Clinical Trials

NCT04406818 | ACTIVE_NOT_RECRUITING | NA

120 participants

Metabolic and Hemodynamic Reserve in Pediatric SCA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-06-30

Completion:

2027-03-31

Conditions

• Child, Only
• Brain Diseases
• Sickle Cell Disease
• Anemia, Sickle Cell

Interventions

• DRUG

No Results Yet

NCT04383275 | ACTIVE_NOT_RECRUITING | PHASE2

367 participants

Stage I HER2 Positive Invasive Breast Cancer De-escalation Study(IRIS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2020-05-20

Completion:

2031-07-06

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04375332 | ACTIVE_NOT_RECRUITING | NA

25 participants

Beating Heart Mitral Valve Repair With the HARPOON™ System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2020-12-16

Completion:

2027-12-20

Conditions

• Mitral Regurgitation

Interventions

• DEVICE

No Results Yet

NCT04373317 | RECRUITING | PHASE4

358 participants

Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-10-24

Completion:

2027-10-24

Conditions

• Parkinson's Disease Psychosis

Interventions

• DRUG

No Results Yet

NCT04370054 | ACTIVE_NOT_RECRUITING | PHASE3

77 participants

Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2020-08-18

Completion:

2024-06-17

Conditions

• Hemophilia A

Interventions

• BIOLOGICAL

Results Available

NCT04339777 | RECRUITING | PHASE2

66 participants

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2020-09-22

Completion:

2026-10-01

Conditions

• Lymphoproliferative Disorders
• Autoimmune Lymphoproliferative
• Immune System Diseases
• Common Variable Immunodeficiency
• Primary T-cell Immunodeficiency Disorders

Interventions

• DRUG
• RADIATION
• PROCEDURE

No Results Yet

NCT04179032 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-11-28

Completion:

2023-01-16

Conditions

• Systemic Lupus Erythematosus

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04157049 | RECRUITING

5000 participants

Alpha-1 Research Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2019-06-20

Completion:

2029-06-20

Conditions

• Alpha 1-Antitrypsin Deficiency

No Results Yet

NCT04136054 | COMPLETED | NA

131 participants

Better Sleep in Psychiatric Care - Depression, Anxiety and PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-09-25

Completion:

2024-02-06

Conditions

• Sleep Problem
• Anxiety Disorders
• Affective Disorder

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04104776 | RECRUITING | PHASE1/PHASE2

300 participants

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-09-18

Completion:

2030-02-27

Conditions

• Advanced Solid Tumor
• Diffuse Large B Cell Lymphoma
• Lymphoma, T-Cell
• Mesothelioma, Malignant
• Prostatic Neoplasms, Castration-Resistant
• Endometrial Cancer
• Ovarian Clear Cell Carcinoma
• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04092283 | ACTIVE_NOT_RECRUITING | PHASE3

660 participants

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2020-04-29

Completion:

2028-12-31

Conditions

• Recurrent Lung Non-Small Cell Carcinoma
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Unresectable Lung Non-Small Cell Carcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04091464 | COMPLETED | NA

90 participants

TRAIN-BW: Backward Walking Training in Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2020-01-01

Completion:

2026-05-30

Conditions

• Multiple Sclerosis
• Gait Disorders, Neurologic
• Accidental Fall

Interventions

• BEHAVIORAL

No Results Yet

NCT04077762 | RECRUITING | NA

3266 participants

Radial vs. State-Of-The-Art Femoral Access for Bleeding and Access Site Complication Reduction in Cardiac Catheterization (REBIRTH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-11-15

Completion:

2027-08-19

Conditions

• Patient Satisfaction
• Vascular Access Complication

Interventions

• PROCEDURE

No Results Yet

NCT03981666 | COMPLETED | NA

177 participants

Video-Based Cognitive Behavioral Therapy for Insomnia in Adults Cancer Patients and Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2018-05-04

Completion:

2018-06-29

Conditions

• Insomnia

Interventions

• OTHER

No Results Yet

NCT03959891 | ACTIVE_NOT_RECRUITING | PHASE1

77 participants

AKT Inhibitor, Ipatasertib, With Endocrine and CDK 4/6 Inhibitor for Patients With Metastatic Breast Cancer (TAKTIC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-05-30

Completion:

2022-12-25

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT03937635 | RECRUITING | PHASE3

288 participants

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-09-16

Completion:

2029-12-31

Conditions

• Smoldering Plasma Cell Myeloma

Interventions

• BIOLOGICAL
• DRUG
• OTHER

No Results Yet

NCT03910569 | RECRUITING

1000 participants

The Cedars-Sinai Smidt Heart Institute Takotsubo Registry & Proteomic Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2019-01-03

Completion:

2029-02-28

Conditions

• Takotsubo Cardiomyopathy

No Results Yet

NCT03876769 | ACTIVE_NOT_RECRUITING | PHASE2

121 participants

Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-06-24

Completion:

2027-10-19

Conditions

• B-Cell Acute Lymphoblastic Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT03803943 | COMPLETED | PHASE2

210 participants

Early Communication Intervention for Toddlers With Hearing Loss

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-06-15

Completion:

2023-05-16

Conditions

• Hearing Loss, Bilateral

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT03782493 | COMPLETED | PHASE2

108 participants

Maximizing Outcomes for Preschoolers With Developmental Language Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-04-04

Completion:

2025-02-22

Conditions

• Developmental Language Disorder

Interventions

• BEHAVIORAL

Results Available

NCT03750227 | RECRUITING | PHASE3

140 participants

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2018-11-19

Completion:

2030-11-08

Conditions

• Malignant Solid Neoplasm
• Metastatic Malignant Neoplasm in the Brain

Interventions

• PROCEDURE
• OTHER
• RADIATION

No Results Yet

NCT03740165 | COMPLETED | PHASE3

1367 participants

Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2018-12-18

Completion:

2024-08-26

Conditions

• Ovarian Cancer
• Fallopian Tube Cancer
• Peritoneal Neoplasms

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03661255 | COMPLETED | NA

1427 participants

Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-09-12

Completion:

2025-02-18

Conditions

• Suicide

Interventions

• BEHAVIORAL

Results Available

NCT03655665 | TERMINATED | PHASE4

9 participants

Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-05-16

Completion:

2024-06-01

Conditions

• Otitis Media

Interventions

• DRUG

Results Available

NCT03606070 | TERMINATED | NA

11 participants

Multiparametric PET-MRI Integration for a New Approach to Tumor Heterogeneity in Non-Small Cell Lung Cancer (NSCLC): Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2017-11-25

Completion:

2019-08-29

Conditions

• NSCLC

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03604315 | RECRUITING | PHASE1

300 participants

Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTF

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2018-12-18

Completion:

2027-06-30

Conditions

• Breast Carcinoma
• Fallopian Tube Carcinoma
• Ovarian Carcinoma
• Primary Peritoneal Carcinoma
• Recurrent Fallopian Tube Carcinoma
• Recurrent Ovarian Carcinoma
• Recurrent Primary Peritoneal Carcinoma
• Solid Neoplasm

Interventions

• PROCEDURE
• RADIATION

No Results Yet

NCT03602820 | ACTIVE_NOT_RECRUITING

41 participants

Long-term Follow-up Study in Subjects Who Received Voretigene Neparvovec-rzyl (AAV2-hRPE65v2)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2015-06-30

Completion:

2030-01-31

Conditions

• Inherited Retinal Dystrophy Due to RPE65 Mutations

Interventions

• BIOLOGICAL

No Results Yet

NCT03586362 | COMPLETED

278 participants

Vancomycin De-escalation Therapy in Patients With Pneumonia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2018-02-08

Completion:

2023-09-11

Conditions

• Pneumonia

No Results Yet

NCT03493425 | ACTIVE_NOT_RECRUITING | PHASE2

82 participants

Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2019-03-12

Completion:

2029-03-31

Conditions

• Stage III Sinonasal Squamous Cell Carcinoma AJCC v6 and v7
• Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7

Interventions

• DRUG
• RADIATION
• OTHER
• PROCEDURE

No Results Yet

NCT03454035 | RECRUITING | PHASE1

45 participants

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2018-01-30

Completion:

2028-02-03

Conditions

• Tumor, Solid
• Pancreatic Cancer
• Melanoma

Interventions

• DRUG

No Results Yet

NCT03404388 | WITHDRAWN | NA

0 participants

Brain and Behavioral Influences on Motor Skill Learning in Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2020-04-01

Completion:

2026-08-17

Conditions

• Multiple Sclerosis

Interventions

• BEHAVIORAL

No Results Yet

NCT03376126 | COMPLETED

15 participants

Minimally-Invasive Isolated Limb Perfusion

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2016-06-01

Completion:

2026-06-15

Conditions

• Isolated Limb Perfusion

Interventions

• OTHER

No Results Yet

NCT03299530 | RECRUITING

70 participants

Accuracy of Corneal Astigmatism in Different Region Modes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2017-10-10

Completion:

2027-06-10

Conditions

• Astigmatism
• Cornea

Interventions

• OTHER

No Results Yet

NCT03236064 | TERMINATED | PHASE1

4 participants

Conversion of Seddon III Nerve Injury to Seddon I/II Nerve Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2016-05-31

Completion:

2022-11-30

Conditions

• Injury of Other Nerves at Wrist and Hand Level of Unspecified Arm, Initial Encounter

Interventions

• DRUG

No Results Yet

NCT03193970 | RECRUITING

2000 participants

Measuring Surgical Recovery After Radical Cystectomy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2015-04-30

Completion:

2034-12-31

Conditions

• Bladder Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT03192410 | ACTIVE_NOT_RECRUITING

4837 participants

Prospective Cohort Study of 4,837 Post-myocardial Infarction Patients (Alpha Omega Cohort)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2002-04-30

Completion:

2040-01-31

Conditions

• Cardiovascular Diseases
• Mortality
• Type 2 Diabetes Mellitus
• Cognitive Decline
• Mental Well-being
• Kidney Function

Interventions

• BEHAVIORAL
• BIOLOGICAL
• GENETIC

No Results Yet

NCT03178630 | RECRUITING

150 participants

MRI Biomarkers in as Predictor of Clinical Endpoints in Pediatric Autoimmune Liver Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2017-02-20

Completion:

2030-02-28

Conditions

• Autoimmune Liver Disease
• Autoimmune Hepatitis
• Primary Sclerosing Cholangitis

No Results Yet

NCT03175471 | RECRUITING

115 participants

MRI Based Biomarkers in Pediatric Autoimmune Liver Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2017-01-17

Completion:

2030-01-30

Conditions

• Autoimmune Liver Disease
• Primary Sclerosing Cholangitis
• Autoimmune Hepatitis

No Results Yet

NCT03147612 | ACTIVE_NOT_RECRUITING | PHASE2

22 participants

Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2018-02-08

Completion:

2027-02-28

Conditions

• Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia With BCR-ABL1
• Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
• Recurrent Acute Lymphoblastic Leukemia
• Refractory Acute Lymphoblastic Leukemia

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03105895 | ACTIVE_NOT_RECRUITING

200 participants

Prevention of Incisional Hernia With an Onlay Mesh Visible on MRI

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2017-09-01

Completion:

2022-06-01

Conditions

• Incisional Hernia

Interventions

• PROCEDURE

No Results Yet