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Clinical Trials

Showing trials with last updates posted in 2026.

NCT04870944 | SUSPENDED | PHASE1/PHASE2
63 participants

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2022-01-28
Completion:
2026-12-31
Conditions
  • Diffuse Midline Glioma, H3 K27-Altered
  • Metastatic Malignant Neoplasm in the Central Nervous System
  • Recurrent Diffuse Intrinsic Pontine Glioma
  • Recurrent Diffuse Midline Glioma, H3 K27-Altered
  • Recurrent Lymphoma
  • Recurrent Malignant Solid Neoplasm
  • Recurrent Primary Malignant Central Nervous System Neoplasm
  • Refractory Lymphoma
  • Refractory Malignant Solid Neoplasm
  • Refractory Primary Malignant Central Nervous System Neoplasm
Interventions
  • PROCEDURE
  • DRUG
No Results Yet
NCT04851119 | RECRUITING | PHASE1/PHASE2
147 participants

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2021-11-08
Completion:
2028-06-30
Conditions
  • Colorectal Carcinoma
  • Endometrial Carcinoma
  • Melanoma
  • Neuroblastoma
  • Ovarian Carcinoma
  • Pancreatic Ductal Adenocarcinoma
  • Recurrent Desmoid Fibromatosis
  • Recurrent Ewing Sarcoma
  • Recurrent Hepatoblastoma
  • Recurrent Hepatocellular Carcinoma
  • Recurrent Malignant Solid Neoplasm
  • Recurrent Non-Hodgkin Lymphoma
  • Recurrent Osteosarcoma
  • Refractory Desmoid Fibromatosis
  • Refractory Ewing Sarcoma
  • Refractory Hepatoblastoma
  • Refractory Hepatocellular Carcinoma
  • Refractory Malignant Solid Neoplasm
  • Refractory Non-Hodgkin Lymphoma
  • Refractory Osteosarcoma
  • Solid Pseudopapillary Neoplasm of the Pancreas
  • Wilms Tumor
Interventions
  • PROCEDURE
  • DRUG
No Results Yet
NCT04847063 | RECRUITING | PHASE1
60 participants

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2021-10-19
Completion:
2033-12-30
Conditions
  • Peritoneal Mesothelioma
  • Peritoneal Carcinomatosis
  • Ovarian Cancer
  • Gastrointestinal Cancer
  • Appendiceal Cancer
  • Atypical Mesothelial Proliferation
  • Colorectal Cancer
Interventions
  • DRUG
  • PROCEDURE
No Results Yet
NCT04726241 | RECRUITING | PHASE1/PHASE2
960 participants

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2022-04-18
Completion:
2030-12-31
Conditions
  • Acute Lymphoblastic Leukemia
  • Acute Myeloid Leukemia
  • Acute Myeloid Leukemia Post Cytotoxic Therapy
  • Juvenile Myelomonocytic Leukemia
  • Mixed Phenotype Acute Leukemia
  • Myelodysplastic Syndrome
  • Myelodysplastic Syndrome Post Cytotoxic Therapy
  • Myeloid Leukemia Associated With Down Syndrome
Interventions
  • PROCEDURE
No Results Yet
NCT04684368 | RECRUITING | PHASE2
160 participants

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2021-07-13
Completion:
2029-12-21
Conditions
  • Central Nervous System Nongerminomatous Germ Cell Tumor
  • Choriocarcinoma
  • Embryonal Carcinoma
  • Immature Teratoma
  • Malignant Teratoma
  • Mixed Germ Cell Tumor
  • Pineal Region Germ Cell Tumor
  • Pineal Region Immature Teratoma
  • Pineal Region Yolk Sac Tumor
  • Suprasellar Germ Cell Tumor
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
  • OTHER
  • RADIATION
No Results Yet
NCT04670445 | COMPLETED | NA
199 participants

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2021-01-23
Completion:
2023-03-23
Conditions
  • Stage IV Melanoma
  • Advanced Lung Cancer
  • Stage IV Non-Small Cell Lung Cancer
  • Unresectable Non-Small Cell Lung Carcinoma
  • Unresectable Stage III Non-Small Cell Lung Cancer
  • Small Cell Lung Cancer Extensive Stage
  • Stage IV Merkel Cell Carcinoma
  • Stage IV Cutaneous Squamous Cell Carcinoma
  • Stage IV Basal Cell Carcinoma
  • Stage IV Breast Cancer
  • Stage IV Colorectal Cancer
  • Stage IV Gastric Cancer
  • Stage IV Esophageal Cancer
  • Stage IV Hepatocellular Cancer
  • Stage IV Renal Cell Carcinoma
  • Stage IV Bladder Cancer
  • Stage IV Head and Neck Squamous Cell Carcinoma
  • Stage IV Cervical Cancer
  • Stage IV Endometrial Cancer
  • Stage IV Mesothelioma
  • Immunotherapy
  • Immune Checkpoint Inhibitors
Interventions
  • OTHER
No Results Yet
NCT04626245 | ACTIVE_NOT_RECRUITING | NA
150 participants

Mindfulness & Mechanisms Study

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2022-06-13
Completion:
2026-09-30
Conditions
  • Hypertension in Pregnancy
Interventions
  • BEHAVIORAL
No Results Yet
NCT04510740 | ACTIVE_NOT_RECRUITING
1000 participants

Liver Cancer Registry Platform

Study Type:
OBSERVATIONAL
Last Updated:
2026-08-25
Start Date:
2020-08-09
Completion:
2026-09-30
Conditions
  • Hepatocellular Carcinoma (HCC)
  • Cholangiocarcinoma
Interventions
  • OTHER
No Results Yet
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