Clinical Trials

NCT05285007 | RECRUITING | NA

60 participants

Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-03-02

Completion:

2027-05-31

Conditions

• Patellofemoral Pain

Interventions

• OTHER

No Results Yet

NCT05276011 | NOT_YET_RECRUITING | PHASE2

255 participants

A Study to Determine the Safety and Efficacy of TG-C in Subjects With Symptomatic Early Hip Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2027-10-31

Completion:

2028-10-31

Conditions

• Degenerative Osteoarthritis

Interventions

• BIOLOGICAL

No Results Yet

NCT05269381 | RECRUITING | PHASE1/PHASE2

138 participants

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-03-31

Completion:

2028-03-31

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Anatomic Stage IIIB Breast Cancer AJCC v8
• Anatomic Stage IIIC Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Clinical Stage III Cutaneous Melanoma AJCC v8
• Clinical Stage III Gastric Cancer AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage III Merkel Cell Carcinoma AJCC v8
• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Clinical Stage IV Gastric Cancer AJCC v8
• Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IV Merkel Cell Carcinoma AJCC v8
• Clinical Stage IVA Gastric Cancer AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVB Gastric Cancer AJCC v8
• Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Locally Advanced Cervical Carcinoma
• Locally Advanced Endometrial Carcinoma
• Locally Advanced Gastric Adenocarcinoma
• Locally Advanced Gastroesophageal Junction Adenocarcinoma
• Locally Advanced Head and Neck Squamous Cell Carcinoma
• Locally Advanced Hepatocellular Carcinoma
• Locally Advanced Lung Non-Small Cell Carcinoma
• Locally Advanced Malignant Solid Neoplasm
• Locally Advanced Melanoma
• Locally Advanced Merkel Cell Carcinoma
• Locally Advanced Renal Cell Carcinoma
• Locally Advanced Skin Squamous Cell Carcinoma
• Locally Advanced Triple-Negative Breast Carcinoma
• Locally Advanced Unresectable Breast Carcinoma
• Locally Advanced Unresectable Cervical Carcinoma
• Locally Advanced Unresectable Gastric Adenocarcinoma
• Locally Advanced Unresectable Gastroesophageal Junction Adenocarcinoma
• Locally Advanced Unresectable Renal Cell Carcinoma
• Locally Advanced Urothelial Carcinoma
• Metastatic Cervical Carcinoma
• Metastatic Endometrial Carcinoma
• Metastatic Gastric Adenocarcinoma
• Metastatic Gastroesophageal Junction Adenocarcinoma
• Metastatic Head and Neck Squamous Cell Carcinoma
• Metastatic Hepatocellular Carcinoma
• Metastatic Lung Non-Small Cell Carcinoma
• Metastatic Malignant Solid Neoplasm
• Metastatic Melanoma
• Metastatic Merkel Cell Carcinoma
• Metastatic Renal Cell Carcinoma
• Metastatic Skin Squamous Cell Carcinoma
• Metastatic Triple-Negative Breast Carcinoma
• Metastatic Urothelial Carcinoma
• Skin Squamous Cell Carcinoma
• Stage III Cervical Cancer AJCC v8
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage III Lung Cancer AJCC v8
• Stage III Renal Cell Cancer AJCC v8
• Stage IIIA Cervical Cancer AJCC v8
• Stage IIIA Hepatocellular Carcinoma AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIA Uterine Corpus Cancer AJCC v8
• Stage IIIB Cervical Cancer AJCC v8
• Stage IIIB Hepatocellular Carcinoma AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIB Uterine Corpus Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IIIC Uterine Corpus Cancer AJCC v8
• Stage IIIC1 Uterine Corpus Cancer AJCC v8
• Stage IIIC2 Uterine Corpus Cancer AJCC v8
• Stage IV Cervical Cancer AJCC v8
• Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8
• Stage IVA Cervical Cancer AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVA Uterine Corpus Cancer AJCC v8
• Stage IVB Cervical Cancer AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8
• Stage IVB Lung Cancer AJCC v8
• Stage IVB Uterine Corpus Cancer AJCC v8
• Triple-Negative Breast Carcinoma
• Unresectable Cervical Carcinoma
• Unresectable Endometrial Carcinoma
• Unresectable Gastric Adenocarcinoma
• Unresectable Gastroesophageal Junction Adenocarcinoma
• Unresectable Head and Neck Squamous Cell Carcinoma
• Unresectable Hepatocellular Carcinoma
• Unresectable Lung Non-Small Cell Carcinoma
• Unresectable Malignant Solid Neoplasm
• Unresectable Melanoma
• Unresectable Merkel Cell Carcinoma
• Unresectable Renal Cell Carcinoma
• Unresectable Skin Squamous Cell Carcinoma
• Unresectable Triple-Negative Breast Carcinoma
• Unresectable Urothelial Carcinoma
• Breast Adenocarcinoma
• Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
• Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
• Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
• Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
• Invasive Breast Lobular Carcinoma

Interventions

• DRUG
• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT05254899 | COMPLETED | PHASE2

