Clinical Trials

NCT06840886 | RECRUITING | PHASE1

272 participants

A Study of PHST001 in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-03-31

Completion:

2029-04-30

Conditions

• Advanced Solid Tumors
• Ovarian Cancer
• Endometrial Cancer
• Cholangiocarcinoma
• CNS Tumor

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06838676 | RECRUITING | PHASE2

60 participants

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-07-10

Completion:

2028-07-31

Conditions

• Diffuse Intrinsic Pontine Gliomas (DIPG)
• Progressive DIPG
• Refractory DIPG
• Recurrent DIPG
• H3K27-altered High Grade Glioma

Interventions

• DRUG

No Results Yet

NCT06837532 | COMPLETED | NA

90 participants

Ultrasound Guided Versus Surgical Rectus Sheath Block Versus Local Anesthesia Infiltration for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-02-20

Completion:

2025-08-01

Conditions

• Ultrasound
• Surgical
• Rectus Sheath Block
• Local Anesthesia Infiltration
• Postoperative Analgesia
• Total Abdominal Hysterectomy

Interventions

• DRUG

No Results Yet

NCT06837506 | COMPLETED | NA

80 participants

Ultrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal Hysterectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-02-20

Completion:

2025-12-01

Conditions

• Ultrasound
• Rectus Sheath Block
• Intrathecal Morphine
• Postoperative Analgesia
• Total Abdominal Hysterectomy

Interventions

• DRUG

No Results Yet

NCT06833541 | COMPLETED

556 participants

Research on Gut Microbiota and Metabolomics in Diabetic Kidney Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2022-04-18

Completion:

2025-12-01

Conditions

• Diabetic Nephropathy Type 2
• Type 2 Diabetes Mellitus (T2DM)
• Chronic Kidney Disease

No Results Yet

NCT06827054 | NOT_YET_RECRUITING | PHASE2

20 participants

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-09-15

Completion:

2027-05-05

Conditions

• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

• PROCEDURE
• OTHER
• DRUG
• BEHAVIORAL

No Results Yet

NCT06824493 | RECRUITING

150 participants

Orthodontic Treatment on Oral Microbiota and Salivary Proteins

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2025-07-01

Completion:

2027-03-01

Conditions

• Orthodontics
• White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
• Caries, Dental

Interventions

• OTHER

No Results Yet

NCT06824441 | ACTIVE_NOT_RECRUITING | NA

85 participants

Feasibility Usability & Acceptability Study: Symptom Reporting by Children Adolescents & Young Adults w/Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-08-18

Completion:

2026-10-31

Conditions

• Adolescent Behavior
• Pediatric Cancer
• Oncology

Interventions

• BEHAVIORAL

No Results Yet

NCT06824025 | RECRUITING | EARLY_PHASE1

111 participants

Comparison of Nebulized Neostigmine/Atropine Versus Lignocaine in Treating Acute Post-dural Puncture Headache Following Subarachnoid Block in Parturient Undergoing Elective Cesarean Section. A Randomized, Clinical Trial.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-02-20

Completion:

2027-01-01

Conditions

• Post-Dural Puncture Headache

Interventions

• DRUG

No Results Yet

NCT06822790 | RECRUITING | PHASE3

869 participants

Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-04-09

Completion:

2028-07-31

Conditions

• Hypertriglyceridemia

Interventions

• DRUG

No Results Yet

NCT06819852 | NOT_YET_RECRUITING | NA

200 participants

Acute Hospital Care at Home for People Living With Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-08-17

Completion:

2029-04-01

Conditions

• Emergency Department Visit
• Home Care Services
• Dementia

Interventions

• OTHER

No Results Yet

NCT06811909 | ACTIVE_NOT_RECRUITING | NA

71 participants

Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-02-14

Completion:

2026-08-31

Conditions

• Non-infected Venous Leg Ulcer
• Venous Leg Ulcer
• Venous Insufficiency
• Venous Stasis
• Venous Reflux

Interventions

• OTHER

No Results Yet

NCT06803316 | COMPLETED

658 participants

Optimizing Care Delivery to Support Reengagement in PLWH Returning to HIV Care After Treatment Lapses in Zambia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2022-08-10

Completion:

2025-07-31

Conditions

• HIV Antiretroviral Therapy (ART) Adherence

No Results Yet

NCT06801899 | RECRUITING | NA

170 participants

ToPanc Trial: Survival After Total Versus Partial Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head, Distal Cholangiocarcinoma, and Ampullary Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-06-01

Completion:

2030-10-31

Conditions

• Pancreatic Cancer

Interventions

• PROCEDURE

No Results Yet

NCT06801834 | RECRUITING | PHASE3

695 participants

Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-04-04

Completion:

2029-10-31

Conditions

• Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Interventions

• DRUG

No Results Yet

NCT06801119 | RECRUITING | PHASE1

30 participants

Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs）

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-03-16

Completion:

2027-12-31

Conditions

• Systemic Lupus Erythematosus
• Scleroderma
• Rheumatoid Arthritis

Interventions

• DRUG

No Results Yet

NCT06801041 | RECRUITING | PHASE2

20 participants

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-05-23

Completion:

2027-03-31

Conditions

• Depression
• Anxiety
• Cancer

Interventions

• DRUG

No Results Yet

NCT06797336 | RECRUITING | PHASE1

240 participants

A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-12-19

Completion:

2026-12-15

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06792825 | RECRUITING | PHASE2

65 participants

HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-08-07

Completion:

2029-07-08

Conditions

• Follicular Lymphoma
• Marginal Zone Lymphoma

Interventions

• DRUG

No Results Yet

NCT06789913 | RECRUITING | PHASE2

277 participants

A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-06-13

Completion:

