Clinical Trials

NCT04068610 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

61 participants

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-09-13

Completion:

2022-10-10

Conditions

• Metastatic Microsatellite-stable Colorectal Cancer

Interventions

• DRUG

Results Available

NCT04065477 | ACTIVE_NOT_RECRUITING | NA

9 participants

Improving Time-Based Prospective Memory in TBI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-10-01

Completion:

2023-03-31

Conditions

• Traumatic Brain Injury

Interventions

• BEHAVIORAL

No Results Yet

NCT04010305 | COMPLETED | PHASE1

135 participants

Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-05-22

Completion:

2019-07-31

Conditions

• Agitation
• Schizophrenia

Interventions

• DRUG

No Results Yet

NCT03967223 | ACTIVE_NOT_RECRUITING | PHASE2

103 participants

Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-12-31

Completion:

2024-03-01

Conditions

• Neoplasms

Interventions

• DRUG

No Results Yet

NCT03927885 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

100 participants

Open Labeled Placebo in Reducing Cancer Related Fatigue in Patients With Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-03-30

Completion:

2026-12-31

Conditions

• Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm
• Recurrent Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT03866382 | RECRUITING | PHASE2

314 participants

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-05-13

Completion:

2027-02-28

Conditions

• Bladder Adenocarcinoma
• Bladder Clear Cell Adenocarcinoma
• Bladder Mixed Adenocarcinoma
• Bladder Neuroendocrine Carcinoma
• Bladder Small Cell Neuroendocrine Carcinoma
• Bladder Squamous Cell Carcinoma
• Chromophobe Renal Cell Carcinoma
• Collecting Duct Carcinoma
• Invasive Bladder Giant Cell Urothelial Carcinoma
• Invasive Bladder Lymphoepithelioma-Like Carcinoma
• Invasive Bladder Nested Urothelial Carcinoma
• Invasive Bladder Plasmacytoid Urothelial Carcinoma
• Invasive Bladder Sarcomatoid Urothelial Carcinoma
• Invasive Bladder Urothelial Carcinoma
• Kidney Medullary Carcinoma
• Large Cell Neuroendocrine Carcinoma
• Malignant Testicular Leydig Cell Tumor
• Malignant Testicular Sertoli Cell Tumor
• Metastatic Bladder Carcinoma
• Metastatic Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma
• Metastatic Bladder Giant Cell Urothelial Carcinoma
• Metastatic Bladder Large Cell Neuroendocrine Carcinoma
• Metastatic Bladder Lipid-Rich Urothelial Carcinoma
• Metastatic Bladder Micropapillary Urothelial Carcinoma
• Metastatic Bladder Plasmacytoid Urothelial Carcinoma
• Metastatic Bladder Sarcomatoid Urothelial Carcinoma
• Metastatic Bladder Small Cell Neuroendocrine Carcinoma
• Metastatic Bladder Squamous Cell Carcinoma
• Metastatic Chromophobe Renal Cell Carcinoma
• Metastatic Kidney Medullary Carcinoma
• Metastatic Malignant Genitourinary System Neoplasm
• Metastatic Papillary Renal Cell Carcinoma
• Metastatic Penile Carcinoma
• Metastatic Prostate Small Cell Neuroendocrine Carcinoma
• Metastatic Sarcomatoid Renal Cell Carcinoma
• Metastatic Urethral Carcinoma
• Papillary Renal Cell Carcinoma
• Sarcomatoid Renal Cell Carcinoma
• Stage IV Bladder Cancer AJCC v8
• Stage IV Penile Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8
• Stage IV Urethral Cancer AJCC v8
• Stage IVB Prostate Cancer AJCC v8
• Urachal Adenocarcinoma
• Urethral Clear Cell Adenocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT03830229 | RECRUITING

1000 participants

Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2019-03-13

Completion:

2032-12-31

Conditions

• Mesothelioma
• Families

No Results Yet

NCT03813615 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

60 participants

Study of the Effects of Pre-surgical Aerobic Exercise on Patients With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-01-21

Completion:

2027-01-31

Conditions

• Preoperative Aerobic Training
• Solid Tumors

Interventions

• BEHAVIORAL

No Results Yet

NCT03771430 | COMPLETED | NA

282 participants

A Multidisciplinary Intervention in Total Knee Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-08-28

Completion:

2025-04-30

Conditions

• Osteoarthritis; Primary
• Degenerative Joint Disease of Knee

Interventions

• BEHAVIORAL
• PROCEDURE

No Results Yet

NCT03739372 | COMPLETED | NA

44 participants

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-11-28

Completion:

