Clinical Trials

NCT05124119 | COMPLETED

63 participants

Strategies to Enhance Recruitment and Retention of Black Individuals Into Clinical Trials for Substance Use Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-04-01
Completion:: 2022-12-01

Conditions

Substance Use Disorders

Results Available

NCT05123482 | RECRUITING | PHASE1/PHASE2

460 participants

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-10-18
Completion:: 2027-09-29

Conditions

Breast Cancer
Biliary Tract Carcinoma
Ovarian Cancer
Endometrial Cancer
Squamous Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05113836 | COMPLETED

89 participants

LIPId Profile Changes in Inflammatory Conditions Induced by SARS-CORoronavirus-2

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-01-06
Completion:: 2022-04-08

Conditions

SARS-CoV2 Infection

Interventions

BIOLOGICAL

No Results Yet

NCT05102799 | ACTIVE_NOT_RECRUITING

200 participants

MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Variants

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-04-01
Completion:: 2026-06-01

Conditions

Limb Girdle Muscular Dystrophy

Interventions

OTHER

No Results Yet

NCT05102019 | RECRUITING | NA

380 participants

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-01-04
Completion:: 2027-07-31

Conditions

Refractory Angina

Interventions

DEVICE
OTHER

No Results Yet

NCT05099172 | RECRUITING | PHASE1/PHASE2

400 participants

First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-10-25
Completion:: 2026-03-16

Conditions

Advanced Non-small Cell Lung Cancer
EGFR Mutation
HER2 Mutation

Interventions

DRUG

No Results Yet

NCT05092295 | ACTIVE_NOT_RECRUITING

200 participants

Head and Intraocular Trauma Tool for the Identification of Mild Traumatic Brain Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-12-01
Completion:: 2027-12-31

Conditions

Brain Injuries, Traumatic

Interventions

DEVICE
DIAGNOSTIC_TEST

No Results Yet

NCT05092282 | COMPLETED

10 participants

HITT for the Identification of Mild Traumatic Brain Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-08-01
Completion:: 2025-12-31

Conditions

Brain Injuries, Traumatic

Interventions

DEVICE
DIAGNOSTIC_TEST

No Results Yet

NCT05091242 | RECRUITING | PHASE2/PHASE3

336 participants

The PREVENT AGITATION Trial II - Children ≤1 Year

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-10-25
Completion:: 2028-01-31

Conditions

Emergence Delirium

Interventions

DRUG

No Results Yet

NCT05090397 | COMPLETED | NA

26 participants

MRI-Guided High-Definition Transcranial Direct Current Stimulation (tDCS) for Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-07-01
Completion:: 2025-03-31

Conditions

Depression

Interventions

DEVICE

No Results Yet

NCT05072314 | RECRUITING | PHASE3

4300 participants

Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-07-27
Completion:: 2028-05-31

Conditions

Breast Cancer
Breast Cancer Female
Breast Conserving Surgery
Mastectomy

Interventions

DRUG

No Results Yet

NCT05071612 | COMPLETED | PHASE2

294 participants

Parallel Arm Trial of AD109 and AD504 In Patients With OSA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-11-29
Completion:: 2022-07-20

Conditions

OSA - Obstructive Sleep Apnea

Interventions

DRUG

Results Available

NCT05063916 | ACTIVE_NOT_RECRUITING | PHASE2

18 participants

Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the Cervix

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-02-28
Completion:: 2027-08-01

Conditions

Carcinomas
Cervix Cancer
Cervical Cancer

Interventions

DRUG

No Results Yet

NCT05047224 | COMPLETED | NA

664 participants

Addressing Disparities in Autism Spectrum Disorder Diagnosis Using a Direct-to-home Telemedicine Tool

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-12-03
Completion:: 2026-03-10

Conditions

Autism Spectrum Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05046301 | ACTIVE_NOT_RECRUITING

59 participants

Contrast-Enhanced Mammography for the Evaluation of Mammographic Microcalcifications

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-03-23
Completion:: 2027-02-02

Conditions

Breast Carcinoma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05040087 | ACTIVE_NOT_RECRUITING | NA

127 participants

Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-09-01
Completion:: 2026-12-31

Conditions

Type 2 Diabetes

Interventions

OTHER

No Results Yet

NCT05030441 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-04-01
Completion:: 2030-01-31

Conditions

Clonal Cytopenia of Undetermined Significance

Interventions

DRUG

No Results Yet

NCT05025293 | COMPLETED | PHASE4

228 participants

Zoledronate Early to Hip Fracture Patients - Safe and Effective?

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-12-15
Completion:: 2026-06-11

Conditions

Hip Fractures
Osteoporosis

Interventions

DRUG

No Results Yet

NCT05016245 | COMPLETED | PHASE3

92 participants

MANDARIN (S6371)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-09-13
Completion:: 2026-02-13

Conditions

Inoperable Hepatocellular Carcinoma

Interventions

COMBINATION_PRODUCT
PROCEDURE

No Results Yet

NCT04990128 | NOT_YET_RECRUITING | PHASE3

100 participants

Bone Marrow Aspirate Concentrate Versus Triamcinolone Injection For Hip Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-09-30
Completion:: 2027-10-31

Conditions

Hip Osteoarthritis

Interventions

COMBINATION_PRODUCT
DRUG

No Results Yet

NCT04987879 | COMPLETED | NA

20 participants

NASH AMPK Exercise Dosing (AMPED) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-08-30
Completion:: 2026-02-10

Conditions

NAFLD

Interventions

BEHAVIORAL

No Results Yet

NCT04965454 | RECRUITING | PHASE2

80 participants

Evaluation of Treatment Predictors Reflecting Beta-catenin Activation in Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-03-28
Completion:: 2027-12-31

Conditions

Hepatocellular Carcinoma Non-resectable

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT04951453 | COMPLETED

150 participants

Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-08-18
Completion:: 2024-04-30

Conditions

Subarachnoid Hemorrhage, Aneurysmal
Intracerebral Hemorrhage
Traumatic Brain Injury

Interventions

OTHER

No Results Yet

NCT04905069 | ACTIVE_NOT_RECRUITING | NA

500 participants

Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-12-21
Completion:: 2027-12-31

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT04902066 | COMPLETED | NA

259 participants

Face Your Fears: Cognitive Behavioural Virtual Reality Therapy for "Paranoia".

