Clinical Trials Updated in 2026

NCT07322887 | RECRUITING | PHASE2

45 participants

A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-21
Completion:: 2027-05-01

Conditions

Parkinson's Disease (PD)

Interventions

DRUG

No Results Yet

NCT07318233 | RECRUITING | NA

120 participants

Adaptive Self-Efficacy-Based AI Coaching for Cycling

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-15
Completion:: 2028-12-23

Conditions

Exercise Training
Exercise Behavior
Exercise Adherence Challenges
Motivation for Physical Activity
Motivational Enhancement

Interventions

BEHAVIORAL

No Results Yet

NCT07308977 | RECRUITING

150 participants

Practice of Assisted Vaginal Birth in Egypt

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-15
Completion:: 2027-01-15

Conditions

Vaginal Delivery

Interventions

OTHER

No Results Yet

NCT07302776 | RECRUITING | PHASE1

50 participants

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-07-21
Completion:: 2028-02-29

Conditions

GVHD
Hematopoietic Cell Transplantation (HCT)
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndromes
Myelofibrosis (MF)
Chronic Myeloid Leukemia (CML)
Chronic Myelomonocytic Leukemia (CMML)

Interventions

DRUG
OTHER

No Results Yet

NCT07300306 | COMPLETED

3379 participants

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-04
Completion:: 2026-06-23

Conditions

Sepsis
Septic Shock
Critical Illness
Organ Dysfunction

No Results Yet

NCT07290569 | ACTIVE_NOT_RECRUITING | PHASE2

160 participants

Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-03
Completion:: 2027-06-30

Conditions

Plaque Psoriasis

Interventions

DRUG
OTHER

No Results Yet

NCT07289464 | COMPLETED | PHASE1

48 participants

A Clinical Study of RSS0343 in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-08
Completion:: 2026-08-10

Conditions

Non-cystic Fibrosis Bronchiectasis

Interventions

DRUG

No Results Yet

NCT07286513 | ENROLLING_BY_INVITATION

200 participants

Persona SoluTion PPS Femur PMCF

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-02-26
Completion:: 2029-12-31

Conditions

Rhematoid Arthritis
Osteo Arthritis of the Knee
Traumatic Arthritis of Knee (Diagnosis)
Polyarthritis
Collagen Disorders
Avascular Necrosis of Femoral Condyle
Valgus Deformity
Varus Deformity
Flexion Deformity of Knee

Interventions

DEVICE

No Results Yet

NCT07285460 | RECRUITING | PHASE3

85 participants

A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-18
Completion:: 2029-08-04

Conditions

Hemophilia

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT07285239 | RECRUITING | PHASE3

500 participants

Belantamab Mafodotin or Daratumumab With Bortezomib, Lenalidomide and Dexamethasone for Newly Diagnosed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-09-30
Completion:: 2031-11-30

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT07282574 | RECRUITING | PHASE2

360 participants

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-10
Completion:: 2028-05-30

Conditions

Progressive Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT07282210 | RECRUITING | PHASE2

105 participants

Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-13
Completion:: 2029-01-31

Conditions

Sickle Cell Disease
Sickle Cell Anaemia
Sickle Cell Anemia

Interventions

DRUG

No Results Yet

NCT07281937 | COMPLETED | PHASE2

206 participants

A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-25
Completion:: 2026-07-23

Conditions

Obesity
Overweight

Interventions

DRUG

No Results Yet

NCT07270640 | RECRUITING | NA

81 participants

Lifestyle Intervention to Improve Twin Pregnancy Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-05
Completion:: 2027-06-30

Conditions

Twin Pregnancy, Dichorionic

Interventions

BEHAVIORAL

No Results Yet

NCT07267728 | COMPLETED | NA

40 participants

A Clinical Study to Assess the Effect of a Dietary Supplement on Menstrual Cycle Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-02-01
Completion:: 2025-07-01

Conditions

Premenstrual Syndrome
Menstrual Pain

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07266584 | RECRUITING | NA

5 participants

Restoration of Central Vision With PRIMA in Patients With Photoreceptor Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-04-22
Completion:: 2029-03-01

Conditions

Stargardt Disease
Retinitis Pigmentosa (RP)
Inherited Retinal Degeneration

Interventions

DEVICE

No Results Yet

NCT07263776 | ACTIVE_NOT_RECRUITING | PHASE3

692 participants

Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-05
Completion:: 2026-09-16

Conditions

Acute Ischemic Stroke

Interventions

DRUG

No Results Yet

NCT07261293 | RECRUITING | NA

34 participants

Effects of Blood Flow Restriction Aerobic Exercise on Inflammation, Hypoxia, Exercise Capacity, and Lung Function in COPD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-01
Completion:: 2026-06-01

Conditions

COPD (Chronic Obstructive Pulmonary Disease)

Interventions

BEHAVIORAL

No Results Yet

NCT07260240 | COMPLETED | NA

60 participants

Recovery Rate From Category II to Category I EFM Tracings in Pregnant Women Receiving Bolus vs Continuous Intravenous Fluid Administration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-10
Completion:: 2026-03-27

Conditions

Category II Fetal Heart Rate Tracing

Interventions

DRUG

No Results Yet

NCT07255807 | RECRUITING | NA

80 participants

Defining the Human Insulin Resistance Molecular Network; SIGNATURE

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-09
Completion:: 2028-06-30

Conditions

Metabolic Health
Insulin Sensitivity/Resistance

Interventions

BEHAVIORAL

No Results Yet

NCT07251894 | ENROLLING_BY_INVITATION | NA

85 participants

Pilot Study Exploring the Feasibility, Acceptability, and Impact of Medically Tailored Meals on Post-Discharge Recovery in Patients With Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-01
Completion:: 2029-09-30