2023-12-31

Conditions

• Glioma
• Glioma of Brain
• Cancer
• Pediatric Cancer
• Pediatric Brain Tumor
• Astrocytoma
• Glioblastoma
• Hemispheric

Interventions

• OTHER

No Results Yet

NCT03708224 | ACTIVE_NOT_RECRUITING | PHASE2

55 participants

Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-03-08

Completion:

2027-07-31

Conditions

• Cancer
• Carcinoma
• Squamous Cell Carcinoma
• Head and Neck Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03656536 | TERMINATED | PHASE3

167 participants

A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-06-03

Completion:

2025-07-07

Conditions

• Unresectable Cholangiocarcinoma
• Metastatic Cholangiocarcinoma

Interventions

• DRUG

Results Available

NCT03654404 | COMPLETED | NA

29 participants

A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-09-11

Completion:

2021-03-31

Conditions

• Hematologic Malignancy
• Hematopoietic/Lymphoid Cancer
• Blood Cancer

Interventions

• BEHAVIORAL

Results Available

NCT03629743 | COMPLETED

20 participants

Correlate of Surface Electroencephalogram (EEG) With Implanted EEG Recordings (ECOG)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2019-11-11

Completion:

2026-08-09

Conditions

• Anesthesia

Interventions

• DEVICE

No Results Yet

NCT03628560 | TERMINATED | NA

2 participants

Alternate Methodology of Pulse Oximeter Validation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-09-26

Completion:

2019-01-02

Conditions

• Hypoxemia
• Desaturation of Blood

Interventions

• DEVICE

Results Available

NCT03606161 | ACTIVE_NOT_RECRUITING | NA

32 participants

Navigated Repetitive Transcranial Magnetic Stimulation in Improving Motor Rehabilitation in Participants With Brain Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-08-23

Completion:

2027-12-31

Conditions

• Brain Neoplasm

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT03600701 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-11-29

Completion:

2025-07-14

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Refractory Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

Results Available

NCT03587662 | COMPLETED | PHASE2

30 participants

Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-08-17

Completion:

2026-08-04

Conditions

• Metastatic Kidney Medullary Carcinoma
• Metastatic Renal Cell Carcinoma
• SMARCB1 Negative
• Stage III Renal Cell Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• DRUG

No Results Yet

NCT03575832 | ACTIVE_NOT_RECRUITING | NA

64 participants

Watchful Living in Improving Quality of Life in Participants With Localized Prostate Cancer on Active Surveillance and Their Partners

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-01-25

Completion:

2028-12-31

Conditions

• Stage I Prostate Cancer AJCC v8
• Stage II Prostate Cancer AJCC v8
• Stage IIA Prostate Cancer AJCC v8
• Stage IIB Prostate Cancer AJCC v8
• Stage IIC Prostate Cancer AJCC v8
• Stage III Prostate Cancer AJCC v8
• Stage IIIA Prostate Cancer AJCC v8
• Stage IIIB Prostate Cancer AJCC v8
• Stage IIIC Prostate Cancer AJCC v8

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT03573700 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

24 participants

Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-07-24

Completion:

2023-07-01

Conditions

• Acute Lymphoblastic Leukemia, in Relapse
• Acute Lymphoblastic Leukemia, Refractory

Interventions

• DRUG
• DEVICE
• BIOLOGICAL

Results Available

NCT03571373 | RECRUITING

1500 participants

PIBD-SETQuality: the Inception Cohort and Safety Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2017-01-03

Completion:

2030-12-31

Conditions

• Inflammatory Bowel Diseases
• Crohn Disease
• Ulcerative Colitis

Interventions

• OTHER

No Results Yet

NCT03545607 | TERMINATED | PHASE3

206 participants

MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-07-28

Completion:

2024-10-01

Conditions

• Ischemic Stroke

Interventions

• BIOLOGICAL

No Results Yet

NCT03527992 | COMPLETED | NA

59 participants

Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-03-09

Completion:

2024-10-03

Conditions

• Pneumonia
• Pneumonia, Ventilator-Associated
• Length of Stay

Interventions

• DEVICE

No Results Yet

NCT03506061 | COMPLETED | PHASE2

42 participants

Trikafta in Cystic Fibrosis Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-09-04

Completion:

2024-02-13

Conditions

• Cystic Fibrosis

Interventions

• DRUG

Results Available

NCT03505762 | ACTIVE_NOT_RECRUITING | PHASE2

80 participants

Tailored Prednisone Reduction in Preventing Hyperglycemia in Participants With B-Cell Non-Hodgkin Lymphoma Receiving Combination Chemotherapy Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-07-19

