Clinical Trials

NCT05249959 | ACTIVE_NOT_RECRUITING | PHASE2

49 participants

Consolidation With Loncastuximab Tesirine After a Short Course of Immunochemotherapy in BTKi-treated (or Intolerant) Relapsed/Refractory Mantle Cell Lymphoma Patients.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-03-21

Completion:

2027-03-31

Conditions

• Relapsed Mantle Cell Lymphoma
• Refractory Mantle Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT05183035 | RECRUITING | PHASE3

130 participants

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-10-01

Completion:

2027-02-28

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT05157672 | COMPLETED | EARLY_PHASE1

16 participants

Evaluating the Pharmacokinetics and Drug Interaction Potential of the Botanical Dietary Supplement Cinnamon

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-12-14

Completion:

2023-08-31

Conditions

• Interaction Drug Food

Interventions

• DIETARY_SUPPLEMENT
• DRUG

No Results Yet

NCT05156398 | RECRUITING | PHASE3

640 participants

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-02-28

Completion:

2031-11-29

Conditions

• Migraine

Interventions

• DRUG

No Results Yet

NCT05127837 | COMPLETED | NA

601 participants

CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-06-28

Completion:

2024-12-09

Conditions

• Psychosis
• Schizophrenia
• Schizo Affective Disorder
• Bipolar Disorder
• Depressive Disorder

Interventions

• BEHAVIORAL

Results Available

NCT05104866 | ACTIVE_NOT_RECRUITING | PHASE3

732 participants

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-10-18

Completion:

2024-07-24

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT05096481 | RECRUITING | PHASE2

120 participants

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-07-18

Completion:

2028-06-15

Conditions

• High Grade Glioma
• Diffuse Intrinsic Pontine Glioma
• Recurrent Medulloblastoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05091905 | COMPLETED | PHASE4

60 participants

Patient-Titrated Automated Intermittent Boluses of Local Anesthetic vs. a Continuous Infusion Via a Perineural Catheter for Postoperative Analgesia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-03-22

Completion:

2026-03-18

Conditions

• Pain, Acute Postoperative
• Trauma Injury

Interventions

• DRUG

No Results Yet

NCT05074264 | ACTIVE_NOT_RECRUITING | NA

1586 participants

Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-11-30

Completion:

2026-03-31

Conditions

• AIDS-Related Anal Carcinoma
• AIDS-Related Cervical Carcinoma
• High Grade Anal Intraepithelial Neoplasia
• High Grade Cervical Intraepithelial Neoplasia
• HIV Infection

Interventions

• PROCEDURE

No Results Yet

NCT05048368 | NOT_YET_RECRUITING | PHASE1

32 participants

Pharmacokinetics Study of Larotinib in Subjects With Impaired Hepatic Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-10-30

Completion:

2026-12-30

Conditions

• Esophageal Cancer
• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05035836 | RECRUITING | PHASE2

20 participants

A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-11-16

Completion:

2028-12-29

Conditions

• Breast Cancer
• HER2-positive

Interventions

• DRUG

No Results Yet

NCT05034536 | ACTIVE_NOT_RECRUITING | PHASE2

36 participants

PD-1 Antibody Therapy + Infliximab for Metastatic Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-02-07

Completion:

2027-06-30

Conditions

• Metastatic Melanoma

Interventions

• DRUG

No Results Yet

NCT05021029 | ENROLLING_BY_INVITATION

1000 participants

UC Davis Cohort of Pre-Malignant and Malignant Gastro-Intestinal DisEases Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2021-07-13

Completion:

2030-10-31

Conditions

• Intestinal Metaplasia
• Chronic Gastritis
• Atrophic Gastritis
• Autoimmune Gastritis
• Intestinal Dysplasia
• Gastric Polyps

No Results Yet

NCT05020236 | RECRUITING | PHASE3

893 participants

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-10-04

Completion:

2026-02-26

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT04989790 | RECRUITING | NA

1440 participants

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-08-08

Completion:

2025-08-11

Conditions

• Child
• Intensive Care Unit Acquired Weakness
• Critical Illness
• Hospital Acquired Pressure Ulcer

Interventions

• OTHER

No Results Yet

NCT04986631 | COMPLETED | EARLY_PHASE1

65 participants

Pharmacokinetics and Pharmacodynamics of Topiramate for Weight Loss in Youth: PHARMATOP

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-04-04

Completion:

2024-09-26

Conditions

• Obesity, Childhood

Interventions

• DRUG

Results Available

NCT04984512 | RECRUITING | PHASE2/PHASE3

600 participants

The Efficacy And Safety Of Mitizodone Phosphate Tablets In The Treatment of Patient With Major Depressive Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-12-14

Completion:

2027-07-31

Conditions

• Depressive Disorder, Major

Interventions

• DRUG

No Results Yet

NCT04973605 | RECRUITING | PHASE1/PHASE2

246 participants

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-09-16

Completion:

2026-11-30

Conditions

• Relapsed/Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT04969926 | RECRUITING

3000 participants

Natural History Study of Parathyroid Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2021-11-30

Completion:

2031-01-22

Conditions

• Parathyroid Cancer
• Primary Hyperparathyroidism
• Pseudohypoparathyroidism
• Inheritable Bone Diseases
• Multiple Endocrine Neoplasia, Type 1

No Results Yet

NCT04968288 | RECRUITING

195 participants

Natural History of KSHV-Associated Multicentric Castleman s Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2021-11-17

Completion:

