockFast Intravascular Lithotripsy Device for Treatment of Calcified Coronary Lesions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-02-16

Completion:

2026-11-01

Conditions

• Coronary Arterial Disease
• Calcified Coronary Artery Disease

Interventions

• DEVICE

No Results Yet

NCT07407387 | ACTIVE_NOT_RECRUITING | NA

219 participants

Ensuring Clinical Appropriateness and Safety of Pharmacological Therapies in Nursing Home Residents

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-05-01

Completion:

2026-11-30

Conditions

• Inappropriate Prescribing

Interventions

• PROCEDURE

No Results Yet

NCT07406685 | RECRUITING | PHASE4

52 participants

The Comparison of Ibandronate and Zoledronic Acid After Denosumab Discontinuation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-08-20

Completion:

2030-08-31

Conditions

• Postmenopausal Osteoporosis
• Postmenopausal Osteopenia
• Primary Osteoporosis
• Osteoporosis

Interventions

• DRUG

No Results Yet

NCT07396129 | NOT_YET_RECRUITING | PHASE1/PHASE2

30 participants

Assessing the Efficacy of a High-Dose Lidocaine-Tetracaine Cream for the Treatment of Peripheral Neuropathic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-09-20

Completion:

2026-12-01

Conditions

• Neuropathic Chronic Pain

Interventions

• DRUG

No Results Yet

NCT07392619 | NOT_YET_RECRUITING | NA

76 participants

The Effect of Acupressure on Symptoms in Elderly Adults With Painful Diabetic Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-12-30

Completion:

2027-09-05

Conditions

• Painful Diabetic Peripheral Neuropathy (PDPN)
• Acupressure

Interventions

• OTHER

No Results Yet

NCT07391670 | RECRUITING | PHASE1

40 participants

A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-03-31

Completion:

2027-08-30

Conditions

• Solid Tumours

Interventions

• DRUG

No Results Yet