Clinical Trials Updated in 2026

NCT06543576 | RECRUITING | PHASE1/PHASE2

35 participants

External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-07-29
Completion:: 2031-01-31

Conditions

Cervical Adenocarcinoma
Cervical Adenosquamous Carcinoma
Cervical Squamous Cell Carcinoma
Stage IVB Cervical Cancer American Joint Committee on Cancer (AJCC) v8

Interventions

BIOLOGICAL
PROCEDURE
RADIATION
DRUG
OTHER

No Results Yet

NCT06542120 | RECRUITING

30000 participants

Research on Body Voice AI Recognition System for Children's Health Management

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-01
Completion:: 2026-12-31

Conditions

Congenital Heart Disease
Bronchopneumonia
Abdominal Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06538285 | COMPLETED | PHASE2

17 participants

Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-03-04
Completion:: 2026-05-05

Conditions

Methamphetamine Use Disorder

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT06531083 | RECRUITING | NA

30 participants

Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-03-01
Completion:: 2026-09-30

Conditions

Head and Neck Cancer
Trismus

Interventions

BEHAVIORAL

No Results Yet

NCT06529029 | RECRUITING | PHASE2/PHASE3

30 participants

Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-07-03
Completion:: 2026-10-01

Conditions

Suicidal Ideation
Major Depressive Disorder
Schizo Affective Disorder
Bipolar Disorder

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06526819 | RECRUITING | PHASE1/PHASE2

120 participants

SMP-3124LP in Adults With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-08-14
Completion:: 2028-12-31

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06525766 | RECRUITING | PHASE2

35 participants

Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-10-01
Completion:: 2030-10-15

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Estrogen-receptor-positive Breast Cancer
Metastatic HER2-Negative Breast Carcinoma
Metastatic Breast Cancer

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT06517758 | ACTIVE_NOT_RECRUITING | PHASE3

146 participants

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-07-31
Completion:: 2027-04-30

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG
OTHER

No Results Yet

NCT06512597 | RECRUITING | NA

170 participants

Behavioral Therapy for Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-01
Completion:: 2027-07-30

Conditions

Crohn's Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06511141 | RECRUITING | NA

150 participants

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-22
Completion:: 2027-12-31

Conditions

Overactive Bladder
Urinary Urgency Incontinence
Benign Prostatic Hyperplasia
Prostate Cancer
Prostatectomy
Urinary Frequency

Interventions

DEVICE

No Results Yet

NCT06489769 | SUSPENDED

200 participants

Opioid Misuse in Patients With Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-15
Completion:: 2026-12-31

Conditions

Cancer
Opioid Use
Opioid Misuse
Pain
Cancer Pain

No Results Yet

NCT06468137 | ACTIVE_NOT_RECRUITING | NA

100 participants

Follow Up of an Online Hearing Support for First-time Hearing Aid Users

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-07-01
Completion:: 2026-12-31

Conditions

Hearing Loss
Hearing Impairment
Hearing Disorders

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06464705 | RECRUITING | NA

60 participants

To Investigate the Effect of PEMF for Pateitns After Anterior Cruciate Ligament Reconstruction With Hamstring Autograft

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-13
Completion:: 2027-03-31

Conditions

Anterior Cruciate Ligament Reconstruction
Hamstring Muscle

Interventions

DEVICE

No Results Yet

NCT06463587 | RECRUITING | PHASE3

264 participants

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-25
Completion:: 2028-08-23

Conditions

Generalized Myasthenia Gravis

Interventions

OTHER
DRUG

No Results Yet

NCT06458374 | RECRUITING

180 participants

ATTR Cardiac Amyloidosis in a Selected Population

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-09-01
Completion:: 2034-02-28

Conditions

ATTR Amyloidosis Wild Type
ATTR Gene Mutation
Carpal Tunnel Syndrome
Cardiac Amyloidosis

No Results Yet

NCT06457425 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

A Phase II Clinical Trial of Flonoltinib Maleate Tablet in Intermediate-High Risk Myelofibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-06
Completion:: 2025-11-26

Conditions

MF,PMF,PPV-MF,PET-MF

Interventions

DRUG

No Results Yet

NCT06451614 | ACTIVE_NOT_RECRUITING | NA

230 participants

SpaceIT Hydrogel System for Perirectal Spacing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-30
Completion:: 2026-08-30

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT06444113 | ACTIVE_NOT_RECRUITING | PHASE4

24 participants

Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-25
Completion:: 2026-02-20

Conditions

Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT06423729 | COMPLETED | PHASE2

46 participants

Effect of Nicorandil in Type 2 Diabetic Obese Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-11-01
Completion:: 2024-07-30

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT06423716 | RECRUITING | PHASE4

150 participants

Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-01
Completion:: 2027-07-01

Conditions

Knee Osteoarthritis

Interventions

DRUG

No Results Yet

NCT06417255 | COMPLETED | NA

60 participants

Comparison Of The Effects Of Kinesiotape Application And Foam Roller Exercises

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-05-11
Completion:: 2023-07-26

