Clinical Trials

NCT07227207 | RECRUITING | PHASE1/PHASE2

72 participants

A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-04-21

Completion:

2029-03-31

Conditions

• Alpha-1 Antitrypsin Deficiency (AATD)

Interventions

• DRUG

No Results Yet

NCT07226531 | COMPLETED

300 participants

Utilization and Effectiveness of Ritlecitinib in a Real-World Population With Severe AA in the US

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-12-22

Completion:

2026-03-06

Conditions

• Alopecia Areata

Interventions

• DRUG

No Results Yet

NCT07226128 | RECRUITING | NA

150 participants

The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-04-10

Completion:

2031-06-30

Conditions

• HIV
• Depression in Adults
• Insulin Resistance
• Cognitive Behavior Therapy

Interventions

• BEHAVIORAL

No Results Yet

NCT07225400 | NOT_YET_RECRUITING | NA

30 participants

Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-10-01

Completion:

2027-12-23

Conditions

• Mild Cognitive Impairment (MCI)

Interventions

• BEHAVIORAL

No Results Yet

NCT07224919 | COMPLETED | NA

30 participants

AutoFocus360 Sound Quality Preference and Claims Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-11-27

Completion:

2026-03-19

Conditions

• Hearing Loss

Interventions

• DEVICE

Results Available

NCT07221552 | RECRUITING | NA

16 participants

Evaluation of the PPAL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-01-20

Completion:

2026-10-31

Conditions

• Age Problems

Interventions

• DEVICE

No Results Yet

NCT07221032 | NOT_YET_RECRUITING | PHASE1

12 participants

FT836 CAR T-cell Therapy in Combination With Daratumumab in Patients With Relapsed and/or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-10-31

Completion:

2028-03-31

Conditions

• Relapse Multiple Myeloma
• Refractory Multiple Myeloma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT07220564 | RECRUITING | PHASE1

30 participants

A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-23

Completion:

2027-02-05

Conditions

• Haemophilia A

Interventions

• DRUG

No Results Yet

NCT07219719 | RECRUITING | PHASE1

40 participants

Temporal Interference for Thalamocortical Activity and Network Modulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-12-01

Completion:

2027-05-31

Conditions

• Healthy Participants

Interventions

• DEVICE

No Results Yet

NCT07218588 | COMPLETED | NA

40 participants

Sanctuary Farm Prescription in Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-11-20

Completion:

2026-06-30

Conditions

• Obesity &Amp; Overweight
• Adolescence

Interventions

• OTHER

No Results Yet

NCT07218029 | RECRUITING | PHASE3

815 participants

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-05-12

Completion:

2028-12-07

Conditions

• Pulmonary Arterial Hypertension

Interventions

• BIOLOGICAL

No Results Yet

NCT07210528 | ACTIVE_NOT_RECRUITING | PHASE1

48 participants

Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-30

Completion:

2026-09-30

Conditions

• Mild Cognitive Impairment (MCI)
• Alzheimer Dementia (AD)

Interventions

• DRUG

No Results Yet

NCT07204483 | COMPLETED | NA

45 participants

Feasibility Trial of Functional Clothing, Moderate Exercise, and Health Information for Stress Reduction and Behavior Change in Okinawa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-16

Completion:

2026-03-26

Conditions

• Obesity
• Metabolic Syndrome
• Stress, Psychological

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT07202598 | RECRUITING | PHASE2

10 participants

Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-11-12

Completion:

2031-03-31

Conditions

• Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Enteritis

Interventions

• DRUG

No Results Yet

NCT07199231 | ACTIVE_NOT_RECRUITING

20 participants

OpenEvidence Safety and Comparative Efficacy of Four LLM's in Clinical Practice

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-01

Completion:

2026-07-30

Conditions

• AI (Artificial Intelligence)
• Large Language Model
• Generative Artificial Intelligence

Interventions

• OTHER

No Results Yet

NCT07198074 | RECRUITING | PHASE3

255 participants

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-01-27

Completion:

2028-07-01

Conditions

• Advanced Endometrial Carcinoma
• Recurrent Endometrial Carcinoma

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT07197502 | RECRUITING | NA

30 participants

Treatment of Borderline Personality Disorder With rTMS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-01

Completion:

2027-12-31

Conditions

• Borderline Personality Disorder
• Borderline Personality
• BPD - Borderline Personality Disorder

Interventions

• DEVICE

No Results Yet

NCT07195591 | RECRUITING | PHASE3

766 participants

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-12-10

Completion:

2031-12-31

Conditions

• Glioblastoma

Interventions

• RADIATION
• DRUG
• DEVICE

No Results Yet

NCT07194382 | RECRUITING | PHASE2

160 participants

AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02 (Nintedanib Solution) in IPF

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-03-10

Completion:

2026-12-31

Conditions

• Idiopathic Pulmonary Fibrosis (IPF)

Interventions

• DRUG

No Results Yet

NCT07194187 | NOT_YET_RECRUITING | NA

17 participants

High Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet Obstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-09-01

Completion:

2027-12-31

Conditions

• Bladder Outlet Obstruction
• BPH

Interventions

• DEVICE

No Results Yet

NCT07190690 | RECRUITING | NA

2100 participants

Comparison of a Contemporary Sirolimus-eluting Stent (ihtDEStiny®) With Another Everolimus-eluting Stent (Xience™), Both With Permanent Polymers, in Patients With Acute Coronary Syndrome and de Novo Coronary Artery Lesions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-12-19