2031-07-31

Conditions

• PIK3CA-Related Overgrowth Spectrum (PROS)
• Lymphatic Malformations
• Vascular Malformations
• PIK3CA Mutation
• CLOVES Syndrome
• Klippel Trenaunay Syndrome
• Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)
• Vascular Anomalies

Interventions

• DRUG

No Results Yet

NCT06789406 | RECRUITING | NA

55 participants

PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-09-18

Completion:

2027-01-31

Conditions

• Urinary Urge Incontinence (UUI)
• Urinary Frequency (UF)
• Overactive Bladder (OAB)

Interventions

• DEVICE

No Results Yet

NCT06787612 | RECRUITING | PHASE2

297 participants

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-05-28

Completion:

2028-06-30

Conditions

• Ovarian Cancer
• Fallopian Tube Cancer
• Primary Peritoneal Cancer

Interventions

• DRUG

No Results Yet

NCT06777433 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-12-13

Completion:

2026-04-23

Conditions

• Brain Metastases From Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06771739 | NOT_YET_RECRUITING | NA

20 participants

A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-09-01

Completion:

2026-12-01

Conditions

• Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT06770530 | RECRUITING | PHASE4

420 participants

Introduction of Mycotic Prophylaxis At Cystectomy Trial.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-06-24

Completion:

2027-06-30

Conditions

• Cystectomy

Interventions

• DRUG

No Results Yet

NCT06766851 | COMPLETED | NA

30 participants

Evaluation of the Effectiveness of Arthrocentesis Using Catheter in the Treatment of Temporamandibular Joint Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-01-13

Completion:

2026-03-15

Conditions

• TMJ Disc Disorder
• Treatment
• Arthrocentesis

Interventions

• OTHER

No Results Yet

NCT06759649 | RECRUITING | PHASE1

200 participants

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-01-07

Completion:

2027-11-22

Conditions

• Neoplasm
• Cancer, Malignant Tumors

Interventions

• DRUG

No Results Yet

NCT06757075 | RECRUITING | PHASE4

75 participants

Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-04-16

Completion:

2027-03-31

Conditions

• Pain, Postoperative

Interventions

• DRUG

No Results Yet

NCT06748053 | ACTIVE_NOT_RECRUITING | PHASE2

307 participants

A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-02-10

Completion:

2026-07-14

Conditions

• Asthma

Interventions

• DRUG

No Results Yet

NCT06747221 | NOT_YET_RECRUITING | NA

184 participants

Implementation Science to Enhance HIV Testing Services During Emergency Care in Kenya

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2027-02-01

Completion:

2028-06-30

Conditions

• HIV

Interventions

• OTHER

No Results Yet

NCT06744517 | COMPLETED | NA

36 participants

Influence of Menstrual Cycle Phase on Adaptations to Sprint Interval Training

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-01-01

Completion:

2026-07-30

Conditions

• Healthy

Interventions

• OTHER

No Results Yet

NCT06725550 | RECRUITING | NA

120 participants

Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-07-01

Completion:

2030-06-28

Conditions

• Sickle Cell Disease
• Pain
• Acupuncture
• Quantitative Sensory Testing
• Magnetic Resonance Imaging
• Circulating Biomarkers
• Electroencephalography
• Functional Near-infrared Spectroscopy

Interventions

• DEVICE

No Results Yet

NCT06719141 | ACTIVE_NOT_RECRUITING | PHASE3

367 participants

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-11-11

Completion:

2026-10-31

Conditions

• Developmental and Epileptic Encephalopathy

Interventions

• DRUG

No Results Yet

NCT06717308 | RECRUITING | NA

300 participants

Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-02-10

Completion:

2027-02-28

Conditions

• Frequency and Type of Medical Adhesive-Related Skin Injury
• NPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate)
• Clinician Acceptability of New NPWT Drape
• Patient Drop-out Rate From Prescribed NPWT Treatment
• Pain Assessment During Medical Adhesive Drape Removal

Interventions

• DEVICE

No Results Yet

NCT06710483 | RECRUITING | NA

50 participants

A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-08-20

Completion:

2026-10-31

Conditions

• Intellectual Disability, Variable

Interventions

• BEHAVIORAL

No Results Yet

NCT06706427 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

Safety and Efficacy Study of NGGT001 in Bietti Crystalline Corneoretinal Dystrophy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-03-21

Completion:

2025-11-30

Conditions

• Bietti Crystalline Corneoretinal Dystrophy

Interventions

• BIOLOGICAL

No Results Yet

NCT06706232 | RECRUITING | PHASE2

10 participants

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-07-07

Completion:

2027-08-31

Conditions

• Bipolar II Disorder
• Depression, Bipolar
• Suicidality

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT06693531 | ACTIVE_NOT_RECRUITING

368 participants

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2024-11-22

Completion:

2030-05-22

Conditions

• Eosinophilic Esophagitis (EoE)

Interventions

• DRUG

No Results Yet

NCT06691269 | RECRUITING | NA

200 participants

Photobiomodulation and Tooth Analgesia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-07-07

Completion:

2027-06-30

Conditions

• Dental Anaesthesia
• Dental Pain
• Dental Analgesia

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06688435 | RECRUITING | PHASE1

60 participants

A Study to Evaluate the Safety and Preliminary Efficacy of SYS6020 CAR T-cells in Patients With Refractory Generalized Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-03-04

Completion:

2028-12-01

Conditions

• Myasthenia Gravis

Interventions

• BIOLOGICAL

No Results Yet