Clinical Trials Updated in 2026

NCT05360160 | RECRUITING | PHASE1/PHASE2

43 participants

A Phase I-II Study Investigating the All-Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-10-14
Completion:: 2026-12-01

Conditions

Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT05357144 | TERMINATED | NA

157 participants

AmbassADDOrs for Health Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-07-26
Completion:: 2023-12-31

Conditions

HIV Infections

Interventions

BEHAVIORAL

Results Available

NCT05354726 | COMPLETED

16 participants

Skeletal and Respiratory Muscle Strength, Pulmonary Function, Exercise Capacity and Physical Activity in Pediatric Chronic Kidney Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-03-07
Completion:: 2023-11-07

Conditions

Chronic Kidney Diseases

Interventions

OTHER

No Results Yet

NCT05338697 | RECRUITING

657 participants

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-06-18
Completion:: 2027-01-31

Conditions

Stroke
Stroke, Acute
Stroke, Ischemic

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05335928 | RECRUITING | PHASE3

390 participants

Abatacept in Immune Checkpoint Inhibitor Myocarditis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-07-02
Completion:: 2029-04-09

Conditions

Myocarditis Acute
Cancer

Interventions

DRUG

No Results Yet

NCT05335811 | RECRUITING | PHASE1

55 participants

First-in-Human Assessment of Safety, Biodistribution and Pharmacokinetics of 18F-Fluoro-1-Naphthol (18F-4FN) for PET Imaging

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-10-06
Completion:: 2028-08-31

Conditions

Endocrine Neoplasia

Interventions

DRUG

No Results Yet

NCT05327010 | RECRUITING | PHASE2

88 participants

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-11-14
Completion:: 2026-12-31

Conditions

Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm
Unresectable Malignant Solid Neoplasm

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05325996 | COMPLETED | NA

53 participants

Evaluating Home Testing Devices for the Management of Glaucoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-04-15
Completion:: 2026-08-17

Conditions

Glaucoma, Open-Angle

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05324280 | COMPLETED | NA

45 participants

Acupuncture in a Multidisciplinary Approach for Vulvodynia and Chronic Pelvic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-06-23
Completion:: 2026-01-30

Conditions

Vulvodynia
Chronic Pelvic Pain

Interventions

PROCEDURE

No Results Yet

NCT05316584 | ACTIVE_NOT_RECRUITING | NA

123 participants

A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-09-06
Completion:: 2026-12-31

Conditions

Inflammatory Bowel Diseases
Crohn Disease
Ulcerative Colitis

Interventions

BEHAVIORAL

No Results Yet

NCT05305547 | COMPLETED | PHASE3

2093 participants

A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-08-03
Completion:: 2024-01-07

Conditions

SARS-CoV-2 Infection

Interventions

DRUG

Results Available

NCT05296837 | COMPLETED | PHASE4

46 participants

Ocular Rosacea Biome Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2023-06-22
Completion:: 2025-07-14

Conditions

Ocular Rosacea
Antimicrobial Resistance

Interventions

DRUG

No Results Yet

NCT05285917 | RECRUITING | PHASE3

400 participants

Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2023-11-15
Completion:: 2026-09-01

Conditions

Sickle Cell Anemia in Children
Sickle Cell Disease

Interventions

DRUG

No Results Yet

NCT05285007 | RECRUITING | NA

60 participants

Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-03-02
Completion:: 2027-05-31

Conditions

Patellofemoral Pain

Interventions

OTHER

No Results Yet

NCT05276011 | NOT_YET_RECRUITING | PHASE2

255 participants

A Study to Determine the Safety and Efficacy of TG-C in Subjects With Symptomatic Early Hip Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2027-10-31
Completion:: 2028-10-31

Conditions

Degenerative Osteoarthritis

Interventions

BIOLOGICAL

No Results Yet

NCT05269381 | RECRUITING | PHASE1/PHASE2

138 participants

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-03-31
Completion:: 2028-03-31