Completion:

2029-10-15

Conditions

• Coronary Artery Disease

Interventions

• DEVICE

No Results Yet

NCT07188740 | RECRUITING | PHASE1

32 participants

Metformin Inhibits DNMT3A Clonal Hematopoiesis in Acute Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-30

Completion:

2027-08-30

Conditions

• DNMT3A Gene Mutation

Interventions

• DRUG

No Results Yet

NCT07186595 | COMPLETED | PHASE4

75 participants

A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-25

Completion:

2026-07-08

Conditions

• Mid Face Volume Deficit

Interventions

• DEVICE

No Results Yet

NCT07183527 | RECRUITING | NA

1750 participants

Hybrid Type I Effectiveness-implementation Cluster Randomized Controlled Trial of CARES

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-08-08

Completion:

2030-01-10

Conditions

• CARES
• Standard of Care

Interventions

• BEHAVIORAL

No Results Yet

NCT07180537 | RECRUITING | NA

400 participants

Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-12-01

Completion:

2027-12-31

Conditions

• Rheumatoid Arthritis
• Sjogren's Syndrome
• Systemic Lupus Erythematosus
• Mixed Connective Tissue Disease
• Psoriatic Arthritis
• Anxiety Disorders
• Depressive Disorders
• Moderate Depression
• Moderate Anxiety

Interventions

• BEHAVIORAL

No Results Yet

NCT07175038 | RECRUITING | PHASE2

40 participants

A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-01

Completion:

2027-03-31

Conditions

• Pulmonary Arterial Hypertension (PAH)
• Pulmonary Hypertension, Interstitial Lung Disease

Interventions

• DRUG

No Results Yet

NCT07174388 | RECRUITING

650 participants

An External Control Arm Study in Non-Small Cell Lung Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2026-01-07

Completion:

2029-04-30

Conditions

• Non Small Cell Lung Cancer

No Results Yet

NCT07169331 | ACTIVE_NOT_RECRUITING | PHASE4

16 participants

A Study to Evaluate the Efficacy and Safety of Zanubrutinib in Chinese Adults With Treatment-Naive Waldenström Macroglobulinemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-17

Completion:

2028-10-31

Conditions

• Waldenström's Macroglobulinemia

Interventions

• DRUG

No Results Yet

NCT07167927 | RECRUITING | NA

110 participants

Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-21

Completion:

2027-01-31

Conditions

• Children With Medical Complexity (CMC)
• Multiple Chronic Conditions
• Neuromuscular Scoliosis
• Shared Decision Making
• Decision Support Systems, Clinical
• Decision Aids

Interventions

• BEHAVIORAL

No Results Yet

NCT07161414 | RECRUITING | PHASE1

40 participants

A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-11-25

Completion:

2027-07-19

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT07159048 | RECRUITING | NA

120 participants

The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-15

Completion:

2026-10-31

Conditions

• Hepatocellular Carcinoma
• Colorectal Cancer Liver Metastasis

Interventions

• DEVICE

No Results Yet

NCT07154550 | RECRUITING | NA

100 participants

Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-02-11

Completion:

2032-11-30

Conditions

• Club Foot

Interventions

• DEVICE

No Results Yet

NCT07148089 | RECRUITING | PHASE1

18 participants

A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-02-23

Completion:

2027-06-30

Conditions

• Catecholaminergic Polymorphic Ventricular Tachycardia

Interventions

• DRUG

No Results Yet

NCT07146906 | RECRUITING | PHASE2

32 participants

A Study to Assess the Effects of Zigakibart on IgA Nephropathy.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-03-26

Completion:

2030-07-12

Conditions

• Immunoglobulin A Nephropathy (IgAN)

Interventions

• BIOLOGICAL

No Results Yet

NCT07143019 | RECRUITING | NA

214 participants

The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-03-16

Completion:

2027-07-31

Conditions

• Hemorrhagic Stroke
• Aneurysm, Intracranial
• Saccular Aneurysm
• Fusiform Aneurysm
• Brain Aneurysm

Interventions

• DEVICE

No Results Yet

NCT07142265 | RECRUITING

300 participants

Evaluation of 1-Year Clinical Outcomes With Early Inclisiran Initiation in Post-MI Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-30

Completion:

2027-09-30

Conditions

• Myocardial Infarction

No Results Yet

NCT07131059 | RECRUITING | NA

537 participants

MRD-positive AML Clinical Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-05-11

Completion:

2028-05-10

Conditions

• AML, Adult

Interventions

• DRUG

No Results Yet

NCT07130994 | RECRUITING | NA

15 participants

Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-05

Completion:

2027-09-30

Conditions

• Mitral Regurgitation
• Heart Disease

Interventions

• DEVICE

No Results Yet

NCT07126444 | RECRUITING

130 participants

Effects of an Exercise Snack Intervention on Employee Health and Work Performance

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-02

Completion:

2027-12-31

Conditions

• Occupational Stress

No Results Yet

NCT07112196 | RECRUITING | PHASE2/PHASE3

518 participants

Visugromab in Cachexia International Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-04-16

Completion:

2029-12-31

Conditions

• Cancer-associated Cachexia

Interventions

• DRUG

No Results Yet