Clinical Trials

NCT04573530 | COMPLETED | NA

53 participants

We Walk Plus Study for Older Adults With Intellectual Disabilities

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-06-15

Completion:

2026-01-15

Conditions

• Intellectual Disability

Interventions

• BEHAVIORAL

No Results Yet

NCT04572451 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-11-29

Completion:

2026-10-07

Conditions

• Melanoma
• Unresectable Solid Tumors
• Neoplasms
• Neoplasms by Histologic Type
• Neoplasms by Site
• Antineoplastic Agents, Immunological
• Antineoplastic Agents
• Immune Checkpoint Inhibitors
• Molecular Mechanisms of Pharmacological Action
• Nivolumab

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04569773 | ACTIVE_NOT_RECRUITING

43 participants

Choosing Ovarian Preservation or Removal Before Surgery for Endometrial Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2020-09-23

Completion:

2027-09-23

Conditions

• Endometrial Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04569227 | WITHDRAWN | PHASE2

0 participants

Prevention of COVID-19 Infection to Severe Pneumonia or ARDS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-04-30

Completion:

2021-09-30

Conditions

• Covid19 Pneumonia

Interventions

• DRUG

No Results Yet

NCT04557449 | ACTIVE_NOT_RECRUITING | PHASE2

362 participants

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-09-23

Completion:

2026-09-23

Conditions

• Liposarcoma
• Prostate Cancer
• Breast Neoplasms
• Adenocarcinoma of Lung

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT04545502 | RECRUITING

2000 participants

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2021-02-17

Completion:

2028-08-31

Conditions

• Aneurysm
• Dissection
• Aortic Root Aneurysm
• Aortic Root Dissection
• Carotid Artery Injuries
• Aortic Arch
• Bypass Extremity Graft
• Occlusive Vascular Disease
• Aortic Diseases

Interventions

• DEVICE

No Results Yet

NCT04515238 | ACTIVE_NOT_RECRUITING | PHASE2

42 participants

Sequential Regimen of Bendamustine Followed by Obinutuzumab (GA101), Zanubrutinib (BGB-3111) and Venetoclax (ABT-199) in Patients With Relapsed/Refractory CLL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-10-01

Completion:

2027-02-28

Conditions

• Chronic Lymphoid Leukemia

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04497844 | ACTIVE_NOT_RECRUITING | PHASE3

696 participants

A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-09-23

Completion:

2025-01-07

Conditions

• Metastatic Castration-sensitive Prostate Cancer

Interventions

• COMBINATION_PRODUCT
• DRUG

Results Available

NCT04477759 | COMPLETED | PHASE1

18 participants

Dose-Escalated Hypofractionated Adaptive Radiotherapy for Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-01-26

Completion:

2024-04-08

Conditions

• Head and Neck Neoplasm

Interventions

• RADIATION
• DRUG

Results Available

NCT04474847 | RECRUITING | PHASE3

78 participants

Abatacept for the Treatment of Giant Cell Arteritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-03-29

Completion:

2029-12-31

Conditions

• Giant Cell Arteritis

Interventions

• DRUG

No Results Yet

NCT04473781 | TERMINATED | PHASE1

2 participants

Interstitial Brachytherapy for the Treatment of Unresectable/Unablatable Kidney Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-07-16

Completion:

2025-09-04

Conditions

• Stage I Renal Cell Cancer
• Stage II Renal Cell Cancer

Interventions

• PROCEDURE

No Results Yet

NCT04457622 | COMPLETED | NA

264 participants

Language and Brain Rhythms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-02-18

Completion:

2026-03-16

Conditions

• Healthy Volunteers

Interventions

• OTHER

No Results Yet

NCT04457232 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

Prospective Exploratory Study of FAPi PET/CT in Prostate Cancer With Histopathology Validation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-09-09

Completion:

2023-05-30

Conditions

• Metastatic Malignant Neoplasm in the Prostate Gland
• Prostate Carcinoma
• Recurrent Prostate Carcinoma

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04417062 | ACTIVE_NOT_RECRUITING | PHASE2

