Clinical Trials

NCT04288635 | RECRUITING

55 participants

Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-07-09
Completion:: 2027-07-09

Conditions

Septic Shock
Multiple Organ Failure

Interventions

BIOLOGICAL

No Results Yet

NCT04253964 | RECRUITING | PHASE2

105 participants

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-07-01
Completion:: 2027-09-01

Conditions

Nonsmall Cell Lung Cancer
Performance Status

Interventions

DRUG
OTHER

No Results Yet

NCT04242264 | COMPLETED | PHASE2

69 participants

Phase 2 Shigella Vaccine and Challenge

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-10-12
Completion:: 2024-03-11

Conditions

Immunisation
Shigella Infection

Interventions

OTHER
BIOLOGICAL

Results Available

NCT04236882 | ACTIVE_NOT_RECRUITING | NA

28 participants

Sleep and Physical Activity Intervention for Increasing Physical Activity in Overweight or Obese and Sedentary African Americans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-10-04
Completion:: 2030-04-30

Conditions

Behavioral Disorder
Endocrine System Disorder

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT04224493 | ACTIVE_NOT_RECRUITING | PHASE3

599 participants

A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-06-11
Completion:: 2027-02-13

Conditions

Relapsed/Refractory Follicular Lymphoma
Follicular Lymphoma
Refractory Follicular Lymphoma

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT04219280 | ACTIVE_NOT_RECRUITING | PHASE4

100 participants

Evaluating Treatment of ADHD in Children With Down Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-10-02
Completion:: 2026-08-31

Conditions

Down Syndrome
ADHD

Interventions

DRUG

No Results Yet

NCT04210687 | ACTIVE_NOT_RECRUITING | NA

90 participants

Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-03-09
Completion:: 2026-12-01

Conditions

Thumb Osteoarthritis

Interventions

PROCEDURE

No Results Yet

NCT04197934 | ACTIVE_NOT_RECRUITING | PHASE1

56 participants

WSD0922-FU for Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-12-20
Completion:: 2022-10-30

Conditions

Anaplastic Astrocytoma, IDH-Wildtype
Glioblastoma, IDH-Wildtype
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Central Nervous System
Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE
DRUG

No Results Yet

NCT04171622 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

Lenvatinib and Pembrolizumab for the Treatment of Stage IVB Locally Advanced and Unresectable or Stage IVC Metastatic Anaplastic Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-11-04
Completion:: 2027-08-31

Conditions

Metastatic Thyroid Gland Carcinoma
Poorly Differentiated Thyroid Gland Carcinoma
Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8
Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8
Thyroid Gland Squamous Cell Carcinoma
Unresectable Thyroid Gland Carcinoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04118998 | ACTIVE_NOT_RECRUITING | NA

86 participants

Progressive Abduction Loading Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-08-27
Completion:: 2026-07-07

Conditions

Stroke, Acute

Interventions

BEHAVIORAL

No Results Yet

NCT04108741 | TERMINATED | NA

39 participants

Augmented Reality Treadmill Training in Patients With Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-09-15
Completion:: 2025-06-10

Conditions

Parkinson Disease
Fall

Interventions

DEVICE

No Results Yet

NCT04107311 | ACTIVE_NOT_RECRUITING

120 participants

Prospective Analysis of Intestinal Microbiome and Autoimmune Panels as Predictors of Toxicity in ImmunOncology Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-09-05
Completion:: 2027-03-05

Conditions

Solid Tumor

No Results Yet

NCT04106973 | TERMINATED

12 participants

Mesothelioma Early Detection by VOCs

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-06-05
Completion:: 2022-01-01

Conditions

Pleural Mesothelioma
Asbestos Exposure
Pleural Plaque

No Results Yet

NCT04072211 | COMPLETED | PHASE4

641 participants

Demonstration Project on Health Care Worker Protection Against Hepatitis B in Kalulushi District

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-11-25
Completion:: 2020-08-30

Conditions

Hepatitis B Virus
Health Care Associated Infection

Interventions

BIOLOGICAL

No Results Yet

NCT04044365 | ACTIVE_NOT_RECRUITING

139 participants

Pediatric cGVHD Symptom Scale

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-10-02
Completion:: 2026-12-31

Conditions

Graft vs Host Disease

No Results Yet

NCT04026516 | COMPLETED | NA

29 participants

CAVA: Dizziness Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-07-01
Completion:: 2025-10-31

Conditions

Meniere's Disease
Benign Paroxysmal Positional Vertigo
Recurrent Vestibulopathy
Vestibular Migraine

Interventions

DEVICE

No Results Yet

NCT03965234 | RECRUITING | PHASE1/PHASE2

99 participants

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-07-16
Completion:: 2029-05-25

Conditions

Metastatic Bone Sarcoma
Metastatic Malignant Neoplasm in the Lung
Metastatic Soft Tissue Sarcoma
Metastatic Unresectable Sarcoma
Resectable Sarcoma
Colorectal Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03959800 | RECRUITING

1600 participants

Molecular Basis of Pediatric Liver Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2015-06-22
Completion:: 2030-06-30

Conditions

Childhood Liver Cancer
Liver Malignant Tumors
Embryonal Sarcoma of Liver (Disorder)
Hepatoblastoma
Hepatocellular Carcinoma
Rhabdoid Tumor of Liver

No Results Yet

NCT03946878 | ACTIVE_NOT_RECRUITING | PHASE2

32 participants

Venetoclax and Acalabrutinib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-08-13
Completion:: 2028-02-08

Conditions

Blastoid Variant Mantle Cell Lymphoma
CCND1 Protein Overexpression
CD20 Positive
CD5 Positive
FCER2 Negative
Pleomorphic Variant Mantle Cell Lymphoma
Recurrent Mantle Cell Lymphoma
Refractory Mantle Cell Lymphoma
t(11;14)(q13;q32)