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-04-09
Completion:: 2024-03-21

Conditions

Paranoid Schizophrenia
Schizophrenia and Related Disorders
Schizophrenia Prodromal
Schizotypal Disorder
Paranoid Ideation
Paranoid Delusion
Ideas of Reference
Psychosis Paranoid
Psychotic Disorders
Psychotic Paranoia
Psychotic; Disorder, Delusional

Interventions

OTHER

No Results Yet

NCT04862221 | ACTIVE_NOT_RECRUITING | PHASE2

44 participants

TReatment for ImmUne Mediated PathopHysiology

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-02-09
Completion:: 2026-08-03

Conditions

Acute Liver Failure
Fulminant Hepatic Failure
Hepatic Encephalopathy
Acute Liver Injury
Immune Dysregulation

Interventions

DRUG

No Results Yet

NCT04856722 | COMPLETED | NA

255 participants

Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-04-05
Completion:: 2024-06-04

Conditions

Renal Stone
Percutaneous Nephrolithotomy
Retrograde Intrarenal Surgery
Extracorporeal Shockwave Lithotripsy

Interventions

PROCEDURE

No Results Yet

NCT04852965 | COMPLETED

103 participants

Late Anthracycline Induced Cardiotoxicity- Childhood Cancer Survivors

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-10-20
Completion:: 2024-04-15

Conditions

Anthracycline Induced Cardiotoxicity

No Results Yet

NCT04849923 | COMPLETED | NA

23 participants

Validation of a Digital Twin Performing Strength Training

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-01-01
Completion:: 2025-10-31

Conditions

Healthy

Interventions

OTHER

Results Available

NCT04838769 | ACTIVE_NOT_RECRUITING | NA

155 participants

REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-09-15
Completion:: 2025-12-11

Conditions

Benign Prostatic Hyperplasia (BPH)

Interventions

DEVICE
DRUG

No Results Yet

NCT04775706 | RECRUITING | PHASE2

18 participants

Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-03-03
Completion:: 2027-12-31

Conditions

Short Bowel Syndrome

Interventions

DRUG

No Results Yet

NCT04769388 | COMPLETED | PHASE2

80 participants

Osimertinib Plus Chemotherapy vs Osimertinib in EGFRm NSCLC With Persistence Week-3 ctDNA EGFRm After 1L Osimertinib

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-12-28
Completion:: 2026-01-24

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT04768426 | RECRUITING | PHASE2

40 participants

Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-02-03
Completion:: 2026-11-30

Conditions

Triple Negative Breast Cancer
Breast Cancer

Interventions

DRUG

No Results Yet

NCT04762888 | COMPLETED | PHASE2

52 participants

68Ga-PSMA-Dual-Contrast PET/MRI or PET/CT for Early Detection of Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-02-24
Completion:: 2025-06-26

Conditions

Hepatocellular Carcinoma

Interventions

PROCEDURE
DRUG

Results Available

NCT04748861 | ACTIVE_NOT_RECRUITING | NA

150 participants

CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-10-20
Completion:: 2026-12-31

Conditions

High Intensity Exercise
Normal Cognition
Exercise Intervention

Interventions

OTHER

No Results Yet

NCT04746703 | COMPLETED | NA

25 participants

New Imaging Tools to Explore Impact of Bariatric Surgery on Pancreatic Lesions: PACHIBA- Bariatric Surg

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-02-10
Completion:: 2023-09-16

Conditions

Bariatric Surgery

Interventions

RADIATION

No Results Yet

NCT04737577 | COMPLETED | NA

44 participants

Glioma Supra Marginal Incision Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-02-05
Completion:: 2025-12-30

Conditions

High Grade Glioma

Interventions

PROCEDURE

No Results Yet

NCT04732052 | RECRUITING | NA

60 participants

The Use of Transcranial Direct Current Stimulation (tDCS) in Adults With Developmental Disabilities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-09-01
Completion:: 2027-09-30

Conditions

Aggression

Interventions

DEVICE

No Results Yet

NCT04731025 | ACTIVE_NOT_RECRUITING | PHASE3

1003 participants

Local Antibiotics for Breast Implants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-01-27
Completion:: 2026-09-26

Conditions

Implant Complication
Implant Infection
Implant Site Infection
Implant Capsular Contracture
Implant Site Pocket Infection
Implant Expulsion
Antibiotic Side Effect

Interventions

DRUG
OTHER

No Results Yet

NCT04707300 | RECRUITING | PHASE1/PHASE2

10 participants

Study Evaluating the Safety and the Efficacy of Human T Lymphoid Progenitor (HTLP) Injection to Accelerate Immune Reconstitution After Umbilical Cord Blood (UCB) Transplantation in Adult Patients With Hematologic Malignancies (HTLP-ONCO)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-02-16
Completion:: 2027-06-30

Conditions

Hematologic Malignancy

Interventions

DRUG

No Results Yet