Clinical Trials

NCT05987956 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

600 participants

Pharmacogenomics IND SNP Clinical Trial - Alectinib and Single Nucleotide Polymorphisms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-03-18

Completion:

2026-11-18

Conditions

• ALK-Positive Non-Small Cell Lung Cancer (NSCLC)

Interventions

• DRUG

No Results Yet

NCT05987826 | RECRUITING | PHASE2

40 participants

Study of Furmonertinib as Neoadjuvant Therapy for Resectable Stage Ⅱ-ⅢB EGFR Sensitive Mutant NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-09-19

Completion:

2028-08-31

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05985785 | RECRUITING | NA

100 participants

Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-07-19

Completion:

2027-12-31

Conditions

• Osteoarthritis of the Knee

Interventions

• OTHER
• DRUG

No Results Yet

NCT05985772 | RECRUITING | NA

140 participants

Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-04-20

Completion:

2029-12-31

Conditions

• Meniscus Tear, Tibial

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT05979298 | COMPLETED | PHASE2

40 participants

Efficacy of Plasmid Elenagen in Combination With Gemcitabine in Patients With Platinum-resistant Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-11-15

Completion:

2023-12-30

Conditions

• Ovarian Cancer
• Platinum-resistant Ovarian Cancer

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT05976919 | COMPLETED

80 participants

Evaluating Treatable Traits Across the Spectrum of Chronic Obstructive Airways Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2023-10-01

Completion:

2026-07-31

Conditions

• Airway Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05969002 | COMPLETED

10 participants

Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2023-08-25

Completion:

2025-12-01

Conditions

• B Cell
• Acute Lymphoblastic Leukemia
• Relapsed/Refractory

No Results Yet

NCT05966415 | ACTIVE_NOT_RECRUITING | PHASE2

64 participants

Endocalyx for Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-04-21

Completion:

2026-09-01

Conditions

• Chronic Heart Failure

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT05961267 | COMPLETED

318 participants

Study of Gynecological Follow-up of Patients With Autoimmune Disease or Inflammatory Rheumatism

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2023-07-24

Completion:

2024-06-28

Conditions

• Arthritis, Rheumatoid
• Spondylitis, Ankylosing
• Lupus Erythematosus, Systemic
• Scleroderma, Systemic
• Sjogren's Syndrome
• Mixed Connective Tissue Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT05951179 | RECRUITING | PHASE2

131 participants

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-09-15

Completion:

2031-10-31

Conditions

• Non-muscle Invasive Bladder Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT05948566 | RECRUITING | PHASE2

300 participants

Strategy for Improving Stroke Treatment Response

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-03-18

Completion:

2027-07-31

Conditions

• Ischemic Stroke

Interventions

• BIOLOGICAL

No Results Yet

NCT05925803 | ACTIVE_NOT_RECRUITING | PHASE3

314 participants

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-11-08

Completion:

2027-01-06

Conditions

• Systemic Sclerosis
• Scleroderma

Interventions

• COMBINATION_PRODUCT
• DRUG

No Results Yet

NCT05917665 | COMPLETED

45 participants

Early Digital, Analyte and Neurologic Biomarkers of Acute and Chronic Brain Injury and Recovery in CQT Instructors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2025-08-01

Completion:

2026-02-27

Conditions

• Traumatic Brain Injury

No Results Yet

NCT05901285 | RECRUITING | PHASE1

48 participants

Phase 1 Study of Intratumoral Administration of VAX014 With Expansion in Combination With a Checkpoint Inhibitor in Subjects With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-11-02

Completion:

2027-08-31

Conditions

• Advanced Solid Tumor
• Advanced Solid Tumors Appropriate for Treatment With Either Nivolumab or Pembrolizumab

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT05899608 | RECRUITING | PHASE3

1600 participants

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-10-26

Completion:

2028-12-31

Conditions

• Non-Small Cell Lung Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT05898932 | RECRUITING

300 participants

Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2023-06-01

Completion:

2027-04-30

Conditions

• Benign Prostatic Hyperplasia

Interventions

• OTHER

No Results Yet

NCT05883436 | ACTIVE_NOT_RECRUITING | NA

71 participants

Investigation of DEXA-C Anterior Cervical Interbody System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-02-22

Completion:

2026-12-31

Conditions

• Degenerative Disc Disease

Interventions

• DEVICE

No Results Yet

NCT05873387 | RECRUITING

2420 participants

Development of an Algorithm to Detect Pulmonary Hypertension Using an Electronic Stethoscope

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2023-07-12

Completion:

2027-05-31

Conditions

• Pulmonary Hypertension

Interventions

• DEVICE

No Results Yet

NCT05871970 | RECRUITING | PHASE2

38 participants

Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-10-18

Completion:

2026-12-31

Conditions

• Lymphatic Malformation

Interventions

• BIOLOGICAL

No Results Yet

NCT05825950 | RECRUITING

600 participants

Artificial Intelligence Prediction Tool in Non-muscle Invasive Bladder Cancer (NMIBC)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2024-01-25

