Clinical Trials Updated in 2026

NCT07476287 | RECRUITING | PHASE2

40 participants

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-07-02
Completion:: 2028-03-19

Conditions

Small Cell Lung Cancer
Small Cell Lung Cancer ( SCLC )
Transformed Small Cell Lung Cancer
Lung Neoplasms
Carcinoma, Small Cell Lung
Small Cell Cancer Of The Lung

Interventions

DRUG

No Results Yet

NCT07474376 | RECRUITING | NA

30 participants

Diabetes Multimorbidity Typology, Trajectory, and Feasibility of an Audio Diary Mobile Application to Support Self-management

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-09-30
Completion:: 2027-03-31

Conditions

Diabetes Mellitus, Type 2
Diabetes Mellitus, Type 1

Interventions

OTHER

No Results Yet

NCT07464353 | RECRUITING | NA

30 participants

xDot Access Management System Early Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-06-16
Completion:: 2026-08-31

Conditions

Vascular Closure Devices

Interventions

DEVICE

No Results Yet

NCT07456033 | RECRUITING | PHASE3

456 participants

A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-13
Completion:: 2030-09-23

Conditions

Asthma

Interventions

DRUG

No Results Yet

NCT07453602 | RECRUITING | PHASE1

125 participants

Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-02
Completion:: 2028-04-30

Conditions

Atopic Dermatitis (AD)
Eczema

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07448597 | RECRUITING | PHASE4

642 participants

Progesterone Preeclampsia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-13
Completion:: 2028-08-01

Conditions

Preeclampsia
Hypertensive Disorder of Pregnancy

Interventions

DRUG

No Results Yet

NCT07441863 | COMPLETED

60 participants

Structured Pulmonary Physiotherapy After Lung Cancer Surgery by Age Group

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-01
Completion:: 2026-03-02

Conditions

Lung Cancer
Postoperative Pulmonary Complications

Interventions

BEHAVIORAL

No Results Yet

NCT07441681 | RECRUITING | PHASE3

454 participants

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-07-31
Completion:: 2035-11-30

Conditions

Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Head and Neck Squamous Cell Carcinoma
Stage III Hypopharyngeal Carcinoma AJCC v8
Stage III Laryngeal Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVA Hypopharyngeal Carcinoma AJCC v8
Stage IVA Laryngeal Cancer AJCC v8
Stage IVA Lip and Oral Cavity Cancer AJCC v8
Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVB Hypopharyngeal Carcinoma AJCC v8
Stage IVB Laryngeal Cancer AJCC v8
Stage IVB Lip and Oral Cavity Cancer AJCC v8
Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL
RADIATION
OTHER

No Results Yet

NCT07440290 | RECRUITING | PHASE2/PHASE3

30 participants

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-04-01
Completion:: 2029-10-31

Conditions

Haematological Malignancy
Malignant Neoplasm
Lymphoproliferative Disorders
Neoplasms by Histologic Type
Neoplasms by Site
Gastrointestinal Cancer
Non-Melanoma Skin Cancer (NMSC)
Langerhans Cell Histiocytosis (LCH)
Cancer
Erdheim-Chester Disease
Thyroid Carcinoma, Papillary
Ovarian Neoplasms
Colorectal Neoplasms
Laryngeal Neoplasms
Carcinoma, Non-Small Cell-Lung
Glioma
Multiple Myeloma
Thyroid Carcinoma, Anaplastic
Solid Tumour
Pancreatic Diseases

Interventions

DRUG

No Results Yet

NCT07439471 | RECRUITING

40 participants

Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-09-28
Completion:: 2027-03-31

Conditions

Cigarette Smoking-Related Carcinoma

Interventions

OTHER

No Results Yet

NCT07432880 | RECRUITING

30 participants

A Prospective Study of Pediatric Participants up to 16 Years of Age With Methylmalonic Acidemia (MMA) Due to Mutations in the MMUT Gene

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-13
Completion:: 2030-08-31

Conditions

Methylmalonic Acidemia (MMA)

