Clinical Trials

NCT03992404 | ACTIVE_NOT_RECRUITING | PHASE3

603 participants

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-09-16

Completion:

2025-06-19

Conditions

• Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury

Interventions

• DRUG

No Results Yet

NCT03969329 | RECRUITING | PHASE3

24 participants

A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-12-20

Completion:

2027-06-30

Conditions

• Secondary Hyperparathyroidism

Interventions

• DRUG

No Results Yet

NCT03965234 | RECRUITING | PHASE1/PHASE2

99 participants

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2020-07-16

Completion:

2029-05-25

Conditions

• Metastatic Bone Sarcoma
• Metastatic Malignant Neoplasm in the Lung
• Metastatic Soft Tissue Sarcoma
• Metastatic Unresectable Sarcoma
• Resectable Sarcoma
• Colorectal Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03962569 | COMPLETED

25 participants

Early Activation of Artificial Urinary Sphincter

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2019-08-01

Completion:

2023-10-31

Conditions

• Incontinence, Urinary

No Results Yet

NCT03940703 | COMPLETED | PHASE2

140 participants

A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-09-19

Completion:

2023-05-11

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT03921541 | COMPLETED | PHASE3

32 participants

Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-05-01

Completion:

2023-02-01

Conditions

• Arginase I Deficiency
• Hyperargininemia

Interventions

• DRUG

Results Available

NCT03899025 | COMPLETED | NA

91 participants

Diagnostics of Scaphoid Fractures With HRpQCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-12-12

Completion:

2019-11-28

Conditions

• Scaphoid Fracture
• Scafoïd; Fracture

Interventions

• RADIATION

No Results Yet

NCT03890601 | COMPLETED

74 participants

New Biological Tests in Patients With Antiphospholipid Antibodies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2019-03-13

Completion:

2023-05-22

Conditions

• Antiphospholipid Syndrome

Interventions

• BIOLOGICAL

No Results Yet

NCT03884998 | ACTIVE_NOT_RECRUITING | PHASE1

27 participants

Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-07-10

Completion:

2026-11-04

Conditions

• Chronic Lymphocytic Leukemia
• Diffuse Large B-Cell Lymphoma
• Follicular Lymphoma
• Indolent Non-Hodgkin Lymphoma
• Lymphoplasmacytic Lymphoma
• Marginal Zone Lymphoma
• Richter Syndrome

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03876314 | COMPLETED | NA

180 participants

Physical Activity, Alzheimer's Disease and Cognition Relative to APOE Genotype

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-05-23

Completion:

2024-12-21

Conditions

• Healthy
• Dementia
• Alzheimer Disease
• Physical Activity

Interventions

• BEHAVIORAL

Results Available

NCT03842007 | RECRUITING | NA

160 participants

Understanding Mechanisms of Normal and Disordered Defecation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-01-29

Completion:

2028-12-31

Conditions

• Constipation

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03764553 | ACTIVE_NOT_RECRUITING | PHASE2

320 participants

Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-05-01

Completion:

2025-07-31

Conditions

• Esophageal Cancer

Interventions

• DRUG

No Results Yet

NCT03740334 | ACTIVE_NOT_RECRUITING | PHASE1

45 participants

Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-01-30

Completion:

2023-03-04

Conditions

• Acute Lymphoblastic Leukemia ALL

Interventions

• DRUG

No Results Yet

NCT03728335 | SUSPENDED | PHASE2

35 participants

Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-12-23

Completion:

2027-01-11

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT03705416 | ACTIVE_NOT_RECRUITING

250 participants

Long Term Outcomes of Bariatric Patients Treated With Surgery or Endoscopy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2019-03-30

Completion:

2026-12-31

Conditions

• GERD
• Obesity

Interventions

• PROCEDURE

No Results Yet

NCT03663361 | COMPLETED | NA

43 participants

Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-11-12

Completion:

2026-05-06

Conditions

• Ankle Sprains

Interventions

• OTHER

No Results Yet

NCT03655002 | ACTIVE_NOT_RECRUITING | PHASE1

8 participants

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-05-17

Completion:

2027-03-02

Conditions

• Recurrent Hepatocellular Carcinoma
• Refractory Liver Carcinoma
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03589846 | ENROLLING_BY_INVITATION | NA

60 participants

Muscle Stimulation During DISE

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2018-07-26

Completion:

2028-12-31

Conditions

• Obstructive Sleep Apnea

Interventions

• DEVICE

No Results Yet

NCT03567213 | RECRUITING | NA

3 participants

Investigation on the Cortical Communication (CortiCom) System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2021-12-14

Completion:

2028-12-31

Conditions

• Tetraplegia
• Locked-in Syndrome
• Brainstem Stroke
• Amyotrophic Lateral Sclerosis

Interventions

• DEVICE

No Results Yet

NCT03538639 | RECRUITING

1000 participants

Vascular Disease Discovery Protocol

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2018-07-30

Completion:

2027-11-30

Conditions

• Vascular Dysfunction
• Genetic Mutations
• Genetic Predisposition

No Results Yet

NCT03530397 | ACTIVE_NOT_RECRUITING | PHASE1

400 participants

A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2018-04-24

Completion:

2025-07-14

Conditions

• Selected Advanced Solid Tumors

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03504956 | RECRUITING | NA

150 participants

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2018-07-30

Completion:

2027-06-30

Conditions

• Coronary Atherosclerosis

Interventions

• DEVICE
• DRUG

No Results Yet

NCT03492372 | ENROLLING_BY_INVITATION

300 participants

Molecular Characterization of Spinal Tissue

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2015-03-31

Completion:

2027-07-31

Conditions

• Spinal Diseases

Interventions

• OTHER

No Results Yet

NCT03417544 | COMPLETED | PHASE2

19 participants

Atezolizumab + Pertuzumab + Trastuzumab In CNS Mets In BC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2018-05-21

Completion:

2020-05-20

Conditions

• HER2-positive Metastatic Breast Cancer
• Central Nervous System Metastases

Interventions

• DRUG

Results Available

NCT03301792 | ACTIVE_NOT_RECRUITING | NA

117 participants

Group Versus Traditional Prenatal Care for Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-09-14

Completion:

2025-11-17

Conditions

• Pregnancy
• Gestational Diabetes
• Type 2 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT03208868 | RECRUITING | NA

32 participants

Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2013-08-05

Completion:

2028-12-31

Conditions

• Cirrhosis, Liver

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT03188432 | COMPLETED | PHASE2

50 participants

Hyperthermic Intraperitoneal Chemotherapy Trial Comparing Quality of Life in Patients With Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2019-01-02

Completion:

2024-01-31

Conditions

• Stage IIIC Fallopian Tube Cancer
• Stage IIIC Ovarian Cancer
• Stage IIIC Primary Peritoneal Cancer
• Stage IV Fallopian Tube Cancer
• Stage IV Ovarian Cancer
• Stage IV Primary Peritoneal Cancer

Interventions

• DRUG
• OTHER
• PROCEDURE

Results Available

NCT03161067 | RECRUITING | NA

5 participants

Investigation on the Bidirectional Cortical Neuroprosthetic System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-08-01

Completion:

2028-12-31

Conditions

• Tetraplegia
• Quadriplegia

Interventions

• DEVICE

No Results Yet

NCT03150329 | ACTIVE_NOT_RECRUITING | PHASE1

52 participants

Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-07-18

Completion:

2023-06-23

Conditions

• Grade 3b Follicular Lymphoma
• Recurrent B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between DLBCL and Classic HL
• Recurrent Classic Hodgkin Lymphoma
• Recurrent Diffuse Large B-Cell Lymphoma
• Recurrent Follicular Lymphoma
• Recurrent Grade 1 Follicular Lymphoma
• Recurrent Grade 2 Follicular Lymphoma
• Recurrent Grade 3a Follicular Lymphoma
• Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma
• Recurrent Transformed Non-Hodgkin Lymphoma
• Refractory B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between DLBCL and Classic HL
• Refractory Classic Hodgkin Lymphoma
• Refractory Diffuse Large B-Cell Lymphoma
• Refractory Follicular Lymphoma
• Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma
• Refractory Transformed Non-Hodgkin Lymphoma

Interventions

• OTHER
• BIOLOGICAL
• DRUG

Results Available

NCT03118492 | ACTIVE_NOT_RECRUITING | PHASE1

22 participants

Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Secondary Myelofibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-06-21

Completion:

2027-04-29

Conditions

• Secondary Myelofibrosis

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER
• RADIATION

No Results Yet

NCT03113500 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-05-25

Completion:

2021-07-16

Conditions

• Adult T-Cell Leukemia/Lymphoma
• Anaplastic Large Cell Lymphoma, ALK-Negative
• Anaplastic Large Cell Lymphoma, ALK-Positive
• Angioimmunoblastic T-Cell Lymphoma
• Ann Arbor Stage II Noncutaneous Anaplastic Large Cell Lymphoma
• Ann Arbor Stage III Noncutaneous Anaplastic Large Cell Lymphoma
• Ann Arbor Stage IV Noncutaneous Anaplastic Large Cell Lymphoma
• Enteropathy-Associated T-Cell Lymphoma
• Hepatosplenic T-Cell Lymphoma
• Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
• Peripheral T-Cell Lymphoma, Not Otherwise Specified

Interventions

• DRUG
• OTHER

Results Available

NCT03012789 | COMPLETED | NA

30 participants

Surgical Intervention and the NETest

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-05-15

Completion:

2025-12-01

Conditions

• Neuroendocrine Tumor
• Gastroenteropancreatic

Interventions

• PROCEDURE

No Results Yet

NCT02962414 | ACTIVE_NOT_RECRUITING | PHASE3

206 participants

Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-08-23

Completion:

2026-12-30

Conditions

• Tuberous Sclerosis Complex

Interventions

• DRUG

No Results Yet

NCT02923180 | ACTIVE_NOT_RECRUITING | PHASE2

33 participants

Neoadjuvant Enoblituzumab (MGA271) in Men With Localized Intermediate and High-Risk Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2017-02-14

Completion:

2020-08-11

Conditions

• Prostate Cancer

Interventions

• DRUG

Results Available

NCT02830308 | RECRUITING

1250 participants

Evaluation of Adults With Endocrine and Metabolic-Related Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-21

Start Date:

2016-07-09

Completion:

2029-12-20

Conditions

• Endocrine Diseases

No Results Yet

NCT02763059 | COMPLETED | PHASE4

132 participants

Comparison Between Dexamethasone and Ibuprofen on Pain Prevention and Control Following Surgical Implant Placement

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2013-09-30

Completion:

2015-05-31

Conditions

• Pain Measurement

Interventions

• DRUG

Results Available

NCT02716246 | RECRUITING | PHASE2/PHASE3

36 participants

Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2016-04-25

Completion:

2029-03-31

Conditions

• MPS IIIA
• Sanfilippo Syndrome
• Sanfilippo A
• Mucopolysaccharidosis III

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT02703220 | RECRUITING | PHASE4

100 participants

Sleep Apnea in Elderly

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2015-07-03

Completion:

2027-07-30

Conditions

• Sleep Apnea
• Elderly Adults

Interventions

• OTHER
• DRUG

No Results Yet

NCT02699697 | COMPLETED | NA

102 participants

Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2016-05-31

Completion:

2025-03-20

Conditions

• Malignant Neoplasm
• Metastatic Malignant Neoplasm in the Bone
• Pain

Interventions

• RADIATION
• OTHER

Results Available

NCT02667418 | TERMINATED | PHASE4

308 participants

Optimal Treatment for Recurrent Clostridium Difficile

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-21

Start Date:

2016-02-19

Completion:

2024-08-07

Conditions

• Clostridium
• Difficile
• Fidaxomicin
• Vancomycin

Interventions

• DRUG

Results Available