Clinical Trials

NCT06940232 | RECRUITING

330 participants

Validating a Blood Test for the Detection of Traumatic Brain Injury in Children

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2025-05-14

Completion:

2027-05-31

Conditions

• Pediatric Traumatic Brain Injury

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06939959 | COMPLETED | PHASE4

128 participants

Topical Insulin for Ocular Surface Interface in Dry Eye Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-04-14

Completion:

2026-04-19

Conditions

• Dry Eye
• Insulin Sensitivity

Interventions

• DRUG

Results Available

NCT06925737 | RECRUITING | PHASE3

1440 participants

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-05-13

Completion:

2028-06-26

Conditions

• Prostate Cancer
• Prostatic Neoplasms

Interventions

• DRUG

No Results Yet

NCT06914440 | RECRUITING | PHASE2

27 participants

Neoadjuvant SBRT Followed by Nab-Paclitaxel Combined With Toripalimab in HR+/HER2- Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-06-05

Completion:

2026-12-31

Conditions

• Breast Cancer

Interventions

• RADIATION
• DRUG
• PROCEDURE

No Results Yet

NCT06911073 | COMPLETED | NA

80 participants

A Study to Evaluate a Postbiotic in Supporting Weight Loss and Metabolic Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-05-02

Completion:

2026-03-01

Conditions

• Obesity and Overweight

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT06909253 | RECRUITING

50 participants

Ravulizumab Treatment Outcomes in Patients With Generalized Myasthenia Gravis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2025-05-15

Completion:

2029-12-31

Conditions

• Myasthenia Gravis, Generalized

Interventions

• DRUG

No Results Yet

NCT06907641 | COMPLETED | PHASE2

50 participants

Comparative Performance of 64Copper [64Cu]-SAR-bis-PSMA vs 68Ga PSMA-11 PET CT for the Detection of Prostate Cancer Recurrence in the Setting of Biochemical Failure Following Radical Prostatectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2024-11-21

Completion:

2025-09-03

Conditions

• Prostate Cancer (Post Prostatectomy)

Interventions

• DRUG

No Results Yet

NCT06904066 | RECRUITING | PHASE1

86 participants

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2026-08-19

Completion:

2029-04-30

Conditions

• Malignancy, Hematologic
• Neoplasms, Hematologic
• Neoplasms, Hematopoietic
• Blood Cancer
• Hematological Neoplasms
• Hematopoietic Malignancies
• Dysmyelopoietic Syndromes
• Hematopoetic Myelodysplasia
• Myeloid Leukemia, Acute
• Nonlymphoblastic Leukemia, Acute
• Leukemia, Lymphocytic, Acute

Interventions

• DRUG
• BIOLOGICAL
• DEVICE

No Results Yet

NCT06903208 | RECRUITING | NA

10 participants

RFA for Superficial Lipomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-04-02

Completion:

2027-07-31

Conditions

• Lipoma

Interventions

• DEVICE

No Results Yet

NCT06894654 | RECRUITING

500 participants

DERMATOMICS: Identifying Regulators of Skin Homeostasis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2024-12-10

Completion:

2027-11-01

Conditions

• Systemic Sclerosis (SSc)

Interventions

• PROCEDURE
• OTHER
• BEHAVIORAL

No Results Yet

NCT06893939 | RECRUITING | PHASE2/PHASE3

350 participants

Limited Versus Extended Trophic Feeding (LET-FEED) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-07-03

Completion:

2030-08-30

Conditions

• Sepsis
• Length of Stay
• Mortality
• Neurodevelopmental Delay

Interventions

• OTHER

No Results Yet

NCT06892288 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

50 participants

A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-07-09

Completion:

2026-08-05

Conditions

• Phosphomannomutase 2 Deficiency
• PMM2-CDG

Interventions

• DRUG

No Results Yet

NCT06890338 | RECRUITING | PHASE2

140 participants

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-11-21

Completion:

2030-02-28

Conditions

• Epithelial Ovarian Cancer
• Fallopian Tube Cancer
• Primary Peritoneal Cancer
• Neoadjuvant

Interventions

• DRUG

No Results Yet

NCT06880991 | RECRUITING

110 participants

Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2025-04-29

Completion:

2027-03-31

Conditions

• Neurofibromatosis Type 1
• Neurofibroma

Interventions

• OTHER

No Results Yet

NCT06879574 | ACTIVE_NOT_RECRUITING

133 participants

Identifying the Best Tools for Recording Diet in Free-living UK Adults (SODIAT-2 Study)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2025-08-25

Completion:

2026-08-31

Conditions

• Dietary Intake Assessment
• Food Intake Measurement

Interventions

• OTHER

No Results Yet

NCT06878274 | RECRUITING | PHASE2

118 participants

Post-operative Radiotherapy After Neodjuvant Chemo-immunotherapy and Surgery in Stage III NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2026-01-29

Completion:

2030-02-28

Conditions

• Non Small Cell Lung Cancer
• Stage III Lung Cancer

Interventions

• RADIATION

No Results Yet

NCT06876142 | SUSPENDED | PHASE1/PHASE2

54 participants

Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2026-08-19

Completion:

2033-01-01

Conditions

• Multiple Myeloma
• Relapsed and/or Refractory Multiple Myeloma (RRMM)

Interventions

• DRUG

No Results Yet

NCT06875310 | RECRUITING | PHASE3

630 participants

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-04-24

Completion:

2029-09-07

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT06870812 | RECRUITING | NA

600 participants

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-05-27

Completion:

