Clinical Trials

NCT06561087 | RECRUITING | PHASE2

45 participants

Phase II Randomized, Placebo- Controlled Study of Intralesional Nivolumab for High-risk Oral Premalignant Lesions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-02-27

Completion:

2027-05-30

Conditions

• Premalignant Lesion

Interventions

• DRUG

No Results Yet

NCT06549829 | RECRUITING | NA

120 participants

the Effect of Nutrition-optimized Prehabilitation on Perioperative Intervention in Primary Liver Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-09-01

Completion:

2026-09-30

Conditions

• Hepatocellular Carcinoma
• Liver Carcinoma
• Hepatobiliary Cancers

Interventions

• OTHER

No Results Yet

NCT06546332 | ACTIVE_NOT_RECRUITING

97 participants

Post Market Clinical Follow-Up KeriFuse®

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2022-07-05

Completion:

2025-04-11

Conditions

• Arthritis

Interventions

• DEVICE

No Results Yet

NCT06543576 | RECRUITING | PHASE1/PHASE2

35 participants

External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-07-29

Completion:

2031-01-31

Conditions

• Cervical Adenocarcinoma
• Cervical Adenosquamous Carcinoma
• Cervical Squamous Cell Carcinoma
• Stage IVB Cervical Cancer American Joint Committee on Cancer (AJCC) v8

Interventions

• BIOLOGICAL
• PROCEDURE
• RADIATION
• DRUG
• OTHER

No Results Yet

NCT06542120 | RECRUITING

30000 participants

Research on Body Voice AI Recognition System for Children's Health Management

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2024-05-01

Completion:

2026-12-31

Conditions

• Congenital Heart Disease
• Bronchopneumonia
• Abdominal Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06538285 | COMPLETED | PHASE2

17 participants

Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-03-04

Completion:

2026-05-05

Conditions

• Methamphetamine Use Disorder

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT06531083 | RECRUITING | NA

30 participants

Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-03-01

Completion:

2026-09-30

Conditions

• Head and Neck Cancer
• Trismus

Interventions

• BEHAVIORAL

No Results Yet

NCT06529029 | RECRUITING | PHASE2/PHASE3

30 participants

Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-07-03

Completion:

2026-10-01

Conditions

• Suicidal Ideation
• Major Depressive Disorder
• Schizo Affective Disorder
• Bipolar Disorder

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT06526819 | RECRUITING | PHASE1/PHASE2

120 participants

SMP-3124LP in Adults With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-08-14

Completion:

2028-12-31

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06525766 | RECRUITING | PHASE2

35 participants

Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-10-01

Completion:

2030-10-15

Conditions

• Anatomic Stage IV Breast Cancer AJCC v8
• Estrogen-receptor-positive Breast Cancer
• Metastatic HER2-Negative Breast Carcinoma
• Metastatic Breast Cancer

Interventions

• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT06517758 | ACTIVE_NOT_RECRUITING | PHASE3

146 participants

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-07-31

Completion:

2027-04-30

Conditions

• Generalized Myasthenia Gravis

Interventions

• DRUG
• OTHER

No Results Yet

NCT06512597 | RECRUITING | NA

170 participants

Behavioral Therapy for Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-11-01

Completion:

2027-07-30

Conditions

• Crohn's Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT06511141 | RECRUITING | NA

150 participants

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-10-22

Completion:

2027-12-31

Conditions

• Overactive Bladder
• Urinary Urgency Incontinence
• Benign Prostatic Hyperplasia
• Prostate Cancer
• Prostatectomy
• Urinary Frequency

Interventions

• DEVICE

No Results Yet

NCT06489769 | SUSPENDED

200 participants

Opioid Misuse in Patients With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2025-01-15

Completion:

2026-12-31

Conditions

• Cancer
• Opioid Use
• Opioid Misuse
• Pain
• Cancer Pain

No Results Yet

NCT06487481 | RECRUITING | PHASE1

32 participants

Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-08-17

Completion:

2030-12-01

Conditions

• Adrenocortical Carcinoma (ACC)
• Recurrent Adrenocortical Carcinoma (ACC)
• Recurrent Abdominal Adrenocortical Carcinoma (ACC)
• Carcinoma, Adrenocortical
• Carcinoma, Adrenal Cortical

Interventions

• PROCEDURE
• RADIATION

No Results Yet

NCT06479837 | RECRUITING

500 participants

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2026-08-17

Completion:

2043-12-01

Conditions

• Staphylococcal Infections

No Results Yet

NCT06474676 | RECRUITING | PHASE1

40 participants

T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-09-29

Completion:

2030-12-31

Conditions

• Metastatic Soft-tissue Sarcoma

Interventions

• DRUG

No Results Yet

NCT06468137 | ACTIVE_NOT_RECRUITING | NA

100 participants

Follow Up of an Online Hearing Support for First-time Hearing Aid Users

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-07-01

Completion:

2026-12-31

Conditions

• Hearing Loss
• Hearing Impairment
• Hearing Disorders

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06465199 | RECRUITING | PHASE1/PHASE2

289 participants

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-05-13

Completion:

2033-05-31

Conditions

• Atypical Teratoid/Rhabdoid Tumor
• Embryonal Tumor With Multilayered Rosettes
• Ewing Sarcoma
• Diffuse Intrinsic Pontine Glioma
• Osteosarcoma
• Neuroblastoma
• DIPG Brain Tumor

