Clinical Trials

NCT05517811 | RECRUITING

200 participants

Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2022-06-26

Completion:

2028-05-31

Conditions

• Liver Cancer
• Esophageal Cancer
• Colorectal Cancer
• Lung Adenocarcinoma
• Control
• Pancreas Cancer
• Biliary Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05511909 | RECRUITING | PHASE2

100 participants

Evaluating Buspirone to Treat Opioid Withdrawal

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-12-15

Completion:

2027-01-31

Conditions

• Opioid Use Disorder
• Opioid Withdrawal
• Opioid Craving
• Anxiety

Interventions

• DRUG

No Results Yet

NCT05509777 | RECRUITING | PHASE3

90 participants

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-03-13

Completion:

2027-12-31

Conditions

• Crohn's Disease

Interventions

• DRUG

No Results Yet

NCT05501704 | RECRUITING | PHASE2

60 participants

ETHAN - ET for Male BC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-10-11

Completion:

2027-04-01

Conditions

• Male Breast Cancer
• Hormone Receptor-positive Breast Cancer
• Hormone Receptor Negative Breast Carcinoma

Interventions

• DRUG

No Results Yet

NCT05492006 | COMPLETED | NA

54 participants

Immune Response and Affective States of Elderly and 50+ Individuals After Intentional and Indirect Contact With Nature

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-06-20

Completion:

2023-11-30

Conditions

• Elderly

Interventions

• BEHAVIORAL

No Results Yet

NCT05476575 | COMPLETED | NA

37 participants

The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-10-28

Completion:

2022-07-07

Conditions

• Pain, Acute

Interventions

• OTHER

No Results Yet

NCT05464082 | RECRUITING | PHASE2

80 participants

Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of TNBC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-01-06

Completion:

2026-09-30

Conditions

• Breast Cancer Recurrent

Interventions

• OTHER

No Results Yet

NCT05463848 | ACTIVE_NOT_RECRUITING | PHASE2

52 participants

Surgical Pembro +/- Olaparib w TMZ for rGBM

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-10-21

Completion:

2026-05-19

Conditions

• Glioblastoma
• Recurrent Glioblastoma

Interventions

• DRUG

No Results Yet

NCT05450094 | ENROLLING_BY_INVITATION | NA

19106 participants

Reducing Unmet Mental Health Need of African-American Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-11-01

Completion:

2028-06-30

Conditions

• Mental Health

Interventions

• BEHAVIORAL

No Results Yet

NCT05444361 | ENROLLING_BY_INVITATION | NA

216 participants

Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-09-15

Completion:

2027-08-31

Conditions

• Mastectomy; Lymphedema

Interventions

• DEVICE

No Results Yet

NCT05437341 | TERMINATED | PHASE1/PHASE2

60 participants

PSMA/CD70 Bi-specific CAR-T Cell Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Cancer Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT05437328 | TERMINATED | PHASE1/PHASE2

60 participants

GD2/CD56 Bi-specific CAR-T Cell Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Malignant Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT05436509 | TERMINATED | PHASE1/PHASE2

60 participants

CD19/79b Bi-specific CAR-T Cell Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• B Cell Malignancies

Interventions

• BIOLOGICAL

No Results Yet

NCT05434637 | RECRUITING | NA

72 participants

Somatosensory Tinnitus RCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-11-01

Completion:

2027-06-30

Conditions

• Tinnitus

Interventions

• OTHER

No Results Yet

NCT05426525 | COMPLETED | PHASE4

60 participants

Use of Empagliflozin to Treat Prediabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-10-13

Completion:

2026-04-30

Conditions

• PreDiabetes
• Prediabetic State
• Overweight and Obesity

Interventions

• DRUG

No Results Yet

NCT05388370 | ACTIVE_NOT_RECRUITING

124 participants

PASS of Paediatric Patients Initiating Selumetinib

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2022-05-23

Completion:

2028-05-23

Conditions

• Neurofibromatosis Type 1

No Results Yet

NCT05370183 | COMPLETED | NA

14 participants

Tenotomy of Biceps' Long Head by Mini-optics in Consultation (Hyperambulatory): What Advantage Compared to the Operating Room?

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-11-29

Completion:

2025-05-05

Conditions

• Shoulder Pain
• Biceps Tendon Disorder

Interventions

• PROCEDURE

No Results Yet

NCT05361811 | RECRUITING | NA

70 participants

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-01-10

Completion:

2027-06-01

Conditions

• Neurofibromatosis 1
• Noonan Syndrome
• Legius Syndrome
• Cardiofaciocutaneous Syndrome
• Costello Syndrome

Interventions

• BEHAVIORAL

No Results Yet

NCT05342155 | ACTIVE_NOT_RECRUITING

602 participants

Patient- Generated Health Data to Predict Childhood Cancer Survivorship Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2023-03-20

Completion:

2028-06-30

Conditions

• Survivorship
• Childhood Cancer

No Results Yet

NCT05336344 | COMPLETED | NA

452 participants

Supporting Family Caregivers of Persons With Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-07-15

Completion:

2026-04-10

Conditions

• Caregiver Stress Syndrome
• Anxiety
• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT05317026 | RECRUITING | NA

50 participants

Increased Early Pain Relief by Adding Vertebroplasty to SBRT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-11-22

Completion:

2028-12-31

Conditions

• Spine Metastases
• Radiation Therapy
• Pain

Interventions

• PROCEDURE

No Results Yet

NCT05307744 | TERMINATED | NA

41 participants

Effects of Lactobacillus Plantarum PS128 in Children With ASD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-07-15

Completion:

2024-04-03

Conditions

• Autism Spectrum Disorder

Interventions

• DIETARY_SUPPLEMENT
• OTHER

Results Available

NCT05305118 | RECRUITING | NA

50 participants

TSCS for Acute SCI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-03-18

Completion:

2027-01-12

Conditions

• Acute Spinal Cord Injury
• Blood Pressure
• Hypotension

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT05281484 | AVAILABLE

Three Intermediate Expanded Access Protocols (EAP) CNMAu8.EAP01, CNMAu8.EAP02, and CNMAu8.EAP06 for ALS

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-24

Conditions

• Amyotrophic Lateral Sclerosis

Interventions

• DRUG

No Results Yet

NCT05277753 | TERMINATED | PHASE1

10 participants

NGS-MRD Assessment of Combination Immunotherapies Targeting T-ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• T-Cell Acute Lymphoblastic Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT05262673 | TERMINATED | PHASE1

10 participants

NGS-MRD Assessment of Combination Immunotherapies Targeting B-ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• B-Cell Acute Lymphoblastic Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT05253131 | RECRUITING | PHASE2

41 participants

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-08-04

Completion:

2031-11-15

Conditions

• MPNST
• NF1
• Sarcoma

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT05249959 | ACTIVE_NOT_RECRUITING | PHASE2

49 participants

Consolidation With Loncastuximab Tesirine After a Short Course of Immunochemotherapy in BTKi-treated (or Intolerant) Relapsed/Refractory Mantle Cell Lymphoma Patients.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-03-21

Completion:

2027-03-31

Conditions

• Relapsed Mantle Cell Lymphoma
• Refractory Mantle Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT05183035 | RECRUITING | PHASE3

130 participants

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-10-01

Completion:

2027-02-28

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT05157672 | COMPLETED | EARLY_PHASE1

16 participants

Evaluating the Pharmacokinetics and Drug Interaction Potential of the Botanical Dietary Supplement Cinnamon

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-12-14

Completion:

2023-08-31

Conditions

• Interaction Drug Food

Interventions

• DIETARY_SUPPLEMENT
• DRUG

No Results Yet

NCT05156398 | RECRUITING | PHASE3

640 participants

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-02-28

Completion:

2031-11-29

Conditions

• Migraine

Interventions

• DRUG

No Results Yet

NCT05127837 | COMPLETED | NA

601 participants

CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-06-28

Completion:

2024-12-09

Conditions

• Psychosis
• Schizophrenia
• Schizo Affective Disorder
• Bipolar Disorder
• Depressive Disorder

Interventions

• BEHAVIORAL

Results Available

NCT05104866 | ACTIVE_NOT_RECRUITING | PHASE3

732 participants

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-10-18

Completion:

2024-07-24

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT05096481 | RECRUITING | PHASE2

120 participants

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-07-18

Completion:

2028-06-15

Conditions

• High Grade Glioma
• Diffuse Intrinsic Pontine Glioma
• Recurrent Medulloblastoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05091905 | COMPLETED | PHASE4

60 participants

Patient-Titrated Automated Intermittent Boluses of Local Anesthetic vs. a Continuous Infusion Via a Perineural Catheter for Postoperative Analgesia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-03-22

Completion:

2026-03-18

Conditions

• Pain, Acute Postoperative
• Trauma Injury

Interventions

• DRUG

No Results Yet

NCT05074264 | ACTIVE_NOT_RECRUITING | NA

1586 participants

Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-11-30

Completion:

2026-03-31

Conditions

• AIDS-Related Anal Carcinoma
• AIDS-Related Cervical Carcinoma
• High Grade Anal Intraepithelial Neoplasia
• High Grade Cervical Intraepithelial Neoplasia
• HIV Infection

Interventions

• PROCEDURE

No Results Yet

NCT05048368 | NOT_YET_RECRUITING | PHASE1

32 participants

Pharmacokinetics Study of Larotinib in Subjects With Impaired Hepatic Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-10-30

Completion:

2026-12-30

Conditions

• Esophageal Cancer
• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05035836 | RECRUITING | PHASE2

20 participants

A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-11-16

Completion:

2028-12-29

Conditions

• Breast Cancer
• HER2-positive

Interventions

• DRUG

No Results Yet

NCT05034536 | ACTIVE_NOT_RECRUITING | PHASE2

36 participants

PD-1 Antibody Therapy + Infliximab for Metastatic Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-02-07

Completion:

2027-06-30

Conditions

• Metastatic Melanoma

Interventions

• DRUG

No Results Yet

NCT05021029 | ENROLLING_BY_INVITATION

1000 participants

UC Davis Cohort of Pre-Malignant and Malignant Gastro-Intestinal DisEases Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2021-07-13

Completion:

2030-10-31

Conditions

• Intestinal Metaplasia
• Chronic Gastritis
• Atrophic Gastritis
• Autoimmune Gastritis
• Intestinal Dysplasia
• Gastric Polyps

No Results Yet