Clinical Trials Updated in 2026

NCT07187973 | RECRUITING | PHASE1

24 participants

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-01-06
Completion:: 2027-06-30

Conditions

Sickle Cell Disease

Interventions

DRUG

No Results Yet

NCT07185373 | RECRUITING | PHASE2/PHASE3

215 participants

Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-10-01
Completion:: 2028-09-30

Conditions

Primary Central Nervous System Lymphoma

Interventions

DRUG

No Results Yet

NCT07181109 | RECRUITING | PHASE3

11000 participants

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-09-22
Completion:: 2030-09-30

Conditions

High Risk Cardiovascular Disease
Hypertension
High Cardiovascular Risk

Interventions

DRUG

No Results Yet

NCT07179003 | NOT_YET_RECRUITING | PHASE2

50 participants

A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2027-07-31
Completion:: 2032-06-30

Conditions

Breast Abscess

Interventions

PROCEDURE
DRUG
DEVICE

No Results Yet

NCT07175922 | RECRUITING

200 participants

Research Into the Expression of the csgA-gene and How it Changes in Patients With Parkinson's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-09-25
Completion:: 2026-11-30

Conditions

Parkinsons Disease (PD)

No Results Yet

NCT07175389 | NOT_YET_RECRUITING | PHASE1/PHASE2

10 participants

JDB153 Combined With Serplulimab for Pancreatic Cancer After Standard Treatment Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-09-01
Completion:: 2028-09-01

Conditions

Refractory Pancreatic Ductal Adenocarcinoma
Refractory Pancreatic Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT07162909 | RECRUITING

500 participants

The Time Before the Crime - Risk Patterns in Offenders Undergoing a Forensic Psychiatric Evaluation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-06-01
Completion:: 2027-06-01

Conditions

Crime

No Results Yet

NCT07154160 | NOT_YET_RECRUITING | NA

21 participants

Closed-loop TMS for the Core Clinical Features of the Methamphetamine Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-08-31
Completion:: 2026-09-30

Conditions

Methamphetamine Use Disorder
Substance Use Disorder
Cue-reactivity
Craving

Interventions

DEVICE

No Results Yet

NCT07151417 | RECRUITING | PHASE2/PHASE3

240 participants

Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-09-01
Completion:: 2027-08-31

Conditions

Knee Osteoarthritis
Musculoskeletal Disease
Surgery

Interventions

DRUG

No Results Yet

NCT07148947 | RECRUITING | PHASE2

27 participants

Pacritinib With Standard of Care Azacitidine or Decitabine as a Bridge to Allogeneic Hematopoietic Stem Cell Transplant for Patients With Accelerated and Blast Phase Myeloproliferative Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-03-02
Completion:: 2028-12-31

Conditions

Accelerated Phase Myeloproliferative Neoplasm
Blast Phase Myeloproliferative Neoplasm

Interventions

DRUG
OTHER
PROCEDURE

No Results Yet

NCT07141966 | COMPLETED

35 participants

Assessment of Physical Activity, Balance, Muscle Strength, and Cognitive Function in Patients Diagnosed With Schizophrenia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-08-19
Completion:: 2025-08-30

Conditions

Schizophrenia Disorder

No Results Yet

NCT07128303 | RECRUITING | PHASE1

476 participants

Study of GS-5319 Given Alone or in Combination in Adults With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-08-28
Completion:: 2028-05-31

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT07124559 | NOT_YET_RECRUITING | PHASE1/PHASE2

144 participants

A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-10-15
Completion:: 2028-01-31

Conditions

Tuberculosis

Interventions

DRUG

No Results Yet

NCT07119658 | COMPLETED | NA

20 participants

Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-08
Completion:: 2026-05-06

Conditions

Hypertension
Hyperglycemia
Dyslipidemia
Metabolic Syndrome
Obesity &Amp; Overweight
Diabetes
Hyperlipidemia
Emergency Medicine

Interventions

BEHAVIORAL

No Results Yet

NCT07115043 | RECRUITING | PHASE1/PHASE2

120 participants

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-29
Completion:: 2029-10-02

Conditions

Melanoma
Non-small Cell Lung Cancer
Squamous Cell Carcinoma (Skin)
Renal Cell Carcinoma
Merkel Cell Carcinoma
Triple Negative Breast Cancer
Head and Neck Squamous Cell Carcinoma
Gastric Cancer/Gastroesophageal Junction Cancer
High Grade Serous Ovarian Carcinoma

Interventions

DRUG

No Results Yet

NCT07113093 | COMPLETED | NA

75 participants

The Effects of Augmented Reality Versus Virtual Reality

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-08-01
Completion:: 2026-06-30

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT07111663 | RECRUITING

200 participants

An Observational Study of Individuals With Isolated Dystonia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-06-17
Completion:: 2026-10-31

Conditions

Isolated/Primary Dystonia That Affects More Than One Region of the Body

No Results Yet

NCT07109531 | RECRUITING | PHASE3

286 participants

ASKC202 Combined With Limertinib Versus Platinum-based Chemotherapy in Treatment of Locally Advanced or Metastatic NSCLC With MET Amplification/Overexpression After Failure of EGFR-TKI Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-08-04
Completion:: 2027-10-31

Conditions

Locally Advanced or Metastatic NSCLC

Interventions

DRUG

No Results Yet

NCT07109427 | RECRUITING | NA

40000 participants

Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-08-11
Completion:: 2031-08-31

Conditions

Prostate Cancer
Cancer of the Prostate

Interventions

OTHER

No Results Yet

NCT07101094 | RECRUITING

300 participants

Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-09-22
Completion:: 2029-01-31