Interventions

• DRUG

No Results Yet

NCT06464705 | RECRUITING | NA

60 participants

To Investigate the Effect of PEMF for Pateitns After Anterior Cruciate Ligament Reconstruction With Hamstring Autograft

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-06-13

Completion:

2027-03-31

Conditions

• Anterior Cruciate Ligament Reconstruction
• Hamstring Muscle

Interventions

• DEVICE

No Results Yet

NCT06463587 | RECRUITING | PHASE3

264 participants

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-06-25

Completion:

2028-08-23

Conditions

• Generalized Myasthenia Gravis

Interventions

• OTHER
• DRUG

No Results Yet

NCT06458374 | RECRUITING

180 participants

ATTR Cardiac Amyloidosis in a Selected Population

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2024-09-01

Completion:

2034-02-28

Conditions

• ATTR Amyloidosis Wild Type
• ATTR Gene Mutation
• Carpal Tunnel Syndrome
• Cardiac Amyloidosis

No Results Yet

NCT06457425 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

A Phase II Clinical Trial of Flonoltinib Maleate Tablet in Intermediate-High Risk Myelofibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-05-06

Completion:

2025-11-26

Conditions

• MF,PMF,PPV-MF,PET-MF

Interventions

• DRUG

No Results Yet

NCT06451614 | ACTIVE_NOT_RECRUITING | NA

230 participants

SpaceIT Hydrogel System for Perirectal Spacing

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-10-30

Completion:

2026-08-30

Conditions

• Prostate Cancer

Interventions

• DEVICE

No Results Yet

NCT06444113 | ACTIVE_NOT_RECRUITING | PHASE4

24 participants

Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-11-25

Completion:

2026-02-20

Conditions

• Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT06423729 | COMPLETED | PHASE2

46 participants

Effect of Nicorandil in Type 2 Diabetic Obese Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2023-11-01

Completion:

2024-07-30

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT06423716 | RECRUITING | PHASE4

150 participants

Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-11-01

Completion:

2027-07-01

Conditions

• Knee Osteoarthritis

Interventions

• DRUG

No Results Yet

NCT06417255 | COMPLETED | NA

60 participants

Comparison Of The Effects Of Kinesiotape Application And Foam Roller Exercises

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2023-05-11

Completion:

2023-07-26

Conditions

• Low Back Pain, Mechanical

Interventions

• OTHER

No Results Yet

NCT06411899 | COMPLETED | PHASE3

422 participants

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-05-15

Completion:

2025-09-02

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG

No Results Yet

NCT06406465 | RECRUITING | PHASE2

60 participants

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-08-17

Completion:

2027-07-30

Conditions

• Carcinoma, Neuroendocrine
• Tumor, Neuroendocrine
• Tumors, Neuroendocrine
• Neuroendocrine; Carcinoma
• Small Cell; Receptors

Interventions

• DRUG

No Results Yet

NCT06404632 | RECRUITING | NA

30 participants

A Group Intervention for Promoting Health-related Habits (LEV-G)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-04-12

Completion:

2027-02-28

Conditions

• Life Style
• Health-Related Behavior
• Disabilities Mental
• Disability Physical
• Acceptability of Health Care

Interventions

• BEHAVIORAL

No Results Yet

NCT06402877 | COMPLETED

60 participants

Evaluation of Salivary Adseverin, 1-Alpha Defensin and sRANKL Levels of Individuals With Different Periodontal Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2024-06-26

Completion:

2025-02-25

Conditions

• Periodontal Diseases

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06402838 | ACTIVE_NOT_RECRUITING | PHASE2

256 participants

A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-05-02

Completion:

2026-11-19

Conditions

• Alzheimer's Disease

Interventions

• DRUG

No Results Yet

NCT06402383 | ACTIVE_NOT_RECRUITING | NA

2000 participants

Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania Among Women Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-05-25

Completion:

2027-01-31

Conditions

• Cervical Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT06399718 | COMPLETED | PHASE3

207 participants

A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-04-30

Completion:

2025-11-10

Conditions

• Masseter Muscle Prominence

Interventions

• DRUG

No Results Yet

NCT06393296 | COMPLETED

88 participants

A Study of Melatonin Concentration During Lactation

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2024-04-17

Completion:

2025-10-24

Conditions

• Breastfeeding

No Results Yet

NCT06385171 | WITHDRAWN

0 participants

Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2024-05-22

Completion:

2026-06-01

Conditions

• Wrinkle

Interventions

• DRUG

No Results Yet

NCT06371833 | RECRUITING

60 participants

PRIMA EU Retrospective & Prospective

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2024-10-25

Completion:

2030-01-31

Conditions

• Arthroplasty
• Replacement
• Shoulder

Interventions

• DEVICE

No Results Yet

NCT06370208 | ACTIVE_NOT_RECRUITING | NA

82 participants

Prophylactic Effect of Probiotic Streptococcus Salivarius eK12 Against Recurrent Streptococcus Pyogenes Pharyngotonsillitis Infection in Pediatrics

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-12-01

Completion:

2026-07-31

Conditions

• Streptococcus Pyogenes Pharyngotonsillitis

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT06360289 | ACTIVE_NOT_RECRUITING

346 participants

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2024-04-25

Completion:

2027-12-15

Conditions

• Hereditary Amyloidosis, Transthyretin-Related
• Asymptomatic Carrier State

Interventions

• OTHER

No Results Yet