Clinical Trials

NCT03167437 | RECRUITING | PHASE1/PHASE2

35 participants

An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-10-30
Completion:: 2035-06-30

Conditions

Crohn's Disease

Interventions

DRUG

No Results Yet

NCT03153670 | RECRUITING | NA

250 participants

3T MRI in Patients With Deep Brain Stimulation (DBS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-06-01
Completion:: 2028-12-01

Conditions

Neuro-Degenerative Disease

Interventions

OTHER

No Results Yet

NCT03115931 | COMPLETED

4880 participants

The Effect of Perioperative Nutritional Assessment and Nutritional Support on Clinical Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-11-14
Completion:: 2025-06-30

Conditions

Nutrition Assessment
Nutritional Support
Clinical Outcomes
General Surgery

Interventions

OTHER

No Results Yet

NCT03092505 | COMPLETED

190 participants

Herpesviruses Reactivation In Hiv-Infected Women Initiating ART (HERA)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2018-06-15
Completion:: 2021-02-01

Conditions

Herpes Virus-Related Illnesses

No Results Yet

NCT03092492 | COMPLETED

26 participants

AMD Ryan Initiative Study (ARIS)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2018-02-12
Completion:: 2022-04-11

Conditions

Age-Related Macular Degeneration

No Results Yet

NCT03076554 | ACTIVE_NOT_RECRUITING | PHASE2

56 participants

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-04-19
Completion:: 2027-03-30

Conditions

Thymoma
Thymic Carcinoma

Interventions

DRUG

No Results Yet

NCT03065335 | RECRUITING | PHASE1

150 participants

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-05-25
Completion:: 2027-01-01

Conditions

Healthy Volunteer
Major Depressive Disorder
Depression

Interventions

DRUG
OTHER
DEVICE

No Results Yet

NCT03058835 | COMPLETED | PHASE4

162 participants

IN-US-276-1340: Pre-Exposure Prophylaxis to Prevent HIV Acquisition in US Women: A Demonstration Project

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-09-30
Completion:: 2024-09-30

Conditions

PrEP Adherence Monitoring

Interventions

DRUG

Results Available

NCT03030404 | COMPLETED

733 participants

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-01-27
Completion:: 2025-03-31

Conditions

Stomach Neoplasms
Stomach Cancer
Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS)
Hereditary Diffuse Gastric Cancer (HDGC)
Familial Diffuse Gastric Cancer

No Results Yet

NCT03020303 | COMPLETED | PHASE3

2538 participants

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-07-07
Completion:: 2025-03-14

Conditions

Endstage Renal Disease

Interventions

DRUG

No Results Yet

NCT03000244 | RECRUITING

2000 participants

Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell Transplantation, Cellular Therapy, or Gene Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-04-26
Completion:: 2050-08-12

Conditions

Cellular Immunotherapy, Adoptive
Genetic Therapy
Tissue Donors
Hematopoietic Stem Cell Transplantation

No Results Yet

NCT02989948 | RECRUITING | NA

80 participants

Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2020-04-22
Completion:: 2027-12-31

Conditions

Aortic Aneurysm, Thoracoabdominal

Interventions

DEVICE

No Results Yet

NCT02978625 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-09-27
Completion:: 2027-09-01

Conditions

Anaplastic Large Cell Lymphoma, ALK-Negative
Anaplastic Large Cell Lymphoma, ALK-Positive
Apocrine Carcinoma
Carcinoma Arising From Cylindroma
Carcinoma Arising From Spiradenoma
Digital Papillary Adenocarcinoma
Endocrine Mucin-Producing Sweat Gland Carcinoma
Extramammary Paget Disease
Extraocular Sebaceous Carcinoma
Hidradenocarcinoma
Malignant Sweat Gland Neoplasm
Merkel Cell Carcinoma
Microcystic Adnexal Carcinoma
NK-Cell Lymphoma, Unclassifiable
Papillary Adenocarcinoma
Porocarcinoma
Primary Cutaneous Mucinous Carcinoma
Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
Recurrent T-Cell Non-Hodgkin Lymphoma
Refractory Anaplastic Large Cell Lymphoma
Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
Refractory Merkel Cell Carcinoma
Refractory Mycosis Fungoides
Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
Refractory Skin Squamous Cell Carcinoma
Refractory T-Cell Non-Hodgkin Lymphoma
Sezary Syndrome
Signet Ring Cell Adenocarcinoma
Skin Adenoid Cystic Carcinoma
Skin Adnexal Carcinoma
Skin Basal Cell Carcinoma
Skin Basosquamous Cell Carcinoma
Skin Keratoacanthoma
Skin Squamous Cell Carcinoma
Squamoid Eccrine Ductal Carcinoma
Squamous Cell Carcinoma of Unknown Primary
Sweat Gland Carcinoma
Trichilemmal Carcinoma
Vulvar Squamous Cell Carcinoma