Interventions

DRUG

No Results Yet

NCT03931694 | COMPLETED

113 participants

E-health Tool for Management of Chronic Pain Patients.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-02-06
Completion:: 2020-06-04

Conditions

Chronic Pain

Interventions

DEVICE

No Results Yet

NCT03884075 | RECRUITING | PHASE2

104 participants

Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-07-24
Completion:: 2027-09-03

Conditions

Non-Alcoholic Steatohepatitis
Non-Alcoholic Fatty Liver Disease

Interventions

DRUG

No Results Yet

NCT03859128 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

427 participants

Toripalimab or Placebo as Adjuvant Therapy in Hepatocellular Carcinoma After Radical Resection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-03-05
Completion:: 2026-12-31

Conditions

Hepatocellular Carcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT03851614 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-04-08
Completion:: 2027-01-01

Conditions

Mismatch Repair Proficient Colorectal Cancer
Pancreatic Adenocarcinoma
Leiomyosarcoma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT03843385 | ACTIVE_NOT_RECRUITING | PHASE3

84 participants

Transfer of FRozen Encapsulated Multidonor Stool Filtrate for Active Ulcerative COlitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-01-31
Completion:: 2026-08-31

Conditions

Ulcerative Colitis
Inflammatory Bowel Diseases

Interventions

DRUG

No Results Yet

NCT03838939 | COMPLETED | NA

120 participants

Biotherapies and Therapeutic Education in Chronic Inflammatory Rheumatism

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-01-21
Completion:: 2021-12-10

Conditions

Rheumatoid Arthritis
Spondyloarthritis

Interventions

OTHER

No Results Yet

NCT03831386 | ACTIVE_NOT_RECRUITING | NA

200 participants

Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-01-31
Completion:: 2026-12-31

Conditions

Pleural Effusion

Interventions

PROCEDURE

No Results Yet

NCT03824652 | RECRUITING | PHASE2

50 participants

WALNUTS for POWER: Polyphenols, Omega-3 Fatty Acids, Weight Loss, and EneRgy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-04-22
Completion:: 2026-12-31

Conditions

Prostate Cancer

Interventions

OTHER

No Results Yet

NCT03744845 | COMPLETED | NA

40 participants

The Use of Virtual Reality to Reduce Anxiety and Pain in Perioperative Settings

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2018-12-10
Completion:: 2024-05-15

Conditions

Perioperative Pain
Perioperative Anxiety

Interventions

OTHER

No Results Yet

NCT03744390 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

IDH2 (AG 221) Inhibitor in Patients With IDH2 Mutated Myelodysplastic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-04-02
Completion:: 2023-02-18

Conditions

Myelodysplastic Syndromes
Leukemia Acute Myeloid

Interventions

DRUG

No Results Yet

NCT03741673 | ACTIVE_NOT_RECRUITING | PHASE3

180 participants

Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2018-11-08
Completion:: 2027-01-31

Conditions

Malignant Neoplasm
Metastatic Malignant Neoplasm in the Brain

Interventions

OTHER
RADIATION

No Results Yet

NCT03691922 | COMPLETED | NA

62 participants

Erector Spinae Block Versus Shoulder Periarticular Anesthetic Infiltration for Arthroscopic Shoulder Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-07-06
Completion:: 2020-02-01

Conditions

Arthroscopic Shoulder Surgery

Interventions

PROCEDURE

No Results Yet

NCT03606967 | RECRUITING | PHASE2

86 participants

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-04-13
Completion:: 2026-12-30

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Invasive Breast Carcinoma
Metastatic Triple-Negative Breast Carcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT03575169 | COMPLETED

26 participants

The Use of Bispectral Index Monitoring to Assess Depth of Sedation in Patients With Traumatic Brain Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-07-01
Completion:: 2022-12-31

Conditions

Traumatic Brain Injury

Interventions

DEVICE

Results Available

NCT03542409 | COMPLETED | EARLY_PHASE1

53 participants

Safety and Feasibility of Preoperative and Intraoperative Image-Guided Resection of Gliomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2017-02-15
Completion:: 2021-10-28

Conditions

Brain Tumor Adult

Interventions

DEVICE

No Results Yet

NCT03503409 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

IDH1 (AG 120) Inhibitor in Patients With IDH1 Mutated Myelodysplastic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-05-14
Completion:: 2027-04-02

Conditions

Myelodysplastic Syndromes
Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT03453112 | COMPLETED | PHASE3

494 participants

Foster 100/6 mg NEXThaler Versus Foster 100/6mg Pressurized Metered-dose Inhaler (pMDI) in Patients With Controlled Asthma.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2017-10-09
Completion:: 2021-12-28

Conditions

Asthma

Interventions

DRUG

Results Available

NCT03441061 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2018-02-15
Completion:: 2027-02-28

Conditions

Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia
Recurrent B Acute Lymphoblastic Leukemia

Interventions

BIOLOGICAL

No Results Yet

NCT03437135 | COMPLETED

172 participants

Screening and Characterization of Hearing Disorders in Diabetic Persons

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2015-12-01
Completion:: 2020-12-14

Conditions

Diabetes
Hearing Problems

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03418818 | ACTIVE_NOT_RECRUITING | NA

70 participants

FAZA PET/MRI Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2018-03-27
Completion:: 2028-10-31

Conditions

Sarcoma

Interventions

DRUG

No Results Yet

NCT03407066 | RECRUITING

10200 participants

Perception, Sensation, Cognition and Action in Humans

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-03-26
Completion:: 2027-12-31

Conditions

Normal Physiology

No Results Yet