Completion:

2026-09-30

Conditions

• Non-muscle-invasive Bladder Cancer

No Results Yet

NCT05819528 | RECRUITING

43 participants

Primary Cardiac Lymphoma: Italian Multicenter Experience

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2024-10-02

Completion:

2026-10-31

Conditions

• Primary Cardiac Lymphoma

No Results Yet

NCT05811403 | COMPLETED | NA

64 participants

Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-07-01

Completion:

2025-06-30

Conditions

• Irreversible Pulpitis

Interventions

• OTHER

No Results Yet

NCT05804344 | COMPLETED | NA

113 participants

Establish the Role of Premotor and Motor Cortices in tDCS-facilitated Speech Motor Learning

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-10-25

Completion:

2026-03-01

Conditions

• Healthy

Interventions

• DEVICE

No Results Yet

NCT05780879 | TERMINATED | PHASE2

10 participants

A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-06-03

Completion:

2025-08-16

Conditions

• Secondary Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT05775159 | ACTIVE_NOT_RECRUITING | PHASE2

294 participants

Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-04-24

Completion:

2026-10-27

Conditions

• Hepatocellular Carcinoma
• Biliary Tract Cancer

Interventions

• DRUG

No Results Yet

NCT05765812 | RECRUITING | PHASE1/PHASE2

116 participants

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-05-15

Completion:

2028-09-30

Conditions

• Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
• Astrocytoma, Grade III

Interventions

• DRUG
• RADIATION

No Results Yet

NCT05738304 | RECRUITING | NA

250 participants

Ureteral Stenting After Retrograde Intrarenal Surgery for Renal Stones

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-01-12

Completion:

2026-11-01

Conditions

• Kidney Stone
• Retrograde Intrarenal Surgery
• Ureteral Stent

Interventions

• PROCEDURE

No Results Yet

NCT05737693 | ACTIVE_NOT_RECRUITING | PHASE2

350 participants

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-08-21

Completion:

2030-08-01

Conditions

• Posttraumatic Stress Disorder

Interventions

• DRUG

No Results Yet

NCT05725837 | COMPLETED | PHASE2

130 participants

Effects of Paroxetine on Cardiovascular Function in Septic Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-06-10

Completion:

2026-01-15

Conditions

• Septic Shock
• Sepsis

Interventions

• DRUG

No Results Yet

NCT05687136 | RECRUITING | PHASE1

66 participants

Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and Tuvusertib (M1774) for Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-06-07

Completion:

2027-08-31

Conditions

• Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm
• Unresectable Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05666778 | COMPLETED | PHASE2

408 participants

Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-02-13

Completion:

2026-07-31

Conditions

• Bacterial Vaginosis
• Vaginal Microbiome
• Chlamydia Trachomatis Infection
• Neisseria Gonorrheae Infection
• Trichomonas Vaginitis

Interventions

• DEVICE

No Results Yet

NCT05649982 | ACTIVE_NOT_RECRUITING | NA

300 participants

Optimization of Guidance in a Digital Tool for Problematic Alcohol Use

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-01-11

Completion:

2026-12-31

Conditions

• Drinking Excessive

Interventions

• BEHAVIORAL

No Results Yet

NCT05627700 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2026-08-24

No Results Yet

NCT05623020 | RECRUITING | PHASE3

1116 participants

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-11-10

Completion:

2030-10-18

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05609994 | RECRUITING | PHASE1

48 participants

ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-07-15

Completion:

2027-08-31

Conditions

• Low Grade Glioma of Brain

Interventions

• DRUG

No Results Yet

NCT05579639 | ACTIVE_NOT_RECRUITING | PHASE2

256 participants

Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-04-04

Completion:

2026-09-11

Conditions

• Allogeneic Stem Cell Transplantation

Interventions

• OTHER

No Results Yet

NCT05554380 | ACTIVE_NOT_RECRUITING | PHASE2

33 participants

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-09-22

Completion:

2027-02-01

Conditions

• Locally Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm
• Unresectable Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05548452 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

80 participants

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-11-21

Completion:

2027-05-31

Conditions

• Liver Disease; Alcohol-Related
• Cirrhosis
• Alcohol Use Disorder

Interventions

• DRUG

No Results Yet

NCT05546580 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-11-14

Completion:

2026-01-30

Conditions

• Acute Myeloid Leukemia, in Relapse
• Acute Myeloid Leukemia Refractory

Interventions

• DRUG

No Results Yet

NCT05530356 | COMPLETED

57 participants

Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2022-09-30

Completion:

2024-06-19

Conditions

• Type 2 Diabetes
• Diabetes Type 2
• Diabetic Nephropathies
• Nephropathy
• Obesity
• Adolescent Obesity
• Diabetic Kidney Disease

Interventions

• DRUG
• PROCEDURE
• RADIATION

Results Available