Interventions

PROCEDURE
OTHER
BIOLOGICAL

No Results Yet

NCT02971501 | ACTIVE_NOT_RECRUITING | PHASE2

5 participants

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2018-06-27
Completion:: 2025-02-18

Conditions

Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Brain
Stage IV Lung Cancer AJCC v8

Interventions

BIOLOGICAL
PROCEDURE
DRUG

Results Available

NCT02941263 | COMPLETED

20 participants

Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-03-08
Completion:: 2024-05-22

Conditions

Age-Related Macular Degeneration

No Results Yet

NCT02911103 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

5 participants

Deep Brain Stimulation Surgery for Focal Hand Dystonia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2018-01-17
Completion:: 2029-02-02

Conditions

Dystonia
Focal Dystonia
Musician's Dystonia

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT02858323 | COMPLETED

68 participants

Complement (C1q) Binding to HLA Antibodies in a Solid-phase Immunoassay and Clinical Effect on Platelet Transfusion

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-07-27
Completion:: 2017-06-20

Conditions

Thrombocytopenia
Platelet Transfusion Refractoriness

No Results Yet

NCT02830724 | RECRUITING | PHASE1/PHASE2

124 participants

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-04-06
Completion:: 2029-01-01

Conditions

Pancreatic Cancer
Renal Cell Cancer
Breast Cancer
Melanoma
Ovarian Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT02821806 | RECRUITING

500 participants

Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy People for the Expansion of T Cells for Adoptive Cell Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-08-08
Completion:: 2030-03-01

Conditions

Healthy Volunteer

No Results Yet

NCT02821780 | COMPLETED

20 participants

CADASIL Disease Discovery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-10-18
Completion:: 2022-05-03

Conditions

Germline Mutation in the NOTCH 3 Gene
Cardiovascular Disease
Arterial Stiffness
Pathogenesis of CADASIL
Clinical Phenotype of CADASIL

No Results Yet

NCT02821741 | RECRUITING | NA

76 participants

Effects of External Ear Stimulation on Pain Perception and Mood

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-10-18
Completion:: 2027-03-30

Conditions

Pain in Healthy Participants

Interventions

DEVICE

No Results Yet

NCT02782663 | COMPLETED | PHASE2

107 participants

A Study to Evaluate the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Participants With Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-05-18
Completion:: 2025-07-18

Conditions

Crohn's Disease (CD)

Interventions

DRUG

Results Available

NCT02769975 | RECRUITING

15000 participants

Evaluation of Children With Endocrine and Metabolic-Related Conditions

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-07-12
Completion:: 2030-12-31

Conditions

Adrenal Insufficiency
Growth Disorder
Endocrine Diseases
Metabolic Disease
Bone Diseases, Metabolic

No Results Yet

NCT02769962 | TERMINATED | PHASE1/PHASE2

45 participants

Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-05-09
Completion:: 2023-04-19

Conditions

Urothelial Carcinoma
Urothelial Cancer
Lung Neoplasms
Small Cell Lung Cancer
Prostate Cancer

Interventions

DRUG
DIAGNOSTIC_TEST
PROCEDURE

Results Available

NCT02759744 | ENROLLING_BY_INVITATION | NA

30 participants

Fusion Guided Focal Laser Ablation of Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-10-13
Completion:: 2027-01-21

