Clinical Trials Updated in 2026

NCT06731907 | RECRUITING | PHASE2

90 participants

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-30
Completion:: 2032-03-12

Conditions

Non-small Cell Lung Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06728072 | RECRUITING | PHASE2

97 participants

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-07
Completion:: 2035-07-01

Conditions

Colorectal Cancer
CRC

Interventions

DRUG

No Results Yet

NCT06720090 | RECRUITING | EARLY_PHASE1

40 participants

Light Therapy for Obsessive-compulsive Disorder (OCD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-12-16
Completion:: 2029-03-31

Conditions

OCD

Interventions

BEHAVIORAL

No Results Yet

NCT06717178 | COMPLETED

360 participants

Cancer and Aging Research Group (CARG) Chemotherapy Toxicity Risk Scores in Older Adults With Cancer in China

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-12-24
Completion:: 2025-12-31

Conditions

Cancer
Cancer-related Problem/Condition

Interventions

DRUG

No Results Yet

NCT06702592 | NOT_YET_RECRUITING | NA

360 participants

Virtual Testis Cancer Lay Support and Survivorship Aim 2

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2026-09-30
Completion:: 2028-06-30

Conditions

Testicular Cancer
Testis Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06700538 | RECRUITING | PHASE1/PHASE2

180 participants

A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-12-04
Completion:: 2027-09-17

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06691035 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-11-04
Completion:: 2026-11-30

Conditions

Breast Cancer Metastatic Breast Cancer
HER2-negative Breast Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06685796 | COMPLETED | PHASE2

65 participants

A Study of BEBT-209 in Combination With Chemotherapy for the Treatment of Advanced Triple-Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-04-12
Completion:: 2026-04-20

Conditions

Advanced Triple-Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT06675903 | RECRUITING

54 participants

Continuous Glucose Monitoring (CGM) After Kidney Transplantation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-11-12
Completion:: 2027-01-01

Conditions

Hyperglycaemia
Kidney Transplantation

No Results Yet

NCT06667037 | ACTIVE_NOT_RECRUITING | NA

112 participants

Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-09-21
Completion:: 2026-12-31

Conditions

Myopia

Interventions

DEVICE
DRUG

No Results Yet

NCT06666673 | RECRUITING | EARLY_PHASE1

64 participants

Effect of Neural Constraints on Movement in Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-08-23
Completion:: 2029-06-30

Conditions

Stroke

Interventions

DRUG

No Results Yet

NCT06660017 | NOT_YET_RECRUITING | PHASE2

62 participants

Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2026-09-30
Completion:: 2027-06-30

Conditions

Head and Neck Cancer

Interventions

DRUG

No Results Yet

NCT06656494 | RECRUITING | PHASE1

266 participants

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-12-18
Completion:: 2027-06-30

Conditions

Acute Myelogenous Leukemia
Myelodysplastic Syndromes (MDS)

Interventions

DRUG

No Results Yet

NCT06650527 | RECRUITING | NA

118 participants

Effect of Cognitive Empathy Training on Dementia Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-13
Completion:: 2028-11-01

Conditions

Caregivers of People Living With Dementia
Dementia

Interventions

BEHAVIORAL
PROCEDURE

No Results Yet

NCT06640075 | ACTIVE_NOT_RECRUITING | NA

800 participants

Community Co-produced Action for Improved Access to Cervical Cancer Screening in Cameroon

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-04-13
Completion:: 2026-05-21

Conditions

Cervical Cancer Screening

Interventions

OTHER

No Results Yet

NCT06636058 | RECRUITING | NA

440 participants

Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-01-21
Completion:: 2028-04-14

Conditions

Obesity
Depression

Interventions

BEHAVIORAL

No Results Yet

NCT06627751 | RECRUITING | PHASE2

28 participants

Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma in Patients With Extramedullary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-05-01
Completion:: 2027-05-01

Conditions

Extramedullary Disease in Multiple Myeloma
Recurrent Multiple Myeloma
Refractory Multiple Myeloma

Interventions

BIOLOGICAL
DRUG
PROCEDURE

No Results Yet

NCT06626230 | RECRUITING | PHASE1

48 participants

Safety of Anal Curcumin

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-17
Completion:: 2026-12-31

Conditions

Anal High Grade Squamous Intraepithelial Lesion

Interventions

DRUG

No Results Yet

NCT06625411 | ACTIVE_NOT_RECRUITING | PHASE3

132 participants

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-08-27
Completion:: 2026-02-12

Conditions

Thyroid Eye Disease

Interventions

DRUG

No Results Yet

NCT06625398 | ACTIVE_NOT_RECRUITING | PHASE3

204 participants

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-08-27
Completion:: 2026-03-04

