Clinical Trials Updated in 2026

NCT06922539 | RECRUITING | PHASE1

44 participants

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-12-11
Completion:: 2027-05-01

Conditions

Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06922188 | RECRUITING

2460 participants

Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-31
Completion:: 2029-09-18

Conditions

Financial Hardship
Alzheimer's Disease (AD)
Alzheimer's Disease and Related Dementia (ADRD)

No Results Yet

NCT06916702 | SUSPENDED | PHASE1

100 participants

A Study to Test How Well Different Doses of BI 3031185 Are Tolerated by Healthy Men and Women

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-04-07
Completion:: 2026-10-07

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT06916078 | COMPLETED | PHASE1

30 participants

A Study of Lepodisiran (LY3819469) in Participants With Normal, Mild, Moderate, or Severe Liver Function

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-04-23
Completion:: 2026-07-13

Conditions

Liver Dysfunction
Healthy

Interventions

DRUG

No Results Yet

NCT06907875 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-05-08
Completion:: 2027-07-07

Conditions

Facioscapulohumeral Muscular Dystrophy

Interventions

BIOLOGICAL

No Results Yet

NCT06906120 | COMPLETED | NA

60 participants

The Effect of Operating Room Introduction With Virtual Reality Glasses on Anxiety, Surgical Fear, and Satisfaction Levels in Patients Undergoing Orthopedic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-07
Completion:: 2025-10-25

Conditions

Artroscopic Surgery
Orthopedic Surgery

Interventions

BEHAVIORAL

No Results Yet

NCT06898879 | RECRUITING | NA

119 participants

Enhancing Veteran-Clinical Collaboration in VA PRRCs

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-08-12
Completion:: 2028-04-03

Conditions

Schizophrenia
Schizoaffective Disorder
Delusional Disorder
Bipolar Disorder
Major Depressive Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06898099 | RECRUITING | NA

136 participants

Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-10-14
Completion:: 2027-10-14

Conditions

Chronic Insomnia

Interventions

OTHER

No Results Yet

NCT06894810 | RECRUITING | NA

358 participants

Investigating the Efficacy of a Paediatric Fertility Preservation Decision Aid in Parents and Adolescents and Young Adults (CAYA) Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-12-08
Completion:: 2027-06-30

Conditions

Unmet Fertility Information Needs

Interventions

OTHER

No Results Yet

NCT06891911 | RECRUITING | NA

150 participants

Groceries for Residents of Southeastern USA to Stop Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-10-14
Completion:: 2026-11-30

Conditions

Hypertension
Elevated Blood Pressure
Cardiovascular Diseases
Dietary Intervention

Interventions

BEHAVIORAL

No Results Yet

NCT06869551 | RECRUITING | PHASE3

60 participants

A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-13
Completion:: 2030-03-06

Conditions

Juvenile Psoriatic Arthritis

Interventions

DRUG
OTHER

No Results Yet

NCT06868719 | RECRUITING | NA

35 participants

Ketone Ester And Salt (KEAS) in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-06
Completion:: 2027-12-31

Conditions

Salt; Excess
Hypertension
Aging
Inflammation
Blood Pressure

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06868212 | RECRUITING | PHASE3

400 participants

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-11
Completion:: 2027-02-22

Conditions

Chronic Spontaneous Urticaria (CSU)

Interventions

DRUG

No Results Yet

NCT06865534 | COMPLETED | NA

70 participants

Large Language Models to Aid Gynecological Oncology Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-05-22
Completion:: 2026-08-06

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT06865222 | RECRUITING | NA

40 participants

Post COVID-19 Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-22
Completion:: 2027-01-31

Conditions

Post COVID-19 Condition

Interventions

PROCEDURE

No Results Yet

NCT06864312 | COMPLETED | PHASE4

120 participants

Rebound Pain Following Regional Anaesthesia for Ankle Fracture Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2023-10-16
Completion:: 2025-01-28

Conditions

Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)
Ankle Fracture - Lateral Malleolus
Ankle Fracture - Medial Malleolus
Rebound Pain

Interventions

DRUG

No Results Yet

NCT06862115 | COMPLETED | PHASE3

182 participants

The Effect of Discontinuation of Renin Angiotensin System Inhibitors on the Perioperative Myocardial Injury in Adult Patients Undergoing Colorectal Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-01
Completion:: 2026-08-10

Conditions

Myocardium; Injury
Perioperative/Postoperative Complications
Angiotensin-Converting-Enzyme Inhibitor

Interventions

DRUG

No Results Yet

NCT06860529 | RECRUITING | PHASE2

357 participants

Serplulimab Combined With Chemotherapy for Early-stage HR+/HER2- Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-04-15
Completion:: 2028-03-31

Conditions

HR+/HER2- Breast Cancer

Interventions

DRUG

No Results Yet

NCT06859801 | RECRUITING

120 participants

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-10-23
Completion:: 2027-07-31

Conditions

Bone Cancer Metastatic

Interventions

DEVICE
RADIATION

No Results Yet

NCT06848231 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-03
Completion:: 2027-06-30

Conditions

Multiple System Atrophy

Interventions

DRUG

No Results Yet

NCT06842732 | RECRUITING | NA

776 participants

A Trial Testing a Two-way SMS Platform to Recognize and Prevent Wasting Among HIV-infected and HIV-exposed Uninfected Children in Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-06-05
Completion:: 2027-05-05