Conditions

Prostate Cancer
Prostate Neoplasms

Interventions

DEVICE

No Results Yet

NCT02741440 | ACTIVE_NOT_RECRUITING

22 participants

Natural History of Spinocerebellar Ataxia Type 7 (SCA7)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-07-11
Completion:: 2028-12-31

Conditions

Spinocerebellar Ataxia

No Results Yet

NCT02732184 | COMPLETED | PHASE1

21 participants

A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-08-15
Completion:: 2017-11-01

Conditions

Acute Myeloid Leukemia
Myelodysplastic Syndrome

Interventions

DRUG

No Results Yet

NCT02707029 | RECRUITING

10000 participants

Clinical and Scientific Assessment of Pain and Painful Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-07-22
Completion:: 2027-02-09

Conditions

Normal Physiology
Pain

No Results Yet

NCT02692846 | COMPLETED

43 participants

WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2017-03-03
Completion:: 2017-12-15

Conditions

Williams Syndrome
Cardiovascular Disease
Multisystem Developmental Disorder
Elastin Gene Deletion
Hypertension

No Results Yet

NCT02689466 | COMPLETED

31 participants

Cholinergic Receptor Imaging in Dystonia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-12-16
Completion:: 2021-11-26

Conditions

Cervical Dystonia
Dystonia
Movement Disorder
Focal Dystonia

Interventions

DRUG

No Results Yet

NCT02669225 | COMPLETED | EARLY_PHASE1

22 participants

Brain Amyloid- Retention During Wakefulness and Following Emergence From Sleep in Healthy People

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-05-02
Completion:: 2017-01-24

Conditions

Normal Physiology

Interventions

OTHER

No Results Yet

NCT02659930 | ACTIVE_NOT_RECRUITING | PHASE1

62 participants

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-01-13
Completion:: 2028-01-01

Conditions

Kaposi Sarcoma

Interventions

DRUG

No Results Yet

NCT02639299 | RECRUITING

1500 participants

Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-12-08
Completion:: 2030-09-30

Conditions

Malaria

No Results Yet

NCT02629107 | RECRUITING

2378 participants

Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-01-14
Completion:: 2044-12-31

Conditions

Normal Physiology

No Results Yet

NCT02624596 | COMPLETED | PHASE2

120 participants

Understanding How Ketamine Brings About Rapid Improvement in OCD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-08-16
Completion:: 2021-06-20

Conditions

Obsessive-Compulsive Disorder

Interventions

DRUG

No Results Yet

NCT02595957 | RECRUITING

5000 participants

Genomic Services Research Program

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-13
Start Date:: 2014-09-16
Completion:: 2028-12-31

Conditions

Colon Cancer
Breast Cancer

No Results Yet

NCT02577926 | ACTIVE_NOT_RECRUITING | PHASE2

207 participants

The Ruxo-BEAT Trial in Patients With High-risk Polycythemia Vera or High-risk Essential Thrombocythemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2015-10-31
Completion:: 2027-12-31

Conditions

Polycythemia Vera (PV)
Essential Thrombocythemia (ET)

Interventions

DRUG

No Results Yet

NCT02553733 | COMPLETED | PHASE2

11 participants

Effect of Beetroot Juice on Coronary Blood Flow and Walking Performance in PAD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2015-12-31
Completion:: 2020-02-29

Conditions

Peripheral Arterial Disease

Interventions

DRUG

Results Available

NCT02515877 | COMPLETED | PHASE1

15 participants

Modulation of the Expression of Papillomavirus (HPV) Oncoproteins to Major the Radiosensitivity: Trial Combining an Antiviral Agent VISTIDE and Radiochemotherapy in Cervical Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2008-01-31
Completion:: 2013-04-30

Conditions

Cervical Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT02407405 | ACTIVE_NOT_RECRUITING | PHASE2

36 participants

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-13
Start Date:: 2016-01-07
Completion:: 2028-01-01

Conditions

Neurofibromatosis 1 (NF1)
Plexiform Neurofibromas (PN)

Interventions

DRUG

No Results Yet