2030-03-31

Conditions

• Stroke Hemorrhagic

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT06868914 | NOT_YET_RECRUITING | PHASE1

35 participants

Phase I Trial of High-Density Theta Burst Stimulation (hdTBS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2026-08-19

Completion:

2028-01-13

Conditions

• Healthy Volunteers

Interventions

• DEVICE

No Results Yet

NCT06866405 | RECRUITING | PHASE3

550 participants

A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-04-16

Completion:

2028-02-24

Conditions

• RSV Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT06864858 | COMPLETED | NA

53 participants

Clinical Evaluation of Two Cosmetic Contact Lenses

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-03-30

Completion:

2025-05-05

Conditions

• Visual Acuity

Interventions

• DEVICE

Results Available

NCT06860802 | ACTIVE_NOT_RECRUITING | PHASE1

46 participants

Precision Antibiotic Dosing for Appendectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-02-28

Completion:

2026-07-31

Conditions

• Appendicitis (Diagnosis)

Interventions

• DRUG

No Results Yet

NCT06860607 | RECRUITING | PHASE1

44 participants

Environment and Alcohol: A Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2026-08-19

Completion:

2027-03-01

Conditions

• Alcohol Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT06860594 | RECRUITING | PHASE1

30 participants

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-07-30

Completion:

2027-06-30

Conditions

• Astrocytoma, IDH-Mutant, Grade 2
• Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-Mutant
• Recurrent Adult Diffuse Midline Glioma, H3 K27-Mutant
• Recurrent Astrocytoma, IDH-Mutant
• Recurrent Astrocytoma, IDH-Mutant, Grade 3
• Recurrent Astrocytoma, IDH-Mutant, Grade 4
• Recurrent Glioblastoma, IDH-Wildtype

Interventions

• PROCEDURE
• RADIATION
• DRUG

No Results Yet

NCT06850636 | COMPLETED | NA

164 participants

Higher vs Lower Lumber Epidural Catheter Insertion During Labour: A Randomised Trial to Compare Efficacy.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-02-25

Completion:

2026-01-04

Conditions

• Labour Analgesia, Epidural Anaesthesia

Interventions

• PROCEDURE

No Results Yet

NCT06845202 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

105 participants

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-03-03

Completion:

2027-08-31

Conditions

• Obese or Overweight Healthy Volunteers
• Type 2 Diabetes Mellitus (T2DM)

Interventions

• DRUG

No Results Yet

NCT06844617 | COMPLETED | NA

30 participants

A Trial of Staff Time With Proned Patients in the ICU Using the 'BathMat'

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-06-05

Completion:

2026-06-04

Conditions

• Acute Respiratory Distress Syndrome (ARDS)
• Proning
• Intensive Care Medicine

Interventions

• DEVICE

No Results Yet

NCT06843785 | COMPLETED | NA

60 participants

Comparison of the Effectiveness of Two Different Squat Exercises in Healthy Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-03-01

Completion:

2025-05-01

Conditions

• Balance; Distorted
• Low Back Pain

Interventions

• OTHER

No Results Yet

NCT06843447 | RECRUITING | PHASE1/PHASE2

460 participants

A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-04-15

Completion:

2029-03-27

Conditions

• Ovarian Cancer Recurrent

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06841354 | RECRUITING | PHASE3

1000 participants

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-03-16

Completion:

2030-05-18

Conditions

• Triple Negative Breast Neoplasms

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06826768 | RECRUITING | PHASE1

60 participants

A Ph Ib Study of REGN5678 Plus Cemiplimab in Patients With mCRPC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-07-09

Completion:

2027-05-01

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT06824467 | RECRUITING | PHASE3

770 participants

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-04-09

Completion:

2029-04-27

Conditions

• Ovarian Cancer
• Fallopian Tube Cancer
• Primary Peritoneal Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06822738 | RECRUITING | PHASE3

130 participants

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-02-11

Completion:

2028-11-30

Conditions

• Primary Open Angle Glaucoma

Interventions

• DEVICE

No Results Yet

NCT06822543 | RECRUITING | PHASE2

46 participants

A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-09-12

Completion:

2028-06-30

Conditions

• Lung Cancer
• Non Small Cell Lung Cancer
• Brain Metastases

Interventions

• DRUG

No Results Yet

NCT06820463 | RECRUITING | PHASE2

390 participants

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-04-24

Completion:

2028-03-31

Conditions

• Metastatic Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT06813703 | COMPLETED | NA

60 participants

Analysis of the Analgesic Mechanism of TENS-WAA During Non-anesthetized Colonoscopy Using EEG-fNIRS System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-02-18

Completion:

2026-02-01

Conditions

• Colonoscopy
• Pain

Interventions

• DEVICE

No Results Yet

NCT06812871 | COMPLETED | PHASE2

46 participants

High-dose Furmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed Chemotherapy in Patients With EGFR-mutated Non-small Cell Lung Cancer and Meningeal Metastasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2024-01-01

Completion:

2026-03-30

Conditions

• Non-small Cell Lung Cancer Metastatic

Interventions

• DRUG

No Results Yet

NCT06812533 | RECRUITING | NA

350 participants

Alleviant ALLAY-HFrEF Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2025-03-10

Completion:

2028-12-31

Conditions

• Heart Failure

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06809907 | COMPLETED

1600 participants

Kintsugi Voice Device Pivotal Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2025-03-27

Completion:

2026-02-28

Conditions

• Depression
• Depression Moderate
• Depression Severe
• Depression Mild

Interventions

• DEVICE

No Results Yet