Conditions

Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IIIA Breast Cancer AJCC v8
Anatomic Stage IIIB Breast Cancer AJCC v8
Anatomic Stage IIIC Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Clinical Stage III Cutaneous Melanoma AJCC v8
Clinical Stage III Gastric Cancer AJCC v8
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage III Merkel Cell Carcinoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Clinical Stage IV Gastric Cancer AJCC v8
Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IV Merkel Cell Carcinoma AJCC v8
Clinical Stage IVA Gastric Cancer AJCC v8
Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IVB Gastric Cancer AJCC v8
Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
Locally Advanced Cervical Carcinoma
Locally Advanced Endometrial Carcinoma
Locally Advanced Gastric Adenocarcinoma
Locally Advanced Gastroesophageal Junction Adenocarcinoma
Locally Advanced Head and Neck Squamous Cell Carcinoma
Locally Advanced Hepatocellular Carcinoma
Locally Advanced Lung Non-Small Cell Carcinoma
Locally Advanced Malignant Solid Neoplasm
Locally Advanced Melanoma
Locally Advanced Merkel Cell Carcinoma
Locally Advanced Renal Cell Carcinoma
Locally Advanced Skin Squamous Cell Carcinoma
Locally Advanced Triple-Negative Breast Carcinoma
Locally Advanced Unresectable Breast Carcinoma
Locally Advanced Unresectable Cervical Carcinoma
Locally Advanced Unresectable Gastric Adenocarcinoma
Locally Advanced Unresectable Gastroesophageal Junction Adenocarcinoma
Locally Advanced Unresectable Renal Cell Carcinoma
Locally Advanced Urothelial Carcinoma
Metastatic Cervical Carcinoma
Metastatic Endometrial Carcinoma
Metastatic Gastric Adenocarcinoma
Metastatic Gastroesophageal Junction Adenocarcinoma
Metastatic Head and Neck Squamous Cell Carcinoma
Metastatic Hepatocellular Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Solid Neoplasm
Metastatic Melanoma
Metastatic Merkel Cell Carcinoma
Metastatic Renal Cell Carcinoma
Metastatic Skin Squamous Cell Carcinoma
Metastatic Triple-Negative Breast Carcinoma
Metastatic Urothelial Carcinoma
Skin Squamous Cell Carcinoma
Stage III Cervical Cancer AJCC v8
Stage III Hepatocellular Carcinoma AJCC v8
Stage III Lung Cancer AJCC v8
Stage III Renal Cell Cancer AJCC v8
Stage IIIA Cervical Cancer AJCC v8
Stage IIIA Hepatocellular Carcinoma AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIA Uterine Corpus Cancer AJCC v8
Stage IIIB Cervical Cancer AJCC v8
Stage IIIB Hepatocellular Carcinoma AJCC v8
Stage IIIB Lung Cancer AJCC v8
Stage IIIB Uterine Corpus Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Stage IIIC Uterine Corpus Cancer AJCC v8
Stage IIIC1 Uterine Corpus Cancer AJCC v8
Stage IIIC2 Uterine Corpus Cancer AJCC v8
Stage IV Cervical Cancer AJCC v8
Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Stage IV Hepatocellular Carcinoma AJCC v8
Stage IV Lung Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8
Stage IVA Cervical Cancer AJCC v8
Stage IVA Hepatocellular Carcinoma AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVA Uterine Corpus Cancer AJCC v8
Stage IVB Cervical Cancer AJCC v8
Stage IVB Hepatocellular Carcinoma AJCC v8
Stage IVB Lung Cancer AJCC v8
Stage IVB Uterine Corpus Cancer AJCC v8
Triple-Negative Breast Carcinoma
Unresectable Cervical Carcinoma
Unresectable Endometrial Carcinoma
Unresectable Gastric Adenocarcinoma
Unresectable Gastroesophageal Junction Adenocarcinoma
Unresectable Head and Neck Squamous Cell Carcinoma
Unresectable Hepatocellular Carcinoma
Unresectable Lung Non-Small Cell Carcinoma
Unresectable Malignant Solid Neoplasm
Unresectable Melanoma
Unresectable Merkel Cell Carcinoma
Unresectable Renal Cell Carcinoma
Unresectable Skin Squamous Cell Carcinoma
Unresectable Triple-Negative Breast Carcinoma
Unresectable Urothelial Carcinoma
Breast Adenocarcinoma
Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Invasive Breast Lobular Carcinoma

Interventions

DRUG
BIOLOGICAL
PROCEDURE

No Results Yet

NCT05254899 | COMPLETED | PHASE2

54 participants

A Study of Tislelizumab, Chemotherapy, and Radiation Therapy for Early-Stage High-Risk ENKTCL (CLCG-2102)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-11-10
Completion:: 2025-08-30

Conditions

Extranodal NK-T-Cell Lymphoma
Early-stage
High-Risk Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT05254327 | RECRUITING | PHASE2

118 participants

Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-08-15
Completion:: 2027-05-31

Conditions

Rectal Cancer

Interventions

DRUG

No Results Yet

NCT05235360 | COMPLETED | NA

184 participants

Factorial Trial Testing Guided Thinking Tasks to Optimize a Physical Activity Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-02-14
Completion:: 2025-04-30

Conditions

Physical Inactivity

Interventions

BEHAVIORAL

No Results Yet

NCT05232383 | COMPLETED | NA

96 participants

Benefits and Risks of Artificial Light Exposure: Characterisation of Effects on Alertness, Sleep, Cognitive Performance, Mood and Biological Rhythms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-12-02
Completion:: 2026-07-31

Conditions

Human Sleep and Chronobiology

Interventions

DEVICE

No Results Yet

NCT05219422 | ACTIVE_NOT_RECRUITING | NA

42 participants

Testing ALERT With GTO in Middle Schools

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-08-30
Completion:: 2026-07-01

