Clinical Trials

NCT03782207 | COMPLETED

2756 participants

A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2019-02-07

Completion:

2026-07-31

Conditions

• Urothelial Carcinoma
• Non-Small Cell Lung Cancer
• Small Cell Lung Cancer
• Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT03737955 | RECRUITING | PHASE2

36 participants

Fractionated Gemtuzumab Ozogamicin in Treating Measurable Residual Disease in Patients With Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-11-30

Completion:

2026-12-31

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG
• OTHER
• PROCEDURE

No Results Yet

NCT03653338 | RECRUITING | PHASE1/PHASE2

5 participants

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-08-02

Completion:

2028-08-01

Conditions

• Sickle Cell Anemia
• Beta-thalassemia Major
• Diamond-blackfan Anemia

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03649555 | COMPLETED | PHASE1

5 participants

Reliability of [18F]-FTC-146 Brain Uptake in Healthy Controls

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-02-01

Completion:

2020-03-03

Conditions

• Healthy Controls

Interventions

• DRUG

No Results Yet

NCT03624660 | ACTIVE_NOT_RECRUITING | PHASE2

100 participants

Dose-Escalated Proton Radiation Therapy for High-Risk Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-09-24

Completion:

2029-09-30

Conditions

• Adenocarcinoma of the Prostate

Interventions

• RADIATION

No Results Yet

NCT03538457 | RECRUITING

12 participants

Bariatric Surgery and Pharmacokinetics of Paracetamol

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2016-11-02

Completion:

2026-10-31

Conditions

• Obesity, Morbid

Interventions

• DRUG

No Results Yet

NCT03535376 | RECRUITING

12 participants

Bariatric Surgery and Pharmacokinetics of Valsartan

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2016-11-02

Completion:

2026-10-31

Conditions

• Obesity, Morbid

Interventions

• DRUG

No Results Yet

NCT03519906 | RECRUITING

12 participants

Bariatric Surgery and Pharmacokinetics of Metoprolol

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2016-11-02

Completion:

2026-10-31

Conditions

• Obesity, Morbid

Interventions

• DRUG

No Results Yet

NCT03519893 | RECRUITING

12 participants

Bariatric Surgery and Pharmacokinetics of Losartan

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2016-11-02

Completion:

2026-10-31

Conditions

• Obesity, Morbid

Interventions

• DRUG

No Results Yet

NCT03511534 | ACTIVE_NOT_RECRUITING | NA

200 participants

Open/Aftercare Treatment for Participants Diagnosed With Obsessive Compulsive Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2017-06-23

Completion:

2027-06-30

Conditions

• OCD

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT03497143 | RECRUITING

12 participants

Bariatric Surgery and Pharmacokinetics of Lamotrigine

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2016-11-02

Completion:

2026-10-31

Conditions

• Obesity, Morbid

Interventions

• DRUG

No Results Yet

NCT03487224 | ACTIVE_NOT_RECRUITING

25 participants

Neural Mechanisms of Decision Making in Hoarding Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2018-07-08

Completion:

2027-05-30

Conditions

• Hoarding Disorder

Interventions

• DEVICE

No Results Yet

NCT03484130 | ACTIVE_NOT_RECRUITING

100 participants

Prospective Phenotyping of Autonomous Aldosterone Secretion

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2018-06-15

Completion:

2029-07-01

Conditions

• Aldosterone Disorder
• Adrenal Gland Disease
• Blood Pressure

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT03409432 | COMPLETED | PHASE2

26 participants

Brentuximab Vedotin and Lenalidomide in Treating Patients With Stage IB-IVB Relapsed or Refractory T-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-03-16

Completion:

2025-07-16

Conditions

• Lymphomatoid Papulosis
• Primary Cutaneous Anaplastic Large Cell Lymphoma
• Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
• Recurrent T-Cell Non-Hodgkin Lymphoma
• Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
• Stage I Cutaneous T-Cell Non-Hodgkin Lymphoma
• Stage II Cutaneous T-Cell Non-Hodgkin Lymphoma
• Stage III Cutaneous T-Cell Non-Hodgkin Lymphoma
• Stage IV Cutaneous T-Cell Non-Hodgkin Lymphoma

Interventions

• DRUG
• OTHER

Results Available

NCT03389802 | COMPLETED | PHASE1

32 participants

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-03-01

Completion:

2023-09-30

Conditions

• Glioblastoma Multiforme
• High-grade Astrocytoma Not Otherwise Specified (NOS)
• CNS Primary Tumor, Not Otherwise Specified (NOS)
• Ependymoma, Not Otherwise Specified (NOS)
• Diffuse Intrinsic Pontine Gliomas (DIPG)
• Medulloblastoma