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT07246031 | RECRUITING | PHASE2

50 participants

BPC2001 for the Prevention of Acute Graft-Versus-Host Disease Following Haploidentical Stem Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-29
Completion:: 2028-04-30

Conditions

Graft -Versus-host-disease
aGVHD
Haploidentical Stem Cell Transplantation
cGVHD

Interventions

DRUG

No Results Yet

NCT07243340 | RECRUITING | PHASE1/PHASE2

36 participants

A Phase I/IIa Study of C5252 in Patients With Intracranial Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-04-03
Completion:: 2027-12-15

Conditions

Glioma, Malignant

Interventions

BIOLOGICAL

No Results Yet

NCT07242469 | ACTIVE_NOT_RECRUITING | PHASE1

52 participants

A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-22
Completion:: 2026-09-03

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT07241286 | ENROLLING_BY_INVITATION

100 participants

Evaluation of the Effectiveness of Enhanced Recovery After Surgery (ERAS) Program in Pediatric Lung Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-05
Completion:: 2030-02-28

Conditions

Lung Surgery
Enhanced Recovery After Surgery, ERAS
Pediatric

Interventions

OTHER

No Results Yet

NCT07240259 | ENROLLING_BY_INVITATION | NA

5 participants

Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-12-01
Completion:: 2028-01-31

Conditions

Trachea Diseases
Tracheal Stenosis
Tuberculosis; Tracheitis
Airway Disease
Tracheomalacia
Tracheal Stenosis Following Tracheostomy
Tracheal Reconstruction Surgery

Interventions

PROCEDURE

No Results Yet

NCT07231653 | NOT_YET_RECRUITING

69 participants

Home Monitoring Study for Surgical Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2027-01-01
Completion:: 2028-12-31

Conditions

Patient Monitoring
Postoperative Period

Interventions

DEVICE

No Results Yet

NCT07228416 | COMPLETED | NA

20 participants

Milky Way Sensor Motion Validation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-02-05
Completion:: 2026-02-25

Conditions

Infiltration of Peripheral IV Therapy

Interventions

DEVICE

Results Available

NCT07227584 | RECRUITING | PHASE2

67 participants

ALL Backbone in AYAs

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-04-03
Completion:: 2030-07-31

Conditions

Acute Lymphoblastic Leukemia
Philadelphia Chromosome-Negative Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia (ALL)
Leukemia

Interventions

DRUG

No Results Yet

NCT07227012 | RECRUITING | PHASE1/PHASE2

138 participants

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-01
Completion:: 2027-10-18

Conditions

Carcinoma, Hepatocellular
Hepatocellular Cancer
Hepatocellular Carcinoma
Unresectable Hepatocellular Carcinoma
Liver Neoplasms
Advanced Hepatocellular Carcinoma
Metastatic Hepatocellular Carcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT07226999 | RECRUITING | PHASE2/PHASE3

550 participants

Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-09
Completion:: 2030-06-14

Conditions

Small Cell Lung Cancer (SCLC)

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT07226245 | WITHDRAWN | PHASE4

0 participants

Methadone Pharmacokinetics in Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-09-30
Completion:: 2026-12-30

Conditions

Postoperative Pain Management

Interventions

DRUG

No Results Yet

NCT07223021 | RECRUITING | PHASE3

65 participants

A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-20
Completion:: 2028-10-31

Conditions

B-cell Acute Lymphoblastic Leukemia

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT07222943 | RECRUITING | NA

63 participants

Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-09-01
Completion:: 2027-04-30

Conditions

Functional Abdominal Pain Disorders
Irritable Bowel Syndrome (IBS)
Functional Gastrointestinal Disorders (FGIDs)
Gastrointestinal and Digestive Disorder
Abdominal Pain/ Discomfort
Pain
Functional Dyspepsia

Interventions

BEHAVIORAL

No Results Yet

NCT07222800 | RECRUITING | PHASE3

800 participants

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-11
Completion:: 2030-03-29

Conditions

Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases
Colorectal Neoplasms

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT07222566 | RECRUITING | PHASE3

1410 participants

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-06
Completion:: 2029-02-27

Conditions

Advanced Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Carcinoma, Non-Small-Cell Lung
Carcinoma, Non-Small-Cell Lung (NSCLC)
Metastatic Non Small Cell Lung Cancer
Lung Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07221578 | ACTIVE_NOT_RECRUITING | PHASE3

500 participants

Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-22
Completion:: 2026-12-31

Conditions

Social Anxiety Disorder (SAD)

Interventions

DRUG

No Results Yet

NCT07221357 | RECRUITING | PHASE2/PHASE3

990 participants

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-31
Completion:: 2030-02-02

Conditions

Untreated, Unresectable, or Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT07218770 | TERMINATED | PHASE1/PHASE2

1 participants

A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-17
Completion:: 2026-07-21

Conditions

Active Noninfectious Uveitis Affecting the Posterior Segment

Interventions

DRUG

No Results Yet

NCT07217613 | COMPLETED | NA

100 participants

Prospective Evaluation of Silk Fibroin Incision Dressings in ACL Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-14
Completion:: 2026-05-01

Conditions

Anterior Cruciate Ligament Reconstruction

Interventions

DEVICE

No Results Yet