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Clinical Trials

Showing trials with last updates posted in 2026.

NCT04104776 | RECRUITING | PHASE1/PHASE2
300 participants

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2019-09-18
Completion:
2030-02-27
Conditions
  • Advanced Solid Tumor
  • Diffuse Large B Cell Lymphoma
  • Lymphoma, T-Cell
  • Mesothelioma, Malignant
  • Prostatic Neoplasms, Castration-Resistant
  • Endometrial Cancer
  • Ovarian Clear Cell Carcinoma
  • Metastatic Castration-resistant Prostate Cancer
Interventions
  • DRUG
No Results Yet
NCT03740165 | COMPLETED | PHASE3
1367 participants

Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2018-12-18
Completion:
2024-08-26
Conditions
  • Ovarian Cancer
  • Fallopian Tube Cancer
  • Peritoneal Neoplasms
Interventions
  • BIOLOGICAL
  • DRUG
Results Available
NCT03604315 | RECRUITING | PHASE1
300 participants

Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTF

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2018-12-18
Completion:
2027-06-30
Conditions
  • Breast Carcinoma
  • Fallopian Tube Carcinoma
  • Ovarian Carcinoma
  • Primary Peritoneal Carcinoma
  • Recurrent Fallopian Tube Carcinoma
  • Recurrent Ovarian Carcinoma
  • Recurrent Primary Peritoneal Carcinoma
  • Solid Neoplasm
Interventions
  • PROCEDURE
  • RADIATION
No Results Yet
NCT03493425 | ACTIVE_NOT_RECRUITING | PHASE2
82 participants

Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2019-03-12
Completion:
2029-03-31
Conditions
  • Stage III Sinonasal Squamous Cell Carcinoma AJCC v6 and v7
  • Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
Interventions
  • DRUG
  • RADIATION
  • OTHER
  • PROCEDURE
No Results Yet
NCT03147612 | ACTIVE_NOT_RECRUITING | PHASE2
22 participants

Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2018-02-08
Completion:
2027-02-28
Conditions
  • Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Acute Lymphoblastic Leukemia
  • Acute Myeloid Leukemia With BCR-ABL1
  • Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Recurrent Acute Lymphoblastic Leukemia
  • Refractory Acute Lymphoblastic Leukemia
Interventions
  • BIOLOGICAL
  • DRUG
No Results Yet
NCT03025256 | ACTIVE_NOT_RECRUITING | PHASE1
75 participants

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2018-05-02
Completion:
2027-06-01
Conditions
  • Acral Lentiginous Melanoma
  • Central Nervous System Melanoma
  • Clinical Stage IV Cutaneous Melanoma AJCC v8
  • Leptomeningeal Neoplasm
  • Melanocytoma
  • Metastatic Lung Non-Small Cell Carcinoma
  • Metastatic Melanoma
  • Metastatic Mucosal Melanoma
  • Metastatic Uveal Melanoma
  • Stage IV Lung Cancer AJCC v8
Interventions
  • PROCEDURE
  • BIOLOGICAL
No Results Yet
NCT03007147 | ACTIVE_NOT_RECRUITING | PHASE3
352 participants

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2017-08-08
Completion:
2026-06-30
Conditions
  • Acute Lymphoblastic Leukemia
  • B Acute Lymphoblastic Leukemia
  • Mixed Phenotype Acute Leukemia
  • T Acute Lymphoblastic Leukemia
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
  • OTHER
No Results Yet
NCT02734537 | RECRUITING | PHASE2
189 participants

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2016-11-23
Completion:
2027-12-31
Conditions
  • Head and Neck Squamous Cell Carcinoma
  • Hypopharyngeal Squamous Cell Carcinoma
  • Laryngeal Squamous Cell Carcinoma
  • Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant
  • Lip and Oral Cavity Squamous Cell Carcinoma
  • p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma
  • Stage III Hypopharyngeal Carcinoma AJCC v8
  • Stage III Laryngeal Cancer AJCC v8
  • Stage III Lip and Oral Cavity Cancer AJCC v8
  • Stage III Oral Cavity Verrucous Carcinoma
  • Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
  • Stage IVA Hypopharyngeal Carcinoma AJCC v8
  • Stage IVA Laryngeal Cancer AJCC v8
  • Stage IVA Lip and Oral Cavity Cancer AJCC v8
  • Stage IVA Oral Cavity Verrucous Carcinoma
  • Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
  • DRUG
  • RADIATION
  • OTHER
No Results Yet
NCT02689440 | ACTIVE_NOT_RECRUITING | PHASE2
155 participants

Dasatinib and Venetoclax in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous Leukemia

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-19
Start Date:
2016-02-19
Completion:
2040-12-31
Conditions
  • Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Philadelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous Leukemia
Interventions
  • DRUG
  • OTHER
No Results Yet
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