Clinical Trials Updated in 2026

NCT06525766 | RECRUITING | PHASE2

35 participants

Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-10-01
Completion:: 2030-10-15

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Estrogen-receptor-positive Breast Cancer
Metastatic HER2-Negative Breast Carcinoma
Metastatic Breast Cancer

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT06517758 | ACTIVE_NOT_RECRUITING | PHASE3

146 participants

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-07-31
Completion:: 2027-04-30

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG
OTHER

No Results Yet

NCT06512597 | RECRUITING | NA

170 participants

Behavioral Therapy for Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-01
Completion:: 2027-07-30

Conditions

Crohn's Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06511141 | RECRUITING | NA

150 participants

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-22
Completion:: 2027-12-31

Conditions

Overactive Bladder
Urinary Urgency Incontinence
Benign Prostatic Hyperplasia
Prostate Cancer
Prostatectomy
Urinary Frequency

Interventions

DEVICE

No Results Yet

NCT06489769 | SUSPENDED

200 participants

Opioid Misuse in Patients With Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-15
Completion:: 2026-12-31

Conditions

Cancer
Opioid Use
Opioid Misuse
Pain
Cancer Pain

No Results Yet

NCT06468137 | ACTIVE_NOT_RECRUITING | NA

100 participants

Follow Up of an Online Hearing Support for First-time Hearing Aid Users

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-07-01
Completion:: 2026-12-31

Conditions

Hearing Loss
Hearing Impairment
Hearing Disorders

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06464705 | RECRUITING | NA

60 participants

To Investigate the Effect of PEMF for Pateitns After Anterior Cruciate Ligament Reconstruction With Hamstring Autograft

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-13
Completion:: 2027-03-31

Conditions

Anterior Cruciate Ligament Reconstruction
Hamstring Muscle

Interventions

DEVICE

No Results Yet

NCT06463587 | RECRUITING | PHASE3

264 participants

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-25
Completion:: 2028-08-23

Conditions

Generalized Myasthenia Gravis

Interventions

OTHER
DRUG

No Results Yet

NCT06458374 | RECRUITING

180 participants

ATTR Cardiac Amyloidosis in a Selected Population

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-09-01
Completion:: 2034-02-28

Conditions

ATTR Amyloidosis Wild Type
ATTR Gene Mutation
Carpal Tunnel Syndrome
Cardiac Amyloidosis

No Results Yet

NCT06457425 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

A Phase II Clinical Trial of Flonoltinib Maleate Tablet in Intermediate-High Risk Myelofibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-06
Completion:: 2025-11-26

Conditions

MF,PMF,PPV-MF,PET-MF

Interventions

DRUG

No Results Yet

NCT06451614 | ACTIVE_NOT_RECRUITING | NA

230 participants

SpaceIT Hydrogel System for Perirectal Spacing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-30
Completion:: 2026-08-30

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT06444113 | ACTIVE_NOT_RECRUITING | PHASE4

24 participants

Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-25
Completion:: 2026-02-20

Conditions

Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT06423729 | COMPLETED | PHASE2

46 participants

Effect of Nicorandil in Type 2 Diabetic Obese Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-11-01
Completion:: 2024-07-30

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT06423716 | RECRUITING | PHASE4

150 participants

Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-01
Completion:: 2027-07-01

Conditions

Knee Osteoarthritis

Interventions

DRUG

No Results Yet

NCT06417255 | COMPLETED | NA

60 participants

Comparison Of The Effects Of Kinesiotape Application And Foam Roller Exercises

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-05-11
Completion:: 2023-07-26

Conditions

Low Back Pain, Mechanical

Interventions

OTHER

No Results Yet

NCT06411899 | COMPLETED | PHASE3

422 participants

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-15
Completion:: 2025-09-02

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

No Results Yet

NCT06404632 | RECRUITING | NA

30 participants

A Group Intervention for Promoting Health-related Habits (LEV-G)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-12
Completion:: 2027-02-28

Conditions

Life Style
Health-Related Behavior
Disabilities Mental
Disability Physical
Acceptability of Health Care

Interventions

BEHAVIORAL

No Results Yet

NCT06402877 | COMPLETED

60 participants

Evaluation of Salivary Adseverin, 1-Alpha Defensin and sRANKL Levels of Individuals With Different Periodontal Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-26
Completion:: 2025-02-25

Conditions

Periodontal Diseases

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06402838 | ACTIVE_NOT_RECRUITING | PHASE2

256 participants

A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-02
Completion:: 2026-11-19

Conditions

Alzheimer's Disease

Interventions

DRUG

No Results Yet

NCT06399718 | COMPLETED | PHASE3

207 participants

A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-30
Completion:: 2025-11-10

Conditions

Masseter Muscle Prominence

Interventions

DRUG

No Results Yet

NCT06393296 | COMPLETED

88 participants

A Study of Melatonin Concentration During Lactation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-17
Completion:: 2025-10-24

Conditions

Breastfeeding

No Results Yet

NCT06385171 | WITHDRAWN

0 participants

Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-05-22
Completion:: 2026-06-01

