Clinical Trials

NCT06084091 | RECRUITING

40 participants

Spectroscopic Assessment of Intramyocardial Oxygen Saturation During Open-Heart Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2023-10-06

Completion:

2026-12-31

Conditions

• Coronary Artery Disease
• Heart Valve Diseases

Interventions

• DEVICE

No Results Yet

NCT06077760 | RECRUITING | PHASE3

868 participants

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-12-06

Completion:

2030-06-25

Conditions

• Non-small Cell Lung Cancer

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06053242 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

45 participants

Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2024-05-21

Completion:

2027-01-20

Conditions

• Chronic Low-back Pain
• Degenerative Disc Disease

Interventions

• DRUG
• OTHER

No Results Yet

NCT06046729 | COMPLETED | PHASE2

352 participants

A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-10-23

Completion:

2025-09-30

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG

No Results Yet

NCT06040905 | COMPLETED | NA

51 participants

Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2024-01-24

Completion:

2026-02-12

Conditions

• Mild Cognitive Impairment
• Alzheimer Disease
• Hyperglycemia
• Pre-sarcopenia

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT06011772 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

2 participants

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-12-18

Completion:

2026-02-05

Conditions

• Colo-rectal Cancer

Interventions

• BIOLOGICAL
• DRUG
• PROCEDURE

No Results Yet

NCT05996627 | RECRUITING | PHASE2

82 participants

Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-12-06

Completion:

2028-04-30

Conditions

• Chronic Graft Versus Host Disease

Interventions

• DRUG
• PROCEDURE
• OTHER

No Results Yet

NCT05991882 | COMPLETED | NA

128 participants

Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2024-04-01

Completion:

2026-06-30

Conditions

• Alcohol Drinking
• Cannabis Use

Interventions

• BEHAVIORAL

No Results Yet

NCT05968768 | RECRUITING | PHASE2

24 participants

To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-10-24

Completion:

2027-05-01

Conditions

• Ewing Sarcoma

Interventions

• DRUG

No Results Yet

NCT05963867 | RECRUITING | PHASE1

12 participants

A Study to Test How BI 764532 is Taken up by Tumours in People With Small-cell Lung Cancer or Neuroendocrine Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2024-08-06

Completion:

2026-09-30

Conditions

• Small Cell Lung Carcinoma (SCLC)
• Neuroendocrine Neoplasms

Interventions

• DRUG

No Results Yet

NCT05944432 | ACTIVE_NOT_RECRUITING | NA

469 participants

CGM Use in Adults With Type 2 Diabetes on Basal Insulin

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-07-14

Completion:

2026-02-19

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DEVICE

No Results Yet

NCT05931913 | RECRUITING | NA

60 participants

TMS + Exposure Therapy for Pediatric OCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2024-03-20

Completion:

2029-08-31

Conditions

• Obsessive-Compulsive Disorder

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT05930561 | ACTIVE_NOT_RECRUITING | PHASE2

72 participants

4D-150 in Patients With Diabetic Macular Edema

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-08-09

Completion:

2029-02-28

Conditions

• Diabetic Macular Edema
• Diabetic Retinopathy

Interventions

• BIOLOGICAL

No Results Yet

NCT05929066 | COMPLETED | PHASE3

2335 participants

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-07-10

Completion:

2026-04-06

Conditions

• Obesity
• Overweight
• Osteoarthritis, Knee
• Obstructive Sleep Apnea

Interventions

• DRUG

No Results Yet

NCT05926011 | RECRUITING | NA

108 participants

Efficacy of RGn600 in Patients With Mild-to-moderate Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-07-24

Completion:

2027-06-30

Conditions

• Alzheimer Disease

Interventions

• DEVICE

No Results Yet

NCT05923489 | RECRUITING | NA

2618 participants

Routine Angiography Follow-Up After Percutaneous Coronary Intervention in High-Risk Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-10-26

Completion:

2028-12-30

Conditions

• Coronary Artery Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05922891 | COMPLETED

92 participants

Tezepelumab PRO Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2023-09-27

Completion:

2025-09-20

Conditions

• Asthma

No Results Yet

NCT05911451 | COMPLETED | NA

166 participants

Optimizing Access Surgery In Senior Hemodialysis Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-11-01

Completion:

2026-03-31

Conditions

• Vascular Access Complication
• Hemodialysis Access Failure
• Dialysis Access Malfunction
• Arteriovenous Fistula
• Arteriovenous Graft
• Central Venous Catheter Related Bloodstream Infection

Interventions

• PROCEDURE

No Results Yet

NCT05909748 | RECRUITING | NA

30 participants

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-05-21

Completion:

2027-12-31

Conditions

• Aortic Valve Stenosis

Interventions

• DEVICE

No Results Yet

NCT05906719 | COMPLETED

1679 participants

Machine Vision Based MDS-UPDRS III Machine Rating

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2023-03-01

Completion:

2025-12-31

Conditions

• Parkinsonian Disorders
• Machine Learning

Interventions

• OTHER

No Results Yet

NCT05897320 | RECRUITING | PHASE3

315 participants

A Study of Eptinezumab in Pediatric Participants With Episodic Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-06-08

Completion:

2027-07-06

Conditions

• Episodic Migraine

Interventions

• DRUG

No Results Yet

NCT05893940 | RECRUITING | NA

75 participants

Low-Intensity Mechanical Stimulation for Hematologic Malignancy Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-08-14

Completion:

2026-12-01

Conditions

• Hematopoietic and Lymphoid System Neoplasm

Interventions

• PROCEDURE

No Results Yet

NCT05887752 | COMPLETED | NA

74 participants

Hunova® Randomized Controlled Trial for Trunk Control Improvement in Spinal Cord Injured Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-06-05

Completion:

2026-04-05

Conditions

• Spinal Cord Injury

Interventions

• OTHER
• DEVICE

No Results Yet

NCT05878860 | RECRUITING | PHASE3

97 participants

ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-08-22

Completion:

2028-04-30

Conditions

• X-linked Retinoschisis

Interventions

• BIOLOGICAL

No Results Yet

NCT05862558 | RECRUITING

50 participants

Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2023-03-30

Completion:

2026-10-01

Conditions

• Iliac Disease
• Aortic Valve Stenosis

Interventions

• DEVICE

No Results Yet

NCT05850728 | COMPLETED | PHASE1

12 participants

First in Human Study of TLC-ART 101 (ACTU 2001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-04-01

Completion:

2024-06-28

Conditions

• Human Immunodeficiency Virus
• Treatment
• Antiretroviral Therapy

Interventions

• DRUG

Results Available

NCT05846230 | ACTIVE_NOT_RECRUITING | PHASE2

268 participants

Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-09-08

Completion:

2027-03-31

Conditions

• Bronchiectasis

Interventions

• DRUG

No Results Yet

NCT05832489 | RECRUITING | PHASE3

80 participants

EEG-MRI Imaging of Methylphenidate Effects in Adult ADHD and Attentional Symptoms in Mood Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2024-02-26

Completion:

2027-05-31

Conditions

• Adult ADHD
• Adult-onset ADHD With Mood Disorder

Interventions

• DRUG

No Results Yet

NCT05822544 | ACTIVE_NOT_RECRUITING | PHASE1

564 participants

Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-04-22

Completion:

2026-09-30

Conditions

• Healthy Subjects
• Obesity
• Type 2 Diabetes

Interventions

• DRUG
• OTHER

No Results Yet

NCT05805371 | RECRUITING | PHASE1

21 participants

PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2024-10-09

Completion:

2028-11-11

Conditions

• Castration-Resistant Prostate Carcinoma
• Metastatic Prostate Carcinoma
• Stage IVB Prostate Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• RADIATION

No Results Yet

NCT05801068 | COMPLETED | NA

2500 participants

Perioperative Management of Factor Xa Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2020-08-04

Completion:

2024-05-15

Conditions

• Atrial Fibrillation
• Anticoagulant-induced Bleeding

Interventions

• DRUG

No Results Yet

NCT05798117 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

21 participants

An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-02-28

Completion:

2026-09-24

Conditions

• Systemic Lupus Erythematosus
• Lupus Nephritis

Interventions

• DRUG

No Results Yet

NCT05797168 | RECRUITING | PHASE1/PHASE2

602 participants

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-06-05

Completion:

2028-08-04

Conditions

• Ovarian Cancer
• Lung Adenocarcinoma
• Endometrial Cancer
• Lung Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05765851 | RECRUITING | PHASE1

108 participants

A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-05-30

Completion:

2030-05-15

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05751993 | COMPLETED | NA

19 participants

Piloting a Reinforcement Learning Tool for Individually Tailoring Just-in-time Adaptive Interventions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-04-12

Completion:

2025-08-03

Conditions

• Overweight and Obesity
• Overweight
• Obesity

Interventions

• BEHAVIORAL

Results Available

NCT05740540 | ACTIVE_NOT_RECRUITING | NA

6 participants

Implant for Walking After Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-05-16

Completion:

2027-06-30

Conditions

• Stroke
• Hemiplegia
• Gait, Hemiplegic

Interventions

• DEVICE

No Results Yet

NCT05726032 | RECRUITING | PHASE2

20 participants

Empagliflozin in Patients With Cirrhosis and Ascites

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-09-11

Completion:

2026-12-01

Conditions

• Cirrhosis
• Liver Failure

Interventions

• DRUG

No Results Yet

NCT05701306 | RECRUITING | PHASE1/PHASE2

100 participants

APG-115 Alone or in Combination With APG-2575 in Recurrent or Refractory Neuroblastoma or Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-02-28

Completion:

2027-06-01

Conditions

• Neuroblastoma
• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05691374 | COMPLETED

75 participants

Evaluation of Functional and Biomechanical Outcome by Shear-wave Elastography in the Short to Intermediate Follow-up After Arthroscopic Rotator Cuff Repair

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2022-12-22

Completion:

2025-08-19

Conditions

• Arthroscopic Rotator Cuff Repair (ARCR)

Interventions

• PROCEDURE

No Results Yet

NCT05677113 | ACTIVE_NOT_RECRUITING | PHASE2

115 participants

A Study of QBECO Versus Placebo in the Treatment of Colorectal Cancer That Has Spread to the Liver

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-08-01

Completion:

2027-02-28

Conditions

• Colorectal Cancer
• Liver Metastases

Interventions

• DRUG

No Results Yet