Conditions

Thyroid Eye Disease

Interventions

DRUG

No Results Yet

NCT06623435 | COMPLETED

1075 participants

Real World and Genomic Data Based Asthma Insight Through Network Analysis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2019-11-07
Completion:: 2025-06-16

Conditions

Asthma

No Results Yet

NCT06621329 | RECRUITING | PHASE2/PHASE3

40 participants

Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-10-17
Completion:: 2027-07-31

Conditions

SAH (Subarachnoid Hemorrhage)
Headache

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06620458 | ENROLLING_BY_INVITATION

5000 participants

Influencing Factors and Outcomes of DCB Angioplasty

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-10-01
Completion:: 2025-12-01

Conditions

Coronary Artery Disease

No Results Yet

NCT06618287 | RECRUITING | PHASE1/PHASE2

416 participants

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-04
Completion:: 2031-02-26

Conditions

Lung Cancer
Breast Cancer

Interventions

DRUG

No Results Yet

NCT06615479 | RECRUITING | PHASE3

440 participants

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-12
Completion:: 2027-12-30

Conditions

Relapsed or Refractory Multiple Myeloma (RRMM)

Interventions

DRUG

No Results Yet

NCT06602219 | COMPLETED | PHASE2

222 participants

A Study of LY4100511 (DC-853) in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-10-25
Completion:: 2025-07-24

Conditions

Plaque Psoriasis

Interventions

DRUG

Results Available

NCT06594068 | RECRUITING | PHASE4

16 participants

Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in Anifrolumab Users

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2026-01-16
Completion:: 2027-08-31

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT06593106 | ACTIVE_NOT_RECRUITING | NA

13 participants

Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-09-27
Completion:: 2026-12-30

Conditions

Stage I Lung Cancer
Stage II Lung Cancer

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06581263 | COMPLETED

10 participants

Psychedelic Virtual Reality

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-07-22
Completion:: 2026-03-22

Conditions

Psychedelic Experiences
Virtual Reality
Healthy Volunteer

Interventions

DEVICE

No Results Yet

NCT06568484 | RECRUITING | PHASE2/PHASE3

2530 participants

Bedaquiline Roll-out Evidence in Contacts and People Living With HIV to Prevent TB

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2026-05-08
Completion:: 2027-07-31

Conditions

Tuberculosis, Latent

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT06564844 | ACTIVE_NOT_RECRUITING | PHASE3

25 participants

A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological Features

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-10-15
Completion:: 2027-06-30

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06559228 | ACTIVE_NOT_RECRUITING | PHASE2

400 participants

ConnectedNest: a Digital Platform Connecting Individuals With Cancer to Social Care

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-06-12
Completion:: 2026-08-31

Conditions

Cancer

Interventions

OTHER

No Results Yet

NCT06559163 | ACTIVE_NOT_RECRUITING | PHASE2

190 participants

A Study of Obexelimab in Patients With Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-09-17
Completion:: 2026-09-30

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT06522880 | WITHDRAWN

0 participants

Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-08-10
Completion:: 2027-01-31

Conditions

Cytomegalovirus Infections

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06518473 | COMPLETED

100 participants

Atopy and Frequency of Exacerbation in Chronic Obstructive Pulmonary Disease Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-07-14
Completion:: 2025-09-15

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06514027 | RECRUITING | PHASE2

30 participants

Study of BEBT-109 in Subjects With Non-Small Cell Lung Cancer Carrying EGFR Exon 20 Insertion Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-08-28
Completion:: 2027-06-30

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06507579 | RECRUITING

250 participants

Hydra Registry - UK

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-07-11
Completion:: 2027-07-11

Conditions

Aortic Valve Stenosis

Interventions

DEVICE

No Results Yet

NCT06489886 | ACTIVE_NOT_RECRUITING | NA

19 participants

Nutrient and Hormonal Profile and Muscle Protein Synthesis Response to Consuming Chicken

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-10-11
Completion:: 2026-10-01

Conditions

Effect of Food

Interventions

OTHER

No Results Yet

NCT06484153 | RECRUITING | PHASE2

25 participants

Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-07-22
Completion:: 2026-07-22

Conditions

To Evaluate the Efficacy of Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Colorectal Carcinoma
To Evaluate Whether Pirfenidone Can Reshape the Tumor Microenvironment in Colorectal Cancer
Combination of Fruquintinib and Anti-PD-1 Antibody Was Reported to Improve Patient Prognosis in Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06484075 | RECRUITING | PHASE1/PHASE2

180 participants

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-11-21
Completion:: 2028-12-31

Conditions

Healthy Volunteers
Alcohol Use Disorder (AUD)

Interventions

DRUG

No Results Yet