Completion:

2024-03-28

Conditions

• B-Cell Non-Hodgkin Lymphoma

Interventions

• DRUG
• OTHER
• BIOLOGICAL

Results Available

NCT03495882 | COMPLETED | PHASE1/PHASE2

175 participants

A Study of Zalifrelimab and Balstilimab for Treatment of Participants With Metastatic or Locally Advanced Solid Tumors, and Expansion Into Select Solid Tumors (Cervical)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2017-12-18

Completion:

2022-07-15

Conditions

• Cervical Cancer

Interventions

• DRUG

Results Available

NCT03448003 | ACTIVE_NOT_RECRUITING | NA

60 participants

Comprehensive Lifestyle Change To Prevent Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-04-04

Completion:

2027-08-31

Conditions

• Premenopausal

Interventions

• OTHER

No Results Yet

NCT03424421 | ACTIVE_NOT_RECRUITING | NA

15 participants

Anterior Shoulder Instability Treated With a Semitendinosus Subscapular Sling Procedure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2017-12-20

Completion:

2024-02-05

Conditions

• Anterior Shoulder Dislocation
• Joint Instability

Interventions

• PROCEDURE

No Results Yet

NCT03422302 | RECRUITING | NA

30 participants

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-03-16

Completion:

2028-05-31

Conditions

• Lung Carcinoma
• Malignant Respiratory Tract Neoplasm
• Metastatic Malignant Neoplasm in the Lung

Interventions

• DEVICE
• PROCEDURE
• RADIATION

No Results Yet

NCT03408353 | RECRUITING

10000 participants

Mammography, Early Detection Biomarkers, Risk Assessment, and Imaging Technologies, MERIT Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2017-09-15

Completion:

2027-04-30

Conditions

• Breast Carcinoma

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT03392246 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-01-31

Completion:

2027-06-30

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT03391778 | ENROLLING_BY_INVITATION | PHASE1

250 participants

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-04-09

Completion:

2032-04-01

Conditions

• Neoplasms

Interventions

• BIOLOGICAL

No Results Yet

NCT03385499 | COMPLETED | NA

70 participants

New Diagnostic Approach for Congenital Toxoplasmosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-06-20

Completion:

2023-12-25

Conditions

• Congenital Toxoplasmosis

Interventions

• BIOLOGICAL

No Results Yet

NCT03381287 | COMPLETED | PHASE1/PHASE2

50 participants

A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-04-13

Completion:

2018-12-31

Conditions

• Hypercholesterolemia

Interventions

• DRUG

Results Available

NCT03307980 | COMPLETED | PHASE2

21 participants

Long-term Safety and Efficacy Study and Dose-Escalation Substudy of PF 06838435 in Individuals With Hemophilia B

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2017-06-22

Completion:

2026-07-23

Conditions

• Hemophilia B

Interventions

• BIOLOGICAL

No Results Yet

NCT03220022 | ACTIVE_NOT_RECRUITING | PHASE1

46 participants

Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-03-16

Completion:

2024-10-10

Conditions

• AIDS-Related Lymphoma
• Ann Arbor Stage II Diffuse Large B-Cell Lymphoma
• Ann Arbor Stage III Diffuse Large B-Cell Lymphoma
• Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL
• OTHER

Results Available

NCT03215095 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

11 participants

RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2017-07-10

Completion:

2023-02-06

Conditions

• Thyroid Cancer

Interventions

• DRUG
• RADIATION

Results Available

NCT03199209 | ACTIVE_NOT_RECRUITING | NA

600 participants

Your Health Matters! (Tu Salud ¡Si Cuenta!): Promoting Healthy Lifestyles in Latino Families

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2016-06-06

Completion:

2028-12-31

Conditions

• Family Member
• Health Status Unknown

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT03099603 | COMPLETED | PHASE1

32 participants

A Study of HTD1801 in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2017-03-24

Completion:

2017-07-11

Conditions

• Primary Sclerosing Cholangitis

Interventions

• DRUG

No Results Yet

NCT03081910 | RECRUITING | PHASE1

54 participants

Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2017-11-01

Completion:

2028-06-01

Conditions

• T-cell Acute Lymphoblastic Lymphoma
• T-non-Hodgkin Lymphoma
• T-cell Acute Lymphoblastic Leukemia

Interventions

• GENETIC

No Results Yet