Clinical Trials

NCT05241834 | COMPLETED | PHASE1

70 participants

A Study of LOXO-260 in Cancer Patients With a Change in a Particular Gene (RET) That Has Not Responded to Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-03-23

Completion:

2024-09-17

Conditions

• Carcinoma, Non-Small-Cell Lung
• Thyroid Neoplasms

Interventions

• DRUG

No Results Yet

NCT05236010 | RECRUITING | NA

108 participants

Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-01-21

Completion:

2026-10-01

Conditions

• Traumatic Brain Injury

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05233566 | COMPLETED | PHASE3

32 participants

Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-04-25

Completion:

2023-03-08

Conditions

• Postoperative Depression

Interventions

• DRUG

Results Available

NCT05226390 | TERMINATED | PHASE1

23 participants

Safety, Reactogenicity and Immunogenicity of a Novel MVA-SARS-2-ST Vaccine Candidate

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-02-24

Completion:

2023-11-17

Conditions

• COVID-19 Vaccines

Interventions

• BIOLOGICAL

No Results Yet

NCT05226078 | ACTIVE_NOT_RECRUITING | NA

64 participants

The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-03-01

Completion:

2026-08-31

Conditions

• Chronic Insomnia
• Cancer-related Problem/Condition
• Cancer-Related Syndrome

Interventions

• BEHAVIORAL

No Results Yet

NCT05212246 | NOT_YET_RECRUITING | PHASE3

1630 participants

Basal Cell Carcinoma Chemoprevention Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2026-09-21

Completion:

2032-09-21

Conditions

• Basal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05207878 | COMPLETED | NA

120 participants

Interhemispheric Connectivity and Compensation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-12-09

Completion:

2025-08-01

Conditions

• Peripheral Nerve Injury Upper Limb
• Healthy

Interventions

• OTHER

No Results Yet

NCT05205343 | RECRUITING

20 participants

Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2022-05-11

Completion:

2028-05-31

Conditions

• Gastrostomy
• Gastric
• GastroEsophageal Cancer

Interventions

• OTHER

No Results Yet

NCT05197270 | RECRUITING | PHASE1/PHASE2

215 participants

4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-12-09

Completion:

2027-03-31

Conditions

• Neovascular (Wet) Age-Related Macular Degeneration

Interventions

• BIOLOGICAL

No Results Yet

NCT05197023 | COMPLETED | PHASE1

21 participants

A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF MULTIPLE SUBCUTANEOUS INJECTIONS OF SHR-1819 IN PATIENTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-01-30

Completion:

2022-10-27

Conditions

• Moderate to Severe Atopic Dermatitis

Interventions

• DRUG

No Results Yet

NCT05189262 | ACTIVE_NOT_RECRUITING

111 participants

Cardiopulmonary Bypass Induced Red Blood Cell Lysis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2022-03-22

Completion:

2027-12-31

Conditions

• Cardiopulmonary Bypass
• Cardiac Surgery
• Kidney Injury, Acute

Interventions

• OTHER

No Results Yet

NCT05179369 | ACTIVE_NOT_RECRUITING | NA

576 participants

Well-Mama Community Doula Navigator Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2023-05-07

Completion:

2027-06-30

Conditions

• Pregnancy Related

Interventions

• BEHAVIORAL

No Results Yet

NCT05156710 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

BIVV020 (SAR445088) in Prevention and Treatment of Antibody-mediated Rejection (AMR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-06-09

Completion:

2025-10-21

Conditions

• Transplant Rejection

Interventions

• DRUG

No Results Yet

NCT05154331 | COMPLETED

5500 participants

Antenatal and Postnatal Care Research Collective - Household Survey (ARCH)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2022-03-29

Completion:

2025-12-31

Conditions

• Maternal Health
• Pregnancy Outcomes

No Results Yet

NCT05148494 | RECRUITING | PHASE4

66 participants

TES RCT Fleet Enema vs Oral Mechanical Bowel Prep

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-03-16

Completion:

2027-08-01

Conditions

• Colorectal Neoplasms
• Surgery

Interventions

• DRUG

No Results Yet

NCT05126277 | ACTIVE_NOT_RECRUITING | PHASE3

452 participants

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-07-14

Completion:

2027-09-21

Conditions

• Lupus Nephritis

Interventions

• DRUG

No Results Yet

NCT05114980 | WITHDRAWN | NA

0 participants

Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2027-07-31

Completion:

2029-01-31

Conditions

• Hypoparathyroidism

Interventions

• PROCEDURE

No Results Yet

NCT05110638 | COMPLETED | PHASE1

19 participants

Safety and Tolerability Study of SKX-16 in Subjects With Moderate to Severe Distal Subungual Onychomycosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-09-22

Completion:

2022-05-30

Conditions

• Onychomycosis of Toenail

Interventions

• DRUG

No Results Yet

NCT05084768 | RECRUITING

150 participants

Dd-cfDNA and Treg in Prediction of Kidney Transplant Acute Rejection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2020-12-07

Completion:

2026-10-01

Conditions

• Acute Rejection of Renal Transplant
• Graft Failure

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05072483 | RECRUITING

155 participants

Natural History Study of CADASIL

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2022-04-18

Completion:

2034-06-01

Conditions

• Cardiovascular Disease
• Arterial Stiffness
• Germline Mutation in the NOTCH 3 Gene
• Pathogenesis of CADASIL
• Clinical Phenotype of CADASIL

Interventions

• DEVICE

No Results Yet

NCT05066217 | RECRUITING | PHASE3

260 participants

An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2025-04-09

Completion:

2026-11-01

Conditions

• Lennox Gastaut Syndrome

Interventions

• DRUG

No Results Yet

NCT05065216 | RECRUITING | PHASE2/PHASE3

728 participants

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-11-07

Completion:

2026-12-31

Conditions

• Acute Stroke
• Ischemic Stroke
• Stroke

Interventions

• DRUG
• OTHER

No Results Yet

NCT05062031 | COMPLETED | NA

116 participants

Myopia Control in Children: Comparison of Defocus Incorporated Multiple Segments® Lenses Versus Atropine 0.05% Eyedrops

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-10-19

Completion:

2026-02-11

Conditions

• Myopia

Interventions

• DEVICE
• DRUG

No Results Yet

NCT05061550 | RECRUITING | PHASE2

630 participants

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2022-04-14

Completion:

2030-05-28

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05047224 | COMPLETED | NA

664 participants

Addressing Disparities in Autism Spectrum Disorder Diagnosis Using a Direct-to-home Telemedicine Tool

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-12-03

Completion:

2026-03-10

Conditions

• Autism Spectrum Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05038735 | ACTIVE_NOT_RECRUITING | PHASE3

210 participants

Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-positive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-12-17

Completion:

2027-01-28

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05006716 | RECRUITING | PHASE1/PHASE2

645 participants

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-09-13

Completion:

2026-11-30

Conditions

• B-cell Malignancy
• Marginal Zone Lymphoma
• Follicular Lymphoma
• Non-Hodgkin Lymphoma
• Waldenström Macroglobulinemia
• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma
• Mantle Cell Lymphoma
• Diffuse Large B Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT05002998 | COMPLETED | PHASE4

313 participants

TEPEZZA® (Teprotumumab-trbw) Post-Marketing Requirement Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-09-16

Completion:

2025-12-19

Conditions

• Thyroid Eye Disease

Interventions

• DRUG

No Results Yet

NCT04965675 | RECRUITING | PHASE3

285 participants

A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-06-30

Completion:

2026-09-05

Conditions

• Chronic Migraine in Children

Interventions

• DRUG

No Results Yet

NCT04949256 | TERMINATED | PHASE3

863 participants

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014).