54 participants

A Study of Tislelizumab, Chemotherapy, and Radiation Therapy for Early-Stage High-Risk ENKTCL (CLCG-2102)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-11-10

Completion:

2025-08-30

Conditions

• Extranodal NK-T-Cell Lymphoma
• Early-stage
• High-Risk Cancer

Interventions

• DRUG
• RADIATION

No Results Yet

NCT05254327 | RECRUITING | PHASE2

118 participants

Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-08-15

Completion:

2027-05-31

Conditions

• Rectal Cancer

Interventions

• DRUG

No Results Yet

NCT05235360 | COMPLETED | NA

184 participants

Factorial Trial Testing Guided Thinking Tasks to Optimize a Physical Activity Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-02-14

Completion:

2025-04-30

Conditions

• Physical Inactivity

Interventions

• BEHAVIORAL

No Results Yet

NCT05232383 | COMPLETED | NA

96 participants

Benefits and Risks of Artificial Light Exposure: Characterisation of Effects on Alertness, Sleep, Cognitive Performance, Mood and Biological Rhythms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-02

Completion:

2026-07-31

Conditions

• Human Sleep and Chronobiology

Interventions

• DEVICE

No Results Yet

NCT05219422 | ACTIVE_NOT_RECRUITING | NA

42 participants

Testing ALERT With GTO in Middle Schools

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-08-30

Completion:

2026-07-01

Conditions

• Substance Abuse

Interventions

• BEHAVIORAL

No Results Yet

NCT05206994 | COMPLETED | NA

953 participants

Evaluation of the Close to Home Program in California

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-10-04

Completion:

2025-11-13

Conditions

• Sexual Violence
• Sexual Assault
• Adolescent Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT05206435 | COMPLETED | PHASE4

183 participants

Methadone-Maintained Smokers Switching to E-Cigarettes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-03-31

Completion:

2025-06-30

Conditions

• Nicotine Dependence
• Electronic Cigarette Use

Interventions

• DRUG

Results Available

NCT05197192 | RECRUITING | PHASE3

202 participants

A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-04-19

Completion:

2028-05-31

Conditions

• Chronic Lymphocytic Leukemia

Interventions

• DRUG

No Results Yet

NCT05180825 | RECRUITING | PHASE2

134 participants

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-05-05

Completion:

2031-11-01

Conditions

• Grade 1 Glioma
• Mixed Glio-neuronal Tumors
• Pleomorphic Xanthoastrocytoma

Interventions

• DRUG

No Results Yet

NCT05160688 | COMPLETED | NA

146 participants

Changes in Cognition and Psychiatric Disorder Symptoms During Cannabis Abstinence Using a Novel Discordant Twin Design

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2023-05-05

Completion:

2026-03-23

Conditions

• Cannabis

Interventions

• BEHAVIORAL

No Results Yet

NCT05157659 | ACTIVE_NOT_RECRUITING | NA

10 participants

[18F]F-AraG PET Imaging to Visualize Tumor Infiltrating T-cell Activation in Non-small Cell Lung Cancer.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-01

Completion:

2024-01-01

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05151471 | TERMINATED | PHASE3

202 participants

Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-01-11

Completion:

2023-09-29

Conditions

• ALS

Interventions

• DRUG

Results Available

NCT05142683 | RECRUITING | NA

300 participants

Effectiveness of an Integrated Care Pathway for Depression: Cluster Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-02-01

Completion:

2027-09-30

Conditions

• Major Depressive Disorder

Interventions

• OTHER

No Results Yet

NCT05138588 | RECRUITING | NA

40 participants

Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) in Cognitive Fluctuations of Dementia With Lewy Bodies (DLB): Proof of Concept

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-02-02

Completion:

2028-02-29

Conditions

• Dementia With Lewy Bodies Diagnosis
• Significant Cognitive Fluctuations in DLB

Interventions

• DEVICE

No Results Yet

NCT05136859 | RECRUITING | NA

100 participants

Inflammatory Marker and Pre-existing Venous Fibrosis to Predict AVF Mal-maturation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-11

Completion:

2026-12-01

Conditions

• Arteriovenous Fistula

Interventions

• PROCEDURE

No Results Yet

NCT05127226 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

71 participants

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-22

Completion:

2029-03-31

Conditions

• Angelman Syndrome

Interventions

• DRUG

No Results Yet

NCT05123274 | COMPLETED | NA

94 participants

Mobilizing Social Network Resources for HIV Care Support

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-01-15

Completion:

2024-10-31

Conditions

• HIV Infections

Interventions

• BEHAVIORAL

Results Available

NCT05117983 | ACTIVE_NOT_RECRUITING | NA

90 participants

Non-invasive Brain Stimulation Normalizes Dopaminergic Transmission in the Frontostriatal Circuit to Alleviate Depression With Metabolic Disorders.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-08-26

Completion:

2027-07-31

Conditions

• Depression

Interventions

• DEVICE

No Results Yet

NCT05111756 | COMPLETED

49 participants

Braining - Physical Exercise in Psychiatry - Evaluation of Feasibility, Implementation and Health Among Staff

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-02

Completion:

2025-05-30

Conditions

• Physical Inactivity
• Occupational Stress

No Results Yet

NCT05110742 | RECRUITING | PHASE1/PHASE2

64 participants

Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2024-04-22

Completion:

2030-12-31

Conditions

• Hematological Malignancy

Interventions

• DRUG

No Results Yet

NCT05101148 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-07-21

Completion:

2022-04-06

Conditions

• Neurofibromatosis Type 1

Interventions

• DRUG

No Results Yet

NCT05081596 | RECRUITING | NA

100 participants

A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-06-03

Completion:

2027-07-31

Conditions

• Depression
• Pain
• Cognitive Impairment

Interventions

• BEHAVIORAL

No Results Yet

NCT05075317 | COMPLETED | NA

45 participants

Time Restricted Eating and Cardiac Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-07-11

Completion:

2025-05-31

Conditions

• Coronary Artery Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT05074030 | COMPLETED | NA

60 participants

EMA/EMI for Psychiatrically Hospitalized Emerging Adults Who Drink to Cope

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2023-02-06

Completion:

2025-06-30

Conditions

• Alcohol Use Disorder

Interventions

• BEHAVIORAL

Results Available

NCT05064150 | ACTIVE_NOT_RECRUITING

2539 participants

Neuroendocrine Tumors - Patient Reported Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2022-05-10

Completion:

2026-10-31

Conditions

• Neuroendocrine Tumors
• Gastroenteropancreatic Neuroendocrine Tumor
• Lung Neuroendocrine Neoplasm
• Neuroendocrine Carcinoma

No Results Yet

NCT05040165 | COMPLETED | NA

64 participants

Investigation on Failure Time Analysis of a New TPE Material in the Iceform Liner

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-12-08

Completion:

2020-08-30

Conditions

• Prosthesis Failure

Interventions

• DEVICE

Results Available

NCT05039866 | ACTIVE_NOT_RECRUITING

32 participants

Long-Term Follow-up of Subjects Who Were Treated With ST-920

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2021-08-16

Completion:

2029-03-31

Conditions

• Fabry Disease
• Fabry Disease, Cardiac Variant

Interventions

• BIOLOGICAL

No Results Yet

NCT05031078 | COMPLETED | PHASE4

17 participants

Assessing Durable Antibody Response to HPV Vaccination

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-21

Completion:

2024-10-23

Conditions

• HPV

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT05014971 | ACTIVE_NOT_RECRUITING | NA

106 participants

Telehealth in Lewy Body Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-02-28

Completion:

2026-10-31

Conditions

• Lewy Body Dementia With Behavioral Disturbance
• Lewy Body Parkinson Disease
• Lewy Body Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT05007990 | RECRUITING

2800 participants

Caregiving Networks Across Disease Context and the Life Course

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2022-09-08

Completion:

2030-12-31

Conditions

• Inherited Metabolic Disorders
• Undiagnosed Diseases
• Batten's Disease
• Tay Sachs
• Diabetes

No Results Yet

NCT04988295 | ACTIVE_NOT_RECRUITING | PHASE3

776 participants

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-11-17

Completion:

2023-07-10

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT04982757 | ENROLLING_BY_INVITATION | NA

500 participants

Accelerated TMS for Depression and OCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-07

Completion:

2027-05-31

Conditions

• Depression
• OCD

Interventions

• DEVICE

No Results Yet

NCT04981912 | COMPLETED | PHASE1

4 participants

Rituximab + High-Dose Methylprednisolone Debulking Prior to Venetoclax for CLL & SLL Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-09-02

Completion:

2025-07-31

Conditions

• Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Interventions

• DRUG

Results Available

NCT04972006 | COMPLETED | NA

16 participants

Brief, Remote Treatment of Youth Injection Phobia and Measurement of Novel, Disorder-congruent Cognitive Bias Tasks

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-07-15

Completion:

2022-06-03

Conditions

• Anxiety Disorder of Childhood

Interventions

• BEHAVIORAL

No Results Yet

NCT04945642 | RECRUITING | NA

52 participants

High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-08-20

Completion:

2027-07-01

Conditions

• Prostate Adenocarcinoma
• Stage IIB Prostate Cancer American Joint Committee on Cancer (AJCC) v8
• Stage IIC Prostate Cancer AJCC v8
• Stage III Prostate Cancer AJCC v8
• Stage IIIA Prostate Cancer AJCC v8
• Stage IIIB Prostate Cancer AJCC v8
• Stage IIIC Prostate Cancer AJCC v8
• Stage IVA Prostate Cancer AJCC v8

Interventions

• RADIATION

No Results Yet

NCT04936308 | COMPLETED | PHASE3

453 participants

Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-09-28

Completion:

2024-10-28

Conditions

• Arthritis, Psoriatic

Interventions

• DRUG

Results Available

NCT04933903 | RECRUITING | PHASE2

25 participants

BrUOG 397: NEO Rad (LOW): Neoadjuvant Low Dose Stereotactic Body Radiotherapy, Ipilimumab and Nivolumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-10-05

Completion:

2026-10-31

Conditions

• Non Small Cell Lung Cancer

Interventions

• DRUG
• RADIATION

No Results Yet