Conditions

Substance Abuse

Interventions

BEHAVIORAL

No Results Yet

NCT05206994 | COMPLETED | NA

953 participants

Evaluation of the Close to Home Program in California

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-10-04
Completion:: 2025-11-13

Conditions

Sexual Violence
Sexual Assault
Adolescent Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT05206435 | COMPLETED | PHASE4

183 participants

Methadone-Maintained Smokers Switching to E-Cigarettes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-03-31
Completion:: 2025-06-30

Conditions

Nicotine Dependence
Electronic Cigarette Use

Interventions

DRUG

Results Available

NCT05197192 | RECRUITING | PHASE3

202 participants

A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-04-19
Completion:: 2028-05-31

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG

No Results Yet

NCT05180825 | RECRUITING | PHASE2

134 participants

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-05-05
Completion:: 2031-11-01

Conditions

Grade 1 Glioma
Mixed Glio-neuronal Tumors
Pleomorphic Xanthoastrocytoma

Interventions

DRUG

No Results Yet

NCT05160688 | COMPLETED | NA

146 participants

Changes in Cognition and Psychiatric Disorder Symptoms During Cannabis Abstinence Using a Novel Discordant Twin Design

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2023-05-05
Completion:: 2026-03-23

Conditions

Cannabis

Interventions

BEHAVIORAL

No Results Yet

NCT05157659 | ACTIVE_NOT_RECRUITING | NA

10 participants

[18F]F-AraG PET Imaging to Visualize Tumor Infiltrating T-cell Activation in Non-small Cell Lung Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-12-01
Completion:: 2024-01-01

Conditions

Non-Small Cell Lung Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05151471 | TERMINATED | PHASE3

202 participants

Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-01-11
Completion:: 2023-09-29

Conditions

ALS

Interventions

DRUG

Results Available

NCT05142683 | RECRUITING | NA

300 participants

Effectiveness of an Integrated Care Pathway for Depression: Cluster Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-02-01
Completion:: 2027-09-30

Conditions

Major Depressive Disorder

Interventions

OTHER

No Results Yet

NCT05138588 | RECRUITING | NA

40 participants

Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) in Cognitive Fluctuations of Dementia With Lewy Bodies (DLB): Proof of Concept

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-02-02
Completion:: 2028-02-29

Conditions

Dementia With Lewy Bodies Diagnosis
Significant Cognitive Fluctuations in DLB

Interventions

DEVICE

No Results Yet

NCT05136859 | RECRUITING | NA

100 participants

Inflammatory Marker and Pre-existing Venous Fibrosis to Predict AVF Mal-maturation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-12-11
Completion:: 2026-12-01

Conditions

Arteriovenous Fistula

Interventions

PROCEDURE

No Results Yet

NCT05127226 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

71 participants

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-12-22
Completion:: 2029-03-31

Conditions

Angelman Syndrome

Interventions

DRUG

No Results Yet

NCT05123274 | COMPLETED | NA

94 participants

Mobilizing Social Network Resources for HIV Care Support

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-01-15
Completion:: 2024-10-31

Conditions

HIV Infections

Interventions

BEHAVIORAL

Results Available

NCT05117983 | ACTIVE_NOT_RECRUITING | NA

90 participants

Non-invasive Brain Stimulation Normalizes Dopaminergic Transmission in the Frontostriatal Circuit to Alleviate Depression With Metabolic Disorders.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-08-26
Completion:: 2027-07-31

Conditions

Depression

Interventions

DEVICE

No Results Yet

NCT05111756 | COMPLETED

49 participants

Braining - Physical Exercise in Psychiatry - Evaluation of Feasibility, Implementation and Health Among Staff

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-12-02
Completion:: 2025-05-30

Conditions

Physical Inactivity
Occupational Stress

No Results Yet

NCT05110742 | RECRUITING | PHASE1/PHASE2

64 participants

Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2024-04-22
Completion:: 2030-12-31

Conditions

Hematological Malignancy

Interventions

DRUG

No Results Yet

NCT05101148 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2021-07-21
Completion:: 2022-04-06

Conditions

Neurofibromatosis Type 1

Interventions

DRUG

No Results Yet

NCT05081596 | RECRUITING | NA

100 participants

A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-06-03
Completion:: 2027-07-31

Conditions

Depression
Pain
Cognitive Impairment

Interventions

BEHAVIORAL

No Results Yet

NCT05075317 | COMPLETED | NA

45 participants

Time Restricted Eating and Cardiac Rehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2022-07-11
Completion:: 2025-05-31

Conditions

Coronary Artery Disease

Interventions

BEHAVIORAL

No Results Yet

NCT05074030 | COMPLETED | NA

60 participants

EMA/EMI for Psychiatrically Hospitalized Emerging Adults Who Drink to Cope

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-20
Start Date:: 2023-02-06
Completion:: 2025-06-30

Conditions

Alcohol Use Disorder

Interventions

BEHAVIORAL

Results Available