2034-01-01

Conditions

• Multicentric Castleman s Disease

No Results Yet

NCT04910347 | ACTIVE_NOT_RECRUITING | PHASE2

57 participants

Consolidation Nivolumab After Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-02-07

Completion:

2031-04-30

Conditions

• Locally Advanced Nasopharyngeal Carcinoma

Interventions

• DRUG

No Results Yet

NCT04901234 | RECRUITING | PHASE2

120 participants

Adaptive RadioTherapy for OroPharynx Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-07-30

Completion:

2026-12-31

Conditions

• Oropharynx Cancer
• Radiotherapy; Complications
• Radiotherapy Side Effect
• Dysphagia
• MRI

Interventions

• RADIATION

No Results Yet

NCT04898452 | ACTIVE_NOT_RECRUITING

19 participants

Intravenous Antibiotic Treatment at Home

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2020-07-02

Completion:

2025-07-22

Conditions

• Infection

Interventions

• OTHER

No Results Yet

NCT04855656 | RECRUITING | PHASE1

464 participants

Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-04-30

Completion:

2027-12-31

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04844606 | RECRUITING | PHASE3

150 participants

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-05-26

Completion:

2030-12-31

Conditions

• Ulcerative Colitis
• Ulcerative Colitis Chronic
• Inflammatory Bowel Diseases
• Crohn's Disease

Interventions

• DRUG

No Results Yet

NCT04823663 | RECRUITING

12500 participants

BoStOn SCientific Rhythm MAnagemenT REgiStry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2021-03-31

Completion:

2030-12-31

Conditions

• Cardiac Disease

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT04815876 | COMPLETED | NA

1040 participants

PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy 2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-06-24

Completion:

2025-10-11

Conditions

• Infection

Interventions

• PROCEDURE
• DRUG

Results Available

NCT04759586 | ACTIVE_NOT_RECRUITING | PHASE3

244 participants

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-10-05

Completion:

2026-12-31

Conditions

• Primary Mediastinal Large B-Cell Lymphoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT04758962 | COMPLETED | PHASE1

10 participants

A Study of the Safety of and Immune Response to Varying Doses of a Vaccine Against COVID-19 in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-02-15

Completion:

2021-06-04

Conditions

• Virus Diseases

Interventions

• BIOLOGICAL

Results Available

NCT04704024 | ACTIVE_NOT_RECRUITING | PHASE3

334 participants

Reducing Vertical Transmission of Hepatitis B in Africa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-09-03

Completion:

2026-05-01

Conditions

• Hepatitis B Infection

Interventions

• DRUG

No Results Yet

NCT04681066 | COMPLETED | PHASE2

216 participants

A Study of Auxora in Patients With Acute Pancreatitis and Accompanying SIRS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-03-24

Completion:

2024-05-15

Conditions

• Acute Pancreatitis
• Systemic Inflammatory Response Syndrome

Interventions

• DRUG
• OTHER

Results Available

NCT04672811 | COMPLETED | NA

595 participants

Comprehensive and Continuous Status Measurement of Pre- and Post-Deployment Warfighters With Mobile Application

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-01-06

Completion:

2024-11-30

Conditions

• Military Operations
• Military Activity

Interventions

• DEVICE

No Results Yet

NCT04671667 | RECRUITING | PHASE2

188 participants

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-04-27

Completion:

2029-06-30

Conditions

• Recurrent Head and Neck Squamous Cell Carcinoma
• Recurrent Hypopharyngeal Squamous Cell Carcinoma
• Recurrent Laryngeal Squamous Cell Carcinoma
• Recurrent Oral Cavity Squamous Cell Carcinoma
• Recurrent Oropharyngeal Squamous Cell Carcinoma

Interventions

• DRUG
• PROCEDURE
• RADIATION
• BIOLOGICAL

No Results Yet

NCT04664634 | RECRUITING | PHASE3

60 participants

A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-04-01

Completion:

2026-10-31

Conditions

• Dysphagia
• Parkinson Disease

Interventions

• DEVICE

No Results Yet

NCT04663724 | RECRUITING | NA

80 participants

Computer - Based Treatment for Social Anxiety Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2021-02-15

Completion:

2026-11-30

Conditions

• Social Anxiety Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04660955 | ENROLLING_BY_INVITATION

219 participants

MOON Onsite MRI 10 Years After ACL Reconstruction

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2020-01-01

Completion:

2027-06-30

Conditions

• Osteoarthritis, Knee

Interventions

• OTHER

No Results Yet

NCT04628026 | RECRUITING | PHASE3

650 participants

Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2022-09-13

Completion:

2029-03-31

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG
• COMBINATION_PRODUCT
• OTHER

No Results Yet

NCT04616794 | COMPLETED | NA

41 participants

Intervention on Modifiable Lifestyle Risk Factors for Dementia Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2020-10-13

Completion:

2020-12-24

Conditions

• Risk Behavior
• Cognitive Decline

Interventions

• BEHAVIORAL

No Results Yet

NCT04606979 | COMPLETED | NA

30 participants

tDCS of the Primary Motor Cortex to Improve Implicit Motor Sequence Learning in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2020-10-11

Completion:

2024-02-09

Conditions

• Parkinson Disease
• Parkinson
• Healthy

Interventions

• DEVICE

No Results Yet

NCT04573062 | RECRUITING

1590 participants

Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2022-01-02

Completion:

2027-12-31

Conditions

• Post-Coronavirus Disease 19

No Results Yet