Interventions

• BIOLOGICAL

Results Available

NCT03332797 | ACTIVE_NOT_RECRUITING | PHASE1

181 participants

A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2017-11-24

Completion:

2027-07-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT03326804 | ACTIVE_NOT_RECRUITING

250 participants

H1 Hip Resurfacing Arthroplasty

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2017-09-26

Completion:

2032-03-17

Conditions

• Hip Osteoarthritis
• Hip Necrosis
• Hip Dysplasia

Interventions

• DEVICE

No Results Yet

NCT03238690 | RECRUITING | NA

100 participants

LVAD Conditioning for Cardiac Recovery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2017-06-23

Completion:

2028-06-30

Conditions

• Heart Failure

Interventions

• DEVICE

No Results Yet

NCT03182075 | COMPLETED | NA

5 participants

Computerized Training for Individuals Diagnosed With Obsessive-Compulsive and Related Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-04-30

Completion:

2018-11-12

Conditions

• Obsessive Compulsive Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT03153670 | RECRUITING | NA

250 participants

3T MRI in Patients With Deep Brain Stimulation (DBS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2017-06-01

Completion:

2028-12-01

Conditions

• Neuro-Degenerative Disease

Interventions

• OTHER

No Results Yet

NCT03115931 | COMPLETED

4880 participants

The Effect of Perioperative Nutritional Assessment and Nutritional Support on Clinical Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2017-11-14

Completion:

2025-06-30

Conditions

• Nutrition Assessment
• Nutritional Support
• Clinical Outcomes
• General Surgery

Interventions

• OTHER

No Results Yet

NCT03058835 | COMPLETED | PHASE4

162 participants

IN-US-276-1340: Pre-Exposure Prophylaxis to Prevent HIV Acquisition in US Women: A Demonstration Project

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2016-09-30

Completion:

2024-09-30

Conditions

• PrEP Adherence Monitoring

Interventions

• DRUG

Results Available

NCT03020303 | COMPLETED | PHASE3

2538 participants

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2017-07-07

Completion:

2025-03-14

Conditions

• Endstage Renal Disease

Interventions

• DRUG

No Results Yet

NCT02989948 | RECRUITING | NA

80 participants

Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-04-22

Completion:

2027-12-31

Conditions

• Aortic Aneurysm, Thoracoabdominal

Interventions

• DEVICE

No Results Yet

NCT02978625 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2017-09-27

Completion:

2027-09-01

Conditions

• Anaplastic Large Cell Lymphoma, ALK-Negative
• Anaplastic Large Cell Lymphoma, ALK-Positive
• Apocrine Carcinoma
• Carcinoma Arising From Cylindroma
• Carcinoma Arising From Spiradenoma
• Digital Papillary Adenocarcinoma
• Endocrine Mucin-Producing Sweat Gland Carcinoma
• Extramammary Paget Disease
• Extraocular Sebaceous Carcinoma
• Hidradenocarcinoma
• Malignant Sweat Gland Neoplasm
• Merkel Cell Carcinoma
• Microcystic Adnexal Carcinoma
• NK-Cell Lymphoma, Unclassifiable
• Papillary Adenocarcinoma
• Porocarcinoma
• Primary Cutaneous Mucinous Carcinoma
• Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
• Recurrent T-Cell Non-Hodgkin Lymphoma
• Refractory Anaplastic Large Cell Lymphoma
• Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
• Refractory Merkel Cell Carcinoma
• Refractory Mycosis Fungoides
• Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
• Refractory Skin Squamous Cell Carcinoma
• Refractory T-Cell Non-Hodgkin Lymphoma
• Sezary Syndrome
• Signet Ring Cell Adenocarcinoma
• Skin Adenoid Cystic Carcinoma
• Skin Adnexal Carcinoma
• Skin Basal Cell Carcinoma
• Skin Basosquamous Cell Carcinoma
• Skin Keratoacanthoma
• Skin Squamous Cell Carcinoma
• Squamoid Eccrine Ductal Carcinoma
• Squamous Cell Carcinoma of Unknown Primary
• Sweat Gland Carcinoma
• Trichilemmal Carcinoma
• Vulvar Squamous Cell Carcinoma

Interventions

• PROCEDURE
• OTHER
• BIOLOGICAL

No Results Yet

NCT02971501 | ACTIVE_NOT_RECRUITING | PHASE2

5 participants

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-06-27

Completion:

2025-02-18

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Metastatic Malignant Neoplasm in the Brain
• Stage IV Lung Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

Results Available

NCT02830724 | RECRUITING | PHASE1/PHASE2

124 participants

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2017-04-06

Completion:

2029-01-01

Conditions

• Pancreatic Cancer
• Renal Cell Cancer
• Breast Cancer
• Melanoma
• Ovarian Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT02782663 | COMPLETED | PHASE2

107 participants

A Study to Evaluate the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Participants With Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2016-05-18

Completion:

2025-07-18

Conditions

• Crohn's Disease (CD)

Interventions

• DRUG

Results Available

NCT02769975 | RECRUITING

15000 participants

Evaluation of Children With Endocrine and Metabolic-Related Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2016-07-12

Completion:

2030-12-31

Conditions

• Adrenal Insufficiency
• Growth Disorder
• Endocrine Diseases
• Metabolic Disease
• Bone Diseases, Metabolic

No Results Yet

NCT02769962 | TERMINATED | PHASE1/PHASE2

45 participants

Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2016-05-09

Completion:

2023-04-19

Conditions

• Urothelial Carcinoma
• Urothelial Cancer
• Lung Neoplasms
• Small Cell Lung Cancer
• Prostate Cancer

Interventions

• DRUG
• DIAGNOSTIC_TEST
• PROCEDURE

Results Available

NCT02759744 | ENROLLING_BY_INVITATION | NA

30 participants

Fusion Guided Focal Laser Ablation of Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2017-10-13

Completion:

2027-01-21

Conditions

• Prostate Cancer
• Prostate Neoplasms

Interventions

• DEVICE

No Results Yet

NCT02732184 | COMPLETED | PHASE1

21 participants

A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2016-08-15

Completion:

2017-11-01

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndrome

Interventions

• DRUG

No Results Yet

NCT02692846 | COMPLETED

43 participants

WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2017-03-03

Completion:

2017-12-15

Conditions

• Williams Syndrome
• Cardiovascular Disease
• Multisystem Developmental Disorder
• Elastin Gene Deletion
• Hypertension

No Results Yet

NCT02624596 | COMPLETED | PHASE2

120 participants

Understanding How Ketamine Brings About Rapid Improvement in OCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2016-08-16

Completion:

2021-06-20

Conditions

• Obsessive-Compulsive Disorder

Interventions

• DRUG

No Results Yet

NCT02577926 | ACTIVE_NOT_RECRUITING | PHASE2

207 participants

The Ruxo-BEAT Trial in Patients With High-risk Polycythemia Vera or High-risk Essential Thrombocythemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2015-10-31

Completion:

2027-12-31

Conditions

• Polycythemia Vera (PV)
• Essential Thrombocythemia (ET)

Interventions

• DRUG

No Results Yet

NCT02553733 | COMPLETED | PHASE2

11 participants

Effect of Beetroot Juice on Coronary Blood Flow and Walking Performance in PAD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2015-12-31

Completion:

2020-02-29

Conditions

• Peripheral Arterial Disease

Interventions

• DRUG

Results Available

NCT02515877 | COMPLETED | PHASE1

15 participants

Modulation of the Expression of Papillomavirus (HPV) Oncoproteins to Major the Radiosensitivity: Trial Combining an Antiviral Agent VISTIDE and Radiochemotherapy in Cervical Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2008-01-31

Completion:

2013-04-30

Conditions

• Cervical Cancer

Interventions

• RADIATION
• DRUG

No Results Yet

NCT02407405 | ACTIVE_NOT_RECRUITING | PHASE2

36 participants

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2016-01-07

Completion:

2028-01-01

Conditions

• Neurofibromatosis 1 (NF1)
• Plexiform Neurofibromas (PN)

Interventions

• DRUG

No Results Yet

NCT02371460 | TERMINATED | PHASE3

461 participants

Maternal Omega-3 Supplementation to Reduce Bronchopulmonary Dysplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2015-06-23

Completion:

2019-04-25

Conditions

• Bronchopulmonary Dysplasia
• Child Development
• Neonatal and Perinatal Conditions

Interventions

• DIETARY_SUPPLEMENT
• COMBINATION_PRODUCT

No Results Yet

NCT02246374 | COMPLETED | NA

7 participants

ExAblate Transcranial MRgFUS of the Subthalamic Nucleus for Treatment of Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2014-09-30

Completion:

2021-05-31

Conditions

• Parkinson's Disease

Interventions

• DEVICE

Results Available