Clinical Trials

NCT07300189 | RECRUITING | PHASE1

332 participants

A Study to Evaluate Single and Multiple Doses of TLC-1180 in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-10-20

Completion:

2028-03-01

Conditions

• Healthy Participants

Interventions

• DRUG
• OTHER

No Results Yet

NCT07297979 | RECRUITING | PHASE1

50 participants

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-04-08

Completion:

2030-05-26

Conditions

• Ewing Sarcoma

Interventions

• DRUG

No Results Yet

NCT07294170 | RECRUITING

70 participants

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2025-12-19

Completion:

2028-03-07

Conditions

• Myasthenia Gravis
• MG
• gMG
• Generalized Myasthenia Gravis
• Generalized Myasthenia Gravis (gMG)
• AChR-Ab Seropositive Generalized Myasthenia Gravis

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT07288489 | RECRUITING | PHASE3

800 participants

Phase 3 Trial of VMX-C001 vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-08-18

Completion:

2029-01-31

Conditions

• Blood Loss, Surgical
• Coagulation Disorder

Interventions

• DRUG

No Results Yet

NCT07286383 | NOT_YET_RECRUITING | NA

306 participants

Testing the Use of VA Peer Specialists to Prevent Veteran Suicide

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-09-01

Completion:

2028-12-31

Conditions

• Suicide Risk

Interventions

• BEHAVIORAL

No Results Yet

NCT07285473 | NOT_YET_RECRUITING | PHASE2

75 participants

Low-Dose Naltrexone For ME/CFS: Dose-Finding

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-10-01

Completion:

2028-04-01

Conditions

• Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Interventions

• DRUG

No Results Yet

NCT07284420 | RECRUITING | PHASE2

70 participants

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-12-19

Completion:

2028-03-07

Conditions

• AChR-Ab Seropositive Generalized Myasthenia Gravis
• Myasthenia Gravis
• MG
• gMG
• Generalized Myasthenia Gravis
• Generalized Myasthenia Gravis (gMG)

Interventions

• BIOLOGICAL

No Results Yet

NCT07283497 | RECRUITING | PHASE4

30 participants

Itraconazole Therapy In Bronchiectasis With Airway Mold

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-08-17

Completion:

2030-12-31

Conditions

• Bronchiectasis
• Fungal Infection of Upper Respiratory Tract

Interventions

• DRUG

No Results Yet

NCT07282600 | RECRUITING | PHASE3

1035 participants

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-12-15

Completion:

2028-01-31

Conditions

• Overweight
• Obesity

Interventions

• DRUG

No Results Yet

NCT07277244 | ENROLLING_BY_INVITATION | NA

60 participants

Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-04-02

Completion:

2026-10-31

Conditions

• Robotic Surgery
• Post Operative Pulmonary Complications

Interventions

• DEVICE

No Results Yet

NCT07276750 | RECRUITING | NA

373 participants

Coaching and Leadership in Autism Support Settings

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-02-01

Completion:

2030-06-30

Conditions

• Autism Spectrum Disorder (ASD)

Interventions

• OTHER

No Results Yet

NCT07273617 | COMPLETED | NA

40 participants

Effects of Positive End-Expiratory Pressure (PEEP) and Prone Positioning in Healthy Volunteers on Venous Hemodynamics Including the Venous Excess Ultrasound (VExUS) Score

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-09-25

Completion:

2025-12-15

Conditions

• Venous Hemodynamics

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT07271693 | RECRUITING | PHASE1

128 participants

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-12-22

Completion:

2027-03-01

Conditions

• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT07271368 | RECRUITING | NA

25 participants

EXTERNAL NEGATIVE PRESSURE DURING LISA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-03-17

Completion:

2027-03-30

Conditions

• Neonatology

Interventions

• PROCEDURE

No Results Yet

NCT07271355 | NOT_YET_RECRUITING | PHASE3

129 participants

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-10-01

Completion:

2031-02-28

Conditions

• Metastatic Appendix Carcinoma
• Metastatic Colorectal Carcinoma
• Metastatic Malignant Neoplasm in the Peritoneum
• Stage IV Appendix Carcinoma AJCC v8
• Stage IVC Colorectal Cancer AJCC v8
• Unresectable Colorectal Carcinoma

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT07270614 | COMPLETED | NA

37 participants

Eight-week Sports Injury Prevention Program

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-02-16

Completion:

2025-11-30

Conditions

• Health Adult Subjects

Interventions

• BEHAVIORAL

No Results Yet

NCT07269730 | COMPLETED | NA

15 participants

Effects of Calcium-Containing Oral Sprays on Fluorescence-Detectable Plaque Area in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-06-11

Completion:

2024-08-05

Conditions

• Dental Caries Tooth Demineralization
• Early Childhood Caries (ECC)

Interventions

• OTHER

No Results Yet

NCT07267364 | RECRUITING | NA

48 participants

Pelvic Floor Muscle Training and Dynamic Neuromuscular Stabilization Exercises in Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-11-11

Completion:

2026-02-01

Conditions

• Urology
• Pediatric Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT07265947 | RECRUITING | PHASE2

230 participants

Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-12-22

Completion:

2030-10-31

Conditions

• Low Grade Upper Tract Urothelial Carcinoma

Interventions

• DRUG

No Results Yet

NCT07265180 | RECRUITING | NA

120 participants

Oxytocin-Augmented Group Psychotherapy for Patients With Schizophrenia - an Oxytocin-dose Comparison

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-09-08

Completion:

2026-11-30

Conditions

• Schizophrenia Spectrum Disorders (SSD)

Interventions

• OTHER

No Results Yet

NCT07261241 | NOT_YET_RECRUITING | PHASE2

118 participants

NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + Dinutuximab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-12-31

Completion:

2030-12-31

Conditions

• Neuroblastoma

Interventions

• DRUG

No Results Yet

NCT07240077 | RECRUITING | PHASE4

165 participants

Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-01-08

Completion:

2027-12-31

Conditions

• Bacteremia
• Streptococcus Infection

Interventions

• DRUG

No Results Yet

NCT07227597 | RECRUITING | PHASE1/PHASE2

170 participants

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-01-29

Completion:

2030-11-29

Conditions

• Small Cell Lung Cancer Extensive Stage

Interventions

• DRUG

No Results Yet

NCT07226128 | RECRUITING | NA

150 participants

The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-04-10

Completion:

2029-08-31

Conditions

• HIV
• Depression in Adults
• Insulin Resistance
• Cognitive Behavior Therapy

Interventions

• BEHAVIORAL

No Results Yet

NCT07225855 | RECRUITING | NA

36 participants

Geriatric Assessment and Management for Older Adults Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer and Their Family Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-10-01

Completion:

2027-11-24

Conditions

• Localized Head and Neck Carcinoma

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT07223840 | RECRUITING | PHASE2

222 participants

A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-11-03

Completion:

2027-02-28

Conditions

• Smoking

Interventions

• DRUG

No Results Yet

NCT07223593 | RECRUITING | PHASE3

1205 participants

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-10-31

Completion:

2028-06-30

Conditions

• Peripheral Arterial Disease

Interventions

• DRUG

No Results Yet

NCT07221617 | RECRUITING | PHASE4

100 participants

Oral Methadone in Cardiac Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-01-13

Completion:

2026-08-31

Conditions

• Pain, Postoperative
• Anesthesia
• Cardiac Surgery

Interventions

• DRUG

No Results Yet

NCT07221474 | RECRUITING | PHASE2

180 participants

A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-12-12

Completion:

2029-07-02

Conditions

• Squamous Non-small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG
• OTHER

No Results Yet

NCT07221253 | RECRUITING | PHASE3

1100 participants

A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-12-04

Completion:

2029-07-31

Conditions

• Biliary Tract Cancer

Interventions

• DRUG

No Results Yet

NCT07220252 | RECRUITING | PHASE2/PHASE3

240 participants

Study to Assess Effects of Ublituximab in Pediatric Participants With Relapsing Forms of Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-07-01

Completion:

2030-01-01

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT07219953 | RECRUITING | PHASE3

1100 participants

A Study of Brenipatide in Participants With Alcohol Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-10-16

Completion:

2028-04-30

Conditions

• Alcohol Use Disorder

Interventions

• DRUG

No Results Yet

NCT07219173 | RECRUITING | PHASE2

531 participants

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-10-22

Completion:

2028-04-30

Conditions

• Asthma

Interventions

• DRUG

No Results Yet

NCT07218380 | RECRUITING | PHASE3

450 participants

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-12-12

Completion:

2029-10-31

Conditions

• Carcinoma, Transitional Cell
• Urinary Bladder Neoplasms
• Neoplasm Metastasis

Interventions

• DRUG
• OTHER

No Results Yet

NCT07216560 | RECRUITING | PHASE1/PHASE2

200 participants

First-in-human Study of 7MW4911 in GI Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-01-13

Completion:

2027-07-31

Conditions

• GI Cancers

Interventions

• DRUG

No Results Yet

NCT07215559 | RECRUITING | PHASE2

200 participants

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-10-16

Completion:

2027-03-31

Conditions

• Obesity
• Overweight
• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT07215078 | COMPLETED | PHASE1

72 participants

Study About Whether Atirmociclib/PF-07220060 Proportionally Increases Exposure as Dose Increases in Healthy Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-10-08

Completion:

2026-07-21

Conditions

• Healthy Volunteer

Interventions

• DRUG

No Results Yet

NCT07214662 | TERMINATED | PHASE1

3 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-0587 as a Monotherapy and in Combination With Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-01-13

Completion:

2026-06-24

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT07213986 | RECRUITING | NA

12 participants

Vibrant Capsule for Spinal Cord Injury Neurogenic Bowel Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-01-06

Completion:

2026-08-19

Conditions

• Neurogenic Bowel Dysfunction
• Spinal Cord Injury

Interventions

• DEVICE

No Results Yet

NCT07213804 | RECRUITING | PHASE3

1630 participants

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-10-22

Completion:

2028-11-30

Conditions

• Ovarian Neoplasms
• Fallopian Tube Neoplasms
• Peritoneal Neoplasms
• Neoplasm Metastasis

Interventions

• DRUG

No Results Yet