Clinical Trials

NCT06906809 | COMPLETED | PHASE1

37 participants

Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-04-03

Completion:

2025-10-13

Conditions

• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT06898983 | RECRUITING | PHASE2

97 participants

Efficacy and Safety Study of Romiplostim N01 for Cancer Treatment-induced Thrombocytopenia (CTIT) in the Treatment of Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-07-14

Completion:

2027-01-31

Conditions

• Cancer Treatment-induced Thrombocytopenia (CTIT)

Interventions

• DRUG

No Results Yet

NCT06892925 | ACTIVE_NOT_RECRUITING | PHASE2

59 participants

QL1706 Combined With Lenvatinib and GEMOX as First - Line Treatment for Unresectable Biliary Tract Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-06-14

Completion:

2026-12-31

Conditions

• Biliary Tract Tumors

Interventions

• DRUG

No Results Yet

NCT06890598 | RECRUITING | PHASE3

700 participants

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-03-27

Completion:

2029-05-31

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT06875206 | NOT_YET_RECRUITING | NA

28 participants

Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-11-01

Completion:

2028-06-30

Conditions

• Stroke
• Visual Field Defect
• Visual Field Defect Following Cerebrovascular Accident
• Hemianopia
• Quadrantanopia
• Occipital Lobe Infarct
• Visual Fields Hemianopsia

Interventions

• DEVICE

No Results Yet

NCT06872125 | RECRUITING | PHASE3

170 participants

A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-06-04

Completion:

2027-03-31

Conditions

• Dravet Syndrome

Interventions

• DRUG
• OTHER

No Results Yet

NCT06848491 | RECRUITING | NA

240 participants

Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-10-27

Completion:

2028-04-30

Conditions

• Obesity
• Cancer
• Physical Activity
• Cancer Survivorship
• Diet

Interventions

• BEHAVIORAL

No Results Yet

NCT06847321 | RECRUITING | PHASE2

300 participants

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-02-17

Completion:

2029-01-31

Conditions

• Alzheimer Disease
• Alzheimer Disease Due to P. Gingivalis

Interventions

• DRUG

No Results Yet

NCT06846671 | RECRUITING | PHASE3

250 participants

A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-04-10

Completion:

2028-05-15

Conditions

• CLL
• Chronic Lymphocytic Leukemia

Interventions

• DRUG

No Results Yet

NCT06835751 | ACTIVE_NOT_RECRUITING | NA

200 participants

Optimizing HIV Pre-exposure Prophylaxis (PrEP) Among Women Who Use Drugs in Tanzania

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-07-25

Completion:

2026-09-30

Conditions

• HIV
• Mental Health
• Substance Use (Drugs, Alcohol)

Interventions

• BEHAVIORAL

No Results Yet

NCT06835530 | RECRUITING | PHASE2

47 participants

A Combination of Rituximab and CC-99282 as Front-line Therapy for Older Frail Patients With Diffuse Large B-cells Non-Hodgkin Lymphoma Evaluated With a Simplified Geriatric Assessment (sGA): a Phase II Study of the Fondazione Italiana Linfomi (FIL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-04-09

Completion:

2030-04-30

Conditions

• Diffuse Large B Cell Non-Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT06817408 | ACTIVE_NOT_RECRUITING

1000 participants

Dynamics of Organ Damage and Immune Exhaustion During Sepsis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2025-03-25

Completion:

2026-12-31

Conditions

• Sepsis

Interventions

• OTHER

No Results Yet

NCT06816251 | COMPLETED | PHASE2

84 participants

A Phase II Clinical Study of HRS-1893 in Non-obstructive Hypertrophic Cardiomyopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-02-25

Completion:

2025-11-18

Conditions

• Non-obstructive Hypertrophic Cardiomyopathy

Interventions

• DRUG

No Results Yet

NCT06803680 | RECRUITING | PHASE1

90 participants

A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-03-18

Completion:

2028-04-29

Conditions

• Advanced Solid Tumor
• Metastatic Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06802523 | SUSPENDED | PHASE1