Conditions

Wrinkle

Interventions

DRUG

No Results Yet

NCT06371833 | RECRUITING

60 participants

PRIMA EU Retrospective & Prospective

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-25
Completion:: 2030-01-31

Conditions

Arthroplasty
Replacement
Shoulder

Interventions

DEVICE

No Results Yet

NCT06360289 | ACTIVE_NOT_RECRUITING

346 participants

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-25
Completion:: 2027-12-15

Conditions

Hereditary Amyloidosis, Transthyretin-Related
Asymptomatic Carrier State

Interventions

OTHER

No Results Yet

NCT06358521 | COMPLETED | NA

647 participants

Determining the Impact of a Physiotherapist-led Primary Care Model for Hip and Knee Pain - A Cluster Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-10-02
Completion:: 2025-11-25

Conditions

Hip Osteoarthritis
Knee Osteoarthritis

Interventions

OTHER

No Results Yet

NCT06357533 | RECRUITING | PHASE3

675 participants

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-04-11
Completion:: 2029-12-28

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06340737 | RECRUITING | PHASE1

148 participants

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-03-29
Completion:: 2031-04-30

Conditions

Follicular Lymphoma
Mantle Cell Lymphoma
Hairy Cell Leukemia
Lymphoplasmacytic Lymphoma
Burkitt Lymphoma
Marginal Zone Lymphoma
Waldenstrom Macroglobulinemia
Large B-cell Lymphoma

Interventions

DRUG

No Results Yet

NCT06334016 | NOT_YET_RECRUITING | EARLY_PHASE1

60 participants

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-09-15
Completion:: 2028-03-01

Conditions

Cannabis Dependence

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT06323044 | RECRUITING | NA

150 participants

MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-11
Completion:: 2029-03-31

Conditions

Acute Lymphoblastic Leukemia

Interventions

OTHER
PROCEDURE

No Results Yet

NCT06317077 | COMPLETED | NA

49 participants

Investigation of the Accordance Between Event Detection of prismaLINE Devices and Polysomnography Using Full Face Masks

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-12-02
Completion:: 2026-06-17

Conditions

Sleep Apnea Syndromes

Interventions

OTHER

No Results Yet

NCT06316999 | COMPLETED | NA

66 participants

Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-07-01
Completion:: 2025-06-04

Conditions

Ulcerative Colitis
Pouchitis

Interventions

DIAGNOSTIC_TEST

Results Available

NCT06313593 | ACTIVE_NOT_RECRUITING | PHASE1

37 participants

A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-08-08
Completion:: 2028-10-09

Conditions

Myeloproliferative Neoplasms

Interventions

DRUG

No Results Yet

NCT06300918 | COMPLETED | NA

60 participants

A Clinical Trial to Evaluate the Time Point of Anti-VEGF Pretreatment of PDR Based on Intraoperative FFA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-03-08
Completion:: 2025-02-28

Conditions

The Condition of Fundus Neovascularization

Interventions

OTHER

No Results Yet

NCT06297291 | RECRUITING

1000 participants

Global Paradise System US Post Approval Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-28
Completion:: 2026-09-30

Conditions

Hypertension
Cardiovascular Diseases
Vascular Diseases

Interventions

DEVICE

No Results Yet

NCT06294587 | RECRUITING | NA

30 participants

Evaluation of Free Gingival Graft Timing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-08-12
Completion:: 2027-08-30

Conditions

Ridge Augmentation
Alveolar Mucosa

Interventions

PROCEDURE

No Results Yet

NCT06289582 | RECRUITING | EARLY_PHASE1

60 participants

Longitudinal TSPO PET Imaging With [18F]DPA-714 in PPMI (PPMI DPA-714 PET Imaging)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-08-14
Completion:: 2028-06-30

Conditions

Parkinson Disease

Interventions

DRUG

No Results Yet

NCT06289049 | COMPLETED | PHASE2

37 participants

Heavy Strength Training in Head and Neck Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-17
Completion:: 2026-07-06

Conditions

Head and Neck Neoplasms
Head and Neck Cancer
Head and Neck Squamous Cell Carcinoma
Head and Neck Carcinoma

Interventions

OTHER

No Results Yet

NCT06284837 | COMPLETED | NA

542 participants

Secondary Access - FEmoral or Radial in Transcatheter Aortic Valve Implantation?

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-02-02
Completion:: 2026-06-10

Conditions

Valve Stenoses, Aortic

Interventions

OTHER

No Results Yet

NCT06283992 | COMPLETED | NA

64 participants

Digital Health Navigation for Latino Patients With Type II Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-03-31
Completion:: 2026-06-30

Conditions

Type 2 Diabetes

Interventions

OTHER

No Results Yet

NCT06266507 | COMPLETED | NA

39 participants

Examining the Effect of Occupational Therapy-Based Parent Coaching on Feeding Problems in Children With a Preterm Birth

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-07-29
Completion:: 2025-06-22

Conditions

Feeding Behavior
Mother-Child Relations
Feeding and Eating Disorders

Interventions

BEHAVIORAL
OTHER

No Results Yet