Conditions

Low Back Pain, Mechanical

Interventions

OTHER

No Results Yet

NCT06411899 | COMPLETED | PHASE3

422 participants

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-15
Completion:: 2025-09-02

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

No Results Yet

NCT06404632 | RECRUITING | NA

30 participants

A Group Intervention for Promoting Health-related Habits (LEV-G)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-12
Completion:: 2027-02-28

Conditions

Life Style
Health-Related Behavior
Disabilities Mental
Disability Physical
Acceptability of Health Care

Interventions

BEHAVIORAL

No Results Yet

NCT06402877 | COMPLETED

60 participants

Evaluation of Salivary Adseverin, 1-Alpha Defensin and sRANKL Levels of Individuals With Different Periodontal Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-26
Completion:: 2025-02-25

Conditions

Periodontal Diseases

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06402838 | ACTIVE_NOT_RECRUITING | PHASE2

256 participants

A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-02
Completion:: 2026-11-19

Conditions

Alzheimer's Disease

Interventions

DRUG

No Results Yet

NCT06399718 | COMPLETED | PHASE3

207 participants

A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-30
Completion:: 2025-11-10

Conditions

Masseter Muscle Prominence

Interventions

DRUG

No Results Yet

NCT06393296 | COMPLETED

88 participants

A Study of Melatonin Concentration During Lactation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-17
Completion:: 2025-10-24

Conditions

Breastfeeding

No Results Yet

NCT06385171 | WITHDRAWN

0 participants

Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-22
Completion:: 2026-06-01

Conditions

Wrinkle

Interventions

DRUG

No Results Yet

NCT06371833 | RECRUITING

60 participants

PRIMA EU Retrospective & Prospective

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-25
Completion:: 2030-01-31

Conditions

Arthroplasty
Replacement
Shoulder

Interventions

DEVICE

No Results Yet

NCT06360289 | ACTIVE_NOT_RECRUITING

346 participants

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-25
Completion:: 2027-12-15

Conditions

Hereditary Amyloidosis, Transthyretin-Related
Asymptomatic Carrier State

Interventions

OTHER

No Results Yet

NCT06358521 | COMPLETED | NA

647 participants

Determining the Impact of a Physiotherapist-led Primary Care Model for Hip and Knee Pain - A Cluster Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-10-02
Completion:: 2025-11-25

Conditions

Hip Osteoarthritis
Knee Osteoarthritis

Interventions

OTHER

No Results Yet

NCT06357533 | RECRUITING | PHASE3

675 participants

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-11
Completion:: 2029-12-28

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06340737 | RECRUITING | PHASE1

148 participants

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-03-29
Completion:: 2031-04-30

Conditions

Follicular Lymphoma
Mantle Cell Lymphoma
Hairy Cell Leukemia
Lymphoplasmacytic Lymphoma
Burkitt Lymphoma
Marginal Zone Lymphoma
Waldenstrom Macroglobulinemia
Large B-cell Lymphoma

Interventions

DRUG

No Results Yet

NCT06334016 | NOT_YET_RECRUITING | EARLY_PHASE1

60 participants

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-09-15
Completion:: 2028-03-01

Conditions

Cannabis Dependence

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT06323044 | RECRUITING | NA

150 participants

MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-11
Completion:: 2029-03-31

Conditions

Acute Lymphoblastic Leukemia

Interventions

OTHER
PROCEDURE

No Results Yet

NCT06317077 | COMPLETED | NA

49 participants

Investigation of the Accordance Between Event Detection of prismaLINE Devices and Polysomnography Using Full Face Masks

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-12-02
Completion:: 2026-06-17

Conditions

Sleep Apnea Syndromes

Interventions

OTHER

No Results Yet

NCT06316999 | COMPLETED | NA

66 participants

Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-07-01
Completion:: 2025-06-04

Conditions

Ulcerative Colitis
Pouchitis

Interventions

DIAGNOSTIC_TEST

Results Available

NCT06313593 | ACTIVE_NOT_RECRUITING | PHASE1

37 participants

A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-08-08
Completion:: 2028-10-09

Conditions

Myeloproliferative Neoplasms

Interventions

DRUG

No Results Yet

NCT06300918 | COMPLETED | NA

60 participants

A Clinical Trial to Evaluate the Time Point of Anti-VEGF Pretreatment of PDR Based on Intraoperative FFA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-03-08
Completion:: 2025-02-28

Conditions

The Condition of Fundus Neovascularization

Interventions

OTHER

No Results Yet

NCT06297291 | RECRUITING

1000 participants

Global Paradise System US Post Approval Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-28
Completion:: 2026-09-30

Conditions

Hypertension
Cardiovascular Diseases
Vascular Diseases

Interventions

DEVICE

No Results Yet