49 participants

Olaparib With Ceralasertib in Recurrent Osteosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-11-24

Completion:

2025-06-01

Conditions

• Osteosarcoma
• Osteosarcoma Recurrent

Interventions

• DRUG

Results Available

NCT04410302 | RECRUITING

500 participants

Patient-Derived Xenografts to Reduce Cancer Health Disparities

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2019-11-12

Completion:

2026-12-31

Conditions

• Bladder Carcinoma
• Gastric Carcinoma
• Liver and Intrahepatic Bile Duct Carcinoma
• Lung Carcinoma
• Malignant Neoplasm

Interventions

• PROCEDURE

No Results Yet

NCT04408950 | COMPLETED

19 participants

Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2020-11-12

Completion:

2025-01-27

Conditions

• Immunodeficiency

No Results Yet

NCT04404088 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Acalabrutinib, Lenalidomide, and Rituximab for the Treatment of CD20 Positive Stage III-IV, Grade 1-3a Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-07-16

Completion:

2028-03-01

Conditions

• Ann Arbor Stage III Grade 1 Follicular Lymphoma
• Ann Arbor Stage III Grade 2 Follicular Lymphoma
• Ann Arbor Stage III Grade 3 Follicular Lymphoma
• Ann Arbor Stage IV Grade 1 Follicular Lymphoma
• Ann Arbor Stage IV Grade 2 Follicular Lymphoma
• Ann Arbor Stage IV Grade 3 Follicular Lymphoma
• Grade 3a Follicular Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04388605 | ACTIVE_NOT_RECRUITING

7965 participants

Assessing the Safety of Pregnancy In the CoRonavirus (COVID-19) pandEmic

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2020-04-21

Completion:

2026-12-31

Conditions

• Corona Virus Infection
• COVID
• Pregnancy Related
• Early Pregnancy

No Results Yet

NCT04355572 | RECRUITING | NA

60 participants

Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2026-09-30

Completion:

2028-08-31

Conditions

• Polycystic Ovarian Syndrome in Adolescent Females
• Vitamin D Deficiency

Interventions

• DRUG

No Results Yet

NCT04335994 | RECRUITING | NA

200 participants

ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-09-23

Completion:

2026-12-31

Conditions

• Obstructive Sleep Apnea
• Alzheimer Disease
• Vascular Dementia
• Mild Cognitive Impairment
• Parkinsons Disease With Dementia
• Dementia With Lewy Bodies
• Mixed Dementia

Interventions

• DEVICE

No Results Yet

NCT04318808 | COMPLETED | NA

40 participants

Effect of Laser Acupuncture on Constipation in Patients With Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-03-30

Completion:

2022-02-28

Conditions

• Constipation
• Advanced Cancer

Interventions

• PROCEDURE

No Results Yet

NCT04311437 | COMPLETED | NA

152 participants

Effect of Self-acupressure on Middle Ear Barotrauma Associated With Hyperbaric Oxygen Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-03-01

Completion:

2023-02-28

Conditions

• Hyperbaric Oxygen Therapy
• Middle Ear Barotrauma

Interventions

• PROCEDURE

No Results Yet

NCT04292574 | RECRUITING

800 participants

UK SMA Patient Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2008-07-13

Completion:

2040-01-01

Conditions

• Spinal Muscular Atrophy
• SMA

Interventions

• OTHER

No Results Yet

NCT04271956 | RECRUITING | PHASE2

83 participants

Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment With or Without Sonrotoclax for Patients With Richter Transformation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-02-19

Completion:

2027-08-31

Conditions

• Richter Transformation

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04222023 | COMPLETED | PHASE4

359 participants

Intravenous Immunoglobulins for Prevention of BKV Infection in Kidney Transplant Recipients According to BKV Genotype-specific Neutralizing Antibody Titers at the Day of Transplantation.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-08-21

Completion:

2026-08-01

Conditions

• Kidney Transplantation

Interventions

• DRUG

No Results Yet

NCT04220021 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-01-10

Completion:

2024-08-26

Conditions

• C9orf72 Amyotrophic Lateral Sclerosis (ALS)
• Frontotemporal Dementia

Interventions

• DRUG

Results Available

NCT04205968 | RECRUITING | PHASE2

94 participants

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-06-01

Completion:

2027-02-01

Conditions

• Metastatic Small Intestinal Adenocarcinoma
• Stage III Small Intestinal Adenocarcinoma AJCC v8
• Stage IIIA Small Intestinal Adenocarcinoma AJCC v8
• Stage IIIB Small Intestinal Adenocarcinoma AJCC v8
• Stage IV Small Intestinal Adenocarcinoma AJCC v8

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04199780 | COMPLETED | NA

106 participants

Effects of tDCS Combined With CBI on Postsurgical Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-01-11

Completion:

2026-01-01

Conditions

• Total Knee Arthroplasty (Postoperative Pain)
• Total Hip Arthroplasty (Postoperative Pain)

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04159597 | AVAILABLE

Expanded Access to Upadacitinib

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-20

Conditions

• Crohn Disease
• Ulcerative Colitis
• Idiopathic Arthritis (Including sJIA, pJIA, or JPsA)
• Atopic Dermatitis
• Rheumatoid Arthritis
• Psoriatic Arthritis
• Axial Spondyloarthritis
• Non-radiographic Axial
• Spondyloarthritis
• Giant Cell Arteritis
• Systemic Lupus Erythematosus
• Alopecia Areata
• Non Segmental Vitiligo
• Hidradenitis Suppurativa

Interventions

• DRUG

No Results Yet

NCT04159298 | COMPLETED | NA

58 participants

Cervicogenic Concussion Rehabilitation With TopSpin360

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2022-05-06

Completion:

2023-12-12

Conditions

• Concussion, Mild

Interventions

• DEVICE

No Results Yet

NCT04151667 | COMPLETED | PHASE2

33 participants

Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-11-22

Completion:

2023-11-08

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT04150198 | RECRUITING | NA

45 participants

MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-08

Completion:

2028-12-31

Conditions

• Alzheimer Disease, Early Onset
• Posterior Cortical Atrophy

Interventions

• DEVICE

No Results Yet

NCT04124965 | COMPLETED | PHASE3

71 participants

A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-10-29

Completion:

2021-09-01

Conditions

• Generalized Myasthenia Gravis

Interventions

• DRUG

Results Available

NCT04112641 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

NIAGEN and Persistent Chemotherapy-Induced Peripheral Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-02-19

Completion:

2027-06-28

Conditions

• Chemotherapy-induced Peripheral Neuropathy

Interventions

• DRUG

No Results Yet

NCT04076462 | COMPLETED | PHASE3

72 participants

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-08-19

Completion:

2023-05-02

Conditions

• Acromegaly

Interventions

• DRUG

Results Available

NCT04064593 | COMPLETED | NA

2007 participants

Sleep Disordered Breathing (SDB) Prevalence and Cardiovascular Outcomes of Myocardial Infarction (MI) Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-04-09

Completion:

2023-12-03

Conditions

• Acute Myocardial Infarction
• Sleep Apnea

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04057833 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-11-20

Completion:

2026-10-31

Conditions

• Rotator Cuff Tears
• Muscle Atrophy or Weakness
• Tendon Rupture - Shoulder
• Safety Issues

Interventions

• DRUG

No Results Yet

NCT04034550 | ACTIVE_NOT_RECRUITING | NA

200 participants

Cohort of Hospitalized Patients Suspected of Leptospirosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-01-06

Completion:

2026-09-06

Conditions

• Leptospirosis

Interventions

• OTHER

No Results Yet

NCT04021355 | COMPLETED | NA

61 participants

Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-11-14

Completion:

2025-06-14

Conditions

• Obesity
• Hypertension
• Circadian Dysregulation
• Salt; Excess

Interventions

• OTHER

Results Available

NCT04018625 | COMPLETED | NA

63 participants

The Stony Brook University Calm-Mom Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-04-01

Completion:

2023-06-01

Conditions

• Pregnancy Related
• Stress, Psychological
• Anxiety
• Perinatal Depression

Interventions

• BEHAVIORAL

Results Available