Conditions

Schizophrenia

Interventions

DRUG

No Results Yet

NCT07099638 | RECRUITING | PHASE2

496 participants

Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-07-21
Completion:: 2029-06-01

Conditions

Smoking Cessation

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT07092540 | RECRUITING

105 participants

The Baby Duchenne Study: Characterizing Developmental and Clinical Outcomes in the First Three Years in Children With Duchenne Muscular Dystrophy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-06-03
Completion:: 2029-08-31

Conditions

Duchenne Muscular Dystrophy (DMD)

No Results Yet

NCT07091396 | ACTIVE_NOT_RECRUITING | NA

55 participants

Home Transcranial Direct Current Stimulation (tDCS) to Enhance Functional Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-01-16
Completion:: 2030-12-31

Conditions

Stroke
Neurodegeneration
Brain Tumor

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT07090174 | WITHDRAWN | PHASE2

0 participants

CASCADE: Testing for Safety and Immune Effects of PDS0101, an Anti-HPV Therapy, Among People Living With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-04-30
Completion:: 2026-12-31

Conditions

HPV Associated Cancers
HIV (Human Immunodeficiency Virus)
Anal Cancer
Cervical Cancer
HPV 16 Infection

Interventions

BIOLOGICAL

No Results Yet

NCT07085416 | COMPLETED | NA

20 participants

Sensor Ankle Brace for Special Operations Rehabilitation - Phase 1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-10-16
Completion:: 2026-01-15

Conditions

Gait
Balance
Biomechanical Data
Postural Control
Locomotion

Interventions

DEVICE

No Results Yet

NCT07084558 | RECRUITING | NA

350 participants

ABCSG 61 / TEODOR : Neoadjuvant TrEatment Optimization Driven by Circulating Tumor DNA and endOcrine Responsiveness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-08-13
Completion:: 2028-06-30

Conditions

Early and Locally Advanced Breast Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07084389 | RECRUITING | NA

136 participants

A Financial Social Work Intervention for Families With Complex Financial Difficulties (FinSoc)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-01
Completion:: 2026-10-30

Conditions

Financial Difficulties

Interventions

BEHAVIORAL

No Results Yet

NCT07077785 | COMPLETED | NA

80 participants

The Effects of Epidural Analgesia on Maternal-Infant Bonding and Birth-Related Trauma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-25
Completion:: 2025-08-30

Conditions

Epidural Anesthesia in Labor and Delivery

Interventions

PROCEDURE

No Results Yet

NCT07073352 | RECRUITING | NA

30 participants

ACEs, SIRT1, and Premature Vascular Aging in Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-27
Completion:: 2026-12-31

Conditions

Adverse Childhood Experiences
Endothelial Dysfunction

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07070219 | RECRUITING | PHASE1/PHASE2

118 participants

A Study of CTD402 in T-ALL/LBL Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-10-07
Completion:: 2028-09-30

Conditions

Acute Lymphocytic Leukemia Refractory
Lymphoma, Lymphoblastic

Interventions

DRUG

No Results Yet

NCT07052786 | COMPLETED | NA

49 participants

Development and Effectiveness Evaluation of a Clustered Care Guideline Within Individualized Developmental Care: RCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-01
Completion:: 2025-11-01

Conditions

Premature Infant
Clustered Care
Neonatal Intensive Care Unit
Developmental Care

Interventions

BEHAVIORAL

No Results Yet

NCT07050589 | ACTIVE_NOT_RECRUITING | NA

80 participants

Group Recreation to Enhance Function Aging

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-10-15
Completion:: 2027-02-01

Conditions

Physical Functioning
Cognitive Functioning

Interventions

BEHAVIORAL

No Results Yet

NCT07049653 | RECRUITING

500 participants

Anifrolumab Pregnancy Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-06-04
Completion:: 2030-12-10

Conditions

Systemic Lupus Erythematosus

No Results Yet

NCT07043738 | NOT_YET_RECRUITING | NA

160 participants

Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-10-01
Completion:: 2031-10-01

Conditions

Major Depressive Disorder (MDD)

Interventions

PROCEDURE

No Results Yet

NCT07038473 | RECRUITING | NA

3500 participants

Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-12-17
Completion:: 2026-12-25

Conditions

Type 1 Diabetes

Interventions

PROCEDURE

No Results Yet

NCT07033195 | ACTIVE_NOT_RECRUITING | NA

200 participants

Virtual Reality Treatment for Adults With Chronic Back Pain (VRNT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-06-01
Completion:: 2027-02-20

Conditions

Chronic Pain
Chronic Back Pain
Chronic Lower Back Pain (CLBP)

Interventions

DEVICE

No Results Yet

NCT07032766 | RECRUITING

220 participants

Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-08-10
Completion:: 2027-07-31

Conditions

Pain Management
Rib Fracture Multiple
Serratus Anterior Plane Block

No Results Yet

NCT07032727 | RECRUITING | PHASE2

68 participants

Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-09-12
Completion:: 2027-06-01

Conditions

Targeted Therapy
IDH1-Mutated Malignancies
Mutations

Interventions

DRUG

No Results Yet

NCT07031245 | RECRUITING | NA

203 participants

Evidence-Based Quality Improvement to Reduce VA Primary Care Burnout

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-06-18
Completion:: 2028-09-30

Conditions

Burnout
Burnout Syndrome

Interventions

BEHAVIORAL

No Results Yet

NCT07029386 | RECRUITING | NA

40 participants

Effects of Transcranial Electrical Stimulation on Cognitive Impairment in CNS Inflammatory Demyelinating Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-12-15
Completion:: 2027-07-01

Conditions

Idiopathic Inflammatory Demyelinating Disorders of the Central Nervous System

Interventions

DEVICE

No Results Yet