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-07-28

Completion:

2025-05-08

Conditions

• Metastatic Esophageal Squamous Cell Carcinoma

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04947462 | RECRUITING | NA

8 participants

Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-12-01

Completion:

2030-05-31

Conditions

• Upper Limb Amputees

Interventions

• DEVICE

No Results Yet

NCT04943211 | RECRUITING | PHASE3

150 participants

Determination of Molecular Status, the Efficacy and Safety of Fluorodeoxyglucose in PET-CT Imaging

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-04-01

Completion:

2027-06-30

Conditions

• Histiocytosis

Interventions

• DRUG

No Results Yet

NCT04876053 | COMPLETED | NA

416 participants

Home Food Delivery for Diabetes Management in Patients of Rural Clinics

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-10-22

Completion:

2025-02-06

Conditions

• Diabetes Mellitus, Type 2
• Diet, Healthy

Interventions

• BEHAVIORAL

Results Available

NCT04849741 | ACTIVE_NOT_RECRUITING | PHASE3

54 participants

A Study to Evaluate the Safety and Efficacy of Zilganersen (ION373) in Patients With Alexander Disease (AxD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-06-01

Completion:

2025-08-22

Conditions

• Alexander Disease

Interventions

• DRUG

No Results Yet

NCT04788004 | COMPLETED

733 participants

Long-term Recovery: Longitudinal Study of Neuro-behavioral Markers of Recovery and Precipitants of Relapse

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2022-09-08

Completion:

2026-07-14

Conditions

• Alcohol Use Disorder

Interventions

• OTHER

No Results Yet

NCT04754412 | ACTIVE_NOT_RECRUITING | NA

256 participants

Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stage 0-III Breast Cancer Survivors, Writing to Heal Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-07-23

Completion:

2028-04-01

Conditions

• Anatomic Stage 0 Breast Cancer AJCC v8
• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage IA Breast Cancer AJCC v8
• Anatomic Stage IB Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage IIA Breast Cancer AJCC v8
• Anatomic Stage IIB Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Anatomic Stage IIIB Breast Cancer AJCC v8
• Anatomic Stage IIIC Breast Cancer AJCC v8
• Prognostic Stage 0 Breast Cancer AJCC v8
• Prognostic Stage I Breast Cancer AJCC v8
• Prognostic Stage IA Breast Cancer AJCC v8
• Prognostic Stage IB Breast Cancer AJCC v8
• Prognostic Stage II Breast Cancer AJCC v8
• Prognostic Stage IIA Breast Cancer AJCC v8
• Prognostic Stage IIB Breast Cancer AJCC v8
• Prognostic Stage III Breast Cancer AJCC v8
• Prognostic Stage IIIA Breast Cancer AJCC v8
• Prognostic Stage IIIB Breast Cancer AJCC v8
• Prognostic Stage IIIC Breast Cancer AJCC v8

Interventions

• OTHER

No Results Yet

NCT04728893 | RECRUITING | PHASE2

490 participants

Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-04-05

Completion:

2029-01-04

Conditions

• Hematologic Malignancies
• Waldenstroms Macroglobulinaemia
• Non-Hodgkins Lymphoma
• Chronic Lymphocytic Leukaemia

Interventions

• DRUG

No Results Yet

NCT04726800 | ACTIVE_NOT_RECRUITING

300 participants

Circulating Tumour DNA (ctDNA) as a Prognostic and Predictive Marker in Colorectal Cancer - a Pilot Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2020-10-01

Completion:

2026-12-31

Conditions

• Colorectal Cancer

No Results Yet

NCT04724668 | COMPLETED | NA

84 participants

The Role of the Circadian System in Binge Eating Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-01-15

Completion:

2025-05-30

Conditions

• Binge-Eating Disorder
• Circadian Rhythm Disorders

Interventions

• DIETARY_SUPPLEMENT
• DEVICE

Results Available

NCT04699123 | ACTIVE_NOT_RECRUITING | PHASE2

159 participants

The Study of NC318 Alone or in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-02-04

Completion:

2026-12-30

Conditions

• Advanced Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet