Clinical Trials

NCT07191717 | RECRUITING | PHASE2

42 participants

Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Residual Disease, MIRI Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-05-18

Completion:

2030-04-30

Conditions

• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• Invasive Breast Carcinoma
• Localized Estrogen Receptor-Positive Breast Carcinoma
• Localized Human Epidermal Growth Factor Receptor (HER2)-Negative Breast Carcinoma

Interventions

• DRUG
• PROCEDURE
• OTHER

No Results Yet

NCT07187778 | RECRUITING | PHASE2

10 participants

Phase II Trial of Single Agent Belzutifan or Pembrolizumab Versus Combination as Neoadjuvant Therapy in Clear Cell Renal Cell Carcinoma (BLAZE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-12-19

Completion:

2027-07-19

Conditions

• Clear Cell Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT07184996 | RECRUITING | PHASE3

980 participants

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-10-08

Completion:

2028-05-09

Conditions

• Ulcerative Colitis

Interventions

• DRUG

No Results Yet

NCT07177846 | NOT_YET_RECRUITING | NA

80 participants

LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol for Patients Living With Metastatic Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-09-15

Completion:

2027-06-01

Conditions

• Survivorship

Interventions

• BEHAVIORAL

No Results Yet

NCT07175428 | RECRUITING | PHASE2

1200 participants

Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-10-20

Completion:

2027-02-09

Conditions

• Atrial Fibrillation (AF)

Interventions

• DRUG

No Results Yet

NCT07170917 | RECRUITING | PHASE2

208 participants

Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-11-06

Completion:

2027-02-09

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG

No Results Yet

NCT07152028 | COMPLETED | NA

34 participants

Exercise Supervision Duration and Adherence in Obese Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-09-23

Completion:

2023-12-18

Conditions

• Obesity (Disorder)

Interventions

• OTHER

No Results Yet

NCT07146802 | RECRUITING | NA

51 participants

Personalized Metacognitive Training for Psychosis: A Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-04-03

Completion:

2027-04-01

Conditions

• Schizophrenia Spectrum Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT07146581 | NOT_YET_RECRUITING | NA

40 participants

Technology-Based Intervention Pilot Testing

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-09-15

Completion:

2026-12-31

Conditions

• Dementia
• Elder Abuse
• Elder Neglect

Interventions

• BEHAVIORAL

No Results Yet

NCT07145580 | COMPLETED

510 participants

Combined Lactulose H2-breath Test With Abdominal Imaging

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2025-08-01

Completion:

2025-12-31

Conditions

• Food Intolerance Syndromes
• Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
• Breath Tests

No Results Yet

NCT07141355 | RECRUITING | NA

24 participants

Empagliflozin's Microcirculatory Effects in Cardiogenic Shock: an Ancillary Pilot Study of the EMPASHOCK Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-12-12

Completion:

2027-08-31

Conditions

• Cardiogenic Shock

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT07137481 | NOT_YET_RECRUITING | PHASE2

70 participants

Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2027-02-28

Completion:

2030-07-31

Conditions

• Hematological Malignancies

Interventions

• DRUG

No Results Yet

NCT07133425 | RECRUITING | PHASE2

29 participants

A Phase 2 Platform Study of Immunomodulatory Compounds in ICI-refractory Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-11-06

Completion:

2028-02-01

Conditions

• Non-Small Cell Lung Cancer
• ICI-refractory

Interventions

• DRUG

No Results Yet

NCT07129993 | RECRUITING | PHASE2/PHASE3

630 participants

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-09-26

Completion:

2029-06-01

Conditions

• Urothelial Cancer
• Bladder Cancer

Interventions

• DRUG

No Results Yet

NCT07126951 | NOT_YET_RECRUITING | NA

40 participants

Pilot Study: Clinical Trial of Ultrasound Guiding Pharmacopuncture Therapy for Acute Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-09-01

Completion:

2027-12-30

Conditions

• Low Back Pain (LBP)

Interventions

• PROCEDURE

No Results Yet

NCT07123090 | RECRUITING | PHASE2

25 participants

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-11-24

Completion:

2027-10-01

Conditions

• Metastatic Renal Cell Carcinoma
• Metastatic Renal Cancer
• Renal Cell Carcinoma
• Advanced Clear Cell Renal Cell Carcinoma
• Kidney Cancer
• Translocation Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT07112378 | RECRUITING | PHASE3

20 participants

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-11-10

Completion:

2028-06-19

Conditions

• Eosinophilic Esophagitis (EoE)

Interventions

• DRUG

No Results Yet

NCT07111078 | RECRUITING | PHASE1

56 participants

Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and Without ALFQ Adjuvant in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-08-27

Completion:

2027-08-18

Conditions

• Influenza Prevention
• Pandemic Influenza Prevention

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT07108335 | NOT_YET_RECRUITING | NA

404 participants

Provider and Patient RCT PROMOTE

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-10-01

Completion:

2028-08-31

Conditions

• Maternal Health
• Pregnancy
• Employment

Interventions

• OTHER

No Results Yet

NCT07107945 | RECRUITING | PHASE3

120 participants

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-12-09

Completion:

2027-04-16

Conditions

• Chronic Kidney Disease

Interventions

• DRUG

No Results Yet

NCT07101432 | RECRUITING | PHASE1

33 participants

Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-12-19

Completion:

2027-12-31

Conditions

• Head and Neck Cancer

Interventions

• DRUG

No Results Yet

NCT07098520 | ACTIVE_NOT_RECRUITING

100 participants

Biomarkers of Steatohepatitis in Type 2 Diabetes Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2024-04-18

Completion:

2028-12-30

Conditions

• Diabetes
• Steatosis of Liver

Interventions

• OTHER

No Results Yet

NCT07083765 | NOT_YET_RECRUITING | PHASE3

202 participants

Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-10-31

Completion:

2028-05-31

Conditions

• Hypertension
• Hypertension,Essential

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT07079969 | NOT_YET_RECRUITING | NA

30 participants

Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-09-30

Completion:

2027-09-30

Conditions

• Chronic Knee Pain

Interventions

• DEVICE

No Results Yet

NCT07077239 | RECRUITING

200 participants

Prostate Cancer Postoperative Stereotactic Body Radiotherapy With Adaptive Technology for Minimizing Toxicity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2025-07-17

Completion:

2035-08-01

Conditions

• Prostate Cancer (CRPC)

No Results Yet

NCT07076186 | RECRUITING | PHASE2

48 participants

Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-10-02

Completion:

2027-12-02

Conditions

• Uterine Leiomyosarcoma

Interventions

• DRUG

No Results Yet

NCT07072598 | WITHDRAWN | NA

0 participants

Comparing Efficiency and Stone-Free Rates Mini PCNL vs Flex URS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-04-30

Completion:

2027-07-31

Conditions

• Kidney Stones
• Nephrolithiasis
• Urolithiasis

Interventions

• DEVICE

No Results Yet

NCT07067736 | RECRUITING | NA

15 participants

Cefazolin Antibiotic Prophylaxis in Ventricular Shunt Surgery: Determination of Cerebrospinal Fluid Concentration During Valve Implantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-02-01

Completion:

2026-08-30

Conditions

• Hydrocephaly
• CSF Shunts
• Antibiotic Prophylaxis

Interventions

• OTHER

No Results Yet

NCT07067398 | RECRUITING | NA

40 participants

Improving the Heart Health of Home Health Aides

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-09-09

Completion:

2026-10-31

Conditions

• Cardiovascular
• Cardiovascular (CV) Risk
• Cardiovascular Disease (CVD) Risk Factors
• Cardiovascular Health

Interventions

• BEHAVIORAL

No Results Yet

NCT07060417 | NOT_YET_RECRUITING | PHASE2

52 participants

Vascular Effects of SGLT2i in Non-diabetic CKD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-10-01

Completion:

2029-03-31

Conditions

• Non-diabetic Chronic Kidney Disease

Interventions

• DRUG

No Results Yet

NCT07059988 | RECRUITING | NA

40 participants

Endogenous Energy Production in Critically Ill Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-07-14

Completion:

2027-12-31

Conditions

• Critical Illness
• Metabolism and Nutrition Disorder

Interventions

• OTHER
• DIETARY_SUPPLEMENT

No Results Yet

NCT07052994 | WITHDRAWN | PHASE1

0 participants

A Phase Ia/Ib Trial of Revumenib Combined With Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin (GO) in Frontline and Relapsed /Refractory Pediatric Acute Leukemia Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-05-21

Completion:

2026-05-21

Conditions

• Pediatric Acute Leukemia

Interventions

• DRUG

No Results Yet

NCT07042893 | COMPLETED

33 participants

Effects of Pulmonary Resection on Right Ventricular Function

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2025-04-01

Completion:

2026-04-24

Conditions

• Pulmonary Resection
• Right Ventricular Function
• Echocardiography
• Cardiothoracic Anesthesia

No Results Yet

NCT07030426 | RECRUITING | PHASE3

180 participants

Vaginal Estrogen for Improvement of Outcomes Following Pelvic Organ Prolapse Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-01-01

Completion:

2027-09-30

Conditions

• Pelvic Organ Prolapse (POP)

Interventions

• DRUG

No Results Yet

NCT07021989 | RECRUITING | PHASE2

38 participants

ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-08-18

Completion:

2029-07-31

Conditions

• Hodgkin Lymphoma, Adult
• Refractory Hodgkin Lymphoma
• Classic Hodgkin Lymphoma

Interventions

• DRUG
• RADIATION
• DEVICE
• PROCEDURE

No Results Yet

NCT07016906 | RECRUITING | NA

36 participants

MRI Assessment of Knee Kinematics From Extension to Flexion - Exploratory Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-07-08

Completion:

2026-09-30

Conditions

• Healthy Volunteer

Interventions

• OTHER

No Results Yet

NCT07015177 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2026-08-20

No Results Yet

NCT07014176 | COMPLETED | PHASE4

84 participants

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-07-03

Completion:

2026-06-15

Conditions

• Diabetic Foot Ulcer

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT07012044 | RECRUITING | PHASE1

47 participants

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-06-09

Completion:

2027-03-31

Conditions

• Acute Myeloid Leukemia Post Cytotoxic Therapy
• Recurrent Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT07011355 | COMPLETED | NA

66 participants

Effect of Stress Ball Use on Labor Pain and Birth Experience in Primiparous Women During Labor

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2025-09-20

Completion:

2025-12-30

Conditions

• Examine the Effect of Stress Ball Use During the Intrapartum Period on Labor Pain and Childbirth Experience in Primiparous Women

Interventions

• OTHER

No Results Yet