No Results Yet

NCT07430735 | RECRUITING | NA

35 participants

BriTer Eyez Moisture Vue™ On-Demand Disposable Moisture Chamber

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-31
Completion:: 2027-07-01

Conditions

Dry Eye Disease (DED)

Interventions

DEVICE

No Results Yet

NCT07430371 | ACTIVE_NOT_RECRUITING | NA

30 participants

Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-11
Completion:: 2026-11-30

Conditions

Direct Care Workers
Dementia Caregiver
In-Home Care
Caregiver Social Support
Peer Support

Interventions

BEHAVIORAL

No Results Yet

NCT07422285 | COMPLETED | PHASE1

405 participants

Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body After a Single Subcutaneous Dose

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-16
Completion:: 2026-07-24

Conditions

Healthy Participants
Pharmacokinetics

Interventions

DRUG

No Results Yet

NCT07421700 | RECRUITING | PHASE1/PHASE2

132 participants

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-11
Completion:: 2027-12-06

Conditions

Urothelial Cancer
Advanced/Metastatic Urothelial Cancer
Urothelial Carcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT07416214 | COMPLETED | NA

96 participants

Lactiplantibacillus Plantarum PD01 Supplementation Reduces Microplastics and Microplastic-associated Chemicals in Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-30
Completion:: 2026-01-12

Conditions

Intestinal Functional Disorder
Inflammation

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07414030 | COMPLETED

50 participants

Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-07-01
Completion:: 2024-09-30

Conditions

Severe Early Childhood Caries
Dental Caries

No Results Yet

NCT07412223 | RECRUITING | PHASE4

152 participants

Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-02-24
Completion:: 2026-12-01

Conditions

Pain, Postoperative
Postoperative Ileus

Interventions

DRUG

No Results Yet

NCT07404631 | COMPLETED | NA

56 participants

Effect of Intermittent Pneumatic Compression on Ankle Joint Proprioception and Balance in Patients With Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-02-12
Completion:: 2026-08-12

Conditions

Stroke

Interventions

DEVICE
OTHER

No Results Yet

NCT07401303 | RECRUITING | NA

640 participants

Full-time RDI for ESD: Impact on Major Adverse Events and Procedure Time

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-01
Completion:: 2027-12-31

Conditions

Early Gastric Cancer or Gastric Adenoma

Interventions

PROCEDURE

No Results Yet

NCT07400679 | COMPLETED | PHASE1

48 participants

A Study to Learn How the Study Medicine Called PF-08653944 is Taken up Into the Blood in Adults With Overweight or Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-02-04
Completion:: 2026-07-02

Conditions

Overweight
Obesity
Healthy

Interventions

DRUG

No Results Yet

NCT07395518 | ENROLLING_BY_INVITATION | NA

86 participants

A Randomized Controlled Trial Comparing the Incidence of Surgical Site Infections in Cesarean Section With and Without Subcutaneous Drain Placement at Queen Savang Vadhana Memorial Hospital

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-01
Completion:: 2026-05-01

Conditions

Surgical Site Infection (SSI)

Interventions

DEVICE

No Results Yet

NCT07392892 | RECRUITING | PHASE2/PHASE3

840 participants

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-14
Completion:: 2031-07-22

Conditions

Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma
Metastatic Gastric Cancer
Gastroesophageal Junction Cancer
Esophageal Adenocarcinoma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07391605 | RECRUITING | PHASE2

60 participants

Descartes-08 in Autoantibody Myositis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-04-28
Completion:: 2027-11-30

Conditions

Antisynthetase Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT07387354 | WITHDRAWN | PHASE1/PHASE2

0 participants

Pacritinib With Aza for Upfront Myelodysplastic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-09-30
Completion:: 2027-01-31

Conditions

Myelodysplastic Syndromes
MDS
Myelodysplastic Syndrome, Unclassifiable
Hematologic Diseases
Bone Marrow Disease
Myeloproliferative Neoplasm

Interventions

DRUG
PROCEDURE
DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT07383558 | RECRUITING