53 participants

Testing the Combination of Targeted Radiotherapy With Anti-Cancer Drugs, Venetoclax and ASTX-727, to Improve Outcomes for Adults With Newly Diagnosed Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-11-18

Completion:

2028-12-31

Conditions

• Acute Myeloid Leukemia

Interventions

• RADIATION
• PROCEDURE
• DRUG

No Results Yet

NCT06770582 | RECRUITING | PHASE2

160 participants

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-06-03

Completion:

2032-02-01

Conditions

• Non-Muscle Invasive Bladder Urothelial Carcinoma
• Recurrent Non-Muscle Invasive Bladder Urothelial Carcinoma
• Stage I Bladder Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER
• RADIATION

No Results Yet

NCT06747468 | ACTIVE_NOT_RECRUITING | PHASE3

75 participants

Avexitide for Treatment of Post-Bariatric Hypoglycemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-04-29

Completion:

2026-07-08

Conditions

• Post Bariatric Hypoglycemia

Interventions

• DRUG
• OTHER

No Results Yet

NCT06720948 | ENROLLING_BY_INVITATION

50 participants

The ION Facet Screw System Ambispective Evaluation

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2025-01-01

Completion:

2026-12-31

Conditions

• Intra-facet ION 3D Facet Screw System

Interventions

• DEVICE

No Results Yet

NCT06711887 | RECRUITING | PHASE3

348 participants

Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-05-19

Completion:

2035-08-01

Conditions

• Lupus Nephritis

Interventions

• DRUG

No Results Yet

NCT06711146 | RECRUITING | EARLY_PHASE1

36 participants

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Moderate to Severe Active SLE Clinical Research

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-12-24

Completion:

2026-12-01

Conditions

• Systemic Lupus Erythematosus

Interventions

• DRUG

No Results Yet

NCT06697808 | RECRUITING

169 participants

Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-24

Completion:

2027-04-30

Conditions

• Traumatic Brain Injury

No Results Yet

NCT06680232 | RECRUITING | PHASE1

45 participants

Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-14

Completion:

2026-12-31

Conditions

• HEPATITIS B CHRONIC

Interventions

• BIOLOGICAL

No Results Yet

NCT06672939 | RECRUITING | PHASE3

150 participants

A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-18

Completion:

2027-12-31

Conditions

• Obesity
• Overweight

Interventions

• DRUG

No Results Yet

NCT06672549 | RECRUITING | PHASE3

125 participants

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-18

Completion:

2027-02-28

Conditions

• Obesity
• Overweight

Interventions

• DRUG

No Results Yet

NCT06668805 | RECRUITING | PHASE2

30 participants

A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-22

Completion:

2027-03-31

Conditions

• Noonan Syndrome

Interventions

• DRUG

No Results Yet

NCT06668363 | COMPLETED | NA

130 participants

Enhancing HIV Prevention and Reducing Alcohol Use Among People Receiving STI Care in Lilongwe, Malawi

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-12-12

Completion:

2026-05-26

Conditions

• Alcohol Consumption
• PrEP Uptake
• Recent Heavy Drinking
• HIV Prevention
• HIV Treatment

Interventions

• BEHAVIORAL

No Results Yet

NCT06665555 | COMPLETED | PHASE1

34 participants

Plasma and Intrapulmonary Pharmacokinetics of Ceftibuten and Ledaborbactam in Healthy Adults (18-55 Years)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-04

Completion:

2025-03-13

Conditions

• Pharmacokinetics
• Healthy Volunteers

Interventions

• DRUG

Results Available

NCT06664502 | COMPLETED | PHASE1/PHASE2

38 participants

A 2-part Study Consisting of a Multiple Ascending Dose Safety Study in Participants With Macular Edema Following Branch Retinal Vein Occlusion and a Dose-finding Safety and Preliminary Efficacy Study in Participants With Either Diabetic Macular Edema or Neovascular Age-related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-12

Completion:

2026-03-25

Conditions

• Diabetic Macular Edema (DME)
• Neovascular Age-related Macular Degeneration (NVAMD)
• BRVO - Branch Retinal Vein Occlusion

Interventions

• DRUG

No Results Yet

NCT06658574 | COMPLETED | PHASE2

65 participants

Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-13

Completion:

2026-05-02

Conditions

• Post Operative Analgesia
• Bariatric Surgery
• Bariatric Surgery (Gastric Bypass)
• Bariatric Surgery Patients
• Perioperative Analgesia

Interventions

• DRUG

Results Available

NCT06655025 | COMPLETED | NA

32 participants

The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-10-08

Completion:

2024-09-08

Conditions

• Cardiac Surgery
• Postoperative Cognitive Dysfunction
• Neurologic Manifestations

Interventions

• DRUG

No Results Yet

NCT06637020 | COMPLETED | PHASE1

80 participants

Phase Ib Clinical Study of HDM1005 Injection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-06-21

Completion:

2025-03-28

Conditions

• Overweight and Obesity

Interventions

• DRUG

No Results Yet

NCT06633978 | ACTIVE_NOT_RECRUITING | NA

90 participants

Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-09-10

Completion:

2026-08-31

Conditions

• MCI
• Aging

Interventions

• DEVICE

No Results Yet

NCT06633952 | ACTIVE_NOT_RECRUITING | NA

90 participants

Accelerating Cognitive Gains From Digital Inverventions With Noninvasive Brain Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-08-31

Completion:

2026-08-31

Conditions

• Aging
• MCI

Interventions

• DEVICE

No Results Yet

NCT06629779 | RECRUITING | PHASE3

900 participants

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-10-22

Completion:

2026-12-02

Conditions

• Metastatic Castration-Resistant Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT06627569 | NOT_YET_RECRUITING | NA

132 participants

Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-09-01

Completion:

2030-08-30

Conditions

• Overweight/Obesity
• Stress

Interventions

• BEHAVIORAL

No Results Yet

NCT06626334 | TERMINATED | NA

27 participants

Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-10-23

Completion:

2026-04-25

Conditions

• Rib Fractures
• Pain, Acute

Interventions

• DEVICE

No Results Yet

NCT06622174 | RECRUITING | PHASE1

32 participants

Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-08-20

Completion:

2028-07-31

Conditions

• Non Small Cell Lung Cancer
• Metastatic Lung Cancer

Interventions

• RADIATION

No Results Yet

NCT06621316 | COMPLETED | PHASE1/PHASE2

74 participants

A Study of Safety and Tolerability of Multiple Doses of HRS-7535 in Obese Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-10-30

Completion:

2025-07-14

Conditions

• Overweight or Obesity

Interventions

• DRUG

No Results Yet

NCT06620302 | SUSPENDED | PHASE1/PHASE2

81 participants

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-06-12

Completion:

2031-12-30

Conditions

• Childhood Fibrolamellar Carcinoma
• Recurrent Childhood Fibrolamellar Carcinoma
• Recurrent Childhood Malignant Solid Neoplasm
• Recurrent Fibrolamellar Carcinoma
• Recurrent Malignant Solid Neoplasm
• Refractory Childhood Fibrolamellar Carcinoma
• Refractory Childhood Malignant Solid Neoplasm
• Refractory Fibrolamellar Carcinoma
• Refractory Malignant Solid Neoplasm

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT06590857 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

16 participants

Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-07-19

Completion:

2028-10-31

Conditions

• Metastatic Breast Cancer
• HER2-negative Breast Cancer
• ER+ Breast Cancer
• Advanced Breast Cancer
• Metastatic Breast Cancer With Bone Involvement
• Bone Metastases in Subjects With Advanced Breast Cancer
• ER-Positive HER2-Negative Breast Cancer
• Estrogen Receptor-positive Breast Cancer
• Hormone-sensitive Metastatic Breast Cancer
• Hormone-Sensitive Breast Cancer

Interventions

• DRUG

No Results Yet