Conditions

Malnutrition in Children
Children Exposed to HIV

Interventions

BEHAVIORAL

No Results Yet

NCT06832618 | ACTIVE_NOT_RECRUITING | PHASE3

159 participants

A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-06-17
Completion:: 2026-08-07

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06829784 | RECRUITING | PHASE3

660 participants

TQC2731 Clinical Trial for the Treatment of Severe Asthma With Injection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-21
Completion:: 2027-12-31

Conditions

Asthma

Interventions

DRUG

No Results Yet

NCT06817005 | COMPLETED | NA

50 participants

Nociception Monitoring During Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-18
Completion:: 2026-06-01

Conditions

Nociception
NOL Index
Cardiac Surgery

Interventions

DEVICE

No Results Yet

NCT06816927 | RECRUITING | PHASE2

92 participants

Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-11-28
Completion:: 2029-06-01

Conditions

Newly Diagnosed Glioblastoma

Interventions

DRUG
RADIATION

No Results Yet

NCT06811545 | NOT_YET_RECRUITING | NA

65 participants

Evaluating the Effects of an Electrical Stimulator on Improving the Walking Ability of Children With Cerebral Palsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-09-30
Completion:: 2029-06-30

Conditions

Cerebral Palsy Children
Healthy Adults

Interventions

DEVICE

No Results Yet

NCT06808490 | COMPLETED | NA

68 participants

Exercise and Endocannabinoids for Brain and Mental Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-12-21
Completion:: 2024-03-18

Conditions

Children
Adolescents

Interventions

BEHAVIORAL

No Results Yet

NCT06807970 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

54 participants

Optimization of Obesity for Total Knee Replacement With Glucagon-like Peptide-1 Receptor Agonist

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-09-01
Completion:: 2027-07-01

Conditions

Osteoarthritis (OA) of the Knee

Interventions

DRUG
OTHER

No Results Yet

NCT06805656 | RECRUITING | PHASE2

70 participants

Multi Interventional Approaches to Mitigate HIV Reservoirs for the Sustained HIV Remission Without Antiretrovirals

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-07-15
Completion:: 2027-03-01

Conditions

Hiv
HIV I Infection

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06800794 | ACTIVE_NOT_RECRUITING | NA

12 participants

Investigating Metabolic and Psychological Adaptations in a Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-07-16
Completion:: 2026-06-30

Conditions

Obesity and Type 2 Diabetes

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06800716 | RECRUITING

50 participants

Impella Reverse Remodeling in End-Stage Heart Failure

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-12-04
Completion:: 2028-11-30

Conditions

Heart Failure
Cardiomyopathy

No Results Yet

NCT06792253 | RECRUITING | PHASE3

416 participants

Study Comparing BEBT-908 Combined With R to SOC for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-01-06
Completion:: 2028-12-31

Conditions

Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Interventions

DRUG

No Results Yet

NCT06789445 | RECRUITING | PHASE1/PHASE2

54 participants

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-10
Completion:: 2029-10-31

Conditions

Primary Photoreceptor Disease
Retinitis Pigmentosa (RP)
Usher Syndrome
Inherited Retinal Disease (IRD)
Rod-Cone Dystrophy
Rod-Cone Disease
Retinal Degeneration
Cone-Rod Disease (C-RD)
Cone-Rod Dystrophy

Interventions

BIOLOGICAL

No Results Yet

NCT06788678 | RECRUITING | NA

250 participants

A Randomized Controlled Trial of a Web-Based Moral Elevation Intervention for Veterans With PTSD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-08-10
Completion:: 2029-06-30

Conditions

Posttraumatic Stress Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06782373 | ACTIVE_NOT_RECRUITING | PHASE2

78 participants

A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-05-28
Completion:: 2026-12-30

Conditions

VEXAS
VEXAS Syndrome

Interventions

DRUG

No Results Yet

NCT06781359 | RECRUITING

200 participants

Study on Plasmablastic Lymphoma Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-02-14
Completion:: 2028-02-01

Conditions

Plasmablastic Lymphoma

No Results Yet

NCT06771856 | RECRUITING | NA

129 participants

Time to Step Up to Stepped Care: A Novel Strategy for Cognitive Behavioral Therapy for Insomnia in Chronic Spinal Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-02-01
Completion:: 2027-12-31

Conditions

Chronic Spinal Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06767514 | RECRUITING | PHASE3

780 participants

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-02-27
Completion:: 2028-04-30

Conditions

Non-Small Cell Lung Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06759012 | COMPLETED | NA

269 participants

An Agentic Co-educator System for Personalized Medical Education

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2025-03-02
Completion:: 2026-06-15

Conditions

Medical Education

Interventions

OTHER

No Results Yet

NCT06758622 | ACTIVE_NOT_RECRUITING

40000 participants

Analysis on the Health of Newborns in Three Hospitals, 2008-2024

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2024-11-09
Completion:: 2025-11-12

Conditions

Neonatal Morbidity and Mortality
Intrauterine Growth Disorders (IUGR and Macrosomia)
Prematurity Complications
Neonatal Infections

No Results Yet