48 participants

Effect of Additional Sural Nerve PRF in Chronic Heel Pain

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-01
Completion:: 2026-05-01

Conditions

Chronic Plantar Heel Pain
Plantar Fasciitis
Spur, Heel

Interventions

PROCEDURE

No Results Yet

NCT07379684 | RECRUITING | PHASE1

44 participants

A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-09-30
Completion:: 2027-02-28

Conditions

Surgical Wound Infection
Traumatic Wound Infection

Interventions

DRUG

No Results Yet

NCT07362797 | RECRUITING | NA

566 participants

Video-guided Versus Conventional Right-sided Double-Lumen Tubes for One-Lung Ventilation in Thoracoscopic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-30
Completion:: 2026-12-24

Conditions

Thoracoscopic Surgery
Double Lumen Tube Intubation
One-Lung Ventilation

Interventions

DEVICE

No Results Yet

NCT07360314 | RECRUITING | PHASE1

138 participants

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-02-13
Completion:: 2028-09-20

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT07355803 | TERMINATED | NA

22 participants

Define Final Selection Choice Criteria for a Coloplast Catheter Ensuring Highest Patient Satisfaction Via Surveys (EVA).

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-21
Completion:: 2026-08-05

Conditions

Neurogenic Bladder Disorder
Non-Neurogenic Bladder
Bladder Dysfunction
Urinary Retention

Interventions

OTHER

No Results Yet

NCT07355218 | RECRUITING | PHASE3

202 participants

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-04-01
Completion:: 2029-05-25

Conditions

Systematic Lupus Erythematosus
Cutaneous Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT07354724 | RECRUITING | PHASE1

32 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-12
Completion:: 2028-08-31

Conditions

Late-onset Pompe Disease

Interventions

DRUG

No Results Yet

NCT07344701 | RECRUITING

2951 participants

"Screening for Change: Early Risk Detection and Integrated Prevention for Diabetes and Cardiovascular Diseases in the Marche Region"

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-04-09
Completion:: 2026-12-31

Conditions

Cardiovascular Diseases
Diabetes Mellitus Type 2

Interventions

OTHER

No Results Yet

NCT07341867 | RECRUITING | PHASE1

90 participants

Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-07-30
Completion:: 2028-03-31

Conditions

Multiple Myeloma
Triple Negative Breast Cancer
Duffy Blood Group, Chemokine Receptor Gene Mutation
Duffy Blood Group, Chemokine Receptor Gene C.-67T>C

Interventions

DRUG

No Results Yet

NCT07341607 | COMPLETED | NA

188 participants

Nurse-Led Patient Education in ESWL Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-25
Completion:: 2026-01-01

Conditions

Urolithiasis
ESWL

Interventions

OTHER

No Results Yet

NCT07336147 | RECRUITING | PHASE2

45 participants

Dostarlimab, Cisplatin and Etoposide in Combination With Radiotherapy in Sandwich Sequence for Small Cell Neuroendocrine Cervical Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-22
Completion:: 2028-06-22

Conditions

Female

Interventions

DRUG

No Results Yet

NCT07331857 | RECRUITING | NA

20 participants

Digma System First in Human (FIH) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-25
Completion:: 2026-12-31

Conditions

Barrett's Esophagus (BE)

Interventions

DEVICE

No Results Yet

NCT07325916 | COMPLETED

76 participants

Relationship Between Serum Apolipoprotein Levels and Weight Loss in Patients Undergoing Sleeve Gastrectomy for Morbid Obesity

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-04-09
Completion:: 2026-04-09

Conditions

Morbid Obesity Requiring Bariatric Surgery

Interventions

PROCEDURE

No Results Yet

NCT07323654 | RECRUITING | PHASE2

264 participants

A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-28
Completion:: 2027-12-31

Conditions

Eosinophilic Asthma

Interventions

DRUG
OTHER

No Results Yet

NCT07322887 | RECRUITING | PHASE2

45 participants

A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-21
Completion:: 2027-05-01

Conditions

Parkinson's Disease (PD)

Interventions

DRUG

No Results Yet